JP2017513826A5 - - Google Patents

Download PDF

Info

Publication number
JP2017513826A5
JP2017513826A5 JP2016560695A JP2016560695A JP2017513826A5 JP 2017513826 A5 JP2017513826 A5 JP 2017513826A5 JP 2016560695 A JP2016560695 A JP 2016560695A JP 2016560695 A JP2016560695 A JP 2016560695A JP 2017513826 A5 JP2017513826 A5 JP 2017513826A5
Authority
JP
Japan
Prior art keywords
amino acid
group
substituted
composition
aryl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016560695A
Other languages
English (en)
Japanese (ja)
Other versions
JP6642887B2 (ja
JP2017513826A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/023883 external-priority patent/WO2015153761A2/en
Publication of JP2017513826A publication Critical patent/JP2017513826A/ja
Publication of JP2017513826A5 publication Critical patent/JP2017513826A5/ja
Application granted granted Critical
Publication of JP6642887B2 publication Critical patent/JP6642887B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016560695A 2014-04-02 2015-04-01 アルファヘリックスを模倣した大環状ペプチドミメティック Expired - Fee Related JP6642887B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461973994P 2014-04-02 2014-04-02
US61/973,994 2014-04-02
PCT/US2015/023883 WO2015153761A2 (en) 2014-04-02 2015-04-01 Macrocyclic peptidomimetics for alpha-helix mimicry

Publications (3)

Publication Number Publication Date
JP2017513826A JP2017513826A (ja) 2017-06-01
JP2017513826A5 true JP2017513826A5 (enExample) 2018-05-17
JP6642887B2 JP6642887B2 (ja) 2020-02-12

Family

ID=54241434

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016560695A Expired - Fee Related JP6642887B2 (ja) 2014-04-02 2015-04-01 アルファヘリックスを模倣した大環状ペプチドミメティック

Country Status (6)

Country Link
US (1) US10294273B2 (enExample)
EP (1) EP3126375B1 (enExample)
JP (1) JP6642887B2 (enExample)
CN (1) CN106604928A (enExample)
CA (1) CA2944651A1 (enExample)
WO (1) WO2015153761A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10827064B2 (en) 2016-06-13 2020-11-03 Google Llc Automated call requests with status updates
KR102155763B1 (ko) 2016-06-13 2020-09-16 구글 엘엘씨 인간 운영자로의 에스컬레이션
WO2018227053A1 (en) * 2017-06-09 2018-12-13 Bristol-Myers Squibb Company Non-chromatographic purification of macrocyclic peptides by a resin catch and release
US11524979B2 (en) 2017-06-15 2022-12-13 University Of Washington Macrocyclic polypeptides
CA3078504A1 (en) 2017-10-04 2019-04-11 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
CN111447941B (zh) * 2017-10-27 2023-10-31 俄亥俄州国家创新基金会 用于细胞内递送装订肽的多肽缀合物
US11793884B2 (en) 2018-01-29 2023-10-24 Ohio State Innovation Foundation Cyclic peptidyl inhibitors of CAL-PDZ binding domain
US11987647B2 (en) 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
EP4661382A2 (en) 2019-05-06 2025-12-10 Google Llc Automated calling system
US11158321B2 (en) 2019-09-24 2021-10-26 Google Llc Automated calling system
EP3909230B1 (en) 2020-03-20 2024-10-23 Google LLC Semi-delegated calling by an automated assistant on behalf of human participant
US11303749B1 (en) 2020-10-06 2022-04-12 Google Llc Automatic navigation of an interactive voice response (IVR) tree on behalf of human user(s)
WO2023107353A2 (en) * 2021-12-10 2023-06-15 Merck Sharp & Dohme Llc P53 peptidomimetic macrocycles
TW202417465A (zh) 2022-08-23 2024-05-01 日商富士軟片股份有限公司 環肽或其鹽及mdmx抑制劑
WO2024054892A1 (en) * 2022-09-09 2024-03-14 Shape Therapeutics Inc. Therapeutic peptides
US12225158B2 (en) 2022-12-15 2025-02-11 Google Llc System(s) and method(s) for implementing a personalized chatbot
KR20250134670A (ko) 2023-01-16 2025-09-11 암브룩스, 인코포레이티드 항-cd70 항체-약물 접합체
US12581015B2 (en) 2023-03-21 2026-03-17 Google Llc Automating telephone call(s) on behalf of user(s)
AR131133A1 (es) 2023-05-24 2025-02-19 Ambrx Inc INTERFERÓN l BOVINO PEGILADO Y MÉTODOS DE USO DEL MISMO

