JP2017528463A - 四級アンモニウム化合物を含有する消毒組成物 - Google Patents
四級アンモニウム化合物を含有する消毒組成物 Download PDFInfo
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/26—Phosphorus; Compounds thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
- A01N37/04—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof polybasic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
- A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/10—Animals; Substances produced thereby or obtained therefrom
Abstract
Description
本出願は、2014年9月9日出願の米国特許出願第62/047806号明細書に対する優先権を主張し、この出願は参照によりその全体が本明細書に組み込まれる。
を有するものが挙げられるが、これに限定されず、
式中、R1はベンジル基、C1〜C22アルキル、または任意選択的にアリール置換アルキル基であり;
R2およびR3は独立して、任意選択的に置換されているC1〜C22アルキル基であり;
R4は、C1〜C22アルキルまたはアリール置換アルキル基、ベンジル基、および−[(CH2)2−O]n−R5(式中、nは、1〜20の整数であり、かつR5は、水素、フェニル、アルキル、およびアルキル置換フェニルからなる群から選択される)からなる群から選択され;および
X−は、塩素、臭素、ならびにリン酸イオン、硫酸イオン、および硝酸イオンである。
黄色ブドウ球菌(Staphylococcus aureus)および緑膿菌(Pseudomonas aeruginosa)に対する殺生物活性。
例示した組成物の殺生物活性を、OECD Quantitative Method for Evaluating Bacterial Activity of Microbiocides Used on Hard Non−Porous Surfacesを用いて判定した。
枯草菌(Bacillus subtilis)に対する殺生物活性。
例示した組成物の殺生物活性を、OECD Quantitative Suspension Test for the Evaluation of Sporicidal Activity of Chemical Disinfectants used in Food, Industrial;Domestic and institutional areasを用いて判定した。中和を、リンス流体として1%カタラーゼを有するD/E Brothを用いた膜濾過によって実行した。試験を、干渉物質として0.3g/lウシアルブミンを用いて、20℃で60分間にわたり実行した。
Claims (32)
- 殺生物性四級アンモニウム化合物、過酸化水素、および少なくとも1つの酸またはその塩を含む消毒組成物。
- 二部消毒剤組成物であって、前記組成物の第1の部分が殺生物性四級アンモニウム化合物および少なくとも1つの酸またはその塩を含み、前記組成物の第2の部分が過酸化水素を含む、二部消毒剤組成物。
- 前記四級アンモニウム化合物は、式(I):
を有する化合物であり、
式中、R1は、任意選択的に置換されているベンジル基、または任意選択的に置換されているアルキルもしくはアリール置換アルキル基であり;
R2およびR3は独立して、任意選択的に置換されているアルキル基であり;
R4は、任意選択的に置換されているアルキルまたはアリール置換アルキル基、ベンジル基、および−[(CH2)2−O]n−R5(式中、nは、1〜20の整数であり、かつR5は、水素、フェニル、およびアルキル置換フェニルからなる群から選択される)からなる群から選択され;および
X−は、塩素、臭素、リン酸イオン、硫酸イオン、および硝酸イオンである、請求項1または2に記載の組成物。 - 前記四級アンモニウム化合物は、殺生物性四級アンモニウムクロリド化合物である、請求項1〜3の何れか一項に記載の組成物。
- R1およびR4は、同じベンジル基、またはC1〜22アルキルもしくはアリール置換アルキル基である、請求項3または4に記載の組成物。
- R1およびR4はC1〜22アルキルである、請求項3または4に記載の組成物。
- R1およびR4はC10アルキルである、請求項3または4に記載の組成物。
- R2およびR3はC1〜C4アルキルである、請求項3または4に記載の組成物。
- R2およびR3はメチルである、請求項3または4に記載の組成物。
- R1およびR4はC1〜22アルキルであり、かつR2およびR3はメチルである、請求項3または4に記載の組成物。
- 前記四級アンモニウム化合物は、ジデシルジメチルアンモニウムクロリドおよび/またはC8〜C18アルキルジメチルベンジルアンモニウムクロリドを含む、請求項1〜10の何れか一項に記載の組成物。
- 前記少なくとも1つの酸は、C1〜C8カルボン酸またはその塩である、請求項1〜11の何れか一項に記載の組成物。
- 前記少なくとも1つの酸は、モノカルボン酸、ジカルボン酸、トリカルボン酸、またはそれらの混合物である、請求項1〜12の何れか一項に記載の組成物。
- 前記酸は、メタンスルホン酸、リン酸、クエン酸、エチドロン酸、フィチン酸、ホスホノ酢酸、N−(ホスホノメチル)イミノ二酢酸、ジエチレントリアミンペンタキス(メチルホスホン酸)、S,S−エチレンジアミン−N’N’−ジコハク酸三ナトリウム塩、スズ酸ナトリウム、それらの塩、およびそれらの任意の混合物からなる群から選択される、請求項1〜13の何れか一項に記載の組成物。
- 前記酸は、前記酸のアルカリ金属塩の形態である、請求項1〜14の何れか一項に記載の組成物。
- 前記四級アンモニウム化合物の濃度が前記組成物の約0.1重量%〜約25重量%である希釈可能組成物である、請求項1〜15の何れか一項に記載の組成物。
- 過酸化水素の濃度が前記組成物の約0.5重量%〜約25重量%である希釈可能組成物である、請求項1〜16の何れか一項に記載の組成物。
- 前記酸またはその塩の濃度が前記組成物の約0.01重量%〜約25重量%である希釈可能組成物である、請求項1〜17の何れか一項に記載の組成物。
