JP2017506064A5 - - Google Patents
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- JP2017506064A5 JP2017506064A5 JP2016545358A JP2016545358A JP2017506064A5 JP 2017506064 A5 JP2017506064 A5 JP 2017506064A5 JP 2016545358 A JP2016545358 A JP 2016545358A JP 2016545358 A JP2016545358 A JP 2016545358A JP 2017506064 A5 JP2017506064 A5 JP 2017506064A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- antibody
- derivative
- cell
- number pta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012634 fragment Substances 0.000 claims 22
- 210000004408 hybridoma Anatomy 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 11
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 101001095308 Homo sapiens Periostin Proteins 0.000 claims 2
- 210000000628 antibody-producing cell Anatomy 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 102000048431 human POSTN Human genes 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 241000271566 Aves Species 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 claims 1
- DZBUGLKDJFMEHC-UHFFFAOYSA-O acridine;hydron Chemical compound C1=CC=CC2=CC3=CC=CC=C3[NH+]=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-O 0.000 claims 1
- 210000004102 animal cell Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229910052707 ruthenium Inorganic materials 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461936967P | 2014-02-07 | 2014-02-07 | |
| US61/936,967 | 2014-02-07 | ||
| PCT/US2015/014652 WO2015120171A1 (en) | 2014-02-07 | 2015-02-05 | Novel assay to detect human periostin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019139534A Division JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017506064A JP2017506064A (ja) | 2017-03-02 |
| JP2017506064A5 true JP2017506064A5 (https=) | 2017-08-10 |
Family
ID=52574429
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016545358A Pending JP2017506064A (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2016544101A Expired - Fee Related JP6549132B2 (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2019139534A Pending JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544101A Expired - Fee Related JP6549132B2 (ja) | 2014-02-07 | 2015-02-05 | ヒトペリオスチンを検出する新規アッセイ |
| JP2019139534A Pending JP2020000236A (ja) | 2014-02-07 | 2019-07-30 | ヒトペリオスチンを検出する新規アッセイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10775388B2 (https=) |
| EP (2) | EP3102601B1 (https=) |
| JP (3) | JP2017506064A (https=) |
| KR (2) | KR20160125409A (https=) |
| CN (2) | CN106164675B (https=) |
| AU (2) | AU2015214103A1 (https=) |
| BR (2) | BR112016017901A2 (https=) |
| CA (2) | CA2936285A1 (https=) |
| HK (2) | HK1232290A1 (https=) |
| MX (2) | MX2016009490A (https=) |
| RU (2) | RU2016135417A (https=) |
| SG (2) | SG10201806729VA (https=) |
| TW (1) | TW201542589A (https=) |
| WO (2) | WO2015120171A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3371225A2 (en) | 2015-11-04 | 2018-09-12 | AstraZeneca AB | Dipeptidyl peptidase-4 and periostin as predictors of clinical response to eosinophil-targeted therapeutic agents in eosinophilic diseases |
| WO2018030456A1 (ja) * | 2016-08-10 | 2018-02-15 | 株式会社シノテスト | 試料に含まれるペリオスチンの測定試薬、ペリオスチン測定用前処理剤、ペリオスチン測定方法及びペリオスチン測定の感度の改善方法 |
| WO2018194134A1 (ja) * | 2017-04-20 | 2018-10-25 | 株式会社シノテスト | 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法 |
| WO2019183131A1 (en) * | 2018-03-19 | 2019-09-26 | Bioventures, Llc | Periostin antibodies and methods of using the same |
| CN109879963A (zh) * | 2019-03-15 | 2019-06-14 | 辽宁何氏医学院 | 一种抑制组织器官纤维化和新生血管形成的单克隆抗体及其制备方法和应用 |
| AU2020263592B2 (en) | 2019-04-26 | 2026-03-19 | Cornell University | Klebsiella vaccine and methods of use |
| WO2023127881A1 (ja) * | 2021-12-28 | 2023-07-06 | 積水メディカル株式会社 | 検出方法及び検出試薬 |
| CN115078734A (zh) * | 2022-06-15 | 2022-09-20 | 苏州方达新药开发有限公司 | 一种细胞因子融合蛋白的检测分析方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0832981A1 (en) | 1987-02-17 | 1998-04-01 | Pharming B.V. | DNA sequences to target proteins to the mammary gland for efficient secretion |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| GB0407315D0 (en) | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
| WO2006129672A1 (ja) | 2005-05-30 | 2006-12-07 | Tokyo University Of Science Educational Foundation Administrative Organization | 歯の製造方法、歯の集合体及び組織の製造方法 |
| WO2007045477A2 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Human antibodies against il-13 and therapeutic uses |
