JP2017520569A5 - - Google Patents

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Publication number
JP2017520569A5
JP2017520569A5 JP2016575150A JP2016575150A JP2017520569A5 JP 2017520569 A5 JP2017520569 A5 JP 2017520569A5 JP 2016575150 A JP2016575150 A JP 2016575150A JP 2016575150 A JP2016575150 A JP 2016575150A JP 2017520569 A5 JP2017520569 A5 JP 2017520569A5
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JP
Japan
Prior art keywords
disease
syndrome
jnk inhibitor
eye
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016575150A
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English (en)
Japanese (ja)
Other versions
JP6843625B2 (ja
JP2017520569A (ja
Filing date
Publication date
Priority claimed from PCT/EP2013/001880 external-priority patent/WO2014206426A1/en
Priority claimed from PCT/EP2014/002723 external-priority patent/WO2015197097A1/en
Application filed filed Critical
Priority claimed from PCT/EP2015/001293 external-priority patent/WO2015197193A2/en
Publication of JP2017520569A publication Critical patent/JP2017520569A/ja
Publication of JP2017520569A5 publication Critical patent/JP2017520569A5/ja
Application granted granted Critical
Publication of JP6843625B2 publication Critical patent/JP6843625B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016575150A 2013-06-26 2015-06-26 様々な疾患の処置のためのjnk阻害剤分子の新規使用 Expired - Fee Related JP6843625B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PCT/EP2013/001880 WO2014206426A1 (en) 2013-06-26 2013-06-26 New use for jnk inhibitor molecules for treatment of various diseases
EPPCT/EP2014/001737 2014-06-26
PCT/EP2014/001737 WO2014206564A1 (en) 2013-06-26 2014-06-26 New use for jnk inhibitor molecules for treatment of various diseases
EPPCT/EP2014/002723 2014-10-08
PCT/EP2014/002723 WO2015197097A1 (en) 2014-06-26 2014-10-08 New use for jnk inhibitor molecules for treatment of various diseases
PCT/EP2015/001293 WO2015197193A2 (en) 2014-06-26 2015-06-26 New use for jnk inhibitor molecules for treatment of various diseases

Publications (3)

Publication Number Publication Date
JP2017520569A JP2017520569A (ja) 2017-07-27
JP2017520569A5 true JP2017520569A5 (cg-RX-API-DMAC7.html) 2018-07-26
JP6843625B2 JP6843625B2 (ja) 2021-03-17

Family

ID=48771388

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016522322A Pending JP2016523275A (ja) 2013-06-26 2014-06-26 多様な疾患を処置するためのjnk阻害剤分子の新規な用途
JP2016575150A Expired - Fee Related JP6843625B2 (ja) 2013-06-26 2015-06-26 様々な疾患の処置のためのjnk阻害剤分子の新規使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016522322A Pending JP2016523275A (ja) 2013-06-26 2014-06-26 多様な疾患を処置するためのjnk阻害剤分子の新規な用途

Country Status (4)

Country Link
US (3) US20160115200A1 (cg-RX-API-DMAC7.html)
EP (1) EP3013853A1 (cg-RX-API-DMAC7.html)
JP (2) JP2016523275A (cg-RX-API-DMAC7.html)
WO (2) WO2014206426A1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
AU2010362444B2 (en) 2010-10-14 2015-08-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2016055160A2 (en) * 2014-10-08 2016-04-14 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
AU2014301631A1 (en) 2013-06-26 2015-08-27 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases
WO2014206426A1 (en) * 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
ES2949982T3 (es) * 2014-06-26 2023-10-04 Xigen Inflammation Ltd Inhibidores peptídicos permeables en células de la ruta de transducción de señales de JNK para el tratamiento de la cistitis
WO2015200768A2 (en) * 2014-06-26 2015-12-30 Auris Medical Ag Pharmacologic treatments of menière's disease
JP2025069480A (ja) * 2022-03-25 2025-05-01 メスキュージェナシス株式会社 ジンジパインに対して親和性及び/又は阻害能を有するペプチド及びその使用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674980A (en) 1989-12-21 1997-10-07 Biogen Inc Fusion protein comprising tat-derived transport moiety
US5804604A (en) 1989-12-21 1998-09-08 Biogen, Inc. Tat-derived transport polypeptides and fusion proteins
BR9610058A (pt) 1995-07-28 1999-07-27 Marie Curie Cancer Care Uso de vp22 ou uma porção ativa fragmento ou homólogo do mesmo proteína de transporte ácido nucleíco vetor de expressão célula hospedeira de mamíferos ou microbiana e processos para transportar uma proteína ou peptídeo desejado para uma população de marcaç o de células e para transportar uma molécula desejada em uma população de células
US6043083A (en) 1997-04-28 2000-03-28 Davis; Roger J. Inhibitors of the JNK signal transduction pathway and methods of use
EP1075271A4 (en) * 1998-04-17 2002-09-25 Univ Maryland METHOD FOR TREATING INTERSTITIAL CYSTITIS USING A GROWTH FACTOR LIKE THE EPIDERMAL RECOMBINANT GROWTH FACTOR ATTACHING TO HEPARIN (HB-EGF)
US20030108539A1 (en) * 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
MXPA05005101A (es) * 2002-11-15 2005-09-08 Sangstat Medical Corp Peptidos de citomodulacion para el tratamiento de cistitis intersticial.
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
JP2009538882A (ja) * 2006-06-02 2009-11-12 メルク セローノ ソシエテ アノニム 皮膚疾患の治療のためのjnk阻害物質
WO2009143865A1 (en) * 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
EA201171188A1 (ru) 2009-03-30 2012-05-30 Сантен Фармасьютикал Ко., Лтд. Профилактическое или терапевтическое средство против болезни сетчатки и способ профилактики или лечения болезни сетчатки с использованием jnk (c-jun-аминоконцевая киназа)-ингибиторного пептида, а также применение указанного пептида
WO2010151638A1 (en) 2009-06-25 2010-12-29 Medical College Of Georgia Research Institute, Inc. Jnk inhibitors for use in treating spinal muscular atrophy
GB2478599B (en) * 2010-03-12 2014-07-16 Dyson Technology Ltd A vacuum cleaning arrangement
WO2011160653A1 (en) * 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
AU2010362444B2 (en) * 2010-10-14 2015-08-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
MX2014006399A (es) * 2011-11-30 2015-04-10 Xigen Inflammation Ltd Uso de inhibidores de peptidos con celulas permeables de la via para transduccion de señal de jnk para el tratamiento de la queratoconjuntivitis seca.
WO2013091670A1 (en) * 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
AU2014301631A1 (en) * 2013-06-26 2015-08-27 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases
WO2014206426A1 (en) * 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases

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