JP2017176500A - Liquid injector - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a liquid injector capable of reducing an amount of liquid to waste by minimizing a dead space of a liquid passage.SOLUTION: A liquid injector 1 includes: an outer casing 2 that has a liquid storage space in the inside, and a nozzle part 25 extending in a central axis 12 direction, at a distal end, and having a hole 251 communicated with the liquid storage space; a cap member 30 provided at the distal end of the outer casing 2 and having a seal cap 3 provided rotationally about the central axis 12 and movably in the central axis 12 direction of the outer casing 2 for sealing the hole 251; a hub 6; a needle tube 7; and a mechanism moving the cap member 30 in the central axis 12 direction, with the rotational turning of the cap member 30. The seal cap 3 includes a hole 321 extending in the central axis 12 direction and communicated with the needle tube 7. When the cap member 30 is located at a first position, the hole 251 is sealed by the seal cap 3, and the hole 321 is sealed by a tip surface of the nozzle part 25.SELECTED DRAWING: Figure 12

Description

  The present invention relates to a liquid injection device.

  There is known a liquid injection device that can be applied to a prefilled syringe that contains a chemical solution or the like in advance (see, for example, Patent Document 1). The liquid injection device described in Patent Document 1 includes an outer cylinder having a liquid storage space therein, a nozzle portion that is formed to protrude from the distal end portion of the outer cylinder, and that has a flow path that communicates with the liquid storage space therein, and a nozzle An inner plug that opens and closes the flow path, a hub attached to the inner plug, and a needle tube supported by the hub.

  The tip of the flow path of the nozzle part is formed by two side holes that open to the side surface of the nozzle part. The inner plug has two lateral holes and two longitudinal grooves communicating with the lateral holes and the needle tube, and the first position seals the side hole and closes the flow path. And a second position for opening the flow path. Moreover, the liquid injection device has a protector that covers the needle tip of the needle tube in an unused state, and is configured such that when the protector is rotated, the inner plug is also rotated.

  In the liquid injection device in the unused state, the inner stopper is located at the first position. In this case, each side hole of the nozzle portion is sealed with the inner stopper. Then, when the protector is operated to rotate the inner plug and move the inner plug to the second position, the lateral hole of the inner plug and the side hole of the nozzle portion communicate with each other. The space communicates with the needle tube. Thereby, the liquid can be injected.

  However, in the liquid injection device described in Patent Document 1, two side holes are provided in the nozzle portion, and two side holes are provided in the inner plug. Since the bypass flow path that largely bypasses the central axis is formed, there is a problem that the dead space becomes large and the amount of the chemical solution that is wasted increases.

  In addition, since the nozzle portion is provided with two side holes, it is difficult to seal the side holes in an unused state, that is, to seal the liquid storage space, as compared with the case of one hole. .

International Publication No. 2013/038887

  An object of the present invention is to provide a liquid injection device that can reduce a dead space in a liquid flow path and reduce the amount of wasted liquid.

Such an object is achieved by the present inventions (1) to (16) below.
(1) an outer cylinder having a liquid storage space inside, and having a nozzle portion that extends in the central axis direction at the tip and is formed with a first hole communicating with the liquid storage space;
A distal end portion of the outer cylinder is provided with a seal cap that is rotatable about the central axis of the outer cylinder and is movable in the direction of the central axis of the outer cylinder and that seals the first hole. A cap member;
A needle hub attached to the seal cap;
A needle tube supported at the tip of the needle hub;
A mechanism for moving the cap member in the direction of the central axis as the cap member rotates;
The seal cap has a sealing portion that seals the first hole, and a second hole that penetrates the seal cap and communicates with the needle tube in the vicinity of the sealing portion.
The cap member can be moved from the first position to a second position located on the tip side of the first position by the mechanism as the outer cylinder rotates.
When the cap member is located at the first position, the first hole is sealed by the sealing portion, and the second hole is sealed by the tip surface of the nozzle portion. And
When the cap member is located at the second position, the gap is between the first hole and the sealing portion, and between the second hole and the tip surface of the nozzle portion. When the gaps are generated, the first hole and the second hole communicate with each other, and the liquid storage space and the needle tube communicate with each other via the first hole and the second hole. A liquid injection device characterized by comprising:

(2) The seal cap includes a bottomed cylindrical main body portion having a bottom portion at a tip portion,
The sealing part is the liquid injection device according to the above (1) provided at the bottom.

(3) The sealing portion is provided at a base end portion of the bottom portion, and has a protruding portion protruding in the base end direction.
The liquid according to (2), wherein when the cap member is located at the first position, the protrusion is inserted into the first hole and seals the first hole. Injection device.

  (4) The liquid injection device according to (3), wherein the protrusion is detached from the first hole when the cap member is located at the second position.

  (5) The liquid injection device according to (3) or (4), wherein the protrusion has a recess at a base end portion thereof.

  (6) The liquid injection device according to any one of (1) to (5), wherein the seal cap has a ridge on the inner side thereof that makes contact with the outer peripheral portion of the nozzle portion over one turn.

  (7) The liquid injection device according to (6), wherein the seal cap includes a convex portion that is inward of the seal cap and is in contact with the outer peripheral portion of the nozzle portion on a proximal end side with respect to the convex line.

