WO2012043194A1

WO2012043194A1 - Syringe

Info

Publication number: WO2012043194A1
Application number: PCT/JP2011/070624
Authority: WO
Inventors: 小川　淳一; 立川　浩一
Original assignee: テルモ株式会社
Priority date: 2010-09-29
Filing date: 2011-09-09
Publication date: 2012-04-05

Abstract

Provided is a syringe which includes an elongated syringe body, the syringe body having a first space and a second space which are disposed therein side by side in a direction orthogonal to the longitudinal direction and which are separated from each other; a nozzle disposed on a tip end side of the syringe body to communicate with the syringe body; a first gasket inserted into the first space to be slidable in the longitudinal direction of the syringe body; a second gasket inserted into the second space to be slidable in the longitudinal direction of the syringe body; a medicine stored in a portion closer to the tip end than to the first gasket in the first space; a liquid stored in a portion closer to the tip end than to the second gasket in the second space; and a switching means for switching among the communication patterns of the first space, the second space, and the nozzle.

Description

Syringe

The present invention relates to a syringe.

A two-chamber prefilled syringe in which a powder medicine and a liquid for dissolving the medicine are separated from each other and sealed in two chambers is known. As this two-chamber type prefilled syringe, an outer cylinder, a first gasket that can slide in the outer cylinder, and a slide that can slide in the outer cylinder, are arranged on the proximal end side than the first gasket. A second gasket and a plunger for moving and operating the second gasket, wherein powder is stored in a first space surrounded by the outer cylinder and the first gasket, and the outer cylinder and the second gasket; There is one in which a liquid is stored in a second space surrounded by (see, for example, Patent Document 1).

In the two-chamber prefilled syringe described in Patent Document 1, since the first space and the second space are disposed along the longitudinal direction of the outer cylinder, the entire length is increased accordingly. For this reason, when trying to use this two-chamber prefilled syringe, depending on the size of the hand of the operator who operates the syringe, one hand holds from the outer cylinder to the plunger, that is, the index finger is attached to the flange of the outer cylinder. In some cases, it is difficult to hang the thumb on the flange of the plunger.

JP-A-60-72561

An object of the present invention is to provide a two-chamber syringe that is advantageous for downsizing.

In order to achieve the above object, the present invention provides:
A syringe body having a long shape, the syringe body having a first space and a second space that are arranged side by side along the direction orthogonal to the longitudinal direction and partitioned from each other,
A nozzle disposed on the distal end side of the syringe body and communicating with the inside of the syringe body;
A first gasket inserted into the first space and slidable along the longitudinal direction of the syringe body;
A second gasket inserted into the second space and slidable along the longitudinal direction of the syringe body;
A medicine housed in a portion on the tip side of the first gasket in the first space;
A liquid stored in a portion of the second space on the tip side of the second gasket;
Switching means for switching a communication pattern between the first space, the second space, and the nozzle;
The switching means includes a first state in which the first space, the second space, and the nozzle are blocked from each other, and the first space and the second space communicate with each other. The second state that is blocked from the first space and the second space, one of the first space and the second space, and the nozzle communicate with each other, and the other space. Is a syringe that is configured to switch to a third state that is blocked from the one space and the nozzle.

Further, in the syringe of the present invention, the switching means is composed of a plate member arranged in parallel with a direction orthogonal to the longitudinal direction of the syringe body between the syringe body and the nozzle, and is formed on a base end surface thereof. A valve body having a groove formed, a through hole formed through the plate member in the thickness direction, and a rotation operation unit that rotates the valve body about its central axis,
By operating the rotation operation unit, the positional relationship between the groove and the through hole, the first space, and the second space is changed, and in the first state, the base of the valve body is changed. The first space and the second space are sealed at the end face, and in the second state, the first space and the second space communicate with each other through the groove, and the third space In this state, it is preferable that the one space and the nozzle communicate with each other through the through hole, and the other space is sealed at the base end face of the valve body.

Further, in the syringe of the present invention, it is preferable that an airtightness maintaining means for maintaining airtightness between the syringe main body and the valve body is provided when the rotary operation unit is operated.

