JP2017527304A5 - - Google Patents
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- JP2017527304A5 JP2017527304A5 JP2017523184A JP2017523184A JP2017527304A5 JP 2017527304 A5 JP2017527304 A5 JP 2017527304A5 JP 2017523184 A JP2017523184 A JP 2017523184A JP 2017523184 A JP2017523184 A JP 2017523184A JP 2017527304 A5 JP2017527304 A5 JP 2017527304A5
- Authority
- JP
- Japan
- Prior art keywords
- genes
- subject
- lung cancer
- identified
- clusters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000623 proteins and genes Proteins 0.000 claims 26
- 238000000034 method Methods 0.000 claims 16
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 11
- 201000005202 lung cancer Diseases 0.000 claims 11
- 208000020816 lung neoplasm Diseases 0.000 claims 11
- 230000014509 gene expression Effects 0.000 claims 9
- 239000012472 biological sample Substances 0.000 claims 7
- 108020004999 messenger RNA Proteins 0.000 claims 6
- -1 APOCI Proteins 0.000 claims 3
- 230000000391 smoking effect Effects 0.000 claims 3
- 230000002380 cytological effect Effects 0.000 claims 2
- 238000010195 expression analysis Methods 0.000 claims 2
- 102100026443 Adhesion G-protein coupled receptor F1 Human genes 0.000 claims 1
- 108010003133 Aldo-Keto Reductase Family 1 Member C2 Proteins 0.000 claims 1
- 102100024089 Aldo-keto reductase family 1 member C2 Human genes 0.000 claims 1
- 102100024217 CAMPATH-1 antigen Human genes 0.000 claims 1
- 108010065524 CD52 Antigen Proteins 0.000 claims 1
- 101150028614 CERS3 gene Proteins 0.000 claims 1
- 102100035435 Ceramide synthase 3 Human genes 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 102100035300 Cystine/glutamate transporter Human genes 0.000 claims 1
- 102100039353 Epoxide hydrolase 3 Human genes 0.000 claims 1
- 101150043847 FOXD1 gene Proteins 0.000 claims 1
- 102100037057 Forkhead box protein D1 Human genes 0.000 claims 1
- 102100040517 Golgi-associated kinase 1B Human genes 0.000 claims 1
- 101000718228 Homo sapiens Adhesion G-protein coupled receptor F1 Proteins 0.000 claims 1
- 101000812391 Homo sapiens Epoxide hydrolase 3 Proteins 0.000 claims 1
- 101000893979 Homo sapiens Golgi-associated kinase 1B Proteins 0.000 claims 1
- 101001030184 Homo sapiens Myotilin Proteins 0.000 claims 1
- 101000972799 Homo sapiens NKAP-like protein Proteins 0.000 claims 1
- 101000613391 Homo sapiens Protocadherin beta-16 Proteins 0.000 claims 1
- 101001134788 Homo sapiens Protocadherin beta-4 Proteins 0.000 claims 1
- 101100078258 Homo sapiens RUNX1T1 gene Proteins 0.000 claims 1
- 101000620773 Homo sapiens Ras GTPase-activating protein 3 Proteins 0.000 claims 1
- 101000839339 Homo sapiens Synaptotagmin-8 Proteins 0.000 claims 1
- 101000764274 Homo sapiens Troponin T, fast skeletal muscle Proteins 0.000 claims 1
- 102100038894 Myotilin Human genes 0.000 claims 1
- 102100022579 NKAP-like protein Human genes 0.000 claims 1
- 102100024952 Protein CBFA2T1 Human genes 0.000 claims 1
- 102100040927 Protocadherin beta-16 Human genes 0.000 claims 1
- 102100033435 Protocadherin beta-4 Human genes 0.000 claims 1
- 108700040655 RUNX1 Translocation Partner 1 Proteins 0.000 claims 1
- 102100022879 Ras GTPase-activating protein 3 Human genes 0.000 claims 1
- 108091006241 SLC7A11 Proteins 0.000 claims 1
- 102100028201 Synaptotagmin-8 Human genes 0.000 claims 1
- 102100026896 Troponin T, fast skeletal muscle Human genes 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 210000001533 respiratory mucosa Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462024456P | 2014-07-14 | 2014-07-14 | |
| US62/024,456 | 2014-07-14 | ||
| US201562160403P | 2015-05-12 | 2015-05-12 | |
| US62/160,403 | 2015-05-12 | ||
