JP2017508749A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017508749A5 JP2017508749A5 JP2016555554A JP2016555554A JP2017508749A5 JP 2017508749 A5 JP2017508749 A5 JP 2017508749A5 JP 2016555554 A JP2016555554 A JP 2016555554A JP 2016555554 A JP2016555554 A JP 2016555554A JP 2017508749 A5 JP2017508749 A5 JP 2017508749A5
- Authority
- JP
- Japan
- Prior art keywords
- bladder
- gemcitabine
- patient
- day
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 34
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 32
- 229960005277 gemcitabine Drugs 0.000 claims 32
- 229940079593 drug Drugs 0.000 claims 13
- 238000011200 topical administration Methods 0.000 claims 6
- 238000012377 drug delivery Methods 0.000 claims 5
- 210000002700 urine Anatomy 0.000 claims 5
- 230000002459 sustained effect Effects 0.000 claims 4
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 239000002357 osmotic agent Substances 0.000 claims 3
- 239000002562 thickening agent Substances 0.000 claims 3
- 206010005003 Bladder cancer Diseases 0.000 claims 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 2
- 239000004202 carbamide Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 201000005112 urinary bladder cancer Diseases 0.000 claims 2
- 210000005068 bladder tissue Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000003232 mucoadhesive effect Effects 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000005086 pumping Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000005063 solubilization Methods 0.000 claims 1
- 230000007928 solubilization Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461949215P | 2014-03-06 | 2014-03-06 | |
| US61/949,215 | 2014-03-06 | ||
| PCT/US2015/019262 WO2015134911A1 (en) | 2014-03-06 | 2015-03-06 | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019184023A Division JP7061595B2 (ja) | 2014-03-06 | 2019-10-04 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017508749A JP2017508749A (ja) | 2017-03-30 |
| JP2017508749A5 true JP2017508749A5 (https=) | 2018-03-08 |
| JP6901858B2 JP6901858B2 (ja) | 2021-07-14 |
Family
ID=52697553
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016555554A Active JP6901858B2 (ja) | 2014-03-06 | 2015-03-06 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2019184023A Active JP7061595B2 (ja) | 2014-03-06 | 2019-10-04 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2021183995A Active JP7383681B2 (ja) | 2014-03-06 | 2021-11-11 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2023190543A Active JP7802743B2 (ja) | 2014-03-06 | 2023-11-08 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2026001498A Pending JP2026062972A (ja) | 2014-03-06 | 2026-01-07 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019184023A Active JP7061595B2 (ja) | 2014-03-06 | 2019-10-04 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2021183995A Active JP7383681B2 (ja) | 2014-03-06 | 2021-11-11 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2023190543A Active JP7802743B2 (ja) | 2014-03-06 | 2023-11-08 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
| JP2026001498A Pending JP2026062972A (ja) | 2014-03-06 | 2026-01-07 | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20150250717A1 (https=) |
| EP (2) | EP4124339B1 (https=) |
| JP (5) | JP6901858B2 (https=) |
| KR (1) | KR102338079B1 (https=) |
| CN (2) | CN106102751A (https=) |
| AU (4) | AU2015226901B2 (https=) |