Further, in the syringe of the present invention, the airtightness maintaining means includes a protrusion formed in a ring shape around the central axis on one surface of the distal end surface of the syringe body and the proximal end surface of the valve body. Preferably, the other surface is formed in a ring shape around the central axis, and the groove is inserted in close contact with the protrusion.

In the syringe of the present invention, in the second state, the first gasket moves in the proximal direction to reduce the pressure in the first space, or the second gasket When the pressure in the second space is increased by moving in the distal direction, the liquid in the second space flows into the first space and is mixed with the drug to generate a drug solution. Is preferred.

In the syringe of the present invention, the syringe body is formed by connecting or integrally forming two cylinders, and an inner space of one of the two cylinders is the first cylinder. It is preferable that the inner space of the other cylindrical body functions as the second space.

The syringe of the present invention preferably further includes a plunger connected to one of the first gasket and the second gasket and moving the connected gasket.

Further, in the syringe of the present invention, the nozzle is configured such that the hub of a puncture needle having a hollow needle having a sharp needle tip at a distal end and a hub fixed to a proximal end portion of the hollow needle can be mounted. It is preferable.

Further, in the syringe of the present invention, it is preferably in the first state when not in use, and the first gasket is preferably located on the tip side of the second gasket.

In the syringe of the present invention, it is preferable that the chemical solution in the first space is discharged from the nozzle by moving the first gasket in the distal direction in the third state.

In the syringe of the present invention, it is preferable that the shape and size of the cross section of each cylindrical body are the same.

Moreover, in the syringe of the present invention, it is preferable that the syringe main body has a flat shape as a whole.

In the syringe of the present invention, it is preferable that the drug is in a powder form.
In the syringe of the present invention, it is preferable that the liquid dissolves the drug.

FIG. 1 is a partial vertical cross-sectional view sequentially illustrating the operation process of the syringe (first embodiment) of the present invention. FIG. 2 is a partial vertical cross-sectional view sequentially illustrating the operation process of the syringe (first embodiment) of the present invention. FIG. 3 is a partial vertical cross-sectional view sequentially illustrating the operation process of the syringe (first embodiment) of the present invention. FIG. 4 is a partial vertical cross-sectional view sequentially illustrating the operation process of the syringe (first embodiment) of the present invention. FIG. 5 is a partial vertical cross-sectional view sequentially illustrating the operation process of the syringe (first embodiment) of the present invention. FIG. 6 is an exploded perspective view showing the positional relationship between the syringe body and the valve body in the syringe of the present invention (first embodiment). FIG. 7 is a perspective view of the valve body shown in FIG. 6 as viewed from the distal end side. FIG. 8 is a partial longitudinal sectional view showing an unused state of the syringe (second embodiment) of the present invention. FIG. 9 is an exploded perspective view showing the positional relationship between the syringe body and the valve body in the syringe (second embodiment) of the present invention.

Hereinafter, the syringe of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIGS. 1 to 5 are partial longitudinal sectional views sequentially showing the operation process of the syringe of the present invention (first embodiment), and FIG. 6 is a syringe body and a valve body in the syringe of the present invention (first embodiment). FIG. 7 is a perspective view of the valve body shown in FIG. 6 as viewed from the distal end side. In the following, for convenience of explanation, the upper side in FIGS.

As shown in FIG. 1 to FIG. 5, the syringe 1 is a two-chamber prefilled syringe in which a drug 11 and a liquid 12 for dissolving the drug 11 are previously separated and housed in two chambers. The syringe 1 includes an elongated syringe body 2, a first gasket 3a and a second gasket 3b that can slide in the syringe body 2, a plunger 4 that moves and operates the first gasket 3a, The nozzle 5 arrange | positioned at the front end side of the syringe main body 2, and the switching means 6 arrange | positioned between the syringe main body 2 and the nozzle 5 are provided. Hereinafter, the configuration of each unit will be described.

As shown in FIG. 6, the syringe body 2 includes a first outer cylinder 21a having a bottomed cylindrical shape and a second outer cylinder 21b having a bottomed cylindrical shape, and these outer cylinders are parallel to each other. Adjacent, that is, connected or integrally formed in a side-by-side arrangement.