  (8) The liquid injection device according to any one of (1) to (7), wherein the seal cap has a concave portion on a tip surface.

  (9) The liquid injection device according to any one of (1) to (8), wherein the mechanism is a cam mechanism.

  (10) The liquid injection device according to any one of (1) to (9), wherein the mechanism is provided in the cap member and the outer cylinder.

  (11) The cam mechanism includes a cam groove provided on one of the cap member and the outer cylinder, and a cam follower provided on the other and inserted into the cam groove. Liquid injection device.

  (12) The cap member sandwiches a part of the seal cap and a part of the outer cylinder from the central axis direction of the outer cylinder, and prevents the seal cap from being detached from the distal end portion of the outer cylinder. The liquid injection device according to any one of (1) to (11), wherein the liquid injection device has a lock cap.

  (13) The cap member includes a part of the needle hub, a part of the seal cap, and a part of the outer cylinder, and a part of the seal cap includes a part of the needle hub and the outer cylinder. The lock cap (1) is sandwiched from the center axis direction of the outer cylinder so as to be positioned between a part of the outer cylinder and the needle hub and the seal cap are prevented from being detached from the distal end portion of the outer cylinder. ) To (11).

  (14) The liquid injecting device according to (12) or (13), wherein a part of the mechanism is provided in the lock cap.

(15) The outer cylinder includes a cylindrical barrel and a plate-like portion provided on the outer periphery of the proximal end portion of the trunk.
Any one of the above (1) to (14), in which another member is disposed on the inner side of the outer periphery of the body part or at the same position as the outer periphery of the body part as viewed from the central axis direction of the outer cylinder. The liquid injection device as described.

  (16) The liquid injection device according to any one of (1) to (15), wherein the liquid injection device is a prefilled syringe.

  According to the present invention, the first hole and the second hole that constitute the flow path that allows the liquid storage space and the needle tube to communicate with each other extend in the direction of the central axis of the outer cylinder. The dead space can be reduced, thereby reducing the amount of wasted liquid.

It is a figure which applies the liquid injection device of this invention to a prefilled syringe, and shows the unused state (initial state). It is sectional drawing in the AA line of the liquid injection instrument shown in FIG. It is a perspective view which shows the hub of the liquid injection instrument shown in FIG. It is a perspective view which shows the lock cap of the liquid injection instrument shown in FIG. It is a perspective view which shows the lock cap of the liquid injection instrument shown in FIG. It is a perspective view which shows the seal cap of the liquid injection instrument shown in FIG. It is sectional drawing which shows the seal cap of the liquid injection instrument shown in FIG. It is sectional drawing which shows the outer cylinder of the liquid injection instrument shown in FIG. It is sectional drawing of the nozzle part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing in the BB line of the liquid injection instrument shown in FIG. It is sectional drawing in the CC line of the liquid injection instrument shown in FIG. It is sectional drawing of the nozzle part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing of the nozzle part vicinity of the liquid injection instrument shown in FIG.

  Hereinafter, the liquid injection device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

  FIG. 1 is a diagram showing an unused state (initial state) of the liquid injection device of the present invention applied to a prefilled syringe. FIG. 1A is a front view, and FIG. 1B is a side view. FIG. 2 is a cross-sectional view taken along line AA of the liquid injection device shown in FIG. FIG. 3 is a perspective view showing a hub of the liquid injection device shown in FIG. 1. 4 and 5 are perspective views showing a lock cap of the liquid injection device shown in FIG. 1, respectively. FIG. 6 is a perspective view showing a seal cap of the liquid injection device shown in FIG. 1. FIG. 7 is a cross-sectional view showing a seal cap of the liquid injection device shown in FIG. FIG. 8 is a cross-sectional view showing an outer cylinder of the liquid injection device shown in FIG. FIG. 9 is a cross-sectional view of the vicinity of the nozzle portion of the liquid injection device shown in FIG. 10 is a cross-sectional view taken along line BB of the liquid injection device shown in FIG. FIG. 11 is a cross-sectional view taken along line CC of the liquid injection device shown in FIG. 12 and 13 are cross-sectional views of the vicinity of the nozzle portion of the liquid injection device shown in FIG.

  Hereinafter, for convenience of explanation, the lower side in FIGS. 1 to 13 is referred to as a “base end” and the upper side is referred to as a “tip”. Moreover, the up-down direction in FIGS. 1-13 is the "center axial direction", "axial direction", and "longitudinal direction" of a liquid injection instrument and an outer cylinder.

  A liquid injection device 1 shown in FIG. 1 and FIG. 2 is a medical device used when injecting a liquid into a living body. In this embodiment, the liquid injection device 1 is a prefilled syringe filled with a liquid such as a chemical solution in advance. Examples of the liquid include protein medical products such as antibodies, peptide medical products such as hormones, nucleic acid medical products, cell medicines, blood products, vaccines for preventing various infectious diseases, anticancer agents, anesthetics, medical treatments, etc. Narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, sugar injections such as heparin and glucose, electrolyte correction injections such as sodium chloride and potassium lactate, vitamins, fat emulsions, contrast agents, stimulants, etc. Is mentioned.

