JP2017501211A5 - - Google Patents
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- Publication number
- JP2017501211A5 JP2017501211A5 JP2016552481A JP2016552481A JP2017501211A5 JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5 JP 2016552481 A JP2016552481 A JP 2016552481A JP 2016552481 A JP2016552481 A JP 2016552481A JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- chain variable
- variable region
- antibody
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361900942P | 2013-11-06 | 2013-11-06 | |
| US61/900,942 | 2013-11-06 | ||
| US201462054324P | 2014-09-23 | 2014-09-23 | |
| US62/054,324 | 2014-09-23 | ||
| US201462064380P | 2014-10-15 | 2014-10-15 | |
| US62/064,380 | 2014-10-15 | ||
| PCT/US2014/064327 WO2015069880A1 (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Division JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017501211A JP2017501211A (ja) | 2017-01-12 |
| JP2017501211A5 true JP2017501211A5 (Direct) | 2017-11-24 |
Family
ID=53042071
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552481A Pending JP2017501211A (ja) | 2013-11-06 | 2014-11-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9822172B2 (Direct) |
| EP (2) | EP3556863B1 (Direct) |
| JP (4) | JP2017501211A (Direct) |
| KR (1) | KR102404285B1 (Direct) |
| CN (1) | CN105793439B (Direct) |
| AU (1) | AU2014346695B2 (Direct) |
| BR (1) | BR112016010106A2 (Direct) |
| CA (2) | CA2929547C (Direct) |
| EA (1) | EA201690731A1 (Direct) |
| HK (1) | HK1221490A1 (Direct) |
| MX (1) | MX375701B (Direct) |
| WO (1) | WO2015069880A1 (Direct) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009308497B2 (en) | 2008-10-21 | 2014-10-23 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EA201290387A1 (ru) | 2009-12-20 | 2013-02-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US10935548B2 (en) | 2011-12-08 | 2021-03-02 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2 |
| TR201807542T4 (tr) | 2013-01-17 | 2018-06-21 | Astute Medical Inc | Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler. |
| US10300108B2 (en) | 2013-12-03 | 2019-05-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| BR112017005554A2 (en) * | 2014-10-29 | 2018-01-23 | F. Hoffmann-La Roche Ag | methods for predicting a subject's risk of rapid progression to chronic heart failure and uses of at least one biomarker and at least one binding agent |
| EP3281011B1 (en) | 2015-04-09 | 2024-06-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3359966B1 (en) * | 2015-10-08 | 2020-01-01 | Roche Diagnostics GmbH | Igfbp7 for prediction of risk of aki when measured prior to surgery |
| US11243217B2 (en) | 2016-06-06 | 2022-02-08 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| WO2018145117A1 (en) | 2017-02-06 | 2018-08-09 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2018187453A1 (en) | 2017-04-05 | 2018-10-11 | Astute Medical, Inc. | Assays for timp2 having improved performance in biological samples |
| US11435364B2 (en) | 2018-05-24 | 2022-09-06 | Renibus Therapeutics, Inc. | Methods of treating patients at risk for renal injury and renal failure |
| WO2020234482A1 (en) * | 2019-05-21 | 2020-11-26 | Universität Zürich | MAPKi RESISTANCE SIGNATURES |
| KR102533791B1 (ko) * | 2022-09-15 | 2023-05-18 | 경북대학교 산학협력단 | 비색법 신호형질 복합체, 이를 이용하는 신장질환 진단용 키트 및 진단법 |
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| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DK0463151T3 (da) | 1990-01-12 | 1996-07-01 | Cell Genesys Inc | Frembringelse af xenogene antistoffer |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| US5166051A (en) | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69127627T2 (de) | 1990-08-29 | 1998-02-19 | Genpharm Int | Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| JPH05504841A (ja) | 1990-09-14 | 1993-07-22 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途 |
| GB9109645D0 (en) | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| EP0585310B1 (en) | 1991-04-10 | 1999-03-17 | Biosite Diagnostics Inc. | Crosstalk inhibitors and their uses |
