JP2017519501A5 - - Google Patents

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Publication number
JP2017519501A5
JP2017519501A5 JP2016573833A JP2016573833A JP2017519501A5 JP 2017519501 A5 JP2017519501 A5 JP 2017519501A5 JP 2016573833 A JP2016573833 A JP 2016573833A JP 2016573833 A JP2016573833 A JP 2016573833A JP 2017519501 A5 JP2017519501 A5 JP 2017519501A5
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JP
Japan
Prior art keywords
antibody
axl
domain
seq
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016573833A
Other languages
English (en)
Japanese (ja)
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JP2017519501A (ja
JP6787795B2 (ja
Filing date
Publication date
Priority claimed from GBGB1410826.0A external-priority patent/GB201410826D0/en
Application filed filed Critical
Publication of JP2017519501A publication Critical patent/JP2017519501A/ja
Publication of JP2017519501A5 publication Critical patent/JP2017519501A5/ja
Application granted granted Critical
Publication of JP6787795B2 publication Critical patent/JP6787795B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016573833A 2014-06-18 2015-06-18 抗Axl抗体 Active JP6787795B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1410826.0A GB201410826D0 (en) 2014-06-18 2014-06-18 Anti-axl antibodies
GB1410826.0 2014-06-18
PCT/EP2015/063700 WO2015193428A1 (en) 2014-06-18 2015-06-18 Anti-axl antibodies

Publications (3)

Publication Number Publication Date
JP2017519501A JP2017519501A (ja) 2017-07-20
JP2017519501A5 true JP2017519501A5 (https=) 2018-05-10
JP6787795B2 JP6787795B2 (ja) 2020-11-18

Family

ID=51266761

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016573833A Active JP6787795B2 (ja) 2014-06-18 2015-06-18 抗Axl抗体

Country Status (15)

