JP2017505302A - トラゾドンおよびその塩酸塩を製造するための改良法 - Google Patents

トラゾドンおよびその塩酸塩を製造するための改良法 Download PDF

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Publication number
JP2017505302A
JP2017505302A JP2016547540A JP2016547540A JP2017505302A JP 2017505302 A JP2017505302 A JP 2017505302A JP 2016547540 A JP2016547540 A JP 2016547540A JP 2016547540 A JP2016547540 A JP 2016547540A JP 2017505302 A JP2017505302 A JP 2017505302A
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JP
Japan
Prior art keywords
compound
chloride
trazodone
hydrochloride
free base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016547540A
Other languages
English (en)
Japanese (ja)
Inventor
シャシカント・カダム
ナレンデル・ラオ・ソミセッティ
スリニバス・アシリ
ナルシムル・ライゴニ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Piramal Enterprises Ltd
Original Assignee
Piramal Enterprises Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piramal Enterprises Ltd filed Critical Piramal Enterprises Ltd
Publication of JP2017505302A publication Critical patent/JP2017505302A/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2016547540A 2014-01-21 2014-12-12 トラゾドンおよびその塩酸塩を製造するための改良法 Pending JP2017505302A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN203/MUM/2014 2014-01-21
PCT/IB2014/066841 WO2015110883A1 (en) 2014-01-21 2014-12-12 An improved process for the preparation of trazodone and hydrochloride salt thereof
IN203MU2014 IN2014MU00203A (enExample) 2014-01-21 2014-12-12

Publications (1)

Publication Number Publication Date
JP2017505302A true JP2017505302A (ja) 2017-02-16

Family

ID=53680891

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016547540A Pending JP2017505302A (ja) 2014-01-21 2014-12-12 トラゾドンおよびその塩酸塩を製造するための改良法

Country Status (6)

Country Link
EP (1) EP3097099A4 (enExample)
JP (1) JP2017505302A (enExample)
CA (1) CA2937417C (enExample)
IL (1) IL246835A0 (enExample)
IN (1) IN2014MU00203A (enExample)
WO (1) WO2015110883A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL234822B1 (pl) 2017-03-14 2020-04-30 Politechnika Krakowska Im Tadeusza Kosciuszki Sposób otrzymywania trazodonu
CN117517545A (zh) * 2023-12-08 2024-02-06 重庆锐恩医药有限公司 一种盐酸曲唑酮有关物质检测方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3381009A (en) * 1965-12-15 1968-04-30 Acraf Triazole-(4,3-a)-pyridines
WO2009105604A1 (en) * 2008-02-20 2009-08-27 Auspex Pharmaceuticals, Inc. Substituted triazolopyridines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4252806A (en) * 1979-09-24 1981-02-24 Mead Johnson & Company Triazoloquinolones
HU201324B (en) * 1988-07-29 1990-10-28 Egyt Gyogyszervegyeszeti Gyar New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on
ITMI20071603A1 (it) * 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3381009A (en) * 1965-12-15 1968-04-30 Acraf Triazole-(4,3-a)-pyridines
WO2009105604A1 (en) * 2008-02-20 2009-08-27 Auspex Pharmaceuticals, Inc. Substituted triazolopyridines

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AICHE JOURNAL, vol. 44, no. 3, JPN6018029771, 1998, pages 612 - 646, ISSN: 0004023061 *
JOURNAL OF CHEMICAL AND PHARMACEUTICAL RESEARCH, vol. 2, no. 1, JPN6018029765, 2010, pages 458 - 472, ISSN: 0004023059 *
JOURNAL OF ORGANIC CHEMISTRY, vol. 39, no. 23, JPN6018029767, 1974, pages 3416 - 3418, ISSN: 0004023060 *
化学大辞典３ 縮刷版, JPN6019014615, 15 September 1963 (1963-09-15), pages 938 - 939, ISSN: 0004153184 *
標準化学用語辞典, JPN6019014614, 30 March 1991 (1991-03-30), pages 348 - 349, ISSN: 0004153183 *

Also Published As

Publication number Publication date
IN2014MU00203A (enExample) 2015-09-25
EP3097099A1 (en) 2016-11-30
EP3097099A4 (en) 2017-08-23
IL246835A0 (en) 2016-08-31
WO2015110883A1 (en) 2015-07-30
CA2937417C (en) 2022-04-12
CA2937417A1 (en) 2015-07-30

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