CN106232101A - The cosmetic composition of Herba Menthae vinegar is contained as effective ingredient - Google Patents
The cosmetic composition of Herba Menthae vinegar is contained as effective ingredient Download PDFInfo
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- CN106232101A CN106232101A CN201580021097.7A CN201580021097A CN106232101A CN 106232101 A CN106232101 A CN 106232101A CN 201580021097 A CN201580021097 A CN 201580021097A CN 106232101 A CN106232101 A CN 106232101A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Tropical Medicine & Parasitology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the cosmetic composition containing Herba Menthae vinegar as effective ingredient.
Description
Technical field
The present invention relates to the cosmetic composition containing Herba Menthae vinegar as effective ingredient.
The application advocates the korean patent application 10-2014-proposed on April 24th, 2014 in Korea S's special permission Room
The interests of the applying date of No. 0049216, its content is entirely included in this specification.
Background technology
It is known that pore is the growth mouth of hair, different from sweat gland, a diameter of 0.02~0.05mm, only just have in face
About more than 20,000.By this pore, sebum flows out skin surface.To adolescence, will secrete hormones, sebaceous gland will become
Greatly, secreting a lot of sebum, therefore the pore as sebum secretion passage will become big.During it addition, adolescence or pressure are big, or
When weather warms up, sebum secretion also can be vigorous, and pore will become big.
During 20 year old latter half, skin starts aging, can divide for supporting collagen protein or the elastin laminin etc. of pore wall
Solving or rotten, so skin elasticity will reduce, skin will be dried, slack and undisciplined, and pore will relax or expand.Patulous follicular orifice
Time, refuse and antibacterial are easily accessible pore, will cause the various dermatosiss such as acne.
There are the various problems of the side effect such as low effort or induction stimulation skin in cosmetic material major part.To this end, close
In not inducing skin side-effects and having the raw material of skin regeneration enhancement effect, its research is active to be carried out.Particularly, recently
Along with the development of the fermentation technique utilizing microorganism, often have and secondary metabolic product is utilized as biological active substances, should
Secondary metabolic product is to be obtained by fermentation technique by the material deriving from plant or other natural materials.These compositions known
There is multiple physiologically active, so the new raw material as high functionality cosmetics gets most of the attention.Although high functional activity material is
Naturally occurring material, but its amount is considerably less, or it is difficult to use in skin, but when utilizing above-mentioned technology, can be raw with economy
Produce high functionality active substance, in this viewpoint, be expected to develop and apply the new component the most not used.Especially
It is, although very big to the demand of the client of functional cosmetics, but new functionalized material or correlation technique are underdeveloped,
In this viewpoint, utilize the cosmetics of the fermentation technique of available a lot of new functionalized compositions, in various skin usefulness, particularly exist
Aging resistance usefulness aspect causes people's extensive concern.
Summary of the invention
It is an object of the present invention to provide a kind of cosmetic composition, this cosmetic composition be make to contribute to skin activityization and
The usefulness maximization of the Herba Menthae of skin health, not only can remove refuse, and can manage pore.
To this end, the present inventor is in order to make the usefulness of Herba Menthae maximize, Herba Menthae is carried out acetic fermentation and is used for cosmetics group
During compound, find that there is the pore of cleaning skin and the effect of sebum, thus complete the present invention.
In order to achieve the above object, the present invention provides the cosmetic composition containing Herba Menthae vinegar.
The cosmetic composition that the present invention relates to contains Herba Menthae vinegar as effective ingredient, and this Herba Menthae vinegar is to utilize Herba Menthae to have
In the organic acid of effect, a kind of acetobacter carries out fermenting, and this cosmetic composition has the blood purification of skin, antibacterial, anti-
Effect the most aging, that enhance metabolism, can also remove refuse and management pore simultaneously.The astriction of Herba Menthae is excellent, from
And big to pore or the elastic skin reduced effectively, to the most effective composition of pruritus and inflammation, acne, this Herba Menthae is carried out vinegar
Acid fermentation, prevents patulous follicular orifice, has the contractive effect that the pore making to relax recovers elastic, has sterilization and calming effect.
Accompanying drawing explanation
Fig. 1 represents the change in pore aperture when the dosage form example 1 of test example 1 being coated on the skin of testee, be by
Dosage form example 1 is coated in the photo before testee's skin.