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083983B2 (en) 1996-07-05 2006-08-01 Cancer Research Campaign Technology Limited Inhibitors of the interaction between P53 and MDM2
US8193310B2 (en) * 2004-03-19 2012-06-05 The University Of Queensland Alpha helical mimics, their uses and methods for their production
US7960506B2 (en) * 2006-12-14 2011-06-14 Aileron Therapeutics, Inc. Bis-sulfhydryl macrocyclization systems
EP2242503A4 (en) * 2008-02-08 2012-04-25 Aileron Therapeutics Inc THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES
US8343760B2 (en) * 2008-06-05 2013-01-01 University Of Maryland, Baltimore p53 activator peptides
JP2012503025A (ja) * 2008-09-22 2012-02-02 エルロン・セラピューティクス・インコーポレイテッド 精製されたポリペプチド組成物を調製するための方法
JP2012515172A (ja) * 2009-01-14 2012-07-05 エルロン・セラピューティクス・インコーポレイテッド ペプチド模倣大環状分子
WO2011038049A1 (en) * 2009-09-22 2011-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
KR20130099938A (ko) * 2010-08-13 2013-09-06 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
US9029332B2 (en) * 2010-12-15 2015-05-12 The Research Foundation For The State University Of New York Cross-linked peptides and proteins, methods of making same, and uses thereof
US8986953B2 (en) * 2011-01-20 2015-03-24 University Of Rochester Macrocyclic compounds with a hybrid peptidic/non-peptidic backbone and methods for their preparation

Similar Documents

Publication Publication Date Title
JP2017513826A5 (enExample)
ES2387685T3 (es) Péptido WT1 restringido por HLA-A*3303 y composición farmacéutica que comprende el mismo
RU2018131636A (ru) Новые конъюгаты аманитина
US20160264636A1 (en) Peptide inhibitors of tead/yap-taz interaction
JP2017006120A5 (enExample)
CY1117437T1 (el) Αντισωματα αντι-μεσοθηλινης και χρησεις αυτων
RU2007136026A (ru) Варианты ил-21
JP2019501141A5 (enExample)
EA201891681A1 (ru) Новая иммуностимулирующая векторная система
MX2020000413A (es) Una vacuna universal basada en neoantigenos de tumor compartidos para prevencion y tratamiento de canceres inestables de microsatelite (msi).
JP2015522264A5 (enExample)
WO2020022898A3 (en) Off-the-shelf cancer vaccines
JP2017533728A (ja) トランスフェリン受容体(tfr)に対するrnaアプタマー
NZ723940A (en) Beta-substituted beta-amino acids and analogs as chemotherapeutic agents
JP2018507689A5 (enExample)
BR112012025567A2 (pt) peptídeos de cdca5 e vacinas que incluem os mesmos
CA2432971A1 (en) Polypeptides
RU2013108262A (ru) Новые пептиды с анальгетическим эффектом, ингибирующие asic-rfyfks
FI3335725T3 (fi) Pds5a-epitooppeja immuuniteetin indusoijina
CN108452322A (zh) 基于长链非编码rna的bcl2基因抑制剂
CN112739381A (zh) 使用了hsp47的抑制物质的癌转移抑制
AR113982A1 (es) Péptido antagonista de la actividad de la interleucina-15
MX2012011385A (es) Peptidos ect2 y vacunas que los incluyen.
AR128014A1 (es) Polipéptidos de penetración celular (cpp) y su uso en terapia humana
EP2545171A4 (en) HJURP PEPTIDES AND VACCINES CONTAINING THEM