JP2017512774A5 - - Google Patents

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Publication number
JP2017512774A5
JP2017512774A5 JP2016557214A JP2016557214A JP2017512774A5 JP 2017512774 A5 JP2017512774 A5 JP 2017512774A5 JP 2016557214 A JP2016557214 A JP 2016557214A JP 2016557214 A JP2016557214 A JP 2016557214A JP 2017512774 A5 JP2017512774 A5 JP 2017512774A5
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JP
Japan
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item
items
protecting group
protected
nucleobase
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Pending
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JP2016557214A
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English (en)
Japanese (ja)
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JP2017512774A (ja
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Priority claimed from PCT/US2015/020761 external-priority patent/WO2015142735A1/en
Publication of JP2017512774A publication Critical patent/JP2017512774A/ja
Publication of JP2017512774A5 publication Critical patent/JP2017512774A5/ja
Pending legal-status Critical Current

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JP2016557214A 2014-03-16 2015-03-16 二環式ヌクレオシドの合成 Pending JP2017512774A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461953889P 2014-03-16 2014-03-16
US61/953,889 2014-03-16
PCT/US2015/020761 WO2015142735A1 (en) 2014-03-16 2015-03-16 Synthesis of bicyclic nucleosides

Publications (2)

Publication Number Publication Date
JP2017512774A JP2017512774A (ja) 2017-05-25
JP2017512774A5 true JP2017512774A5 (enExample) 2018-03-08

Family

ID=54145178

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016557214A Pending JP2017512774A (ja) 2014-03-16 2015-03-16 二環式ヌクレオシドの合成

Country Status (6)

Country Link
US (1) US10030042B2 (enExample)
EP (1) EP3119796A4 (enExample)
JP (1) JP2017512774A (enExample)
CN (1) CN106459135A (enExample)
CA (1) CA2940440A1 (enExample)
WO (1) WO2015142735A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014233115B2 (en) * 2013-03-15 2019-08-01 MiRagen Therapeutics, Inc. Bridged bicyclic nucleosides
WO2018009466A1 (en) 2016-07-05 2018-01-11 Aduro Biotech, Inc. Locked nucleic acid cyclic dinucleotide compounds and uses thereof
WO2018102397A1 (en) 2016-11-29 2018-06-07 PureTech Health LLC Exosomes for delivery of therapeutic agents
WO2018215049A1 (en) * 2017-05-23 2018-11-29 F. Hoffmann-La Roche Ag Process for galnac oligonucleotide conjugates
US20220403436A1 (en) * 2019-09-23 2022-12-22 Dna Script Increasing Long-Sequence Yields in Template-Free Enzymatic Synthesis of Polynucleotides
CN114685560B (zh) * 2020-12-31 2024-05-14 沈阳药科大学 含哌啶骨架亚磷酰胺单体及寡聚核苷酸的合成和应用
AU2022352676A1 (en) * 2021-09-22 2024-03-14 Sanegene Bio Usa Inc. 2'-alkyl or 3'- alkyl modified ribose derivatives for use in the in-vivo delivery of oligonucleotides
CN116606338A (zh) * 2023-05-18 2023-08-18 中国人民解放军军事科学院军事医学研究院 6’-氰基修饰的锁核苷、核苷酸和核酸聚合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833361B2 (en) * 1998-05-26 2004-12-21 Ribapharm, Inc. Nucleosides having bicyclic sugar moiety
WO1999060855A1 (en) * 1998-05-26 1999-12-02 Icn Pharmaceuticals, Inc. Novel nucleosides having bicyclic sugar moiety
WO2011085102A1 (en) 2010-01-11 2011-07-14 Isis Pharmaceuticals, Inc. Base modified bicyclic nucleosides and oligomeric compounds prepared therefrom
CA2863253A1 (en) * 2011-09-07 2013-03-14 Marina Biotech, Inc. Synthesis and uses of nucleic acid compounds with conformationally restricted monomers
AU2014233115B2 (en) 2013-03-15 2019-08-01 MiRagen Therapeutics, Inc. Bridged bicyclic nucleosides

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