- 前記四級アンモニウム化合物の濃度が前記組成物の約0.03重量%〜約1.5重量%である、直ちに使用できる組成物である、請求項1〜15の何れか一項に記載の組成物。
- 過酸化水素の濃度が前記組成物の約0.06重量%〜約2重量%である、直ちに使用できる組成物である、請求項1〜15または19の何れか一項に記載の組成物。
- 前記組成物中の前記酸またはその塩の濃度が前記組成物の約0.05重量%〜約6重量%である希釈可能組成物である、請求項1〜18の何れか一項に記載の組成物。
- 前記四級アンモニウム化合物、前記過酸化水素、および前記少なくとも1つの酸またはその塩の組合せは、前記過酸化水素または前記四級アンモニウム化合物のみと比較して抗菌効能を高める、請求項1〜21の何れか一項に記載の組成物。
- 溶媒をさらに含む、請求項1〜22の何れか一項に記載の組成物。
- 前記溶媒は、水、エタノール、プロパノール、イソプロパノール、プロピレングリコール、ジプロピレングリコールn−プロピルエーテル、およびジプロピレングリコールメチルエーテルからなる群から選択される、請求項23に記載の組成物。
- キレート剤および/または腐食防止剤をさらに含む、請求項1〜24の何れか一項に記載の組成物。
- 非イオン性界面活性剤、イオン性界面活性剤、過酸化水素安定化剤、色素、芳香剤、泡止め剤、pHバッファ、pH調整剤、および/またはそれらの混合物をさらに含む、請求項1〜25の何れか一項に記載の組成物。
- 請求項1〜26の何れか一項に記載の組成物を表面に塗布することを含む、表面上の微生物を殺すか、またはその増殖を阻止する方法。
- 前記微生物は、グラム陽性菌、グラム陰性菌、ウィルス、菌類、カビ、または糸状菌の1つまたは複数を含む、請求項27に記載の方法。
- 前記微生物は、ブドウ球菌(Staphylococcus)属、シュードモナス(Pseudomonas)属、肝炎、ロタウィルス、ライノウィルス、またはマイコバクテリウム・テラエ(Mycobacterium terrae)の1つまたは複数を含む、請求項27または28に記載の方法。
- 表面を消毒する方法であって、前記表面に請求項1〜26の何れか一項に記載の組成物を塗布することを含む方法。
- 表面上の微生物を殺すか、またはその増殖を阻止するための、請求項1〜26の何れか一項に記載の組成物の使用。
- 表面を消毒するための、請求項1〜26の何れか一項に記載の組成物の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201462047806P | 2014-09-09 | 2014-09-09 | |
US62/047,806 | 2014-09-09 | ||
PCT/US2015/048792 WO2016040230A1 (en) | 2014-09-09 | 2015-09-08 | Disinfectant composition containing quaternary ammonium compounds |
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JP2020097046A Division JP2020147586A (ja) | 2014-09-09 | 2020-06-03 | 四級アンモニウム化合物を含有する消毒組成物 |
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JP2017528463A true JP2017528463A (ja) | 2017-09-28 |
JP7149072B2 JP7149072B2 (ja) | 2022-10-06 |
JP7149072B6 JP7149072B6 (ja) | 2024-02-02 |
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JP2017513184A Active JP7149072B6 (ja) | 2014-09-09 | 2015-09-08 | 四級アンモニウム化合物を含有する消毒組成物 |
JP2020097046A Pending JP2020147586A (ja) | 2014-09-09 | 2020-06-03 | 四級アンモニウム化合物を含有する消毒組成物 |
JP2022113572A Pending JP2022145703A (ja) | 2014-09-09 | 2022-07-15 | 四級アンモニウム化合物を含有する消毒組成物 |
JP2024013997A Pending JP2024045382A (ja) | 2014-09-09 | 2024-02-01 | 四級アンモニウム化合物を含有する消毒組成物 |
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JP2020097046A Pending JP2020147586A (ja) | 2014-09-09 | 2020-06-03 | 四級アンモニウム化合物を含有する消毒組成物 |
JP2022113572A Pending JP2022145703A (ja) | 2014-09-09 | 2022-07-15 | 四級アンモニウム化合物を含有する消毒組成物 |
JP2024013997A Pending JP2024045382A (ja) | 2014-09-09 | 2024-02-01 | 四級アンモニウム化合物を含有する消毒組成物 |
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US (1) | US10285400B2 (ja) |
EP (1) | EP3190883A1 (ja) |
JP (4) | JP7149072B6 (ja) |
CN (1) | CN107072216B (ja) |
CA (1) | CA2959052C (ja) |
MX (1) | MX2017002916A (ja) |
WO (1) | WO2016040230A1 (ja) |
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JP2024045382A (ja) | 2024-04-02 |
BR112017004645A2 (pt) | 2018-05-08 |
CA2959052C (en) | 2023-10-03 |
CN107072216A (zh) | 2017-08-18 |
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