JP2017513876A - Cosmetic composition containing mint vinegar as an active ingredient - Google Patents

Abstract

The present invention relates to a cosmetic composition containing mint vinegar as an active ingredient. [Selection] Figure 2

Description

  The present invention relates to a cosmetic composition containing mint vinegar as an active ingredient.

  This application claims the benefit of the filing date of Korean Patent Application No. 10-2014-0049216 filed with the Korean Patent Office on April 24, 2014, the entire text of which is included herein by reference.

  A pore is an entrance where hair grows, and unlike a sweat hole, the diameter is about 0.02 to 0.05 mm, and it is known that there are about 20,000 on the face alone. Sebum flows out to the skin surface through the pores. At puberty, many hormones are secreted, the sebaceous glands become larger, and more sebum is secreted, resulting in larger pores in the sebum secretion pathway. Also, during pregnancy, when stressed, and when the weather is warm, sebum secretion increases and pores become larger.

  In the late twenties, aging of the skin begins, and collagen, elastin, etc. that supported the pore walls are decomposed or altered, so that the elasticity of the skin is lowered and the pores droop or spread. As pores grow larger, waste products and bacteria become more permeated, causing various skin diseases such as acne.

  Cosmetic raw materials have various problems, such as most of the effects are insufficient or side effects such as skin irritation are induced. Therefore, research on raw materials having an effect of promoting skin regeneration without inducing side effects on the skin has been actively conducted. In particular, recently, fermentation technology using microorganisms has been developed, and in many cases, substances derived from plants and other natural raw materials are used as physiologically active substances, secondary metabolites obtained through fermentation technology. is increasing. This component is known to have various physiological activities, and has attracted attention as a new raw material for highly functional cosmetics. By using this technology, it is possible to economically produce a highly functional active substance that is a naturally occurring substance, but whose amount is very small or difficult to apply to the skin. In this respect, it is expected that new components that have not been used so far can be developed and applied. In particular, although customers' demand for functional cosmetics is increasing, the use of fermentation technology that can produce innumerable new functional ingredients in that new functional materials and related technologies are not sufficiently developed. Cosmetics will gain great popularity in the field of various skin benefits, especially anti-aging benefits.

  Provided is a cosmetic composition that maximizes the effectiveness of mint, which is useful for skin activation and skin health, not only to remove waste products, but also to manage pores.

  Therefore, in order to maximize the efficacy of mint, the present inventor found skin pores and a sebum cleansing effect when mint was used in a cosmetic composition by fermentation with acetic acid, and the present invention was completed.

  In order to achieve the above-described object, the present invention provides a cosmetic composition containing mint vinegar.

  Since the cosmetic composition according to the present invention contains mint vinegar obtained by fermenting acetic acid bacteria and mint, which are effective organic acid bacteria, blood purification, antibacterial, anti-aging, metabolism In addition to having an effect of promoting aging, it is possible to remove metabolic waste products and manage pores.

  Also, because of its excellent astringent action, it is good for skin with large pores or reduced elasticity, and mint, which is an effective ingredient for pruritus, inflammation and acne, is fermented with acetic acid to widen pores. It has a contraction effect that regains the elasticity of dripping pores, and has a disinfection and sedative effect.