| PCT/US2015/040437 WO2016011068A1 (en) | 2014-07-14 | 2015-07-14 | Methods for evaluating lung cancer status |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020126239A Division JP2020182489A (ja) | 2014-07-14 | 2020-07-27 | 肺がん状態の評価方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527304A JP2017527304A (ja) | 2017-09-21 |
| JP2017527304A5 true JP2017527304A5 (cg-RX-API-DMAC7.html) | 2018-08-30 |
| JP6775499B2 JP6775499B2 (ja) | 2020-10-28 |
Family
ID=55078998
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523184A Active JP6775499B2 (ja) | 2014-07-14 | 2015-07-14 | 肺がん状態の評価方法 |
| JP2020126239A Pending JP2020182489A (ja) | 2014-07-14 | 2020-07-27 | 肺がん状態の評価方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020126239A Pending JP2020182489A (ja) | 2014-07-14 | 2020-07-27 | 肺がん状態の評価方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20160130656A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3169814B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6775499B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102461014B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN114807368A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015289758B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2954169A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016011068A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100035244A1 (en) | 2005-04-14 | 2010-02-11 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| AU2007223788B2 (en) | 2006-03-09 | 2012-11-29 | The Trustees Of Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| WO2009039457A1 (en) | 2007-09-19 | 2009-03-26 | The Trustees Of Boston University | Identification of novel pathways for drug development for lung disease |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| CN102459636B (zh) | 2009-05-07 | 2016-08-17 | 威拉赛特公司 | 用于诊断甲状腺病症的方法和组合物 |
| WO2014186036A1 (en) | 2013-03-14 | 2014-11-20 | Allegro Diagnostics Corp. | Methods for evaluating copd status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| JP7356788B2 (ja) | 2014-11-05 | 2023-10-05 | ベラサイト インコーポレイテッド | 機械学習および高次元転写データを使用して経気管支生検における特発性肺線維症を診断するシステムおよび方法 |
| JP2019522478A (ja) * | 2016-06-21 | 2019-08-15 | ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー | 遺伝子発現プロファイルを用いた肺癌の診断のための組成物及び方法 |
| WO2018009915A1 (en) | 2016-07-08 | 2018-01-11 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| KR102421109B1 (ko) * | 2016-09-14 | 2022-07-14 | 필립모리스 프로덕츠 에스.에이. | 개인의 생물학적 상태를 예측하기 위한 시스템, 방법 및 유전자 시그니처 |
| US11244764B2 (en) | 2016-12-21 | 2022-02-08 | Cerner Innovation, Inc. | Monitoring predictive models |
| CN110662844A (zh) | 2017-05-22 | 2020-01-07 | 内盖夫生物技术国家研究所有限公司 | 用于肺癌的诊断的生物标志物 |
| JP2020522690A (ja) * | 2017-06-02 | 2020-07-30 | ベラサイト インコーポレイテッド | 肺疾病の特定又はモニタリング方法及びシステム |
| WO2019126343A1 (en) | 2017-12-19 | 2019-06-27 | The Wistar Institute Of Anatomy And Biology | Compositions and methods for diagnosing lung cancers using gene expression profiles |
| US12023149B2 (en) | 2018-07-02 | 2024-07-02 | 3M Innovative Properties Company | Sensing system and method for monitoring time-dependent processes |
| KR102274564B1 (ko) * | 2018-07-03 | 2021-07-07 | (주) 프로큐라티오 | 빅데이터분석기반 암진단장치 |
| CN108998531B (zh) * | 2018-08-31 | 2021-10-01 | 昆明医科大学第一附属医院 | 肺癌下调长链非编码rna标志物及其应用 |
| CN109615075B (zh) * | 2018-12-14 | 2022-08-19 | 大连海事大学 | 一种基于多层聚类模型的居民日常行为识别方法 |
| US20210287795A1 (en) * | 2020-03-12 | 2021-09-16 | Optellum Limited | Cad device and method for assisting an estimation of lung disease from medical images |
| CN114277139B (zh) * | 2020-03-30 | 2022-09-02 | 中国医学科学院肿瘤医院 | 外泌体arpc5、snhg5等在肺癌诊断中的应用 |
| CN113930505B (zh) * | 2020-03-30 | 2022-04-19 | 中国医学科学院肿瘤医院 | 用于肺癌诊断的试剂盒及装置 |
| CN111863130A (zh) * | 2020-04-07 | 2020-10-30 | 至本医疗科技（上海）有限公司 | 肿瘤免疫治疗预后标志物的筛选方法及应用 |
| CN112034185A (zh) * | 2020-09-11 | 2020-12-04 | 上海市胸科医院 | Gpr110、vegfr、cd34在鉴别肺腺癌亚型中的用途 |