In the present embodiment, the cross section of the first outer cylinder 21a and the cross section of the second outer cylinder 21b have the same shape and size. The total length of the first outer cylinder 21a and the total length of the second outer cylinder 21b are also the same. As described above, the overall shape of the first outer cylinder 21a and the overall shape of the second outer cylinder 21b are the same, so that the entire shape of the syringe body 2 is flat. Thereby, the syringe body 2 occupying most of the syringe 1 is small and easy to grip, and as a result, the syringe 1 can be stably gripped and used.

As shown in FIGS. 1 and 2, the first outer cylinder 21a can use the internal space as a first space 22a in which the first gasket 3a and the medicine 11 are stored. The inner space of the second outer cylinder 21b can be used as the second space 22b in which the second gasket 3b and the liquid 12 are stored. As a result, the first space 22a and the second space 22b are arranged side by side along a direction orthogonal to the longitudinal direction of the syringe body 2, and each of the first outer cylinder 21a and the second outer cylinder 21b is arranged. The tube walls 211 are separated from each other.

A mouth portion 23a penetrating in the thickness direction is formed at the bottom of the first outer cylinder 21a. As will be described later, the mouth portion 23a also functions as an inflow port through which the liquid 12 in the second space 22b flows (see FIG. 3), and the drug 11 in the first space 22a and the liquid 12 that has flowed in It also functions as a discharge port through which the chemical solution 13 generated by mixing is discharged (see FIG. 5). The mouth portion 23a is formed at a position that is eccentric with respect to the central axis of the first outer cylinder 21a.

A mouth portion 23b penetrating in the thickness direction is formed at the bottom of the second outer cylinder 21b. As will be described later, the mouth portion 23b functions as a discharge port through which the liquid 12 in the second space 22b is discharged toward the first space 22a (see FIG. 3). The mouth portion 23b is also formed at a position that is eccentric with respect to the central axis of the second outer cylinder 21b.

As shown in FIG. 6, on the outer periphery of the distal end of the syringe body 2, there are disk-shaped flanges 24 arranged in parallel to the direction orthogonal to the longitudinal direction, the first outer cylinder 21a and the second outer cylinder 21b. And are integrally formed. The flange 24 is a portion that fits into the operation member 8 of the switching means 6.

Further, as shown in FIG. 1 (the same applies to FIGS. 2 to 5), a plate-like flange 25 arranged parallel to the direction orthogonal to the longitudinal direction is also provided on the outer periphery of the proximal end of the syringe body 2 in the first direction. The outer cylinder 21a and the second outer cylinder 21b are integrally formed. When the plunger 4 is moved and operated relative to the syringe body 2, the operation can be performed with a finger placed on the flange 25.

Examples of the constituent material of the syringe body 2 include polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, Various resins such as polyesters such as polyethylene terephthalate and polyethylene naphthalate, butadiene-styrene copolymers, and polyamides (for example, nylon 6,

nylon

6,6, nylon 6,10, nylon 12) can be mentioned. Resin such as polypropylene, cyclic polyolefin, polyester, and poly- (4-methylpentene-1) is preferable because it is easy to mold. In addition, it is preferable that the constituent material of the syringe main body 2 is substantially transparent in order to ensure internal visibility.

As shown in FIG. 1, a first gasket 3a made of a cylindrical elastic body is inserted into the first space 22a of the first outer cylinder 21a. The first gasket 3a can slide while its outer peripheral surface 31 is in close contact with the inner peripheral surface 212 of the first outer cylinder 21a. As a result, as shown in FIGS. 1 to 5, even when the first gasket 3a moves, the liquid tightness of the portion of the first space 22a closer to the tip than the first gasket 3a is reliably maintained. be able to.

Also, a second gasket 3b made of a cylindrical elastic body is inserted into the second space 22b of the second outer cylinder 21b. The second gasket 3b can also slide while its outer peripheral surface 31 is in close contact with the inner peripheral surface 212 of the second outer cylinder 21b. As a result, as with the first gasket 3a, even if the second gasket 3b moves, the liquid tightness of the portion of the second space 22b on the tip side of the second gasket 3b is reliably maintained. Can do.