  As shown in FIG. 1 and FIG. 2, the liquid injection device 1 is installed in an outer cylinder (syringe outer cylinder) 2 that can be filled with a liquid, and the outer cylinder 2, along the direction of the central axis 12 of the outer cylinder 2. A slidable gasket 8, a plunger (operation member) 9 for moving the gasket 8 along the direction of the central axis 12 of the outer cylinder 2, that is, a pressing operation, a cap formed by the seal cap 3 and the lock cap 4. An injection needle 5 composed of a member 30, a needle tube 7 and a hub (needle hub) 6, and a protector 11 covering the needle tube 7 are provided. The gasket 8 is connected to the tip of the plunger 9.

  As shown in FIG. 8, the outer cylinder 2 is comprised with the bottomed cylindrical member. That is, the outer cylinder 2 includes a bottom portion 21 provided at the distal end portion, and a cylindrical trunk portion 22 formed of a side wall standing from the edge portion of the bottom portion 21 toward the proximal end direction. 22 has an opening at the base end. The bottom 21 has a mortar shape. A liquid storage space 24 is formed in the outer cylinder 2, that is, in a portion surrounded by the outer cylinder 2 and the gasket 8. The liquid storage space 24 can be filled with a liquid. In the present embodiment, the liquid is stored in advance.

  Moreover, although the scale (not shown) which shows the liquid quantity is attached | subjected to the outer peripheral surface of the outer cylinder 2, the said scale may be abbreviate | omitted.

  Moreover, it is preferable that the outer cylinder 2 is substantially transparent in order to ensure internal visibility. Thereby, the liquid can be visually recognized.

  Further, a flange 23 is integrally formed as a plate-like portion on the outer periphery of the base end portion of the outer cylinder 2, that is, on the outer periphery of the base end portion of the body portion 22. When the plunger 9 is moved relative to the outer cylinder 2, the operation can be performed by putting a finger on the flange 23.

  In addition, a nozzle portion 25 that is reduced in diameter with respect to the body portion 22 of the outer cylinder 2 and protrudes toward the distal end is integrally formed at the center portion of the bottom portion 21 at the distal end portion of the outer cylinder 2.

  The nozzle portion 25 has a cylindrical shape. Further, the nozzle portion 25 is formed with a hole (first hole) 251 that is arranged coaxially with the central axis 12 and extends in the direction of the central axis 12. The hole 251 is formed from the proximal end to the distal end of the nozzle portion 25, opens to the distal end and the proximal end of the nozzle portion 25, and communicates with the liquid storage space 24. The lumen of the hole 251 forms a flow path through which the liquid passes, communicates with the liquid storage space 24, and opens at the tip of the nozzle portion 25.

  A cam follower 26 is integrally formed at a portion between the distal end portion of the bottom portion 21 of the outer cylinder 2 and the proximal end portion of the nozzle portion 25. The cam follower 26 is configured by a protrusion that protrudes in a direction orthogonal to the central axis 12, that is, in the radial direction of the outer cylinder 2.

  Further, the number of cam followers 26 is not particularly limited, and may be one or plural, but preferably plural. In the present embodiment, the number of cam followers 26 is set to four, and the cam followers 26 are arranged at equal intervals, that is, at 90 ° intervals at the central angle when viewed from the direction of the central axis 12.

  Further, other members to be described later, that is, a cap member 30 composed of a seal cap 3 and a lock cap 4, an injection needle 5 composed of a needle tube 7 and a hub 6, a gasket 8, a plunger 9, and a protector 11 Is arranged on the inner side of the outer periphery of the body portion 22 of the outer cylinder or at the same position as the outer periphery of the body portion 22 when viewed from the direction of the central axis 12.

  As shown in FIGS. 6 and 7, the seal cap 3 of the cap member 30 has a bottomed cylindrical main body 31 having a bottom 32 at the tip. As will be described later, the constituent material of the seal cap 3 is not particularly limited, but in the present embodiment, a case where the seal cap 3 is made of an elastic material will be described as an example.

  As shown in FIG. 9, the seal cap 3, that is, the cap member 30 is rotatable around the central axis 12 at the tip of the outer cylinder 2, that is, the nozzle portion 25, and moves in the direction of the central axis 12. It is installed as possible.

  The seal cap 3 has a function of sealing the hole 251 of the outer cylinder 2. From the first position where the hole 251 is sealed by the seal cap 3 (see FIG. 12), the first position Is also located on the distal end side, and is configured to be located at a second position (see FIG. 13) in which a hole 251 and a hole 321 described later of the seal cap 3 communicate with each other. In the unused state of the liquid injection device 1, that is, in the initial state, the seal cap 3, that is, the cap member 30, is located at the first position.

  A hole (second hole) 321 through which a liquid passes is formed inside the bottom 32 of the seal cap 3. The number of the holes 321 is not particularly limited, and may be one or plural, but preferably plural. Of the plurality, the smaller one is preferable. Thereby, the dead space can be reduced in the liquid flow path, and the amount of wasted liquid can be reduced. In the present embodiment, the number of holes 321 is set to two, and each hole 321 is arranged at a position facing the center axis 12 when viewed from the direction of the center axis 12.

