JP2017502020A5 - - Google Patents
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- Publication number
- JP2017502020A5 JP2017502020A5 JP2016540644A JP2016540644A JP2017502020A5 JP 2017502020 A5 JP2017502020 A5 JP 2017502020A5 JP 2016540644 A JP2016540644 A JP 2016540644A JP 2016540644 A JP2016540644 A JP 2016540644A JP 2017502020 A5 JP2017502020 A5 JP 2017502020A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- formula
- compound
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C1=CC2C(Cc3n[n]nn3)(CN)CC2C1 Chemical compound *C1=CC2C(Cc3n[n]nn3)(CN)CC2C1 0.000 description 9
- XZGLNCKSNVGDNX-UHFFFAOYSA-N Cc1n[nH]nn1 Chemical compound Cc1n[nH]nn1 XZGLNCKSNVGDNX-UHFFFAOYSA-N 0.000 description 3
- ZTKAJVXFDWQBSJ-UHFFFAOYSA-N CCC1=CC2C(CC(N3)=NOC3=O)(CN)CC2C1 Chemical compound CCC1=CC2C(CC(N3)=NOC3=O)(CN)CC2C1 ZTKAJVXFDWQBSJ-UHFFFAOYSA-N 0.000 description 1
- ZMRQKZANSRISRS-UHFFFAOYSA-N CCC1=CC2C(Cc3nnn[nH]3)(CN)CC2C1 Chemical compound CCC1=CC2C(Cc3nnn[nH]3)(CN)CC2C1 ZMRQKZANSRISRS-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917623P | 2013-12-18 | 2013-12-18 | |
| US61/917,623 | 2013-12-18 | ||
| PCT/EP2014/077937 WO2015091463A1 (en) | 2013-12-18 | 2014-12-16 | Gamma-aminobutyric acid (gaba) analogues for the treatment of pain and other disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502020A JP2017502020A (ja) | 2017-01-19 |
| JP2017502020A5 true JP2017502020A5 (enExample) | 2018-02-01 |
| JP6491213B2 JP6491213B2 (ja) | 2019-03-27 |
Family
ID=52278595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540644A Expired - Fee Related JP6491213B2 (ja) | 2013-12-18 | 2014-12-16 | 疼痛および他の障害の治療のためのガンマ−アミノ酪酸（ｇａｂａ）類似体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9663479B2 (enExample) |
| EP (1) | EP3083572B1 (enExample) |
| JP (1) | JP6491213B2 (enExample) |
| KR (1) | KR102031334B1 (enExample) |
| CN (2) | CN105899495B (enExample) |
| AU (1) | AU2014364693B2 (enExample) |
| CA (1) | CA2932050C (enExample) |
| RU (1) | RU2679407C1 (enExample) |
| WO (1) | WO2015091463A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2932050C (en) * | 2013-12-18 | 2023-09-26 | Novassay Sa | Gamma-aminobutyric acid (gaba) analogues for the treatment of pain and other disorders |
| US10150723B2 (en) * | 2015-05-27 | 2018-12-11 | Novassay S.A. | Separation of enantiomers of 3-ethylbicyclo[3.2.0]hept-3-en-6-one |
| CN110818582B (zh) * | 2019-11-20 | 2023-06-09 | 合肥拓锐生物科技有限公司 | 一种gaba类似物及其盐，及其合成方法、应用、药物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994022868A1 (en) * | 1993-04-01 | 1994-10-13 | University Of Virginia | 7-azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents |
| DE19508459A1 (de) * | 1995-03-09 | 1996-09-12 | Wacker Chemie Gmbh | Verfahren zur Herstellung von Alkylsilanen mit sperrigen Alkylresten |
| US6518289B1 (en) * | 1997-12-16 | 2003-02-11 | Pfizer, Inc. | 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
| US6620829B2 (en) * | 2000-10-17 | 2003-09-16 | Warner-Lambert Company | Method of treating noninflammatory cartilage damage |
| AU2004271800A1 (en) * | 2003-09-12 | 2005-03-24 | Pfizer Inc. | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
| EP2657219B1 (en) * | 2007-09-28 | 2014-12-10 | Daiichi Sankyo Company, Limited | Intermediate for producing bicyclic y-amino acid derivative |
| WO2010079668A1 (ja) | 2009-01-08 | 2010-07-15 | 第一三共株式会社 | オレフィン化合物 |
| JP5557292B2 (ja) | 2009-03-26 | 2014-07-23 | 第一三共株式会社 | 二環性γ−アミノ酸誘導体の製造方法 |
| JPWO2014030743A1 (ja) * | 2012-08-24 | 2016-08-08 | 武田薬品工業株式会社 | 複素環化合物 |
| TWI635071B (zh) * | 2013-07-08 | 2018-09-11 | 第一三共股份有限公司 | 光學活性二環γ－胺基酸衍生物及其製造方法 |
| CA2932050C (en) * | 2013-12-18 | 2023-09-26 | Novassay Sa | Gamma-aminobutyric acid (gaba) analogues for the treatment of pain and other disorders |
-
2014
- 2014-12-16 CA CA2932050A patent/CA2932050C/en active Active
- 2014-12-16 RU RU2016128012A patent/RU2679407C1/ru active
- 2014-12-16 AU AU2014364693A patent/AU2014364693B2/en active Active
- 2014-12-16 CN CN201480069317.9A patent/CN105899495B/zh active Active
- 2014-12-16 US US15/106,139 patent/US9663479B2/en active Active - Reinstated
- 2014-12-16 EP EP14821571.8A patent/EP3083572B1/en active Active
- 2014-12-16 KR KR1020167019522A patent/KR102031334B1/ko active Active
- 2014-12-16 JP JP2016540644A patent/JP6491213B2/ja not_active Expired - Fee Related
- 2014-12-16 WO PCT/EP2014/077937 patent/WO2015091463A1/en not_active Ceased
- 2014-12-16 CN CN201910061968.8A patent/CN109721562A/zh active Pending
-
2016
- 2016-11-22 US US15/359,120 patent/US9750720B2/en active Active
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