The constituent materials of the first gasket 3a and the second gasket 3b are not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber are used. And elastic materials such as various thermoplastic elastomers such as polyurethane, polyester, polyamide, olefin, and styrene, or a mixture thereof.

A plunger 4 is connected to the base end of the first gasket 3a. By operating the plunger 4, the first gasket 3a can be moved. Therefore, the suction of the liquid 12 from the second space 22b to the first space 22a and the liquid 13 from the first space 22a can be performed. The discharge to the outside can be performed easily and reliably.

The plunger 4 includes a main body portion 41 having a rod shape and a plate-like flange 42 formed at the base end of the main body portion 41. The front end of the main body 41 is connected to the first gasket 3a by, for example, screwing or fitting. The flange 42 functions as a gripping part that is gripped with a finger when the plunger 4 is pulled in the proximal direction, and functions as a pressing part that is pressed with a finger when the plunger 4 is pressed in the distal direction.

In addition, it does not specifically limit as a constituent material of the plunger 4, For example, the same constituent material as the constituent material of the syringe main body 2 can be used.

As shown in FIG. 1, the medicine 11 is accommodated in a portion of the first space 22a on the tip side of the first gasket 3a. The drug 11 may be anything as long as it is normally used as an injection. For example, protein drugs such as antibodies, peptide drugs such as hormones, nucleic acid drugs, cell drugs, blood products, various infectious diseases are prevented. Vaccines, anticancer agents, anesthetics, narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, heparin, glucose injections such as glucose, electrolyte correction injections such as sodium chloride and potassium lactate, vitamins, Examples include fat emulsions, contrast agents, and stimulants.

The drug 11 may be in any form such as powder, solid including granule, liquid, etc., but powder is preferred. Thereby, the chemical | medical agent 11 can be mix | blended and dissolved easily in the liquid 12, and the chemical | medical solution 13 is produced | generated.

Further, the liquid 12 is accommodated in a portion of the second space 22b on the tip side of the second gasket 3b. The liquid 12 is not particularly limited as long as it can be injected into blood vessels, intradermally, and subcutaneously. Examples thereof include physiological saline, glucose solution, various Ringer's solutions, water for injection, and electrolyte solution. .

The switching means 6 switches the communication pattern of the first space 22a, the second space 22b, and the nozzle 5, that is, the first state shown in FIG. 1 and the second state shown in FIGS. The syringe 1 is switched to the third state shown in FIGS. In the first state, the first space 22a, the second space 22b, and the nozzle 5 are blocked from each other. In the second state, the first space 22a and the second space 22b communicate with each other, and the nozzle 5 is blocked from the first space 22a and the second space 22b. In the third state, the first space 22 a communicates with the nozzle 5, and the second space 22 b is blocked from the first space 22 a and the nozzle 5.

As shown in FIGS. 1 and 6, the switching means 6 includes a valve body 7 formed of a disk-shaped member, and an operation member (rotation operation unit) 8 that rotates the valve body 7 about its central axis 71. It consists of and.

The valve element 7 has the same size as the flange 24 of the syringe body 2 and is disposed concentrically with the flange 24. Further, the valve body 7 can slide around the central axis 71 while the proximal end surface 72 thereof is in close contact with the distal end surface 241 of the flange 24. In addition, the process which reduces the sliding resistance of the valve body 7 and the flange 24 may be performed. The treatment method is not particularly limited, and examples thereof include a method of coating the tip surface 241 of the flange 24 with a fluorine-based resin such as polytetrafluoroethylene (PTFE), a method of applying a lubricant such as silicone, and the like. It is done.

As shown in FIG. 6, a groove 74 is formed in the proximal end surface 72 of the valve body 7. The groove 74 forms a single letter that passes through the central axis 71. The depth of the groove 74 is smaller than the thickness of the valve body 7.

Further, the valve body 7 is formed with a through hole 75 penetrating the valve body 7 in the thickness direction at a position different from the groove 74, that is, on the perpendicular bisector of the groove 74 in this embodiment.