  Further, each hole 321 is arranged at a position shifted from the central axis 12 and extends in the direction of the central axis 12. Each hole 321 is open to the distal end and the proximal end of the bottom portion 32, respectively, and communicates with the needle tube 7 of the injection needle 5 through a flow path 62 described later shown in FIG. Moreover, each hole 321 is arrange | positioned in the vicinity of the protrusion part 323 which is an example of the sealing part mentioned later, respectively. Thereby, the volume of the flow path until the liquid discharged | emitted from the front-end | tip of the nozzle part 25 reaches the hole 321 becomes small, and a dead space can be made small.

  In addition, a concave portion 322 that is open to the tip of the bottom 32 is formed on the tip of the bottom 32. Thereby, for example, even when the bottom portion 32 is deformed and the flow path 62 is closed, the hole 321 and the needle tube 7 can be communicated with each other through the concave portion 322.

  The shape of the concave portion 322 is not particularly limited, but in the present embodiment, the concave portion 322 has a circular shape in plan view, that is, when viewed from the direction of the central axis 12.

  The seal cap 3 has a protruding portion 323 that is formed at the base end portion of the bottom portion 32 and protrudes in the base end direction as a sealing portion that seals the hole 251. The protruding portion 323 has a columnar shape and is arranged coaxially with the central axis 12.

  Moreover, the protrusion part 323 has the recessed part 324 open | released at the base end in the base end part. By the recess 324, a ring-shaped rib 325 that protrudes in the proximal direction is formed on the outer peripheral portion of the proximal end portion of the protruding portion 323.

  In addition, a ring-shaped rib (protrusion) 311 along the circumferential direction is formed on the inner peripheral portion at the distal end portion of the main body portion 31 and on the proximal end side with respect to the bottom portion 32. The rib 311 protrudes in the radial direction of the main body 31. The rib 311 is formed on the inner peripheral portion of the main body 31 over the entire circumference, and is in contact with the outer peripheral portion of the tip portion of the nozzle portion 25 over the entire circumference. Thereby, the liquid leak from the front-end | tip part of the nozzle part 25 can be prevented more reliably.

  Further, a ring-shaped rib 312 along the circumferential direction is provided on the inner peripheral portion of the main body 31 and on the base end side of the rib 311, that is, on the inner peripheral portion of the base end portion of the main body 31. Is formed. In addition, the rib 312 protrudes in the radial direction of the main body 31. The rib 312 is formed on the inner peripheral portion of the main body 31 over the entire circumference, and is in contact with the outer peripheral portion of the proximal end portion of the nozzle portion 25 over the entire circumference. As a result, the seal cap 3 is supported by the nozzle portion 25 at two locations of the rib 311 and the rib 312, thereby preventing the seal cap 3 from wobbling.

  The rib 312 is an example of a convex portion. In the present embodiment, the rib 312 is formed over the inner peripheral portion of the main body portion 31 over the entire circumference. However, the rib 312 is not limited thereto, and is, for example, C-shaped, that is, 1 It may be formed in a range less than the circumference, or may be composed of a plurality of protrusions arranged at a predetermined interval.

  A flange 33 is integrally formed on the outer periphery of the base end portion of the seal cap 3.

  As shown in FIG. 12, when the cap member 30 is located at the first position, the hole 251 of the outer cylinder 2 and the hole 321 of the seal cap 3 do not communicate with each other, and the hole 251 Sealed by the bottom portion 32, each hole 321 is sealed by the front end surface of the nozzle portion 25 of the outer cylinder 2. In this case, the protruding portion 323 of the bottom portion 32 is inserted into the hole 251 and seals the hole 251. Moreover, since the recessed part 324 is provided in the protrusion part 323, when a pressure is applied to the recessed part 324, the rib 325 spreads to an outer peripheral side, and the rib 325 and the front-end | tip part of the nozzle part 25 adhere more closely. Thereby, the hole 251 can be sealed more reliably and liquid leakage can be prevented.

  When the seal cap 3, that is, the cap member 30, is rotated in a predetermined direction, the cam followers 26 are relatively moved along cam grooves 423 (described later) shown in FIG. 2 in the tip direction. When the cap member 30 rotates by a predetermined angle in the predetermined direction from the first position, the cap member 30 moves to the second position shown in FIG. The second position is a position closer to the tip than the first position.

  As shown in FIG. 13, when the cap member 30 is located at the second position, the hole 251 and the hole 321 communicate with each other, and the liquid storage space 24 and the needle tube 7 are connected via the hole 251 and the hole 321. And communicate with each other. In this case, the protruding portion 323 is detached from the hole 251, and is between the tip surface of the nozzle portion 25 and the bottom portion 32, that is, between the hole 251 and the protruding portion 323, and between the hole 321 and the tip surface of the nozzle portion 25. A gap is generated between the hole 251 and the hole 321 through the gap.

  As shown in FIG. 9, the lock cap 4 of the cap member 30 is attached to the outer periphery of the outer cylinder 2 and the hub 6. In this embodiment, the lock cap 4 is installed integrally with the seal cap 3 so as to be rotatable around the central axis 12 and movable in the direction of the central axis 12. The lock cap 4 sandwiches a part of the hub 6, a part of the seal cap 3, and a part of the outer cylinder 2 from the direction of the central axis 12, and the hub 6 and the seal cap 3 from the tip of the outer cylinder 2. Has the function of preventing the detachment.