| IL306044A (en) * | 2021-03-29 | 2023-11-01 | Veracyte Inc | Methods and systems for identifying health disorders |
| US12094107B2 (en) * | 2021-04-07 | 2024-09-17 | Optellum Limited | CAD device and method for analyzing medical images |
| CN113444796B (zh) * | 2021-06-29 | 2023-02-07 | 浙江医院 | 与肺癌相关的生物标志物及其在诊断癌症中的应用 |
| KR102417602B1 (ko) * | 2021-11-30 | 2022-07-07 | (주)플라스바이오 | 인공 지능 모델 기반 종양 관리 장치 및 방법 |
| CN114854755B (zh) * | 2022-05-30 | 2023-05-23 | 陕西师范大学 | 一种抑制vstm2l表达的慢病毒载体及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003234623A1 (en) * | 2002-05-16 | 2003-12-02 | Euro-Celtique, S.A. | Use of gastrin releasing peptide (grp) and its receptor in cancer screening |
| WO2005000098A2 (en) * | 2003-06-10 | 2005-01-06 | The Trustees Of Boston University | Detection methods for disorders of the lung |
| US20070148650A1 (en) | 2003-11-12 | 2007-06-28 | Trustees Of Boston University | Isolation of nucleic acid from mouth epithelial cells |
| US20100035244A1 (en) * | 2005-04-14 | 2010-02-11 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| US9347945B2 (en) * | 2005-12-22 | 2016-05-24 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
| AU2007223788B2 (en) | 2006-03-09 | 2012-11-29 | The Trustees Of Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| EP2035583A2 (en) * | 2006-05-30 | 2009-03-18 | Duke University | Prediction of lung cancer tumor recurrence |
| KR101443214B1 (ko) * | 2007-01-09 | 2014-09-24 | 삼성전자주식회사 | 폐암 환자 또는 폐암 치료를 받은 폐암 환자의 폐암 재발 위험을 진단하기 위한 조성물, 키트 및 마이크로어레이 |
| AU2008251877A1 (en) | 2007-05-08 | 2008-11-20 | Picobella Llc | Methods for diagnosing and treating prostate and lung cancer |
| WO2009039457A1 (en) | 2007-09-19 | 2009-03-26 | The Trustees Of Boston University | Identification of novel pathways for drug development for lung disease |
| CA2719805A1 (en) | 2008-03-28 | 2009-10-01 | Trustees Of Boston University | Multifactorial methods for detecting lung disorders |
| GB0811413D0 (en) * | 2008-06-20 | 2008-07-30 | Kanton Basel Stadt | Gene expression signatures for lung cancers |
| SG186953A1 (en) * | 2010-07-09 | 2013-02-28 | Somalogic Inc | Lung cancer biomarkers and uses thereof |
| KR20130017525A (ko) * | 2011-08-11 | 2013-02-20 | 주식회사 젠닥스 | 대장암, 유방암, 신장암 또는 갑상선암의 조기 진단을 위한 바이오 마커 및 이의 용도 |
| AU2012300375A1 (en) * | 2011-08-29 | 2014-03-20 | Cardiodx, Inc. | Methods and compositions for determining smoking status |
| CA2799163C (en) * | 2011-12-18 | 2025-01-07 | 20/20 Genesystems, Inc. | METHODS AND ALGORITHMS TO AID IN CANCER DETECTION |
| US20150088430A1 (en) | 2012-04-26 | 2015-03-26 | Allegro Diagnostics Corp | Methods for evaluating lung cancer status |
| US20140220006A1 (en) * | 2013-02-01 | 2014-08-07 | Meso Scale Technologies, Llc | Lung cancer biomarkers |
-
2015
- 2015-07-14 WO PCT/US2015/040437 patent/WO2016011068A1/en not_active Ceased
- 2015-07-14 CN CN202210456480.7A patent/CN114807368A/zh active Pending
- 2015-07-14 JP JP2017523184A patent/JP6775499B2/ja active Active
- 2015-07-14 CA CA2954169A patent/CA2954169A1/en active Pending
- 2015-07-14 CN CN201580048833.8A patent/CN106795565B/zh active Active
- 2015-07-14 AU AU2015289758A patent/AU2015289758B2/en active Active
- 2015-07-14 US US14/799,472 patent/US20160130656A1/en not_active Abandoned
- 2015-07-14 EP EP15822338.8A patent/EP3169814B1/en active Active
- 2015-07-14 KR KR1020177004127A patent/KR102461014B1/ko active Active
- 2015-07-14 EP EP21185798.2A patent/EP3916110A1/en active Pending
-
2020
- 2020-05-15 US US16/875,673 patent/US20210040562A1/en not_active Abandoned
- 2020-07-27 JP JP2020126239A patent/JP2020182489A/ja active Pending
-
2021
- 2021-08-20 AU AU2021218178A patent/AU2021218178A1/en not_active Abandoned
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