As shown in FIG. 7, a groove 77 communicating with the through-hole 75 and

grooves

78 and 79 are formed on both sides of the groove 77 on the distal end surface 76 of the valve body 7. Each of the grooves 77 to 79 has a single letter shape, and the depth thereof is smaller than the thickness of the valve body 7. The groove 77 functions as a flow path through which the chemical liquid 13 passes when flowing down from the first space 22a toward the nozzle 5 (see FIG. 5).

The constituent material of the valve body 7 is not particularly limited, and for example, the same constituent material as that of the first gasket 3a and the second gasket 3b can be used.

As shown in FIG. 1, the operation member 8 for rotating the valve body 7 is composed of a bottomed cylindrical member. The operating member 8 has a claw 81 formed in a ring shape along the circumferential direction on the inner peripheral portion thereof. The claw 81 engages with a groove 213 formed in each tube wall 211 of the first outer cylinder 21a and the second outer cylinder 21b of the syringe body 2. Thereby, the operation member 8 will be rotatably supported by the syringe body 2.

Further, engaging

portions

84 and 85 that engage with the

grooves

78 and 79 of the valve body 7 are formed on the bottom portion of the operation member 8 so as to protrude. Thereby, the valve body 7 is fixed with respect to the operation member 8, and when the operation member 8 is rotated, the valve body 7 can also rotate in conjunction with the rotation. Other methods for fixing the valve body 7 include, for example, a method using adhesion (adhesion with an adhesive or a solvent), a method using fusion (thermal fusion, high-frequency fusion, ultrasonic fusion, etc.), and the like. It is done.

Furthermore, a nozzle 5 protruding toward the distal end is integrally formed at the center of the bottom of the operation member 8. The nozzle 5 has a tubular shape and communicates with the groove 77 of the valve body 7. Thereby, the chemical | medical solution 13 which passed the groove | channel 77 can be discharged.

In the switching means 6 configured as described above, the valve body 7 is also rotated by rotating the operation member 8, and the groove 74 and the through-hole 75 of the valve body 7 and the first outer cylinder of the syringe body 2. The positional relationship between 21a (first space 22a) and second outer cylinder 21b (second space 22b) changes (see FIG. 6). Thereby, any one of the first state, the second state, and the third state can be taken. This will be described in detail.

The syringe 1 is in the first state shown in FIG. 1 when not in use. In this first state, the groove 74 and the through hole 75 of the valve body 7 and the mouth portion 23a of the first outer cylinder 21a and the mouth portion 23b of the second outer cylinder 21b are shifted around the central axis 71. Yes. Accordingly, the mouth portion 23a of the first outer cylinder 21a and the mouth portion 23b of the second outer cylinder 21b are collectively covered and sealed from the distal end side by the proximal end surface 72 of the valve body 7. Thereby, the 1st space 22a, the 2nd space 22b, and the nozzle 5 will be interrupted | blocked reliably.

When the operation member 8 is rotated in a predetermined direction (the direction of arrow A in FIG. 2) from the first state, the second state shown in FIG. 2 is obtained. In this second state, the mouth portion 23a of the first outer cylinder 21a and the mouth portion 23b of the second outer cylinder 21b face the groove 74 of the valve body 7. Thereby, the first space 22a and the second space 22b communicate with each other through the groove 74. At this time, the nozzle 5 remains blocked from the first space 22a and the second space 22b.

When the operation member 8 is rotated in the opposite direction (in the direction of arrow B in FIG. 4) from the second state, the third state shown in FIG. 4 is obtained. In the third state, the opening 23 a of the first outer cylinder 21 a faces the through hole 75 of the valve body 7. Thereby, the first space 22 a and the nozzle 5 communicate with each other through the through hole 75 and the groove 77. At this time, the mouth portion 23 b of the second outer cylinder 21 b is covered and sealed by the proximal end surface 72 of the valve body 7. As a result, the second space 22b is blocked from the first space 22a and the nozzle 5.

Thus, for the two-chamber prefilled syringe in which the first space 22a and the second space 22b such as the syringe 1 are arranged in parallel, the switching means 6 having the above-described configuration is suitable as a switching means for switching the communication pattern. I can say that.

The operation member 8 may be provided with a marker indicating whether the switching means 6 is in the first state to the third state.

