JP2017506064A5 - - Google Patents
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- JP2017506064A5 JP2017506064A5 JP2016545358A JP2016545358A JP2017506064A5 JP 2017506064 A5 JP2017506064 A5 JP 2017506064A5 JP 2016545358 A JP2016545358 A JP 2016545358A JP 2016545358 A JP2016545358 A JP 2016545358A JP 2017506064 A5 JP2017506064 A5 JP 2017506064A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- antibody
- derivative
- cell
- number pta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012634 fragment Substances 0.000 claims 22
- 210000004408 hybridoma Anatomy 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 11
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 101001095308 Homo sapiens Periostin Proteins 0.000 claims 2
- 210000000628 antibody-producing cell Anatomy 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 102000048431 human POSTN Human genes 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 241000271566 Aves Species 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 claims 1
- DZBUGLKDJFMEHC-UHFFFAOYSA-O acridine;hydron Chemical compound C1=CC=CC2=CC3=CC=CC=C3[NH+]=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-O 0.000 claims 1
- 210000004102 animal cell Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229910052707 ruthenium Inorganic materials 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461936967P | 2014-02-07 | 2014-02-07 | |
| US61/936,967 | 2014-02-07 | ||
| PCT/US2015/014652 WO2015120171A1 (en) | 2014-02-07 | 2015-02-05 | Novel assay to detect human periostin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019139534A Division JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017506064A JP2017506064A (ja) | 2017-03-02 |
| JP2017506064A5 true JP2017506064A5 (https=) | 2017-08-10 |
Family
ID=52574429
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016545358A Pending JP2017506064A (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2016544101A Expired - Fee Related JP6549132B2 (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2019139534A Pending JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544101A Expired - Fee Related JP6549132B2 (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2019139534A Pending JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10775388B2 (https=) |
| EP (2) | EP3102951A1 (https=) |
| JP (3) | JP2017506064A (https=) |
| KR (2) | KR20160122756A (https=) |
| CN (2) | CN106164675B (https=) |
| AU (2) | AU2015214103A1 (https=) |
| BR (2) | BR112016017901A2 (https=) |
| CA (2) | CA2936285A1 (https=) |
| HK (2) | HK1232238A1 (https=) |
| MX (2) | MX2016009490A (https=) |
| RU (2) | RU2016135418A (https=) |
| SG (2) | SG11201606322XA (https=) |
| TW (1) | TW201542589A (https=) |
| WO (2) | WO2015120171A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018538249A (ja) | 2015-11-04 | 2018-12-27 | アストラゼネカ アクチボラグ | 好酸球性疾患における好酸球標的化治療薬に対する臨床応答の予測変数としてのジペプチジルペプチダーゼ−４およびペリオスチン |
| JP7006599B2 (ja) * | 2016-08-10 | 2022-02-10 | 株式会社シノテスト | 試料に含まれるペリオスチンの測定試薬、ペリオスチン測定用前処理剤、ペリオスチン測定方法及びペリオスチン測定の感度の改善方法 |
| JPWO2018194134A1 (ja) * | 2017-04-20 | 2020-02-27 | 株式会社シノテスト | 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法 |
| CA3093422A1 (en) | 2018-03-19 | 2019-09-26 | Bioventures, Llc | Periostin antibodies and methods of using the same |
| CN109879963A (zh) * | 2019-03-15 | 2019-06-14 | 辽宁何氏医学院 | 一种抑制组织器官纤维化和新生血管形成的单克隆抗体及其制备方法和应用 |
| MX2021012952A (es) | 2019-04-26 | 2022-01-04 | Univ Cornell | Vacuna klebsiella y metodos de uso. |
| TW202342979A (zh) * | 2021-12-28 | 2023-11-01 | 日商積水醫療股份有限公司 | 檢測方法及檢測試劑 |
| CN115078734A (zh) * | 2022-06-15 | 2022-09-20 | 苏州方达新药开发有限公司 | 一种细胞因子融合蛋白的检测分析方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0279582A3 (en) | 1987-02-17 | 1989-10-18 | Pharming B.V. | Dna sequences to target proteins to the mammary gland for efficient secretion |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| GB0407315D0 (en) | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
| CN101189033B (zh) | 2005-05-30 | 2012-03-28 | 株式会社器官再生工学 | 牙齿的制造方法、牙齿的集合体及组织的制造方法 |
| RU2421464C2 (ru) | 2005-10-21 | 2011-06-20 | Новартис Аг | Человеческие антитела к il-13 и их терапевтическое применение |