| US8017119B2 (en) | 2005-12-28 | 2011-09-13 | Daiichi Sankyo Company, Ltd. | Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved |
| WO2007077934A1 (ja) * | 2005-12-28 | 2007-07-12 | Asubio Pharma Co., Ltd. | 抗ペリオスチン抗体およびそれを含有するペリオスチンが関与する疾患の予防または治療用医薬組成物 |
| KR101560843B1 (ko) | 2007-06-27 | 2015-10-15 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 페리오스틴의 Ｅｘｏｎ-17 부위에 의해 코드되는 펩티드에 대한 항체를 함유하는 암 치료제 |
| BRPI0906261A2 (pt) | 2008-03-31 | 2015-07-07 | Genentech Inc | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" |
| CN102065895A (zh) * | 2008-04-11 | 2011-05-18 | 比奥根艾迪克Ma公司 | 抗-igf-1r抗体和其它化合物的治疗联合 |
| FR2946349B1 (fr) * | 2009-06-03 | 2013-10-04 | Synarc Sas | Sequences, anticorps, procedes et necessaires pour la detection et le dosage in vitro de la periostine, en vue du diagnostic du suivi ou du pronostic de pathologies ou de phenomenes biologiques impliquant la periostine |
| RU2578468C2 (ru) * | 2010-12-16 | 2016-03-27 | Дженентек, Инк. | Способы диагностики и лечения, связанные с ингибированием th2 |
| WO2012158954A1 (en) | 2011-05-18 | 2012-11-22 | Medimmune, Llc | Methods of diagnosing and treating pulmonary diseases or disorders |
| WO2012156513A1 (en) | 2011-05-18 | 2012-11-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for determining whether a subject is at risk of having or developing a chronic kidney disease |
| JP6183809B2 (ja) * | 2011-09-06 | 2017-08-23 | 株式会社シノテスト | ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法 |
| JP5797148B2 (ja) | 2011-09-12 | 2015-10-21 | 富士フイルム株式会社 | コレステリック液晶性混合物、フィルム、選択反射板、積層体および合わせガラス |
| EA201490576A1 (ru) | 2011-09-15 | 2014-09-30 | Нэшенел Юнивёрсити Корпорейшен Нагоя Юнивёрсити | Молекулярный маркер для ранней диагностики мезотелиомы плевры у пациентов и способы для анализа его экспрессии |
| US9260756B2 (en) | 2012-02-24 | 2016-02-16 | Children's Hospital Medical Center | Esophageal microRNA expression profiles in eosinophilic esophagitis |
| PL2875049T3 (pl) * | 2012-07-18 | 2019-07-31 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Sposoby zapobiegania i leczenia przewlekłej choroby nerek (ckd) |
| CA2937387A1 (en) * | 2014-01-27 | 2015-07-30 | Medimmune, Llc | Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung |
-
2015
- 2015-02-05 HK HK17105816.2A patent/HK1232290A1/zh unknown
- 2015-02-05 SG SG10201806729VA patent/SG10201806729VA/en unknown
- 2015-02-05 CN CN201580007503.4A patent/CN106164675B/zh not_active Expired - Fee Related
- 2015-02-05 EP EP15706091.4A patent/EP3102601B1/en not_active Not-in-force
- 2015-02-05 KR KR1020167024163A patent/KR20160125409A/ko not_active Withdrawn
- 2015-02-05 RU RU2016135417A patent/RU2016135417A/ru not_active Application Discontinuation
- 2015-02-05 BR BR112016017901A patent/BR112016017901A2/pt not_active Application Discontinuation
- 2015-02-05 EP EP15706093.0A patent/EP3102951A1/en not_active Withdrawn
- 2015-02-05 HK HK17105868.9A patent/HK1232238A1/zh unknown
- 2015-02-05 SG SG11201606322XA patent/SG11201606322XA/en unknown
- 2015-02-05 JP JP2016545358A patent/JP2017506064A/ja active Pending
- 2015-02-05 KR KR1020167024160A patent/KR20160122756A/ko not_active Withdrawn
- 2015-02-05 WO PCT/US2015/014652 patent/WO2015120171A1/en not_active Ceased
- 2015-02-05 WO PCT/US2015/014671 patent/WO2015120185A1/en not_active Ceased
- 2015-02-05 RU RU2016135418A patent/RU2016135418A/ru not_active Application Discontinuation
- 2015-02-05 CN CN201580007504.9A patent/CN106170497A/zh active Pending
- 2015-02-05 BR BR112016017926A patent/BR112016017926A2/pt not_active IP Right Cessation
- 2015-02-05 US US15/106,223 patent/US10775388B2/en active Active
- 2015-02-05 US US15/104,502 patent/US9862762B2/en not_active Expired - Fee Related
- 2015-02-05 MX MX2016009490A patent/MX2016009490A/es unknown
- 2015-02-05 JP JP2016544101A patent/JP6549132B2/ja not_active Expired - Fee Related
- 2015-02-05 AU AU2015214103A patent/AU2015214103A1/en not_active Abandoned
- 2015-02-05 CA CA2936285A patent/CA2936285A1/en not_active Abandoned
- 2015-02-05 MX MX2016009450A patent/MX2016009450A/es unknown
- 2015-02-05 CA CA2936258A patent/CA2936258A1/en not_active Abandoned
- 2015-02-05 AU AU2015214089A patent/AU2015214089A1/en not_active Abandoned
- 2015-02-06 TW TW104104194A patent/TW201542589A/zh unknown
-
2017
- 2017-11-22 US US15/821,716 patent/US20180179272A1/en not_active Abandoned
-
2019
- 2019-07-30 JP JP2019139534A patent/JP2020000236A/ja active Pending
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