JP2017501227A - アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法 - Google Patents

アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法 Download PDF

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JP2017501227A
JP2017501227A JP2016560871A JP2016560871A JP2017501227A JP 2017501227 A JP2017501227 A JP 2017501227A JP 2016560871 A JP2016560871 A JP 2016560871A JP 2016560871 A JP2016560871 A JP 2016560871A JP 2017501227 A JP2017501227 A JP 2017501227A
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acid
alginic acid
residue
molecular weight
composition according
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JP2017501227A5 (US20070167479A1-20070719-C00034.png
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ガスリー,ウェンデル
ハーン,ゲイリー
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エヴォフェム,インク.
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Publication of JP2017501227A publication Critical patent/JP2017501227A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/02Contraceptive devices; Pessaries; Applicators therefor for use by males
    • A61F6/04Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/065Condom-like devices worn by females
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734Alginic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00Devices for applying media, e.g. remedies, on the human body
    • A61M35/003Portable hand-held applicators having means for dispensing or spreading integral media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016560871A 2013-12-19 2014-12-19 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法 Pending JP2017501227A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361918445P 2013-12-19 2013-12-19
US61/918,445 2013-12-19
PCT/US2014/071664 WO2015095793A1 (en) 2013-12-19 2014-12-19 Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound

Related Child Applications (1)

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JP2020063444A Division JP2020125298A (ja) 2013-12-19 2020-03-31 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法

Publications (2)

Publication Number Publication Date
JP2017501227A true JP2017501227A (ja) 2017-01-12
JP2017501227A5 JP2017501227A5 (US20070167479A1-20070719-C00034.png) 2017-12-07

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JP2016560871A Pending JP2017501227A (ja) 2013-12-19 2014-12-19 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
JP2020063444A Pending JP2020125298A (ja) 2013-12-19 2020-03-31 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
JP2022017393A Pending JP2022070924A (ja) 2013-12-19 2022-02-07 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法

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JP2020063444A Pending JP2020125298A (ja) 2013-12-19 2020-03-31 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
JP2022017393A Pending JP2022070924A (ja) 2013-12-19 2022-02-07 アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法

Country Status (15)