FIG. 1 shows changes in pore size due to application of Dosage Form 1 to the skin of a subject based on Test Example 1, and the Dosage Form Example 1 is applied to the skin of the test person. It is the previous photo. FIG. 2 shows changes in the pore size due to the application of dosage form example 1 to the skin of the subject based on Test Example 1. The dosage form example 1 was applied to the skin of the subject. It is a later photo. FIG. 3 shows the change in pore size by applying Comparative Dosage Form Example 1 to the skin of the subject based on Test Example 1. The Comparative Dosage Form Example 1 is applied to the skin of the test subject. It is the photograph before apply | coating. FIG. 4 shows the change in pore size by applying Comparative Dosage Form 1 to the skin of the test subject based on Test Example 1, and the Comparative Dosage Form Example 1 is applied to the skin of the test subject. It is the photograph after apply | coating. FIG. 5 shows the change in pore size by applying Comparative Dosage Form 2 to the skin of the test subject based on Test Example 1, and the Comparative Dosage Form Example 2 is applied to the skin of the test subject. It is the photograph before apply | coating. FIG. 6 shows the change in pore size by applying Comparative Dosage Form 2 to the skin of the subject based on Test Example 1. The Comparative Dosage Form Example 2 is applied to the skin of the subject. It is the photograph after apply | coating. FIG. 7 shows the change in the number of sebum due to the application of Dosage Form 1 to the skin of the subject based on Test Example 1 before the dosage form 1 is applied to the skin of the test person. It is a photograph. FIG. 8 shows the change in the number of sebum due to the application of the dosage form example 1 to the skin of the subject based on the test example 1, and is a photograph after the dosage form example 1 is applied to the skin. FIG. 9 shows the change in the number of sebum due to the application of Comparative Dosage Form 1 to the skin of the examinee based on Test Example 1, and the Comparative Dosage Form Example 1 is applied to the skin of the test person. It is the previous photo. FIG. 10 shows the change in the number of sebum due to the application of the comparative dosage form 1 to the skin of the test subject based on the test example 1. The comparative dosage form example 1 was applied to the skin of the test subject. It is a later photo. FIG. 11 shows the change in the number of sebum due to the application of the comparative dosage form example 2 to the skin of the test subject based on the test example 1, and the comparative dosage form example 2 is applied to the skin of the test subject. It is the previous photo. FIG. 12 shows the change in the number of sebum by applying the comparative dosage form example 2 to the skin of the test subject based on the test example 1, and the comparative dosage form example 1 was applied to the skin of the test subject. It is a later photo.

  Mint (scientific name: Mentha piperita) is a perennial plant belonging to the family Lamiaceae, and has been used for food and medicine for a long time in both the East and West. It is known that it has various effects useful for skin health as well as various pharmacological actions. The essential oil content in the main component of mint was 2% to 3%, 4% to 6% for petals, and 0.3% for stems. 70% to 90% of the main component of such mint essential oil is menthol, and physiological components such as I-menthol, isomenthol, pinene, camphene and limonene are useful for various skin activation and skin health. It is known. In addition, vitamin C, carotene, phytol, betaine, etc. help to relieve skin fatigue and maintain healthy and brilliant skin.

  In one embodiment of the present invention, the mint vinegar is obtained by subjecting mint to acetic acid fermentation. Acetic acid fermentation is an aerobic fermentation in which alcohol is oxidized by the action of acetic acid bacteria to produce acetic acid. Acetobacter aceti oxidizes ethanol to produce acetic acid. Acetic acid fermentation may have a log phase of about 12 hours to 48 hours, with acid production increasing rapidly from 12 to 24 hours. In acetic acid fermentation, acetic acid producing ability and sugar resolving power were most stable in a culture temperature of 30 ° C., a medium supplemented with 4% ethanol, pH 6.5-7.

  Vinegar contains about 60 or more organic acids such as acetic acid, citric acid, amino acids, and succinic acid, and serves as a promoter that helps the body absorb various nutrients such as vitamins and minerals. In particular, it acts as a blood purification agent that purifies our meat and blood, promotes the metabolism of the human body and raises the natural healing power to the highest level, suppresses spots and freckles, and is the main cause of skin aging Inhibits lipid peroxides and helps to activate cell metabolism. In addition, it breaks down the lactic acid in the skin and muscles and acts to smooth the blood flow.

  Acetic acid is superior to other organic acids in blood purification, antibacterial properties, anti-aging, and metabolism promoting ability.

  In one embodiment of the present invention, the mint vinegar is produced by a culture method in which microorganisms are propagated from the surface of a liquid.

  Mint vinegar produced by the above-mentioned culture method is characterized by the fact that the microbial membrane is always in contact with air, and that dissolved oxygen dissolved from the liquid surface can be used well, and only the effects of the components of existing mint are present. In addition, it has the advantage that it can be obtained through acetic acid fermentation.

  In one embodiment of the present invention, the mint is an extract of any of mint leaves and stems, or a combination thereof.