  As shown in FIGS. 4 and 5, the lock cap 4 includes a pair of first clamping portions 41 disposed at positions facing each other via the central axis 12 when viewed from the direction of the central axis 12, and each first clamping pin. It has the 2nd clamping part 42 arrange | positioned rather than the part 41 at the base end side, and the four connection parts 43 which connect each 1st clamping part 41 and the 2nd clamping part 42. FIG. Each of the first clamping parts 41 and the second clamping part 42 are connected by connecting parts 43 at both ends of the first clamping part 41.

  Each first sandwiching portion 41 has an arc shape. Moreover, the 2nd clamping part 42 has the plate-shaped part 421 which makes a disk shape, and protrudes in the base end direction from the outer peripheral part of the plate-shaped part 421, and has the cylindrical part 422 which makes | forms a cylinder shape. Moreover, each connection part 43 has the plane part 431 inside, respectively.

  A part of the flange 33 of the seal cap 3 is inserted into a hole 44 formed on the proximal end side of each first clamping part 41.

  Similarly, a part of a flange 61 of the hub 6 described later is inserted into a hole 44 formed on the proximal end side of each first clamping portion 41.

  Further, a cam groove 423 is formed in the inner peripheral portion of the cylindrical portion 422 of the second clamping portion 42, and the cam follower 26 of the outer cylinder 2 is inserted into the cam groove 423 as shown in FIG. Has been. The cam groove 423 has a spiral shape, and in this embodiment, the cam groove 423 is formed in a range of less than one round of the inner circumferential portion of the cylindrical portion 422.

  Further, the number of cam grooves 423 is not particularly limited, and may be one or plural, but preferably plural. In the present embodiment, the number of cam grooves 423 is set to four, and the cam grooves 423 are arranged at equal intervals, that is, at 90 ° intervals at the central angle when viewed from the direction of the central axis 12. .

  The cam groove 423 is a bottomed groove in the present embodiment, but is not limited thereto, and may be, for example, a bottomless groove, that is, a through hole.

  A mechanism for moving the lock cap 4 in the direction of the central axis 12 with the rotation of the lock cap 4 by the respective cam grooves 423 and the respective cam followers 26 of the outer cylinder 2, that is, the cap with the rotation of the cap member 30. A cam mechanism which is an example of a mechanism for moving the member 30 in the direction of the central axis 12 is configured.

  In the present embodiment, the cam follower 26 is provided in the outer cylinder 2 and the cam groove 423 is provided in the lock cap 4. However, the present invention is not limited to this. For example, the cam groove is provided in the outer cylinder 2 and the lock cap is provided. 4 may be provided with a cam follower.

  From another point of view, as shown in FIG. 9, the cam grooves 423 of the second clamping portion 42 of the lock cap 4 and the cam followers 26 of the outer cylinder 2 are engaged in the direction of the central axis 12. doing. In this case, the base end side surface of the cam groove 423 is engaged with the base end side of the cam follower 26. Further, the first clamping portion 41 of the lock cap 4 and a flange 61 of the hub 6 described later are engaged in the direction of the central axis 12. In this case, the first clamping part 41 is engaged with the distal end side of the flange 61. Further, the flange 33 of the seal cap 3 is disposed between the flange 61 of the hub 6 and the plate-like portion 421 of the second clamping portion 42 and engages with the flange 61 and the plate-like portion 421 in the direction of the central axis 12. ing.

  Thus, the flange 61 of the hub 6, the flange 33 of the seal cap 3, and the cam followers 26 of the outer cylinder 2 are arranged in this order from the distal end side to the proximal end side. It is sandwiched from the direction of the central axis 12.

  Thereby, the hub 6 and the seal cap 3 are prevented from being detached from the distal end portion of the outer cylinder 2. In particular, the seal cap 3 made of an elastic material has the flange 33 sandwiched between the flange 61 of the hub 6 and the plate-like portion 421 of the second sandwiching portion 42, so that the seal cap starts from the distal end portion of the outer cylinder 2. It is possible to prevent the separation of 3 more reliably.

  Further, as will be described later, the base end portion of the protector 11 is in contact with the first clamping portion 41 of the lock cap 4, whereby the protector 11, the hub 6, the lock cap 4, and the seal cap 3 Are integrally movable in the direction of the central axis 12, that is, in the direction of the tip along the central axis.

As shown in FIG. 2, the injection needle 5 is attached to the outer peripheral portion of the main body 31 of the seal cap 3. In this embodiment, the injection needle 5 is installed integrally with the cap member 30 so as to be rotatable around the central axis 12 and movable in the direction of the central axis 12.
The injection needle 5 has a hub 6 and a needle tube 7 that is supported and fixed to the tip of the hub 6.

  The hub 6 is composed of a cylindrical member, and the seal cap 3 is inserted into the proximal end portion of the inner cavity portion thereof. As a result, the hub 6 is attached to the main body 31 of the seal cap 3. At this time, the inner surface of the hub 6 and the outer surface of the bottom 32 of the main body 31 can be brought into close contact with each other, and the liquid tightness of the flow path through which the liquid flows can be maintained.