| BR (1) | BR112016020381A8 (https=) |
| CA (1) | CA2939979C (https=) |
| DK (2) | DK4124339T3 (https=) |
| ES (2) | ES2930435T3 (https=) |
| FI (1) | FI4124339T3 (https=) |
| HR (2) | HRP20251264T1 (https=) |
| HU (1) | HUE060704T2 (https=) |
| IL (2) | IL247347B2 (https=) |
| LT (2) | LT4124339T (https=) |
| MX (1) | MX2016011333A (https=) |
| PL (2) | PL3113782T3 (https=) |
| PT (2) | PT3113782T (https=) |
| RS (2) | RS67337B1 (https=) |
| RU (1) | RU2694902C1 (https=) |
| SG (2) | SG11201607342QA (https=) |
| SI (1) | SI4124339T1 (https=) |
| SM (2) | SMT202200449T1 (https=) |
| WO (1) | WO2015134911A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX367070B (es) | 2012-08-31 | 2019-08-05 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata. |
| KR102385603B1 (ko) | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| LT4124339T (lt) * | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| CN118453872A (zh) * | 2016-05-06 | 2024-08-09 | 塔里斯生物医药公司 | 治疗下尿路尿道上皮癌的方法 |
| BR112020000832A2 (pt) * | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| JOP20200124A1 (ar) * | 2017-11-08 | 2020-05-20 | Taris Biomedical Llc | طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| EP4039279A4 (en) * | 2019-10-03 | 2023-11-01 | Seikagaku Corporation | TRANSMUCOSAL MEDICINAL ACTIVE DELIVERY SYSTEM FOR THE BLADDER SUBMUCOSA |
| RU2713443C2 (ru) * | 2019-11-01 | 2020-02-05 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ комбинированного лечения мышечно-инвазивного рака мочевого пузыря т3-т4 n0-+m0 |
| US20230073301A1 (en) * | 2020-01-27 | 2023-03-09 | Isola Therapeutics, Inc. | Tissue dosing for intraluminal local drug delivery |
| CN112169066B (zh) * | 2020-10-29 | 2023-05-12 | 安徽省立医院(中国科学技术大学附属第一医院) | 具有控制器的连续缓释给药留置管 |
| CN113616666A (zh) * | 2021-08-24 | 2021-11-09 | 傅广波 | 膀胱黏膜下注射吉西他滨在治疗膀胱癌中的应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4111203A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system with means for improving delivery kinetics of system |
| US6171298B1 (en) | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
| EP1372602B1 (en) | 2001-01-09 | 2007-04-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
| AU2003278881A1 (en) * | 2002-09-23 | 2004-04-08 | Microchips, Inc. | Micro-reservoir osmotic release systems and microtube array device |
| CA2503193A1 (en) | 2002-10-22 | 2004-05-06 | The Biomerix Corporation | Method and system for intravesicular delivery of therapeutic agents |
| ATE387236T1 (de) * | 2003-03-31 | 2008-03-15 | Alza Corp | Osmotische pumpe mit mitteln zum ableiten des innendrucks |
| US8361490B2 (en) | 2004-09-16 | 2013-01-29 | Theracoat Ltd. | Biocompatible drug delivery apparatus and methods |
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| WO2007145704A2 (en) * | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| EP1913962A1 (en) | 2006-10-22 | 2008-04-23 | Ophir Perelson | Expandable medical device for the treatment and prevention of cardiovascular diseases |
| KR101538748B1 (ko) | 2007-12-11 | 2015-07-22 | 메사추세츠 인스티튜트 오브 테크놀로지 | 이식형 의약 투여 장치와 방광과 기타 신체 낭 또는 내강의 치료 방법 |
| CA2720523C (en) | 2008-04-04 | 2013-12-17 | Lipella Pharmaceuticals, Inc. | Treatment of bladder dysfunction using liposomal botulinum toxin |
| EP2313122B1 (en) | 2008-07-17 | 2019-03-06 | Micell Technologies, Inc. | Drug delivery medical device |