Fig. 2 represents the change in pore aperture when the dosage form example 1 of test example 1 being coated on the skin of testee, be by
Dosage form example 1 is coated in the photo after testee's skin.
Fig. 3 represents the change in pore aperture when the contrast dosage form example 1 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 1 is coated in the photo before testee's skin.
Fig. 4 represents the change in pore aperture when the contrast dosage form example 1 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 1 is coated in the photo after testee's skin.
Fig. 5 represents the change in pore aperture when the contrast dosage form example 2 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 2 is coated in the photo before testee's skin.
Fig. 6 represents the change in pore aperture when the contrast dosage form example 2 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 2 is coated in the photo after testee's skin.
Fig. 7 represents the change of sebum quantity when the dosage form example 1 of test example 1 being coated on the skin of testee, be by
Dosage form example 1 is coated in the photo before testee's skin.
Fig. 8 represents the change of sebum quantity when the dosage form example 1 of test example 1 being coated on the skin of testee, be by
Dosage form example 1 is coated in the photo after testee's skin.
Fig. 9 represents the change of sebum quantity when the contrast dosage form example 1 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 1 is coated in the photo before testee's skin.
Figure 10 represents the change of sebum quantity when the contrast dosage form example 1 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 1 is coated in the photo after testee's skin.
Figure 11 represents the change of sebum quantity when the contrast dosage form example 2 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 2 is coated in the photo before testee's skin.
Figure 12 represents the change of sebum quantity when the contrast dosage form example 2 of test example 1 being coated on the skin of testee,
It is that contrast dosage form example 1 is coated in the photo after testee's skin.
Detailed description of the invention
It is known that Herba Menthae (Mentha piperita) is the perennial herb of Labiatae, it is that thing ocean is used as a long time
Edible and medicinal natural plants, it, no less than multiple pharmacological effect, has the multi-effect contributing to skin health.People
Knowing, in the main component of Herba Menthae, the content of quintessence oil is 2% to 3%, and the essential oil content of floral leaf is 4% to 6%, and the quintessence oil of stem contains
Amount is 0.3%, shows high essential oil content, these Peppermint essential oil be mainly composed of menthol, containing 70% to 90%, I-Herba Menthae
The physiological compositions of alcohol, isomenthone, pinene, limonene, camphene etc. contributes to various skin activation and skin health.Additionally, dimension
Raw element C, carotene, phytol, glycine betaine etc. also contribute to eliminate feeling of fatigue and the skin of gloss of keeping fit of skin.
In an embodiment of the invention, Herba Menthae is utilized acetic fermentation by above-mentioned Herba Menthae vinegar.Acetic fermentation is
Carry out Oxidation of Alcohol by the effect of acetobacter, generate the aerobic fermentation of acetic acid, acetobacter (Acetobacter aceti) oxygen
Change ethanol, generate acetic acid (Acetic acid).The logarithmic (log) phase of acetic fermentation can be about 12 hours to 48 hours, the life of acid
One-tenth amount sharply increased in 12~24 hours.When the cultivation temperature of acetic fermentation is 30 DEG C, culture medium adds the ethanol of 4%,
When pH value is 6.5 to 7, acetic acid generative capacity and sugar decomposition ability are the most stable.
Vinegar contains the organic acid that the kinds more than 60 such as acetic acid, citric acid, aminoacid, succinic acid are above, has and contributes to tieing up
Accelerator effect in the various Nutrients Absorption bodies such as raw element and inorganic matter.Particularly, there is our meat of purification and the blood of blood
Liquid cleanser effect, promotes the metabolism of human body, improves natural curability, suppression chloasma and freckle to greatest extent, presses down
It is made as the lipid peroxide of skin aging main cause, the metabolism of active cell.Further, for decomposing the breast of skin and muscle
Acid, makes blood circulation smooth and easy.
Acetic acid compared with other organic acid, have the most excellent blood purification, antibacterial, prevent aging, promote new old generation
The ability thanked.
In an embodiment of the invention, above-mentioned Herba Menthae vinegar is by the cultivation side in liquid surface breeding microorganism
Prepared by method.
The Herba Menthae vinegar prepared by above-mentioned cultural method, be is characterized in that, the film of microorganism all the time with air contact, can be effective
Utilize the dissolved oxygen dissolved at liquid surface, not only there is the usefulness of Herba Menthae self component, and have and obtained by acetic fermentation
The usefulness arrived.