  Also, as shown in FIG. 12, a flow path 62 that connects the hole 321 and the needle tube 7 is formed between the inner surface of the hub 6 and the tip surface of the bottom portion 32.

  Further, as shown in FIG. 3, a flange 61 is integrally formed on the outer periphery of the base end portion of the hub 6. The flange 61 is in contact with the flange 33 of the seal cap 3.

  A hollow needle tube 7 is inserted at the distal end of the inner cavity of the hub 6. The needle tube 7 is fixed to the hub 6 in a liquid-tight manner by, for example, a method using an adhesive or a solvent. The needle tube 7 thus fixed has a lumen communicating with the lumen of the hub 6.

  A sharp needle tip is formed at the tip of the needle tube 7. Thereby, the target site can be punctured and the liquid can be injected in that state. The shape of the needle tip is not particularly limited, and preferably has a shape having a blade surface inclined at a predetermined angle with respect to the central axis 12, that is, the axis of the needle tube 7, as shown in FIG.

  As shown in FIGS. 1, 2, and 9, a protector 11 is attached to the hub 6. In this embodiment, the protector 11 is installed integrally with the cap member 30 so as to be rotatable around the central axis 12 and movable in the direction of the central axis 12. In addition, the injection needle 5 is arranged inside the protector 11 in the mounted state, and the protector 11 can cover the distal end side of the outer cylinder 2, that is, at least the needle tube 7 of the injection needle 5.

  The protector 11 has a bottomed cylindrical shape having a bottom at the tip. That is, the tip of the protector 11 is closed. Therefore, the protector 11 also has a function of keeping the sterility of the needle tube 7, that is, a function of blocking bacteria from entering between the needle tube 7 and the protector 11. As shown in FIG. 9, the proximal end portion of the protector 11 is in contact with the first clamping portion 41 of the lock cap 4.

  The constituent materials of the outer cylinder 2, the lock cap 4, the hub 6, the plunger 9, and the protector 11 are not particularly limited. For example, a cyclic olefin polymer (for example, ethylene and tetracyclo [4.4.0.12. 5.17.10] -3-dodecene copolymer or hydrogenated cycloolefin polymer), polyvinyl chloride, polyethylene, polypropylene, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylic Nitrile-butadiene-styrene copolymer, polyester such as polyethylene terephthalate, butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12), polyethersulfone, polysulfone, etc. Various resins It is below. Among them, a cyclic olefin polymer (for example, ethylene and tetracyclo [4.4.0.12.5.17.10] -3-dodecene copolymer, hydrogen-based cycloolefin polymer, etc.) in that molding is easy. ), Polypropylene, poly- (4-methylpentene-1), polyethersulfone, and polysulfone are preferred.

  The constituent material of the needle tube 7 is not particularly limited, and examples thereof include a metal material such as stainless steel, aluminum or aluminum alloy, titanium or titanium alloy, and the like.

  The elastic material constituting the gasket 8 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, polyurethane, polyester Examples thereof include elastic materials such as various thermoplastic elastomers such as polyamides, polyamides, olefins, and styrenes, or mixtures thereof.

  Further, the constituent material of the seal cap 3 is not particularly limited. For example, in addition to the resins mentioned as the constituent material of the outer cylinder 2, resins such as HDPE (high density polyethylene) and LDPE (low density polyethylene), The elastic material mentioned as a constituent material of the said gasket 8 is mentioned, Among these, an elastic material is preferable. In the illustrated configuration, the seal cap 3 is made of an elastic material. In addition, only the part which contact | connects the seal cap 3 with a liquid may be comprised with an elastic material, and the other part may be comprised with resin.

  In the liquid injection device 1, the protector 11, the hub 6, and the cap member 30 can be integrally rotated around the central axis 12 with respect to the outer cylinder 2 and in the direction of the central axis 12. It is configured to be movable. Since the structure for moving the protector 11, the hub 6, the lock cap 4 and the seal cap 3 integrally in the direction of the central axis 12 has already been described, hereinafter, the structure for integrally rotating around the central axis 12 will be described. The configuration will be described.

  First, as shown in FIG. 11, four protrusions 111 are formed at equiangular intervals, that is, 90 ° intervals on the inner peripheral portion of the protector 11. Further, four protrusions 63 are formed at equiangular intervals, that is, 90 ° intervals on the inner peripheral portion of the hub 6. The protrusions 111 of the protector 11 and the protrusions 63 of the hub 6 are engaged in the circumferential direction of the outer cylinder 2.

  Thereby, when the protector 11 rotates counterclockwise in FIG. 11, the hub 6 also rotates. Therefore, each protrusion 111 of the protector 11 constitutes a sixth engaging part, and each protrusion 63 of the hub 6 constitutes a fifth engaging part.

  As shown in FIGS. 9 and 10, the flange 61 of the hub 6 and the connecting portion 43 of the lock cap 4 are engaged in the circumferential direction of the outer cylinder 2.

