JP2017500279A5 - - Google Patents
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- JP2017500279A5 JP2017500279A5 JP2016523932A JP2016523932A JP2017500279A5 JP 2017500279 A5 JP2017500279 A5 JP 2017500279A5 JP 2016523932 A JP2016523932 A JP 2016523932A JP 2016523932 A JP2016523932 A JP 2016523932A JP 2017500279 A5 JP2017500279 A5 JP 2017500279A5
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- JP
- Japan
- Prior art keywords
- channel
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- impedance
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- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361891758P | 2013-10-16 | 2013-10-16 | |
| US61/891,758 | 2013-10-16 | ||
| PCT/US2014/060961 WO2015057998A1 (en) | 2013-10-16 | 2014-10-16 | Device for formulating particles at small volumes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017500279A JP2017500279A (ja) | 2017-01-05 |
| JP2017500279A5 true JP2017500279A5 (https=) | 2017-11-09 |
| JP6640079B2 JP6640079B2 (ja) | 2020-02-05 |
Family
ID=52828708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016523932A Active JP6640079B2 (ja) | 2013-10-16 | 2014-10-16 | 小容積の粒子を調製するためのデバイス及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10159652B2 (https=) |
| EP (1) | EP3057693A4 (https=) |
| JP (1) | JP6640079B2 (https=) |
| CN (1) | CN105813721B (https=) |
| CA (1) | CA2927358C (https=) |
| WO (1) | WO2015057998A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016138175A1 (en) | 2015-02-24 | 2016-09-01 | The University Of British Columbia | Continuous flow microfluidic system |
| EP4353257A3 (en) | 2015-04-13 | 2024-08-07 | CureVac Manufacturing GmbH | Method for producing rna compositions |
| USD771833S1 (en) | 2015-04-28 | 2016-11-15 | University Of British Columbia | Microfluidic cartridge |
| USD771834S1 (en) | 2015-04-28 | 2016-11-15 | University Of British Columbia | Microfluidic cartridge |
| EP3288671A4 (en) | 2015-04-28 | 2019-01-16 | The University Of British Columbia | DISPOSABLE MICROFLUIDIC CARTRIDGE |
| USD772427S1 (en) | 2015-04-28 | 2016-11-22 | University Of British Columbia | Microfluidic cartridge |
| WO2017048770A1 (en) * | 2015-09-15 | 2017-03-23 | Regulus Therapeutics, Inc. | Systems, compositions, and methods for formulating nucleic acid compositions |
| EP3400097B1 (en) | 2016-01-06 | 2021-01-27 | The University Of British Columbia | Bifurcating mixers and methods of their use and manufacture |
| KR102447457B1 (ko) | 2016-07-06 | 2022-09-27 | 프레시젼 나노시스템스 유엘씨 | 지능형 미세 유체 혼합 기기 및 카트리지 |
| WO2018064755A1 (en) * | 2016-10-03 | 2018-04-12 | Precision Nanosystems Inc. | Compositions for transfecting resistant cell types |
| EP3554478B1 (en) * | 2016-12-16 | 2022-01-26 | Delphi Scientific, LLC | Layered particles and processes thereof |
| WO2019139997A1 (en) * | 2018-01-09 | 2019-07-18 | Trucode Gene Repair, Inc. | Polymer-based nanoparticles, related formulation methods, and apparatus |
| US11679159B2 (en) | 2018-04-29 | 2023-06-20 | Precision NanoSystems ULC | Compositions for transfecting resistant cell types |
| CA3112837A1 (en) * | 2018-10-19 | 2020-04-23 | Translate Bio, Inc. | Pumpless encapsulation of messenger rna |