The constituent materials of the nozzle 5 and the operation member 8 are not particularly limited, and for example, the same constituent materials as the constituent materials of the syringe body 2 can be used.

The syringe 1 is used with a puncture needle 20 attached to a nozzle 5. The puncture needle 20 includes a hollow needle 201, a hub 202 fixed to the proximal end portion of the hollow needle 201, and a cap 203 that covers the hollow needle 201.

The hollow needle 201 has a sharp needle tip 204 at its tip. For example, the surface of the living body can be punctured with the needle tip 204. The hollow needle 201 communicates with the nozzle 5 when the puncture needle 20 is attached to the nozzle 5. Thereby, the chemical | medical solution 13 which passed the nozzle 5 can be discharged | emitted, and it can administer to a biological body (refer FIG. 5).

The hub 202 is composed of a member having a bottomed cylindrical shape, and supports and fixes the proximal end portion of the hollow needle 201 at the bottom. Further, the hub 202 has an inner diameter so that the inner peripheral portion 205 can be liquid-tightly fitted to the outer peripheral portion 51 of the nozzle 5. This prevents the puncture needle 20 attached to the nozzle 5 from being unintentionally detached.

The cap 203 is composed of a member having a bottomed cylindrical shape, and is detachably attached to the hub 202, and can cover the hollow needle 201 up to the needle tip 204 in the attached state. Thereby, erroneous puncture at the needle tip 204 can be reliably prevented.

Note that the constituent material of the hollow needle 201 is not particularly limited, and examples thereof include stainless steel, aluminum or aluminum alloy, and metal material such as titanium or titanium alloy. Moreover, it does not specifically limit as a constituent material of the hub 202 and the cap 203, respectively, For example, the same constituent material as the constituent material of the syringe main body 2 can be used.

Next, an operation method (usage method) of the syringe 1 will be described.
[1] As shown in FIG. 1, a puncture needle 20 is attached to the nozzle 5, and an unused syringe 1 is prepared. The syringe 1 is in the first state. As described above, in the first state, the first space 22a, the second space 22b, and the nozzle 5 are blocked from each other.

Further, the first gasket 3a is positioned so as to be shifted to the tip side from the second gasket 3b. The amount of displacement of the first gasket 3a with respect to the second gasket 3b is secured to such an extent that the first gasket 3a can be moved in consideration of the movement of the first gasket 3a in the proximal direction in the subsequent operation. . For example, when the first gasket 3a is located at the same position as the second gasket 3b, the entire length of the syringe body 2 becomes longer by the amount of displacement, but due to the positional relationship described above, the syringe body 2 It is possible to prevent the overall length of the syringe from becoming long, and thus contribute to the downsizing of the syringe 1.

[2] Next, the operation member 8 is rotated in the direction of arrow A from the state shown in FIG. Thereby, as shown in FIG. 2, it will be in a 2nd state. As described above, in the second state, the first space 22a and the second space 22b communicate with each other through the groove 74 of the valve body 7, and the nozzle 5 is connected to the first space 22a and the second space 22b. It is cut off from.

[3] Next, the flange 42 of the plunger 4 is gripped from the state shown in FIG. 2, and the plunger 4 is pulled in the proximal direction. By this pulling operation, the first gasket 3a moves in the proximal direction, so that the pressure in the first space 22a decreases. Thereby, since the pressure in the second space 22b is also reduced, the second gasket 3b is sucked and moved in the distal direction. The liquid 12 in the second space 22b is pushed out of the second space 22b by the second gasket 3b, passes through the groove 74 of the valve body 7, and flows into the first space 22a. And the chemical | medical agent 11 and the liquid 12 mix in the 1st space 22a, and the chemical | medical solution 13 is produced | generated.

In addition, in order to promote mixing with the chemical | medical agent 11 and the liquid 12, you may perform the pumping operation which makes the plunger 4 reciprocate. As a result, the mixture of the drug 11 and the liquid 12 can be moved back and forth between the first space 22a and the second space 22b, thereby efficiently promoting the mixing. be able to.