  Mint leaves and stems have excellent bactericidal and anthelmintic effects, prevent bad breath and are used as toothpaste. If the leaves are crushed and used as a poultice, it is effective in treating skin irritation and bruises, and also in treating dermatitis and pruritus. While calming the stimulated skin from large or small wounds, it reduces itching and abnormal reactions, gives the skin vitality and stress relief, helps with light astringency and elasticity maintenance. Mint leaves contain 2% to 3% essential oil, and mint stems contain up to 1% essential oil. Menthol, which accounts for about 70% of the essential oil, is a component that produces a scent and medicinal properties peculiar to mint. Mint's unique aroma can be obtained from menthol and mentone. In the case of menthol, it has the property of converging, has the effect of pulling the dripping skin and shrinking the pores, and gives the skin a good effect. In addition, the mucous membranes and blood vessels of the skin contract to give a refreshing feeling to the local site. Menthol, which has a unique refreshing scent, is a colorless needle-like crystal that is almost insoluble in water, but well soluble in ethanol and chloroform. It is obtained from mint leaves and stems. If a large amount is put in the mouth, it feels like a stabbed tongue, but a small amount gives a refreshing feeling.

  In one embodiment of the present invention, the cosmetic composition contains alpha-hydroxy acid (AHA). Alpha hydroxy acid is a compound in which an alcohol group or hydroxy group is added to the carbon at the α-position of carboxylic acid, and lowers the ion binding energy of keratinocytes to remove excess keratinocytes or form new cells. Promotes and shortens the cycle of the keratinization process where the skin ages and droops, promotes the activity of skin cells and improves the skin. It also promotes the production of collagen and elastin by fibroblasts, making the skin elastic and soft, and promotes the production of mucopolysaccharide, an important extracellular matrix component of the dermis, to moisturize the skin. To improve.

  In one embodiment of the present invention, the content of the mint vinegar is 0.001% by weight to 20% by weight with respect to the total weight of the cosmetic composition. When the mint vinegar is less than 0.001% by weight, the sufficient effect intended by the present invention cannot be expected. When the mint vinegar exceeds 20% by weight, the menthol component contained in the mint vinegar temporarily A feeling of irritation may appear.

  In one embodiment of the present invention, the cosmetic composition is for pore reduction. Mint vinegar fermented with mint in acetic acid has a constrictive effect that maximizes the astringent effect of mint, prevents the pores from becoming wider, and restores the elasticity of dripping pores.

  In one embodiment of the present invention, the cosmetic composition is for sebum regulation. Mint vinegar fermented with mint in acetic acid has the effect of promoting skin blood purification, antibacterial activity, anti-aging, and metabolism, and at the same time not only removes waste products but also enables management of pores.

  The cosmetic composition according to the present invention is not particularly limited in its dosage form. For example, it is formulated into a soft lotion, nutritional lotion, essence, massage cream, nutritional cream, pack, gel, or skin adhesive type cosmetic. can do.

  Hereinafter, with reference to a test example and a dosage form example, the structure and effect of this invention are demonstrated more concretely. However, it will be understood that these test examples and dosage form examples are provided for purposes of illustration and are not intended to limit the scope of the invention.

<Production example>
2 to 3 g of acetic acid bacteria (manufactured by Merck, strain name: Acetobacter acetic KCTC1010) in a medium (mannitol agar medium / YPM / Medium), 100 g of mint material prepared in advance (75 to 80% by weight of mint leaves, 20 to 25% by weight of stems) %) Was added and inoculated, and after 48 hours of fermentation at a temperature of about 26 ° C., an extraction solution (mixed solution of 20 mL of purified water and 50 mL of ethanol) was added to the obtained fermented product, and room temperature (25 For 1 hour. After removing ethanol and materials by primary filtration [ultrafiltration (pore size = 50 μm)], only pure fermentation supernatant was taken. The supernatant was centrifuged again (ultra-high speed centrifuge, 400 rpm) and subjected to secondary filtration [ultrafiltration (pore size = 10 μm)], and then 100 mL of a sterilized solution [based on the total volume of the solution] 70% to 94% purified water, 5% to 10% butylene glycol, 0.01% to 0.05% disodium EDTA and 0.4% to 1.0% preservative (phenoxyethanol)] After 10 to 15 minutes of sterilization step, 100 ml of mint vinegar was finally produced.

  On the other hand, a mint extract was prepared to contrast the efficacy of mint vinegar. This extract consists of 100 g of mint material (75 to 80% by weight of mint leaf, 20 to 25% by weight of stem) and 100 mL of extraction solution (70% to 95% purified water based on the total volume of the solution, 5% to 30% butylene glycol) ) And extracted at room temperature to produce 100 mL of mint extract.