In an embodiment of the invention, any one or these during above-mentioned Herba Menthae refers to the leaf of Herba Menthae and stem
The extract of combination.
The leaf of Herba Menthae and stem have the sterilization of excellence, anthelminthic effect, can prevent halitosis, and institute is for toothpaste.Grind
When leaf is used as Wet-dressing agent, to the inflammation of skin, to dampen therapeutic effect good, the most effective to dermatitis, pruritus.It is right to contribute to
Injured by various degree and the skin of irriate plays calm effect, and reduce pruritus and abnormal response, give skin to live
Power and easing off the pressure, contributes to slight astriction and elastically keeps.The leaf of Herba Menthae contains the quintessence oil of 2% to 3%, Herba Menthae
Stem contain the quintessence oil within 1%.Account for quintessence oil about 70% Herba Menthae alkyd be the composition with Herba Menthae distinctive smell and drug effect.
The intrinsic fragrance of Herba Menthae is to obtain from menthol and menthone, and menthol has astringency, the skin of available take-up slack
Skin, the effect of pore refining, give good performance to skin.It addition, the mucosa of contract skin and blood vessel, give to part
Refrigerant sense.The menthol with special salubrious sense taste is colourless acicular crystal, is practically insoluble in water, but is easily dissolved in
Ethanol, chloroform.Obtaining from leaf or the stem of Herba Menthae, volume is put in mouth, will feel the stimulation to tongue, but time a small amount of,
Will feeling cool sense.
In an embodiment of the invention, above-mentioned cosmetic composition contains 'alpha '-hydroxy acids (AHA: α-Hydroxy
Acid).'alpha '-hydroxy acids is to add alcohol radical (Alcohol group) on the carbon that the alpha-position of carboxylic acid (Carboxylic acid) is put
Or the compound of hydroxyl (Hydroxy group), it is possible to reduce the ionic bond energy of horn cell, remove too much cutin, promote
The formation of new cell, shortens the cycle of the cornification processes of skin aging, promotes the activity of Skin Cell, thus improves skin.
It addition, promote the collagen protein according to fibrous bud cell (Fibroblast) and the generation of elastin laminin, obtain elastic and soft,
And promote, as the generation of the mucopolysaccharide (Mucopolysaccharide) of matrix components outside the important cells of corium, to promote
Skin moisture-keeping.
In an embodiment of the invention, the content of above-mentioned Herba Menthae vinegar is total relative to above-mentioned cosmetic composition
0.001 weight % of weight is to 20 weight %.When the content of above-mentioned Herba Menthae vinegar is less than 0.001 weight %, it is impossible to fully obtain
The effect of the object of the invention;When more than 20 weight %, the menthol contained in Herba Menthae vinegar becomes branch to produce temporary transient excitement.
In an embodiment of the invention, above-mentioned cosmetic composition is used for pore refining.Herba Menthae is carried out acetic acid
The Herba Menthae vinegar obtained that ferments has the excellent convergence usefulness maximization making Herba Menthae, prevents patulous follicular orifice, recovers pore elasticity
Contractive effect.
In an embodiment of the invention, above-mentioned cosmetic composition regulates for sebum.Herba Menthae is carried out acetic acid
The Herba Menthae vinegar that obtains of fermentation have promote skin blood purification, antibacterial, prevent effect aging, metabolic, the most permissible
Remove refuse and management pore.
The cosmetic composition that the present invention relates to is not particularly limited its dosage form, dosage form can turn to such as toner/smoothing toner, nutrition
Astringent, essence, massage cream, nourishing cream, facial film, gel or skin attachment class cosmetics.
Enumerate test example and dosage form example below, be further elaborated with composition and the effect of the present invention.But, these tests
Example and dosage form example are intended merely to help and understand that the present invention illustrates, and scope of the invention and scope are not limited to following example.
