JP2017516862A5 - - Google Patents

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Publication number

JP2017516862A5

JP2017516862A5 JP2017515034A JP2017515034A JP2017516862A5 JP 2017516862 A5 JP2017516862 A5 JP 2017516862A5 JP 2017515034 A JP2017515034 A JP 2017515034A JP 2017515034 A JP2017515034 A JP 2017515034A JP 2017516862 A5 JP2017516862 A5 JP 2017516862A5

Authority

JP

Japan

Prior art keywords

haloalkyl

item

compound according

alkyl

compound

Prior art date

2015-05-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

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• 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 36
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• 108010080146 androgen receptors Proteins 0.000 claims description 16
• 125000000217 alkyl group Chemical group 0.000 claims description 15
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• 239000008194 pharmaceutical composition Substances 0.000 claims description 11
• -1 t-butoxy Chemical group 0.000 claims description 10
• 229940124597 therapeutic agent Drugs 0.000 claims description 10
• 125000003545 alkoxy group Chemical group 0.000 claims description 9
• 230000000694 effects Effects 0.000 claims description 8
• 239000011203 carbon fibre reinforced carbon Substances 0.000 claims description 6
• 150000003839 salts Chemical class 0.000 claims description 5
• 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 4
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• 239000003937 drug carrier Substances 0.000 claims description 4
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 4
• CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 claims description 2
• 125000001188 haloalkyl group Chemical group 0.000 claims description 2
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• 229910052760 oxygen Inorganic materials 0.000 claims description 2
• 229910052717 sulfur Inorganic materials 0.000 claims description 2
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• MKXKFYHWDHIYRV-UHFFFAOYSA-N flutamide Chemical compound CC(C)C(=O)NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1 MKXKFYHWDHIYRV-UHFFFAOYSA-N 0.000 description 2
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