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US (2) US11337989B2 (US20070167479A1-20070719-C00034.png)
EP (2) EP3735966A1 (US20070167479A1-20070719-C00034.png)
JP (3) JP2017501227A (US20070167479A1-20070719-C00034.png)
KR (1) KR102407408B1 (US20070167479A1-20070719-C00034.png)
CN (2) CN114452298A (US20070167479A1-20070719-C00034.png)
AU (2) AU2014368971B2 (US20070167479A1-20070719-C00034.png)
BR (1) BR112016014506B1 (US20070167479A1-20070719-C00034.png)
DK (1) DK3082826T3 (US20070167479A1-20070719-C00034.png)
ES (1) ES2790703T3 (US20070167479A1-20070719-C00034.png)
IL (1) IL246146B2 (US20070167479A1-20070719-C00034.png)
MX (2) MX2016008023A (US20070167479A1-20070719-C00034.png)
NZ (1) NZ722215A (US20070167479A1-20070719-C00034.png)
RU (1) RU2691950C1 (US20070167479A1-20070719-C00034.png)
WO (1) WO2015095793A1 (US20070167479A1-20070719-C00034.png)
ZA (1) ZA201604862B (US20070167479A1-20070719-C00034.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2014008149A0 (en) 2012-06-13 2014-12-31 Evofem Inc Compositions and methods for enhancing the efficacy of contraceptive microbicides
RU2691950C1 (ru) 2013-12-19 2019-06-19 Ивофем, Инк. Композиции и способы ингибирования воспаления и заболеваний с применением антимикробного соединения на основе альгиновой кислоты
DE102017110168A1 (de) 2016-05-25 2017-11-30 Samsung Electronics Co., Ltd. Elektronische Vorrichtung mit NFC-Antenne
WO2018049326A1 (en) * 2016-09-12 2018-03-15 Evofem Biosciences, Inc. Combination gel for sexually transmitted infections
AU2017338748A1 (en) * 2016-10-04 2019-05-02 Evofem Inc. Method of treatment and prevention of bacterial vaginosis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06172375A (ja) * 1992-12-04 1994-06-21 Kibun Food Chemifa Co Ltd オリゴマンヌロン酸を重合度によって分離する方法
WO2001066084A2 (en) * 2000-03-07 2001-09-13 Rush-Presbyterian-St. Luke's Medical Center Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa
WO2004011032A1 (ja) * 2002-07-26 2004-02-05 Mikasa Seiyaku Co., Ltd. 外用剤
JP6352907B2 (ja) * 2012-06-13 2018-07-04 イボフェム, インコーポレイテッド 避妊殺菌剤の効果を増強するための組成物および方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213323B (it) 1986-08-07 1989-12-20 Crinos Industria Farmaco Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida
US4999342A (en) 1988-08-16 1991-03-12 Ortho Pharmaceutical Corporation Long lasting contraceptive suppository composition and methods of use
US5592949A (en) 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
US5667492A (en) 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
FR2728464B1 (fr) 1994-12-22 1997-04-30 Innothera Lab Sa Forme galenique unitaire, son procede d'obtention et ses utilisations
US6093394A (en) 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
AU1661901A (en) 1999-11-24 2001-06-04 Cargill Dow Llc Improved lactic acid processing; methods; arrangements; and, products
JP2009102407A (ja) * 2001-03-08 2009-05-14 Rohto Pharmaceut Co Ltd Gリッチなアルギン酸含有組成物
US20020177624A1 (en) 2001-03-16 2002-11-28 Calvin Hanna Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis
ITMI20010913A1 (it) 2001-05-04 2002-11-04 Univ Pavia Composizioni a rilascio controllato di acido lattico a livello vaginale
JP2004537525A (ja) * 2001-06-11 2004-12-16 メルク エンド カムパニー インコーポレーテッド PPARδアゴニストの投与による炎症性疾患の治療法
US20130150810A1 (en) 2002-04-30 2013-06-13 The Population Council, Inc. Intravaginal ring for the delivery of unique combinations of antimicrobial compositions
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
BRPI0411429A (pt) 2003-06-13 2006-07-25 Idh Holding Aps tratamento de sintomas associados com vaginose bacteriana
US20050272700A1 (en) 2004-05-10 2005-12-08 Servet Buyuktimkin Topical treatment and prevention of human papilloma virus (HPV) infection
RU2257197C1 (ru) * 2004-05-12 2005-07-27 Дулькис Мария Дмитриевна Вагинальные суппозитории, обладающие контрацептивным действием
UA93354C2 (ru) 2004-07-09 2011-02-10 Гилиад Сайенсиз, Инк. Местный противовирусный препарат
BRPI0718707A2 (pt) * 2006-11-10 2014-01-07 Rohto Pharma Composição para aplicação em pele ou em mucosa
US7659259B2 (en) 2006-12-21 2010-02-09 Bausch & Lomb Incorporated Method of treating inflammation of the eye
JP5409596B2 (ja) 2007-03-30 2014-02-05 ラキュアー エービー 婦人科の障害の治療における乳酸オリゴマーの使用
WO2008148018A2 (en) 2007-05-24 2008-12-04 New York Blood Center Inc. Rapidly dispersible vaginal tablet that provides a bioadhesive gel
TW200927141A (en) 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
US20110104262A1 (en) 2008-04-16 2011-05-05 Cipla Limited Topical Combinations Comprising an Antimycotic Agent and an Antiviral Agent
WO2009155118A1 (en) * 2008-05-30 2009-12-23 Reprotect, Inc. Compositions and methods for inactivation of pathogens at genital tract surfaces
EP2130531A1 (en) 2008-06-04 2009-12-09 Rolf Kullgren AB Vaginal suppository comprising lactic acid
EP2440560A1 (en) 2009-06-10 2012-04-18 Ultimorphix Technologies B.v. The succinate of tenofovir disoproxil
AR086249A1 (es) 2011-05-02 2013-11-27 Aptalis Pharmatech Inc Composiciones de tabletas de disolucion rapida de administracion vaginal
AU2012275292B2 (en) 2011-06-28 2015-11-12 Chemo Research, S.L. High dosage mucoadhesive metronidazole aqueous-based gel formulations their use to treat bacterial vaginosis
WO2015027071A1 (en) 2013-08-21 2015-02-26 Georgia Regents Research Institute, Inc. Gpr81 agonists and methods thereof for promoting production of secretory iga
RU2691950C1 (ru) 2013-12-19 2019-06-19 Ивофем, Инк. Композиции и способы ингибирования воспаления и заболеваний с применением антимикробного соединения на основе альгиновой кислоты
US9801839B2 (en) 2014-02-28 2017-10-31 Macfarlane Burnet Institute For Medical Research And Public Health Pty Ltd Therapeutic method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06172375A (ja) * 1992-12-04 1994-06-21 Kibun Food Chemifa Co Ltd オリゴマンヌロン酸を重合度によって分離する方法
WO2001066084A2 (en) * 2000-03-07 2001-09-13 Rush-Presbyterian-St. Luke's Medical Center Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa
WO2004011032A1 (ja) * 2002-07-26 2004-02-05 Mikasa Seiyaku Co., Ltd. 外用剤
JP6352907B2 (ja) * 2012-06-13 2018-07-04 イボフェム, インコーポレイテッド 避妊殺菌剤の効果を増強するための組成物および方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Biology of mucosally transmitted sexual infection -Translating the basic science into novel HIV inte", AIDS RESEARCH AND HUMAN RETROVIRUSES, vol. 28(11), JPN7019000398, 11 November 2012 (2012-11-11), pages 1389 - 1396, ISSN: 0004185122 *
"Inhibitory effect of alginic acids on hyaluronidase and on histamine release from mast cells", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 61(6), JPN6019004859, 23 June 1997 (1997-06-23), pages 1030 - 1032, ISSN: 0004185121 *
DEREK H. OWEN. ET AL.: "Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus", JOURNAL OF CONTROLLED RELEASE, vol. 60, JPN6018025509, 1999, pages 23 - 34, XP004170488, ISSN: 0003977787, DOI: 10.1016/S0168-3659(99)00017-6 *