  Thereby, when the hub 6 rotates, the lock cap 4 also rotates. Accordingly, the portion of the flange 61 of the hub 6 that contacts the connecting portion 43 constitutes the fourth engaging portion, and the portion of the connecting portion 43 of the lock cap 4 that contacts the flange 61 is the third engaging portion. The engaging portion is configured.

  As shown in FIG. 9, the connecting portion 43 of the lock cap 4 and the flange 33 of the seal cap 3 are engaged in the circumferential direction of the outer cylinder 2.

  Thereby, when the lock cap 4 rotates, the seal cap 3 also rotates. Therefore, the portion of the connecting portion 43 of the lock cap 4 that contacts the flange 33 constitutes the second engaging portion, and the portion of the flange 33 of the seal cap 3 that contacts the connecting portion 43 is the first engaging portion. The engaging portion is configured.

  With such a configuration, when the protector 11 is rotated in a predetermined direction around the central axis 12, the protector 11, the hub 6, the lock cap 4, and the seal cap 3 are integrally rotated.

Next, an operation method of the liquid injection device 1 will be described.
[1] First, an unused liquid injection device 1 shown in FIGS. 1 and 2 is prepared. As shown in FIG. 12, in the liquid injection device 1, the cap member 30 is located at the first position, whereby the hole 251 of the nozzle portion 25 and the hole 321 of the seal cap 3 are closed. That is, the hole 251 of the nozzle portion 25 and the hole 321 of the seal cap 3 are blocked.

  [2] Next, the protector 11 is held with one hand, and the outer cylinder 2 is held with the other hand. Then, as it is, the protector 11 is rotated in a predetermined direction around the central axis 12 to rotate the protector 11. Thereby, the protector 11, the hub 6, the lock cap 4 and the seal cap 3 are integrally rotated with respect to the outer cylinder 2. Further, the rotation of the lock cap 4 with respect to the outer cylinder 2 causes the cam followers 26 of the outer cylinder 2 to move relative to each other along the cam grooves 423 of the lock cap 4, whereby the protector 11, the hub 6, the lock The cap 4 and the seal cap 3 are integrally moved with respect to the outer cylinder 2 in the distal direction.

  When the protector 11 rotates by a predetermined angle, that is, a predetermined angle of less than 90 ° in this embodiment, the cap member 30 is positioned at the second position as shown in FIG. Thereby, the hole 251 of the nozzle part 25 and the hole 321 of the seal cap 3 communicate, and the hole 251 becomes an open state. That is, the liquid storage space 24 and the needle tube 7 communicate with each other through the holes 251 and 321 and the like.

  [3] Next, the protector 11 is removed. Thereby, the needle tip of the injection needle 5 is exposed. Thereafter, the needle tip of the injection needle 5 is punctured into the target site, and the plunger 9 is pressed while in the punctured state. Thereby, the liquid can be injected.

  As described above, according to the liquid injection device 1, since the holes 251 and 321 constituting the flow path for communicating the liquid storage space 24 and the needle tube 7 each extend in the direction of the central axis 12, The dead space can be reduced with respect to the flow path, thereby reducing the amount of wasted liquid.

  In the liquid injection device 1, the protector 11 protects the needle tip of the needle tube 7 of the injection needle 5 and is not a rubber stopper. Thereby, the puncture resistance and coring which are generated when the rubber stopper is punctured with the needle tip of the injection needle 5 can be prevented, and the liquid injection device 1 can be easily manufactured. In addition, when the needle tube 7 is 31G or thinner, if the needle tip of the needle tube 7 is to be protected with a rubber plug, problems such as the needle tube 7 being bent or the needle tip being crushed when puncturing the rubber plug occur. There is a fear. Such a problem can be prevented in the liquid injection device 1.

  Further, since the hole that communicates with the liquid storage space 24 and opens to the outside in the nozzle portion 25 is a single hole 251, the hole 251 can be easily and reliably sealed in an unused state. The liquid storage space 24 can be easily and reliably sealed.

  Further, by rotating the protector 11 by a small angle of less than 90 °, the liquid storage space 24 can be brought into communication with the needle tube 7 from the sealed state of the liquid storage space 24, so that the operation is easy. And can be operated quickly.

  As mentioned above, although the liquid injection device of the present invention has been described based on the illustrated embodiment, the present invention is not limited to this, and each part is replaced with an arbitrary configuration that can exhibit the same function. can do. Moreover, arbitrary components may be added.

  In the above embodiment, the seal cap can be rotated around the central axis of the outer cylinder and can be moved in the direction of the central axis of the outer cylinder. The cap does not need to rotate, and may be movable in the central axis direction.

  In the present invention, the seal cap and the lock cap may be integrally formed.

  Moreover, in this invention, a cam mechanism is not limited to the structure of the said embodiment, Various cam mechanisms can be applied. As an example, for example, one member of the cap member and the outer cylinder is provided with a spiral surface disposed along the circumferential direction and inclined toward the distal direction, and the base end portion of the other member is provided. Abut on the surface. Alternatively, the other member is provided with an engaging portion such as a protrusion that engages with the surface.

  Moreover, in the said embodiment, although the cam mechanism is provided in the lock cap and the outer cylinder, in this invention, it is not restricted to this, For example, the cam mechanism is provided in the seal cap and the outer cylinder. In addition, the seal cap, the lock cap, and the outer cylinder may be provided.