Country Link
US (3) US9975954B2 (https=)
EP (1) EP3157559B1 (https=)
JP (1) JP6787795B2 (https=)
KR (1) KR102453226B1 (https=)
CN (2) CN113563471B (https=)
AU (1) AU2015276153B2 (https=)
CA (1) CA2952296A1 (https=)
DK (1) DK3157559T3 (https=)
GB (1) GB201410826D0 (https=)
HR (1) HRP20201091T1 (https=)
HU (1) HUE049755T2 (https=)
LT (1) LT3157559T (https=)
MX (1) MX388222B (https=)
SI (1) SI3157559T1 (https=)
WO (1) WO2015193428A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201410825D0 (en) 2014-06-18 2014-07-30 Bergenbio As Anti-axl antibodies
GB201410826D0 (en) * 2014-06-18 2014-07-30 Bergenbio As Anti-axl antibodies
JP6864953B2 (ja) * 2014-12-09 2021-04-28 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Axlに対するヒトモノクローナル抗体
AU2015366213B2 (en) * 2014-12-18 2021-10-07 Bergenbio Asa Anti-Axl antagonistic antibodies
GB201506411D0 (en) 2015-04-15 2015-05-27 Bergenbio As Humanized anti-axl antibodies
GB201509338D0 (en) 2015-05-29 2015-07-15 Bergenbio As Combination therapy
GB201610902D0 (en) 2016-06-22 2016-08-03 Bergen Teknologioverforing As And Bergenbio As Anti-Axl Antagonistic Antibodies
RS61795B1 (sr) * 2017-02-08 2021-06-30 Adc Therapeutics Sa Konjugati pirolobenzodiazepin antitela
US20210215697A1 (en) * 2018-05-14 2021-07-15 Bergenbio Asa Serum Biomarkers
CN110540592B (zh) * 2018-05-29 2022-08-09 杭州尚健生物技术有限公司 结合axl蛋白的抗体及其应用
EP3946453A4 (en) * 2019-03-29 2022-12-07 Celldex Therapeutics, Inc. ANTI-AXL ANTIBODIES AND THEIR METHODS OF USE
GB201912059D0 (en) 2019-08-22 2019-10-09 Bergenbio As Combaination therapy of a patient subgroup
CN113045664B (zh) * 2019-11-28 2023-05-12 尚健单抗(北京)生物技术有限公司 一种分离的结合抗原axl的蛋白及其用途
WO2021154156A1 (en) * 2020-01-31 2021-08-05 Agency For Science, Technology And Research Anti-axl antibody and uses thereof
US11807688B2 (en) * 2020-02-28 2023-11-07 Les Laboratoires Servier Anti-AXL antibodies and compositions
GB202004189D0 (en) 2020-03-23 2020-05-06 Bergenbio As Combination therapy
EP4132652A1 (en) 2020-04-08 2023-02-15 BerGenBio ASA Axl inhibitors for antiviral therapy
GB202006072D0 (en) 2020-04-24 2020-06-10 Bergenbio Asa Method of selecting patients for treatment with cmbination therapy
EP4286406A4 (en) 2021-01-29 2025-07-23 Illimis Therapeutics Inc FUSION MOLECULE WITH NON-INFLAMMATORY PHAGOCYTOSIS-INDUCING ACTIVITY
GB202104037D0 (en) 2021-03-23 2021-05-05 Bergenbio Asa Combination therapy
IL289525B2 (en) * 2021-12-30 2023-03-01 B G Negev Technologies And Applications Ltd At Ben Gurion Univ Conjugated antibodies for cancer treatment
CN116348497B (zh) * 2023-01-05 2023-11-17 浙江时迈药业有限公司 针对axl的抗体及其用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884879B1 (en) * 1997-04-07 2005-04-26 Genentech, Inc. Anti-VEGF antibodies
CL2007002668A1 (es) * 2006-09-20 2008-05-09 Amgen Inc Proteina de union a antigeno que se une al receptor de glucagon humano; acido nucleico que la codifica; metodo de produccion; composicion farmaceutica que la comprende; y su uso para tratar o prevenir la diabetes tipo 2.
JP5769969B2 (ja) * 2007-11-12 2015-08-26 ユー3・ファーマ・ゲーエムベーハー Axl抗体
AU2008321835B2 (en) 2007-11-15 2014-11-20 Chugai Seiyaku Kabushiki Kaisha Monoclonal antibody capable of binding to anexelekto, and use thereof
EP2198884A1 (en) * 2008-12-18 2010-06-23 Centre National de la Recherche Scientifique (CNRS) Monoclonal antibodies directed against LG4-5 domain of alpha3 chain of human laminin-5
EP2270053A1 (en) * 2009-05-11 2011-01-05 U3 Pharma GmbH Humanized AXL antibodies
KR20120024763A (ko) 2009-05-15 2012-03-14 추가이 세이야쿠 가부시키가이샤 항axl 항체
TW201106972A (en) * 2009-07-27 2011-03-01 Genentech Inc Combination treatments
RU2577986C2 (ru) * 2010-06-18 2016-03-20 Дженентек, Инк. Антитела против axl и способы их применения
ES2677367T3 (es) 2011-06-22 2018-08-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Anticuerpos anti-Axl y usos de los mismos
CA2839508A1 (en) * 2011-06-22 2012-12-27 Inserm (Institut National De La Sante Et De La Recherche Medicale) Anti-axl antibodies and uses thereof
EP2589609A1 (en) 2011-11-03 2013-05-08 Pierre Fabre Medicament Antigen binding protein and its use as addressing product for the treatment of cancer
GB201410825D0 (en) 2014-06-18 2014-07-30 Bergenbio As Anti-axl antibodies
GB201410826D0 (en) * 2014-06-18 2014-07-30 Bergenbio As Anti-axl antibodies
AU2015366213B2 (en) * 2014-12-18 2021-10-07 Bergenbio Asa Anti-Axl antagonistic antibodies
GB201506411D0 (en) * 2015-04-15 2015-05-27 Bergenbio As Humanized anti-axl antibodies
WO2018193102A1 (en) * 2017-04-20 2018-10-25 Adc Therapeutics Sa Combination therapy with an anti-axl antibody-drug conjugate

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