[preparation example]
At the acetobacter (Merk company, strain name: Acetobacter aceti KCTC 1010) with 2~3g
Culture medium (Mannitol Agar/YPM/Medium) in add 100g Herba Menthae material (Herba Menthae leaf 75~80 weight %,
Stem 20~25 weight %) inoculate after, at a temperature of about 26 DEG C ferment 48 hours, then in the fermented product obtained add
Extract solution (20ml Purified Water and the mixed liquor of 50ml ethanol), under room temperature (25 DEG C), carry out the extraction of 1 hour.By once
Filter [ultrafiltration (aperture=50 μm)], after removing ethanol and material, only collect pure fermented supernatant fluid.Supernatant is re-started
After centrifugation (ultracentrifugation seperator, 400rpm) and secondary filter [ultrafiltration (aperture=10 μm)], the filtrate obtained
The sterile solution of middle mixing 100ml (it is as the criterion with the volume that solution is overall, the Purified Water of 70%~94%, the fourth two of 5%~10%
Alcohol, the disodiumedetate of 0.01%~0.05% and 0.4%~the preservative (phenoxyethanol) of 1.0%), 120
Through 10~15 minutes sterilization process at DEG C, finally prepare the Herba Menthae vinegar of 100ml.
On the other hand, in order to contrast with the usefulness of Herba Menthae vinegar, Folium Menthae extract is prepared.This extract is, at 100g
Herba Menthae material (Herba Menthae leaf 75~80 weight %, stem 20~25 weight %) in add 100ml extraction solution (whole with solution
The volume of body is as the criterion, the Purified Water of 70%~95%, the butanediol of 5%~30%), extract at normal temperatures, prepare 100ml
Folium Menthae extract.
[embodiment and comparative example]
About containing the cosmetic composition of Herba Menthae vinegar as effective ingredient, by the preparation of following method, there is table 1 below
The cosmetic composition of the dosage form example 1 of composition.It addition, about containing the cosmetic composition of Herba Menthae vinegar as effective ingredient, for
Compare with the dosage form example 1 of the scope of the invention, be there is by the preparation of following method the change of the contrast dosage form example 1 of the composition of table 1 below
Cosmetic compositions.(unit: weight %)
Table 1
Being dissolved at normal temperatures in transparent aqueous phase, add and dissolve mutually and after uniform dissolution, addition Herba Menthae vinegar is the most molten
Solve, the cosmetic composition of preparation dosage form example 1.It addition, be dissolved at normal temperatures in transparent aqueous phase, add and dissolve mutually and uniform
After dissolving, it is added without Herba Menthae vinegar, and adds Folium Menthae extract, the cosmetic composition of preparation contrast dosage form example 1.The most molten
Solution becomes in transparent aqueous phase, adds and dissolves mutually and after uniform dissolution, is added without Herba Menthae vinegar and Folium Menthae extract, preparation contrast dosage form
Example 2.
[test example 1] evaluates skin pore and sebum improves usefulness
In order to confirm above-mentioned dosage form example 1, contrast dosage form example 1 and contrast the skin elasticity recovery effects of dosage form example 2, hair
Hole reduces effect and sebum regulating effects, with the women of 20 years old to 30 years old as object, measures its effect.Whole to the face of each group
After the dosage form of body even application dosage form example 1, contrast dosage form example 1 and contrast dosage form example 2, evaluate pore and zoom in effect and sebum tune
Joint usefulness.
This test is with the testee of Pass Test purpose as object, under the conditions of constant temperature and humidity, uses the most corresponding
Test products.Using the women testee with pore problem as object, use reagent by common using method, evaluate
Just use the pore management efficiency after reagent.
After washing one's face, take appropriate reagent (2mg/cm2), rub the massage whole face of uniform application on one side with the hands with hands is soft.Test
Period, testee is evaluated after and just using before a reagent uses, and testee washes one's face at minute
After, keep quite more than 15 minutes under the conditions of constant temperature and humidity (22 ± 2 DEG C, 40 ± 5RH%), then carry out as shown in table 2 below
The reagent of different minutes use and evaluate.
The mensuration of pore aperture, sebum size and quantity when the reagent of this test example is used for skin is to utilize (strain) to like
The Skin Touch determinator of jasmine Pacific Ocean exploitation is evaluated.Skin Touch carries out skin by one-piece type sensor
Oil divide, the mensuration of moisture, DE, measurement result shows at outside LCD display window.Skin Touch is utilized to measure in examination
Before agent uses, the one week after of uses, use two weeks after etc. test position, reagent is used for pore hole during skin by evaluation
Footpath, sebum size and quantity.
