JP2017524017A5 - - Google Patents

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Publication number
JP2017524017A5
JP2017524017A5 JP2017507968A JP2017507968A JP2017524017A5 JP 2017524017 A5 JP2017524017 A5 JP 2017524017A5 JP 2017507968 A JP2017507968 A JP 2017507968A JP 2017507968 A JP2017507968 A JP 2017507968A JP 2017524017 A5 JP2017524017 A5 JP 2017524017A5
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JP
Japan
Prior art keywords
alkyl
benzenesulfonamide
sulfonamide
fluoroquinolin
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017507968A
Other languages
English (en)
Japanese (ja)
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JP6770507B2 (ja
JP2017524017A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/045174 external-priority patent/WO2016025779A1/en
Publication of JP2017524017A publication Critical patent/JP2017524017A/ja
Publication of JP2017524017A5 publication Critical patent/JP2017524017A5/ja
Application granted granted Critical
Publication of JP6770507B2 publication Critical patent/JP6770507B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017507968A 2014-08-14 2015-08-14 ユビキチン化阻害物質として有用なキノリン誘導体 Expired - Fee Related JP6770507B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462037449P 2014-08-14 2014-08-14
US62/037,449 2014-08-14
PCT/US2015/045174 WO2016025779A1 (en) 2014-08-14 2015-08-14 Quinoline derivatives useful as ubiquitination inhibitors

Publications (3)

Publication Number Publication Date
JP2017524017A JP2017524017A (ja) 2017-08-24
JP2017524017A5 true JP2017524017A5 (https=) 2018-09-27
JP6770507B2 JP6770507B2 (ja) 2020-10-14

Family

ID=53938449

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017507968A Expired - Fee Related JP6770507B2 (ja) 2014-08-14 2015-08-14 ユビキチン化阻害物質として有用なキノリン誘導体

Country Status (5)

Country Link
US (1) US10040766B2 (https=)
EP (1) EP3180328B1 (https=)
JP (1) JP6770507B2 (https=)
CA (1) CA2958142A1 (https=)
WO (1) WO2016025779A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7198221B2 (ja) * 2017-04-20 2022-12-28 ゴーダーヴァリ バイオリファイナリーズ リミテッド 抗癌化合物
US11213701B2 (en) * 2018-12-01 2022-01-04 Russell Dahl Neuroprotective quinoline sulfonamides
US20240148744A1 (en) * 2021-02-09 2024-05-09 Celgene Corporation Sulfonamides and their use for treatment of helminthic infections and diseases
CN117865886B (zh) * 2024-03-07 2024-05-10 中国药科大学 一种n-(喹啉-8-基)喹啉-8-磺酰胺类化合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7915293B2 (en) 2003-05-30 2011-03-29 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
US20070254894A1 (en) * 2006-01-10 2007-11-01 Kane John L Jr Novel small molecules with selective cytotoxicity against human microvascular endothelial cell proliferation
WO2008074068A1 (en) 2006-12-20 2008-06-26 Prana Biotechnology Limited Substituted quinoline derivatives as antiamyloidogeneic agents
WO2009137597A1 (en) * 2008-05-06 2009-11-12 The Trustees Of Columbia University In The City Of New York COMPOUNDS THAT INHIBIT PRODUCTION OF sAPPβ AND Aβ AND USES THEREOF
WO2010051064A1 (en) * 2008-10-30 2010-05-06 The Trustees Of Columbia University In The City Of New York COMPOUNDS THAT INHIBIT NFκB ACTIVITY
US20120214803A1 (en) * 2011-02-18 2012-08-23 Vifor (International) Ag Novel Sulfonaminoquinoline Hepcidin Antagonists
WO2012122534A2 (en) 2011-03-10 2012-09-13 The Trustees Of Columbia University In The City Of New York N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation
US9200046B2 (en) * 2011-06-29 2015-12-01 Cornell University Reporter system for high throughput screening of compounds and uses thereof
WO2013052943A2 (en) * 2011-10-06 2013-04-11 The Regents Of The University Of Michgian Small molecule inhibitors of mcl-1 and uses thereof

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