| CA2635849C (en) * | 2005-12-28 | 2017-05-09 | Asubio Pharma Co., Ltd. | An antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved |
| US8017119B2 (en) | 2005-12-28 | 2011-09-13 | Daiichi Sankyo Company, Ltd. | Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved |
| KR101560843B1 (ko) | 2007-06-27 | 2015-10-15 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 페리오스틴의 Ｅｘｏｎ-17 부위에 의해 코드되는 펩티드에 대한 항체를 함유하는 암 치료제 |
| EP2631302A3 (en) | 2008-03-31 | 2014-01-08 | Genentech, Inc. | Compositions and methods for treating and diagnosing asthma |
| CN102065895A (zh) * | 2008-04-11 | 2011-05-18 | 比奥根艾迪克Ma公司 | 抗-igf-1r抗体和其它化合物的治疗联合 |
| FR2946349B1 (fr) * | 2009-06-03 | 2013-10-04 | Synarc Sas | Sequences, anticorps, procedes et necessaires pour la detection et le dosage in vitro de la periostine, en vue du diagnostic du suivi ou du pronostic de pathologies ou de phenomenes biologiques impliquant la periostine |
| TWI732259B (zh) * | 2010-12-16 | 2021-07-01 | 美商建南德克公司 | 關於th2抑制作用之診斷及治療 |
| JP2014518626A (ja) | 2011-05-18 | 2014-08-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 被験者が慢性腎疾患を有する、または発症するリスクがあるかどうかを決定するための方法 |
| EP2710370A4 (en) | 2011-05-18 | 2015-01-07 | Medimmune Llc | METHODS OF DIAGNOSING AND TREATING PULMONARY DISEASES OR DISORDERS |
| WO2013035799A1 (ja) | 2011-09-06 | 2013-03-14 | 株式会社シノテスト | ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法 |
| JP5797148B2 (ja) | 2011-09-12 | 2015-10-21 | 富士フイルム株式会社 | コレステリック液晶性混合物、フィルム、選択反射板、積層体および合わせガラス |
| WO2013038696A1 (ja) * | 2011-09-15 | 2013-03-21 | 国立大学法人名古屋大学 | 胸膜中皮腫患者の早期発見のための分子マーカー及びその発現解析方法 |
| WO2013126834A1 (en) * | 2012-02-24 | 2013-08-29 | Children's Hospital Medical Center | Esophageal microrna expression profiles in eosinophilic esophagitis |
| EP2875049B1 (en) | 2012-07-18 | 2018-12-26 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods for preventing and treating chronic kidney disease (ckd) |
| US20160363591A1 (en) * | 2014-01-27 | 2016-12-15 | Medimmune, Llc | Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung |
-
2015
- 2015-02-05 WO PCT/US2015/014652 patent/WO2015120171A1/en not_active Ceased
- 2015-02-05 HK HK17105868.9A patent/HK1232238A1/zh unknown
- 2015-02-05 AU AU2015214103A patent/AU2015214103A1/en not_active Abandoned
- 2015-02-05 WO PCT/US2015/014671 patent/WO2015120185A1/en not_active Ceased
- 2015-02-05 CA CA2936285A patent/CA2936285A1/en not_active Abandoned
- 2015-02-05 SG SG11201606322XA patent/SG11201606322XA/en unknown
- 2015-02-05 RU RU2016135418A patent/RU2016135418A/ru not_active Application Discontinuation
- 2015-02-05 JP JP2016545358A patent/JP2017506064A/ja active Pending
- 2015-02-05 CN CN201580007503.4A patent/CN106164675B/zh not_active Expired - Fee Related
- 2015-02-05 HK HK17105816.2A patent/HK1232290A1/zh unknown
- 2015-02-05 EP EP15706093.0A patent/EP3102951A1/en not_active Withdrawn
- 2015-02-05 KR KR1020167024160A patent/KR20160122756A/ko not_active Withdrawn
- 2015-02-05 MX MX2016009490A patent/MX2016009490A/es unknown
- 2015-02-05 SG SG10201806729VA patent/SG10201806729VA/en unknown
- 2015-02-05 JP JP2016544101A patent/JP6549132B2/ja not_active Expired - Fee Related
- 2015-02-05 MX MX2016009450A patent/MX2016009450A/es unknown
- 2015-02-05 US US15/106,223 patent/US10775388B2/en active Active
- 2015-02-05 BR BR112016017901A patent/BR112016017901A2/pt not_active Application Discontinuation
- 2015-02-05 CA CA2936258A patent/CA2936258A1/en not_active Abandoned
- 2015-02-05 AU AU2015214089A patent/AU2015214089A1/en not_active Abandoned
- 2015-02-05 CN CN201580007504.9A patent/CN106170497A/zh active Pending
- 2015-02-05 US US15/104,502 patent/US9862762B2/en not_active Expired - Fee Related
- 2015-02-05 BR BR112016017926A patent/BR112016017926A2/pt not_active IP Right Cessation
- 2015-02-05 EP EP15706091.4A patent/EP3102601B1/en not_active Not-in-force
- 2015-02-05 KR KR1020167024163A patent/KR20160125409A/ko not_active Withdrawn
- 2015-02-05 RU RU2016135417A patent/RU2016135417A/ru not_active Application Discontinuation
- 2015-02-06 TW TW104104194A patent/TW201542589A/zh unknown
-
2017
- 2017-11-22 US US15/821,716 patent/US20180179272A1/en not_active Abandoned
-
2019
- 2019-07-30 JP JP2019139534A patent/JP2020000236A/ja active Pending
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