| EA201170297A1 (ru) | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| DK2445570T3 (da) | 2009-06-26 | 2013-02-25 | Taris Biomedical Inc | Implanterbare lægemiddelafgivelsesindretninger samt fremgangsmåder til deres fremstilling |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| ES2732150T3 (es) * | 2010-01-20 | 2019-11-20 | Urogen Pharma Ltd | Material y método para tratar cavidades internas |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| WO2011153009A1 (en) | 2010-06-02 | 2011-12-08 | Abraxis Bioscience, Llc | Methods of treating bladder cancer |
| EP3795121A1 (en) | 2010-08-05 | 2021-03-24 | TARIS Biomedical LLC | Ureteral stent drug delivery device |
| WO2012048114A1 (en) | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Time-selective bioresorbable or collapsible drug delivery systems and methods |
| US9457176B2 (en) | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| MX365807B (es) | 2010-10-27 | 2019-06-14 | Prometic Pharma Smt Ltd | Compuestos y composiciones para el tratamiento del cáncer. |
| US8979797B2 (en) | 2010-12-16 | 2015-03-17 | Ams Research Corporation | High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics |
| JP2014503554A (ja) | 2011-01-10 | 2014-02-13 | タリス バイオメディカル，インコーポレイテッド | 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン |
| EP2670398B1 (en) * | 2011-02-04 | 2017-06-07 | TARIS Biomedical LLC | Implantable device for controlled release of low solubility drug |
| US20150005595A1 (en) | 2011-12-30 | 2015-01-01 | Kibur Medical, Inc. | Implantable devices and methods for evaluation of active agents |
| CN104470535A (zh) | 2012-03-29 | 2015-03-25 | 阿尔托生物科学有限公司 | 用于治疗肿瘤的方法 |
| WO2013170069A1 (en) | 2012-05-09 | 2013-11-14 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
| MX367070B (es) * | 2012-08-31 | 2019-08-05 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata. |
| SG11201501424SA (en) | 2012-08-31 | 2015-03-30 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer comprising oxaliplatin |
| MX379066B (es) | 2012-09-18 | 2025-03-04 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior. |
| JP2016508842A (ja) | 2013-03-05 | 2016-03-24 | タリス バイオメディカル エルエルシー | 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法 |
| EP2968120B1 (en) | 2013-03-15 | 2026-01-14 | TARIS Biomedical LLC | Drug delivery devices and methods for drug delivery |
| KR102557326B1 (ko) * | 2013-03-15 | 2023-07-19 | 타리스 바이오메디컬 엘엘씨 | 약물-투과성 구성요소를 가지는 약물 전달 장치 |
| CA2944480C (en) | 2013-04-10 | 2021-05-18 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
| KR102385603B1 (ko) * | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| EP3065807A1 (en) * | 2013-11-05 | 2016-09-14 | TARIS Biomedical LLC | Osmotic drug delivery devices, kits, and methods |
| LT4124339T (lt) | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| RU2591946C2 (ru) | 2014-06-24 | 2016-07-20 | Владимир Эдуардович Анников | Способ изготовления гелеобразного водосодержащего взрывчатого состава |
| KR20220061253A (ko) | 2014-06-26 | 2022-05-12 | 타리스 바이오메디컬 엘엘씨 | 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 |
| WO2016172704A1 (en) | 2015-04-23 | 2016-10-27 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| CN118453872A (zh) | 2016-05-06 | 2024-08-09 | 塔里斯生物医药公司 | 治疗下尿路尿道上皮癌的方法 |
| BR112020000832A2 (pt) | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| JOP20200124A1 (ar) | 2017-11-08 | 2020-05-20 | Taris Biomedical Llc | طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