| AU1911592A (en) | 1991-04-10 | 1992-11-17 | Biosite Diagnostics Incorporated | Novel conjugates and assays for simultaneous detection of multiple ligands |
| DE69233254T2 (de) | 1991-06-14 | 2004-09-16 | Genentech, Inc., South San Francisco | Humanisierter Heregulin Antikörper |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| KR100654645B1 (ko) | 1995-04-27 | 2007-04-04 | 아브게닉스, 인크. | 면역화된 제노마우스 유래의 인간 항체 |
| AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6391265B1 (en) | 1996-08-26 | 2002-05-21 | Biosite Diagnostics, Inc. | Devices incorporating filters for filtering fluid samples |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| JP4215172B2 (ja) | 1996-12-03 | 2009-01-28 | アムジェン フレモント インク． | 複数のＶ▲下Ｈ▼およびＶ▲下κ▼領域を含むヒトＩｇ遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体 |
| US6045899A (en) | 1996-12-12 | 2000-04-04 | Usf Filtration & Separations Group, Inc. | Highly assymetric, hydrophilic, microfiltration membranes having large pore diameters |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| US7109030B2 (en) * | 2000-03-31 | 2006-09-19 | Nuvelo, Inc. | Methods of therapy and diagnosis using insulin-like growth factor binding protein-like polypeptides and polynucleotides |
| US20020132983A1 (en) | 2000-11-30 | 2002-09-19 | Junghans Richard P. | Antibodies as chimeric effector cell receptors against tumor antigens |
| WO2006119203A2 (en) * | 2005-04-29 | 2006-11-09 | Beckman Coulter | Fluorescence lateral flow immunoassay |
| BRPI0613387A2 (pt) | 2005-07-08 | 2011-01-11 | Biogen Idec Inc | anticorpo isolado ou fragmento de ligação de antìgeno deste e o seu uso, polinucleotìdeo isolado, composição, vetor, célula hospedeira, anticorpo anti-sp35 e método para a produção do mesmo, polipeptìdeo isolado, método in vitro para redução da inibição do crescimento axonal e método in vitro para inibição do crescimento do colapso do cone |
| WO2008089994A1 (en) * | 2007-01-25 | 2008-07-31 | Roche Diagnostics Gmbh | Use of igfbp-7 in the assessment of heart failure |
| US9164097B2 (en) * | 2008-10-14 | 2015-10-20 | National Research Council Of Canada | Formulations targeting IGFBP7 for diagnosis and therapy of cancer |
| MX2011011670A (es) | 2009-05-01 | 2011-11-18 | Abbott Lab | Inmunoglobulinas de dominio variable dual y usos de las mismas. |
| EA201290387A1 (ru) | 2009-12-20 | 2013-02-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| ES2585184T3 (es) * | 2010-02-05 | 2016-10-04 | Astute Medical, Inc. | Procedimientos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| US20130224191A1 (en) | 2010-08-27 | 2013-08-29 | Robert A. Stull | Notum protein modulators and methods of use |
| AU2012332193A1 (en) * | 2011-11-03 | 2014-05-15 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of T-cell responses |
-
2014
- 2014-11-06 CA CA2929547A patent/CA2929547C/en active Active
- 2014-11-06 US US15/035,205 patent/US9822172B2/en active Active
- 2014-11-06 JP JP2016552481A patent/JP2017501211A/ja active Pending
- 2014-11-06 CA CA3185700A patent/CA3185700A1/en active Pending
- 2014-11-06 AU AU2014346695A patent/AU2014346695B2/en active Active
- 2014-11-06 HK HK16109610.3A patent/HK1221490A1/zh unknown
- 2014-11-06 EA EA201690731A patent/EA201690731A1/ru unknown
- 2014-11-06 KR KR1020167014700A patent/KR102404285B1/ko active Active
- 2014-11-06 EP EP19158290.7A patent/EP3556863B1/en active Active
- 2014-11-06 CN CN201480066318.8A patent/CN105793439B/zh active Active
- 2014-11-06 MX MX2016005834A patent/MX375701B/es active IP Right Grant
- 2014-11-06 BR BR112016010106A patent/BR112016010106A2/pt not_active Application Discontinuation
- 2014-11-06 EP EP14860878.9A patent/EP3066221A4/en not_active Withdrawn
- 2014-11-06 WO PCT/US2014/064327 patent/WO2015069880A1/en not_active Ceased
-
2017
- 2017-11-20 US US15/818,669 patent/US10562961B2/en active Active
-
2019
- 2019-11-25 JP JP2019212462A patent/JP2020048569A/ja active Pending
-
2020
- 2020-01-17 US US16/745,781 patent/US20200247879A1/en not_active Abandoned
-
2022
- 2022-01-13 JP JP2022003920A patent/JP7277623B2/ja active Active
-
2023
- 2023-01-06 JP JP2023000938A patent/JP2023052239A/ja active Pending
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