Table 2
Its result, about face's pore position, statistical result as shown in table 3, contains reagent with as effective ingredient
Comparing before use, the sebum quantity after just using, sebum size (unit: A.U.), pore aperture (unit: A.U.) effectively subtract
Few.
Table 3
Can confirm that there is the dosage form example 1 of shrinking pore and sebum regulating effects from the result of above-mentioned table 3 and Fig. 1 to Figure 12
Compared with contrast dosage form example 1 and contrast dosage form example 2, pore shrinks, sebum quantity reduces and the improvement excellent effect of number of pores.
Claims (8)
1. a cosmetic composition, this cosmetic composition contains Herba Menthae vinegar as effective ingredient.
Cosmetic composition the most according to claim 1, it is characterised in that described Herba Menthae vinegar is to be carried out by Folium Menthae extract
Acetic fermentation obtains.
Cosmetic composition the most according to claim 2, it is characterised in that described acetic fermentation uses acetobacter
(Acetobacter aceti)。
Cosmetic composition the most according to claim 2, it is characterised in that described Folium Menthae extract be Herba Menthae leaf and
Any one in stem or the extract of these combinations.
Cosmetic composition the most according to claim 1, it is characterised in that described cosmetic composition contains Alpha-hydroxy
Acid.
Cosmetic composition the most according to claim 1, it is characterised in that the content of described Herba Menthae vinegar is relative to described
0.001 weight % of the gross weight of cosmetic composition is to 20 weight %.
Cosmetic composition the most according to claim 1, it is characterised in that described cosmetic composition is used for reducing hair
Hole.
Cosmetic composition the most according to claim 1, it is characterised in that described cosmetic composition is used for regulating skin
Fat.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020140049216A KR102249700B1 (en) | 2014-04-24 | 2014-04-24 | Comsmetic composition comprising mint vinegar |
KR10-2014-0049216 | 2014-04-24 | ||
PCT/KR2015/002965 WO2015163589A1 (en) | 2014-04-24 | 2015-03-26 | Cosmetic composition containing mentha haplocalyx as active ingredient |
Publications (2)
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CN106232101A true CN106232101A (en) | 2016-12-14 |
CN106232101B CN106232101B (en) | 2020-02-28 |
Family
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CN201580021097.7A Active CN106232101B (en) | 2014-04-24 | 2015-03-26 | Cosmetic composition containing peppermint vinegar as active ingredient |
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JP (2) | JP2017513876A (en) |
KR (1) | KR102249700B1 (en) |
CN (1) | CN106232101B (en) |
SG (1) | SG11201608845PA (en) |
WO (1) | WO2015163589A1 (en) |
Cited By (1)
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CN111655225A (en) * | 2017-06-30 | 2020-09-11 | 株式会社爱茉莉太平洋 | Composition comprising Mentha arvensis extract for treating skin cell damage caused by dust, enhancing skin barrier, and anti-aging or anti-inflammatory |
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Publication number | Priority date | Publication date | Assignee | Title |
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KR102212626B1 (en) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | Composition comprising Mentha Arvensis Extract for Enhancing Skin Barrier |
KR102212625B1 (en) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | Composition comprising Mentha Arvensis Extract for anti-aging or anti-inflammation |
KR102212627B1 (en) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | Composition comprising Mentha Arvensis Extract for caring damages of skin cells by microdust |
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- 2015-03-26 SG SG11201608845PA patent/SG11201608845PA/en unknown
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- 2015-03-26 JP JP2016563931A patent/JP2017513876A/en active Pending
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采薇: "《从头到脚的美丽圣经》", 30 June 2012, 中国纺织出版社 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111655225A (en) * | 2017-06-30 | 2020-09-11 | 株式会社爱茉莉太平洋 | Composition comprising Mentha arvensis extract for treating skin cell damage caused by dust, enhancing skin barrier, and anti-aging or anti-inflammatory |
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KR20150122983A (en) | 2015-11-03 |
WO2015163589A1 (en) | 2015-10-29 |
KR102249700B1 (en) | 2021-05-10 |
JP2017513876A (en) | 2017-06-01 |
JP6894991B2 (en) | 2021-06-30 |
SG11201608845PA (en) | 2016-11-29 |
CN106232101B (en) | 2020-02-28 |
JP2020100663A (en) | 2020-07-02 |
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