-
2015
- 2015-03-06 LT LTEP22196596.5T patent/LT4124339T/lt unknown
- 2015-03-06 ES ES15711373T patent/ES2930435T3/es active Active
- 2015-03-06 SG SG11201607342QA patent/SG11201607342QA/en unknown
- 2015-03-06 JP JP2016555554A patent/JP6901858B2/ja active Active
- 2015-03-06 SM SM20220449T patent/SMT202200449T1/it unknown
- 2015-03-06 DK DK22196596.5T patent/DK4124339T3/da active
- 2015-03-06 ES ES22196596T patent/ES3051417T3/es active Active
- 2015-03-06 CN CN201580011259.9A patent/CN106102751A/zh active Pending
- 2015-03-06 CA CA2939979A patent/CA2939979C/en active Active
- 2015-03-06 SM SM20250385T patent/SMT202500385T1/it unknown
- 2015-03-06 RS RS20251017A patent/RS67337B1/sr unknown
- 2015-03-06 HR HRP20251264TT patent/HRP20251264T1/hr unknown
- 2015-03-06 IL IL247347A patent/IL247347B2/en unknown
- 2015-03-06 HU HUE15711373A patent/HUE060704T2/hu unknown
- 2015-03-06 WO PCT/US2015/019262 patent/WO2015134911A1/en not_active Ceased
- 2015-03-06 PT PT157113739T patent/PT3113782T/pt unknown
- 2015-03-06 PL PL15711373.9T patent/PL3113782T3/pl unknown
- 2015-03-06 KR KR1020167027303A patent/KR102338079B1/ko active Active
- 2015-03-06 BR BR112016020381A patent/BR112016020381A8/pt not_active Application Discontinuation
- 2015-03-06 HR HRP20221252TT patent/HRP20221252T1/hr unknown
- 2015-03-06 CN CN202510128139.2A patent/CN119950539A/zh active Pending
- 2015-03-06 PL PL22196596.5T patent/PL4124339T3/pl unknown
- 2015-03-06 US US14/641,009 patent/US20150250717A1/en not_active Abandoned
- 2015-03-06 LT LTEPPCT/US2015/019262T patent/LT3113782T/lt unknown
- 2015-03-06 IL IL311410A patent/IL311410B2/en unknown
- 2015-03-06 MX MX2016011333A patent/MX2016011333A/es unknown
- 2015-03-06 DK DK15711373.9T patent/DK3113782T3/da active
- 2015-03-06 SI SI201532080T patent/SI4124339T1/sl unknown
- 2015-03-06 RS RS20220937A patent/RS63675B1/sr unknown
- 2015-03-06 SG SG10202101978SA patent/SG10202101978SA/en unknown
- 2015-03-06 AU AU2015226901A patent/AU2015226901B2/en active Active
- 2015-03-06 EP EP22196596.5A patent/EP4124339B1/en active Active
- 2015-03-06 PT PT221965965T patent/PT4124339T/pt unknown
- 2015-03-06 RU RU2016136103A patent/RU2694902C1/ru active
- 2015-03-06 EP EP15711373.9A patent/EP3113782B1/en active Active
- 2015-03-06 FI FIEP22196596.5T patent/FI4124339T3/fi active
-
2019
- 2019-10-04 JP JP2019184023A patent/JP7061595B2/ja active Active
-
2020
- 2020-08-12 AU AU2020217383A patent/AU2020217383B2/en active Active
-
2021
- 2021-11-11 JP JP2021183995A patent/JP7383681B2/ja active Active
- 2021-12-23 US US17/561,540 patent/US20220117886A1/en not_active Abandoned
-
2022
- 2022-07-07 US US17/811,296 patent/US12582599B2/en active Active
- 2022-08-08 AU AU2022215156A patent/AU2022215156B2/en active Active
-
2023
- 2023-11-08 JP JP2023190543A patent/JP7802743B2/ja active Active
-
2024
- 2024-11-08 AU AU2024259822A patent/AU2024259822A1/en active Pending
-
2026
- 2026-01-07 JP JP2026001498A patent/JP2026062972A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017508749A5 (https=) | ||
| JP7802743B2 (ja) | 薬物送達システム及びゲムシタビンによる膀胱がんの治療方法 | |
| JP6309009B2 (ja) | 前立腺の治療のための薬物送達システム及び方法 | |
| JP6463266B2 (ja) | 膀胱癌の治療のためのオキサリプラチンを含む薬物送達システム及び方法 | |
| KR102141433B1 (ko) | 트로스피움을 이용함으로써 방광 배뇨 장애 및 다른 하부 요도관 장애의 치료를 위한 약물 전달 시스템과 방법 | |
| JP2015529688A5 (https=) | ||
| HK40042011A (en) | Drug delivery systems and methods for treatment of prostate |