JP2017517261A5 - - Google Patents
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- Publication number
- JP2017517261A5 JP2017517261A5 JP2016569420A JP2016569420A JP2017517261A5 JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5 JP 2016569420 A JP2016569420 A JP 2016569420A JP 2016569420 A JP2016569420 A JP 2016569420A JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5
- Authority
- JP
- Japan
- Prior art keywords
- deoxyuridine
- aptamer
- protein
- seq
- methyluridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462005300P | 2014-05-30 | 2014-05-30 | |
| US62/005,300 | 2014-05-30 | ||
| PCT/US2015/033355 WO2015184372A1 (en) | 2014-05-30 | 2015-05-29 | Nucleic acid compounds for binding to complement component 3 protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017517261A JP2017517261A (ja) | 2017-06-29 |
| JP2017517261A5 true JP2017517261A5 (https=) | 2019-03-14 |
| JP6824041B2 JP6824041B2 (ja) | 2021-02-03 |
Family
ID=53398218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016569420A Expired - Fee Related JP6824041B2 (ja) | 2014-05-30 | 2015-05-29 | ３つのタンパク質を補体成分に結合するための核酸化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11466275B2 (https=) |
| EP (1) | EP3149173B1 (https=) |
| JP (1) | JP6824041B2 (https=) |
| CN (2) | CN106459979B (https=) |
| CA (1) | CA2949246C (https=) |
| ES (1) | ES2664179T3 (https=) |
| NO (1) | NO2718257T3 (https=) |
| WO (1) | WO2015184372A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI770036B (zh) | 2016-07-01 | 2022-07-11 | 美商私募蛋白質體操作有限公司 | 包含經修飾核苷之寡核苷酸 |
| EP4047004B1 (en) * | 2019-10-18 | 2024-03-06 | FUJIFILM Wako Pure Chemical Corporation | Phosphoramidite activator |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6140490A (en) * | 1996-02-01 | 2000-10-31 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands of complement system proteins |
| US6395888B1 (en) | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| WO1997042317A1 (en) * | 1996-05-07 | 1997-11-13 | T Cell Sciences, Inc. | APTAMERS FOR COMPLEMENT PROTEIN C3b |
| US20020082227A1 (en) * | 1999-09-30 | 2002-06-27 | Scott Henry | Use of oligonucleotides for inhibition of complement activation |
| US20030219801A1 (en) * | 2002-03-06 | 2003-11-27 | Affymetrix, Inc. | Aptamer base technique for ligand identification |
| WO2007084886A2 (en) * | 2006-01-17 | 2007-07-26 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| US8975026B2 (en) * | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US7947447B2 (en) * | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US8927509B2 (en) * | 2008-05-20 | 2015-01-06 | The Research Foundation Of State University Of New York | Aptamer modulators of complement protein C3 and biologically active proteolytic products thereof |
| EP3345915B1 (en) * | 2010-04-12 | 2021-11-24 | Somalogic, Inc. | 5-position modified pyrimidines and their use |
| AU2012225273B2 (en) * | 2011-03-10 | 2016-10-13 | Somalogic, Inc. | Aptamers for Clostridium difficile diagnostics |
| US9243060B2 (en) * | 2012-04-03 | 2016-01-26 | Novelmed Therapeutics, Inc. | Humanized anti-factor C3b antibodies and uses thereof |
| SG10201913948PA (en) * | 2016-08-24 | 2020-03-30 | Sangamo Therapeutics Inc | Engineered target specific nucleases |
| CN118955717A (zh) * | 2019-07-11 | 2024-11-15 | 纪念斯隆凯特琳癌症中心 | Dll3靶向抗体及其用途 |
-
2012
- 2012-06-08 NO NO12796164A patent/NO2718257T3/no unknown
-
2015
- 2015-05-29 JP JP2016569420A patent/JP6824041B2/ja not_active Expired - Fee Related
- 2015-05-29 CN CN201580028344.6A patent/CN106459979B/zh not_active Expired - Fee Related
- 2015-05-29 EP EP15729302.8A patent/EP3149173B1/en not_active Not-in-force
- 2015-05-29 US US15/311,714 patent/US11466275B2/en active Active
- 2015-05-29 CA CA2949246A patent/CA2949246C/en active Active
- 2015-05-29 ES ES15729302.8T patent/ES2664179T3/es active Active
- 2015-05-29 WO PCT/US2015/033355 patent/WO2015184372A1/en not_active Ceased
- 2015-05-29 CN CN201910922493.7A patent/CN110643610A/zh active Pending
-
2022
- 2022-08-29 US US17/822,854 patent/US20230093170A1/en not_active Abandoned
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