[4] Next, the operation member 8 is rotated in the arrow B direction from the state shown in FIG. Thereby, as shown in FIG. 4, it will be in a 3rd state. As described above, in the third state, the first space 22 a and the nozzle 5 communicate with each other through the through hole 75 of the valve body 7, and the second space 22 b extends from the first space 22 a and the nozzle 5. Blocked.

[5] Next, the cap 203 is removed from the state shown in FIG. 4 (see FIG. 5). Then, for example, an index finger and a middle finger are hung on the flange 25 of the syringe body 2, and a thumb is hung on the flange 42 of the plunger 4. Since the syringe 1 is a two-chamber type prefilled syringe in which the first space 22a and the second space 22b are arranged side by side in the horizontal direction, the conventional two spaces are arranged in the vertical direction. Unlike the prefilled syringe of the mold, the total length in the state before use is shortened and miniaturized. Thereby, the distance between the flange 25 of the syringe body 2 and the flange 42 of the plunger 4 is such that a finger can easily be hung.

Next, while holding the syringe 1, the surface of the living body is punctured with the needle tip 204 of the hollow needle 201, and in this state, the plunger 4 is pressed toward the distal end with the thumb. By this pressing operation, as shown in FIG. 5, the first gasket 3 a moves in the distal direction, and the chemical solution 13 in the first space 22 a passes through the nozzle 5 and is discharged from the hollow needle 201. The discharged chemical solution 13 is administered to the living body.

Second Embodiment
FIG. 8 is a partial longitudinal sectional view showing an unused state of the syringe of the present invention (second embodiment), and FIG. 9 shows the positional relationship between the syringe body and the valve body in the syringe of the present invention (second embodiment). It is a disassembled perspective view shown.

Hereinafter, the second embodiment of the syringe of the present invention will be described with reference to these drawings. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.
This embodiment is the same as the first embodiment except that an airtightness maintaining means is provided.

The syringe 1 of this embodiment shown in FIG. 8 maintains the airtightness (liquid tightness) between the distal end surface 241 of the syringe body 2 and the proximal end surface 72 of the valve body 7 when the operation member 8 is rotated. Airtightness maintaining means 30 is provided. The airtightness maintaining means 30 can reliably prevent the liquid 12 and the chemical liquid 13 from leaking from between the syringe body 2 and the valve body 7 at least during the rotational operation of the operation member 8.

As shown in FIGS. 8 and 9, the airtightness maintaining means 30 includes a protrusion 26 that is formed to protrude from the distal end surface 241 of the syringe body 2, and a groove 73 that is formed on the proximal end surface 72 of the valve body 7. Has been.
In the syringe body 2, the mouth part 23a is disposed on the central axis of the first outer cylinder 21a, and the mouth part 23b is disposed on the central axis of the second outer cylinder 21b. The protrusion 26 is formed in a ring shape (annular shape) around the central axis 71, that is, around the rotation axis of the operation member 8, outside the

mouth portions

23 a and 23 b. Moreover, as shown in FIG. 8, the cross-sectional shape of the protrusion 26 is an equilateral triangle in the illustrated configuration.

Further, in the valve body 7, the groove 74 and the through hole 75 are respectively arranged corresponding to the

mouth portions

23a and 23b arranged as described above. The groove 73 is formed in a ring shape around the central axis 71 outside the groove 74 and the through hole 75. Further, as shown in FIG. 8, the cross-sectional shape of the groove 73 is an equilateral triangle in the illustrated configuration, and its size is slightly smaller than the cross-sectional size of the protrusion 26. As a result, when the syringe body 2 and the valve body 7 are assembled, the protrusion 26 is inserted in close contact with the groove 73, so that the airtightness between the syringe body 2 and the valve body 7 is reliably maintained. Be drunk.

In the present embodiment, the “projection” and the “groove” constituting the airtightness maintaining means 30 are each formed in the distal end surface 241 of the syringe body 2 and the groove is the proximal end surface 72 of the valve body 7. However, the present invention is not limited to this. For example, the protrusion may be formed on the proximal end surface 72 of the valve body 7 and the groove may be formed on the distal end surface 241 of the syringe body 2.