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RU2016129069A (ru) 2018-01-23
KR102407408B1 (ko) 2022-06-10
EP3735966A1 (en) 2020-11-11
AU2020202835A1 (en) 2020-05-21
BR112016014506A2 (pt) 2017-10-31
US20220241301A1 (en) 2022-08-04
DK3082826T3 (da) 2020-05-04
ES2790703T3 (es) 2020-10-28
IL246146B1 (en) 2023-11-01
AU2014368971B2 (en) 2020-02-06
AU2020202835B2 (en) 2021-12-02
JP2022070924A (ja) 2022-05-13
MX2021001742A (es) 2021-04-19
IL246146B2 (en) 2024-03-01
KR20160103036A (ko) 2016-08-31
JP2020125298A (ja) 2020-08-20
EP3082826A4 (en) 2017-08-23
US20160354394A1 (en) 2016-12-08
IL246146A0 (en) 2016-07-31
EP3082826A1 (en) 2016-10-26
CN114452298A (zh) 2022-05-10
BR112016014506B1 (pt) 2022-06-28
EP3082826B1 (en) 2020-03-11
RU2691950C1 (ru) 2019-06-19
NZ722215A (en) 2019-02-22
WO2015095793A1 (en) 2015-06-25
CN106029078A (zh) 2016-10-12
ZA201604862B (en) 2017-08-30
MX2016008023A (es) 2017-01-13
US11337989B2 (en) 2022-05-24
AU2014368971A1 (en) 2016-07-28

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