JP2017528715A - 細胞齢を決定するシステムと方法 - Google Patents

細胞齢を決定するシステムと方法 Download PDF

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Publication number
JP2017528715A
JP2017528715A JP2017513624A JP2017513624A JP2017528715A JP 2017528715 A JP2017528715 A JP 2017528715A JP 2017513624 A JP2017513624 A JP 2017513624A JP 2017513624 A JP2017513624 A JP 2017513624A JP 2017528715 A JP2017528715 A JP 2017528715A
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Prior art keywords
hba1c
fraction
cells
average
age
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Japanese (ja)
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JP2017528715A5 (https=
Inventor
アグトーヴェン アンドレー ヴァン,
アグトーヴェン アンドレー ヴァン,
ファブリス マレーグ,
ファブリス マレーグ,
クリストフ ゴデフロイ,
クリストフ ゴデフロイ,
エンリケ ラベリノ,
エンリケ ラベリノ,
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Beckman Coulter Inc
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Beckman Coulter Inc
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Publication of JP2017528715A5 publication Critical patent/JP2017528715A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/723Glycosylated haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/726Devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • G01N2015/014Reticulocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402Data analysis by thresholding or gating operations performed on the acquired signals or stored data
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477Multiparameters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1488Methods for deciding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805Haemoglobins; Myoglobins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2017513624A 2014-09-12 2015-09-11 細胞齢を決定するシステムと方法 Ceased JP2017528715A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462049970P 2014-09-12 2014-09-12
US62/049,970 2014-09-12
US201462059684P 2014-10-03 2014-10-03
US62/059,684 2014-10-03
PCT/US2015/049797 WO2016040870A1 (en) 2014-09-12 2015-09-11 Systems and methods to determine the age of cells

Publications (2)

Publication Number Publication Date
JP2017528715A true JP2017528715A (ja) 2017-09-28
JP2017528715A5 JP2017528715A5 (https=) 2018-09-27

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JP2017513624A Ceased JP2017528715A (ja) 2014-09-12 2015-09-11 細胞齢を決定するシステムと方法

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Country Link
US (1) US10739357B2 (https=)
EP (1) EP3191848A1 (https=)
JP (1) JP2017528715A (https=)
CN (1) CN106716138B (https=)
WO (1) WO2016040870A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023073397A (ja) * 2018-10-26 2023-05-25 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3013360B1 (fr) * 2013-11-19 2015-12-04 Snecma Procede integre de frittage pour microfissuration et tenue a l'erosion des barrieres thermiques
EP3602003B1 (en) * 2017-03-31 2026-04-22 Life Technologies Corporation Apparatuses, systems and methods for imaging flow cytometry
CN115004310A (zh) 2019-11-25 2022-09-02 雅培糖尿病护理公司 用于生理参数分析的方法、设备和系统
JP2021103139A (ja) * 2019-12-25 2021-07-15 ソニーグループ株式会社 情報処理装置、粒子測定装置、粒子測定システム、粒子分取装置、粒子分取システム、情報処理方法、及び情報処理プログラム
CN112305207B (zh) * 2020-10-20 2023-03-10 上海交通大学 基于HbA1c和血糖浓度为传感变量的红细胞平均寿命检测方法
WO2024094854A1 (en) * 2022-11-03 2024-05-10 Institut National de la Santé et de la Recherche Médicale Method for determining the relative age of red blood cells
WO2025210140A1 (en) * 2024-04-04 2025-10-09 Institut National de la Santé et de la Recherche Médicale Method for determining the age of red blood cells

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099301A1 (en) * 2005-10-28 2007-05-03 Tyvoll David A Systems and methods for measuring glycated hemoglobin
JP2010500570A (ja) * 2006-08-09 2010-01-07 ベックマン コールター,インコーポレイティド 細胞ヘモグロビンの測定方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69212999T2 (de) 1991-04-08 1997-03-27 Chronomed Inc Verfahren zur Analyse der Glykierung von Hämoglobin
US7534618B2 (en) * 2005-10-28 2009-05-19 Hewlett-Packard Development Company, L.P. Systems and methods for measuring glycated hemoglobin
US7968279B2 (en) 2008-08-13 2011-06-28 Beckman Coulter, Inc. Reference control for cell by cell analysis
EP2433140B1 (en) 2009-05-20 2015-02-11 Relia Diagnostic Systems, Inc. Systems and methods for determining the percentage of glycated hemoglobin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099301A1 (en) * 2005-10-28 2007-05-03 Tyvoll David A Systems and methods for measuring glycated hemoglobin
JP2010500570A (ja) * 2006-08-09 2010-01-07 ベックマン コールター,インコーポレイティド 細胞ヘモグロビンの測定方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023073397A (ja) * 2018-10-26 2023-05-25 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム
JP7463590B2 (ja) 2018-10-26 2024-04-08 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム
JP2024079874A (ja) * 2018-10-26 2024-06-12 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム

Also Published As

Publication number Publication date
WO2016040870A9 (en) 2017-04-06
US20180231573A1 (en) 2018-08-16
US10739357B2 (en) 2020-08-11
EP3191848A1 (en) 2017-07-19
WO2016040870A1 (en) 2016-03-17
CN106716138B (zh) 2019-06-14
CN106716138A (zh) 2017-05-24

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