<Examples and Comparative Examples>
As a cosmetic composition containing mint vinegar as an active ingredient, a cosmetic composition of Formulation Example 1 having the composition shown in Table 1 below was produced by the following method. Moreover, in order to compare with the dosage form example 1 within the scope of the present invention, the cosmetic composition of the comparative dosage form example 1 having the composition of Table 1 below as a cosmetic composition containing a mint extract as an active ingredient. The product was prepared by the following method. (Unit:% by weight)

  The solubilized phase was added to the aqueous phase that was transparently dissolved at room temperature, and after uniformly dissolving, mint vinegar was added and dissolved uniformly to produce the cosmetic composition of Formulation Example 1. In addition, Comparative Dosage Form Example 1 was prepared by adding a solubilized phase to an aqueous phase that was transparently dissolved at room temperature, and uniformly dissolving the mint extract without adding mint vinegar. . Comparative dosage form example 2 was prepared without adding the mint vinegar and mint extract after adding the solubilized phase to the aqueous phase transparently dissolved at room temperature and dissolving it uniformly.

<Test Example 1> Evaluation of skin pore and sebum improvement efficacy In order to confirm the skin elasticity recovery effect, pore reduction effect and sebum regulation effect of the above-mentioned formulation example 1, comparative formulation example 1 and comparative formulation example 2, Measurements were made on women in their teens to thirties. After each dosage form of Dosage Form Example 1, Comparative Dosage Form Example 1 and Comparative Dosage Form Example 2 was uniformly applied to the entire face in each group, the pore reduction effect and sebum regulating effect were evaluated.

  In this test, the test product was used once under constant temperature and humidity conditions for subjects suitable for the test purpose. A female subject who suffers from pores was used as a target, and the sample was used in a general usage method, and the pore management efficacy immediately after use of the sample was evaluated.

After washing the face, an appropriate amount (2 mg / cm ² ) of the sample was taken and applied evenly while gently rubbing the entire face by hand. Subjects during the test period were evaluated before and immediately after using the sample. The subject visited the measurement time point, and immediately after washing the face, kept at a constant temperature and humidity condition (22 ± 2 ° C., 40 ± 5RH%) for 15 minutes or more, and then used the sample at the measurement time point shown in Table 2 below. And the evaluation was carried out.

  Measurements of pore size, sebum size and number of skin samples applied to the skin of this test example were performed using a measuring equipment skin touch developed by Amore Pacific Co., Ltd. Skin touch measures skin oil, moisture, and elasticity with an integrated sensor, and the measurement results are displayed on an external LCD display window. The size of pores and the size and number of sebum at the time of skin application of the sample were evaluated by measuring the test site using the skin touch before use of the sample and after 1 week and 2 weeks of use of the sample.

  As a result, in the case of facial pores, the number of sebum, the size of sebum (unit: AU), and the size of the pores immediately after use compared to the sample containing mint vinegar as an active ingredient before use. As shown in Table 3 below, the result of statistically significant decrease in (unit: AU) was revealed.

  From the results shown in Table 3 and FIGS. 1 to 12, the results of Comparative Example 1 and Comparative Example 2 show that the pore shrinkage, the reduction in the number of sebum, and the improvement in the number of pores are as follows. It was confirmed that it was superior to

Claims (8)

  A cosmetic composition containing mint vinegar as an active ingredient.   The cosmetic composition according to claim 1, wherein the mint vinegar is obtained by acetic acid fermentation of a mint extract.   The cosmetic composition according to claim 2, wherein the acetic acid fermentation is performed using Acetobacter aceti.   The cosmetic composition according to claim 2, wherein the mint extract is an extract of any one of mint leaves and stems, or a combination thereof.   The cosmetic composition according to claim 1, wherein the cosmetic composition contains an alpha hydroxy acid.   The cosmetic composition according to claim 1, wherein a content of the mint vinegar is 0.001% by weight to 20% by weight with respect to a total weight of the composition.   The cosmetic composition according to claim 1, wherein the cosmetic composition is for pore reduction. The cosmetic composition according to claim 1, wherein the cosmetic composition is for sebum control.

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