  In the present invention, the mechanism that converts the rotation of the cap member into the movement of the cap member toward the central axis of the outer cylinder may be a mechanism other than the cam mechanism.

  In the above embodiment, the outer cylinder is preliminarily filled with the liquid. However, the present invention is not limited to this. For example, the outer cylinder is not initially filled with the liquid, and the outer cylinder is filled later. The liquid may be filled and used.

  In the present invention, the gasket may be omitted. In this case, for example, the distal end portion of the plunger is configured to function as a gasket.

DESCRIPTION OF SYMBOLS 1 ... Liquid injection device 2 ... Outer cylinder 3 ... Seal cap 4 ... Lock cap 5 ... Injection needle 6 ... Hub 7 ... Needle tube 8 ... Gasket 9 ... Plunger 11 ... Protector 12 ... Center shaft 21 ... Bottom 22 ... Trunk 23 ... Flange 24 ... Liquid storage space 25 ... Nozzle part 26 ... Cam follower 30 ... Cap member 31 ... Main body part 32 ... Bottom part 33 ... Flange 41 ... First clamping part 42 ... Second clamping part 43 ... Connecting part 44 ... Hole 61 ... Flange 62 ... Flow path 63... Projection 111. Projection 251.

Claims (16)

An outer cylinder having a liquid storage space therein, and having a nozzle portion extending in the central axis direction at the tip and having a first hole communicating with the liquid storage space;
A distal end portion of the outer cylinder is provided with a seal cap that is rotatable about the central axis of the outer cylinder and is movable in the direction of the central axis of the outer cylinder and that seals the first hole. A cap member;
A needle hub attached to the seal cap;
A needle tube supported at the tip of the needle hub;
A mechanism for moving the cap member in the direction of the central axis as the cap member rotates;
The seal cap has a sealing portion that seals the first hole, and a second hole that penetrates the seal cap and communicates with the needle tube in the vicinity of the sealing portion.
The cap member can be moved from the first position to a second position located on the tip side of the first position by the mechanism as the outer cylinder rotates.
When the cap member is located at the first position, the first hole is sealed by the sealing portion, and the second hole is sealed by the tip surface of the nozzle portion. And
When the cap member is located at the second position, the gap is between the first hole and the sealing portion, and between the second hole and the tip surface of the nozzle portion. When the gaps are generated, the first hole and the second hole communicate with each other, and the liquid storage space and the needle tube communicate with each other via the first hole and the second hole. A liquid injection device characterized by comprising: The seal cap includes a bottomed cylindrical main body having a bottom at the tip,
The liquid injection device according to claim 1, wherein the sealing portion is provided on the bottom portion. The sealing portion is provided at the base end portion of the bottom portion, and has a protruding portion protruding in the base end direction,
3. The liquid injection according to claim 2, wherein when the cap member is located at the first position, the protrusion is inserted into the first hole and seals the first hole. Instruments.   4. The liquid injection device according to claim 3, wherein when the cap member is located at the second position, the protrusion is detached from the first hole.   The liquid injecting device according to claim 3 or 4, wherein the protrusion has a recess at a base end thereof.   The liquid injection device according to any one of claims 1 to 5, wherein the seal cap has a protrusion on the inner side thereof that makes contact with the outer peripheral portion of the nozzle portion over one turn.   The liquid injection device according to claim 6, wherein the seal cap has a convex part that is in contact with the outer peripheral part of the nozzle part on the inner side of the seal cap and closer to the base end side than the convex line.   The liquid injection device according to any one of claims 1 to 7, wherein the seal cap has a concave portion at a distal end surface.   The liquid injection device according to any one of claims 1 to 8, wherein the mechanism is a cam mechanism.   The liquid injection device according to claim 1, wherein the mechanism is provided on the cap member and the outer cylinder.   The liquid injection device according to claim 9, wherein the cam mechanism includes a cam groove provided in one of the cap member and the outer cylinder, and a cam follower provided in the other and inserted into the cam groove. .   The cap member is a lock cap that sandwiches a part of the seal cap and a part of the outer cylinder from the central axis direction of the outer cylinder, and prevents the seal cap from being detached from the distal end portion of the outer cylinder. The liquid injection device according to claim 1, comprising:   The cap member includes a part of the needle hub, a part of the seal cap, and a part of the outer cylinder. A part of the seal cap is a part of the needle hub and a part of the outer cylinder. 12. A lock cap that is sandwiched between the outer cylinder and the center of the outer cylinder so that the needle hub and the seal cap are prevented from being detached from a distal end portion of the outer cylinder so as to be positioned between The liquid injection device according to any one of the above.   The liquid injection device according to claim 12 or 13, wherein a part of the mechanism is provided on the lock cap. The outer cylinder has a cylindrical body part and a plate-like part provided on the outer periphery of the base end part of the body part,
The other member is arrange | positioned in the same position as the outer periphery of the said trunk | drum inside or the outer periphery of the said trunk | drum seeing from the central-axis direction of the said outer cylinder. Liquid injection device.   The liquid injection device according to any one of claims 1 to 15, wherein the liquid injection device is a prefilled syringe.

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