| KR102732019B1 (ko) * | 2019-04-15 | 2024-11-20 | 글로벌 라이프 사이언시즈 솔루션즈 캐나다 유엘씨 | T 세포 유전자 발현의 비바이러스 변형 |
| WO2021133765A1 (en) * | 2019-12-23 | 2021-07-01 | Nutcracker Therapeutics, Inc. | Microfluidic apparatus and methods of use thereof |
| US12194157B2 (en) | 2020-04-09 | 2025-01-14 | Finncure Oy | Carrier for targeted delivery to a host |
| FI20215508A1 (en) | 2020-04-09 | 2021-10-10 | Niemelae Erik Johan | Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection |
| DE102020214601A1 (de) * | 2020-11-19 | 2022-05-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Verfahren und Vorrichtung zur Herstellung einer Flüssigkeit enthaltend Liposomen und hergestellte Flüssigkeit |
| US20240100492A1 (en) | 2020-11-30 | 2024-03-28 | Andre Wild | Non aggregating microfluidic mixer and methods therefor |
| WO2023081546A1 (en) * | 2021-11-05 | 2023-05-11 | Verily Life Sciences Llc | Methods and systems for point-of-care synthesis and administration of particle-based therapeutics |
| CN114247398A (zh) * | 2021-12-17 | 2022-03-29 | 沈磊 | 一种脂质纳米颗粒制备系统及设备 |
| WO2024006863A1 (en) | 2022-06-30 | 2024-01-04 | Precision NanoSystems ULC | Lipid nanoparticle formulations for vaccines |
| JP2026500252A (ja) | 2022-12-12 | 2026-01-06 | グローバル・ライフ・サイエンシズ・ソリューションズ・カナダ・ユーエルシー | 脂質ナノ粒子の凍結乾燥方法及び組成物 |
| CN121443279A (zh) | 2023-06-28 | 2026-01-30 | 环球生命科学解决方案加拿大有限公司 | 用于细胞疗法的脂质纳米颗粒制剂和相关方法 |
| CN121752251A (zh) | 2023-08-31 | 2026-03-27 | 环球生命科学解决方案加拿大有限公司 | 用于肺部递送纳米颗粒的鼻内制剂、组合物、用途及其制造方法 |
| WO2025219528A1 (en) | 2024-04-17 | 2025-10-23 | Global Life Sciences Solutions Canada Ulc | Non-destructive plasmid delivery to immune cells |
| WO2025219491A1 (en) | 2024-04-17 | 2025-10-23 | Global Life Sciences Solutions Canada Ulc | Method and composition for hdr template dna delivery |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| WO1992001704A1 (en) | 1990-07-26 | 1992-02-06 | Koichi Shudo | Oligodeoxyribonucleotides |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US5719262A (en) | 1993-11-22 | 1998-02-17 | Buchardt, Deceased; Ole | Peptide nucleic acids having amino acid side chains |
| US5766855A (en) | 1991-05-24 | 1998-06-16 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity and sequence specificity |
| US5641625A (en) | 1992-05-22 | 1997-06-24 | Isis Pharmaceuticals, Inc. | Cleaving double-stranded DNA with peptide nucleic acids |
| US5714331A (en) | 1991-05-24 | 1998-02-03 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility |
| DK51092D0 (da) | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| GB9211979D0 (en) | 1992-06-05 | 1992-07-15 | Buchard Ole | Uses of nucleic acid analogues |
| US5417956A (en) * | 1992-08-18 | 1995-05-23 | Worcester Polytechnic Institute | Preparation of nanophase solid state materials |
| US5527675A (en) | 1993-08-20 | 1996-06-18 | Millipore Corporation | Method for degradation and sequencing of polymers which sequentially eliminate terminal residues |
| DE4331012A1 (de) | 1993-09-13 | 1995-03-16 | Bayer Ag | Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik |
| GB2284209A (en) | 1993-11-25 | 1995-05-31 | Ole Buchardt | Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5705333A (en) | 1994-08-05 | 1998-01-06 | The Regents Of The University Of California | Peptide-based nucleic acid mimics(PENAMS) |
| US5753789A (en) | 1996-07-26 | 1998-05-19 | Yale University | Oligonucleotides containing L-nucleosides |
| ES2192672T3 (es) | 1996-11-18 | 2003-10-16 | Takeshi Imanishi | Nuevos analogos de nucleotidos. |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US6251666B1 (en) | 1997-03-31 | 2001-06-26 | Ribozyme Pharmaceuticals, Inc. | Nucleic acid catalysts comprising L-nucleotide analogs |
| US6107470A (en) | 1997-05-29 | 2000-08-22 | Nielsen; Peter E. | Histidine-containing peptide nucleic acids |
| JP4236812B2 (ja) | 1997-09-12 | 2009-03-11 | エクシコン エ／エス | オリゴヌクレオチド類似体 |
| AU4965499A (en) | 1998-07-09 | 2000-02-01 | Biocept, Inc. | Method of using an improved peptide nucleic acid universal library to optimize dna sequence hybridation |
| JP2002026134A (ja) | 2000-07-12 | 2002-01-25 | Seiko Epson Corp | 半導体集積回路の製造方法及びこの方法により製造した半導体集積回路 |
| EP1412065A2 (en) | 2001-07-27 | 2004-04-28 | President And Fellows Of Harvard College | Laminar mixing apparatus and methods |
| GB0126716D0 (en) | 2001-11-07 | 2002-01-02 | Advanced Phytonics Ltd | Method for the production of particles |
| JP3775305B2 (ja) * | 2002-01-31 | 2006-05-17 | コニカミノルタホールディングス株式会社 | 液体混合機構及び液体混合方法 |
| US7718099B2 (en) * | 2002-04-25 | 2010-05-18 | Tosoh Corporation | Fine channel device, fine particle producing method and solvent extraction method |
| EP1391237B1 (en) * | 2002-08-01 | 2011-09-21 | Tosoh Corporation | Fine channel device, desksize chemical plant and fine particle producing apparatus employing them |
| EP1601874B1 (en) * | 2003-03-10 | 2009-05-27 | The Regents Of The University Of Michigan | Integrated microfluidic control employing programmable tactile actuators |
| JP4346456B2 (ja) | 2004-01-19 | 2009-10-21 | 株式会社Ｋｒｉ | 微粒子製造装置 |
| GB0418447D0 (en) | 2004-08-19 | 2004-09-22 | Advanced Phytonics Ltd | Process for preparing particles and apparatus |
| JP4822689B2 (ja) | 2004-10-29 | 2011-11-24 | 株式会社Ｋｒｉ | 微生物単離装置、微生物の単離方法および該方法で得られた微生物含有微粒子 |
| JP4713397B2 (ja) * | 2006-01-18 | 2011-06-29 | 株式会社リコー | 微小流路構造体及び微小液滴生成システム |
| WO2007150030A2 (en) | 2006-06-23 | 2007-12-27 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| EP2069733A4 (en) | 2006-10-02 | 2013-07-10 | Nanomaterials Tech Pte Ltd | PROCESS FOR PRODUCING MICROPARTICLES AND PRECIPITATION NANOPARTICLES |
| CN107028886A (zh) | 2009-11-04 | 2017-08-11 | 不列颠哥伦比亚大学 | 含有核酸的脂质粒子及相关的方法 |
| WO2012016184A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
-
2014
- 2014-10-16 JP JP2016523932A patent/JP6640079B2/ja active Active
- 2014-10-16 US US15/029,993 patent/US10159652B2/en active Active
- 2014-10-16 EP EP14853947.1A patent/EP3057693A4/en active Pending
- 2014-10-16 CN CN201480068147.2A patent/CN105813721B/zh active Active
- 2014-10-16 CA CA2927358A patent/CA2927358C/en active Active
- 2014-10-16 WO PCT/US2014/060961 patent/WO2015057998A1/en not_active Ceased
-
2018
- 2018-11-08 US US16/184,869 patent/US20190076372A1/en not_active Abandoned
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