Further, the cross-sectional shapes of the protrusions 26 and the grooves 73 are equilateral triangles in the present embodiment, but are not limited thereto, and may be, for example, a quadrangle, a semicircle, or the like.

As mentioned above, although the syringe of this invention was demonstrated about embodiment of illustration, this invention is not limited to this, Each part which comprises a syringe substitutes the thing of the arbitrary structures which can exhibit the same function. can do. Moreover, arbitrary components may be added.

Further, the syringe of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

In addition, the syringe body has the same overall shape of the first outer cylinder and the second outer cylinder in the illustrated configuration, but is not limited thereto, and is different. Also good.

In the illustrated configuration, the plunger is connected to the first gasket, but the plunger is not limited to this and may be connected to the second gasket. In this case, the pressure in the second space can be increased by gripping the plunger in the second state and moving the second gasket in the distal direction. Also by this operation, the liquid in the second space flows into the first space and is mixed with the medicine to generate a medicine.

Alternatively, the chemical solution generated in the first space may be transferred to the second space, and then the chemical solution may be discharged from the second space in a state where the second space and the nozzle communicate with each other.

The syringe of the present invention is an elongated syringe body, and has a first space and a second space which are arranged in a line along a direction orthogonal to the longitudinal direction and partitioned from each other. A syringe body, a nozzle that is disposed on the distal end side of the syringe body, communicates with the inside of the syringe body, is inserted into the first space, and can slide along the longitudinal direction of the syringe body. A gasket, a second gasket that is inserted into the second space and that can slide along the longitudinal direction of the syringe body, and a portion of the first space that is closer to the tip than the first gasket; The communication pattern of the stored medicine, the liquid stored in the tip side of the second space with respect to the second gasket, and the communication pattern of the first space, the second space, and the nozzle is switched. With switching means The switching means communicates the first state in which the first space, the second space, and the nozzle are blocked from each other, the first space, and the second space, and the nozzle Is communicated between the first space and the second space, one of the first space and the second space, and the nozzle, The space is configured to switch to a third state where the space is blocked from the one space and the nozzle.

Therefore, since the first space and the second space are arranged side by side, even if the plunger is connected to the first gasket or the second gasket, the total length in the state before use is shortened. And miniaturization can be achieved. Accordingly, it is easy to hold the syringe body to the plunger with one hand, that is, to hang the index finger and the middle finger on the syringe body and to hang the thumb on the plunger. And the pressing operation with respect to a plunger can be performed easily. Therefore, the syringe of the present invention has industrial applicability.

Claims

A syringe body having a long shape, the syringe body having a first space and a second space that are arranged side by side along the direction orthogonal to the longitudinal direction and partitioned from each other,
A nozzle disposed on the distal end side of the syringe body and communicating with the inside of the syringe body;
A first gasket inserted into the first space and slidable along the longitudinal direction of the syringe body;
A second gasket inserted into the second space and slidable along the longitudinal direction of the syringe body;
A medicine housed in a portion on the tip side of the first gasket in the first space;
A liquid stored in a portion of the second space on the tip side of the second gasket;
Switching means for switching a communication pattern between the first space, the second space, and the nozzle;
The switching means includes a first state in which the first space, the second space, and the nozzle are blocked from each other, and the first space and the second space communicate with each other. The second state that is blocked from the first space and the second space, one of the first space and the second space, and the nozzle communicate with each other, and the other space. The syringe is configured to switch to a third state that is blocked from the one space and the nozzle.
The switching means is composed of a plate member disposed in parallel with a direction orthogonal to the longitudinal direction of the syringe body between the syringe body and the nozzle, and a groove formed on a base end surface thereof, and the plate member A valve body having a through hole formed through the thickness direction thereof, and a rotation operation unit that rotates the valve body about its central axis,
By operating the rotation operation unit, the positional relationship between the groove and the through hole, the first space, and the second space is changed, and in the first state, the base of the valve body is changed. The first space and the second space are sealed at the end face, and in the second state, the first space and the second space communicate with each other through the groove, and the third space In this state, the one space and the nozzle communicate with each other through the through hole, and the other space is sealed at the base end surface of the valve body.
The syringe according to claim 2, further comprising an airtightness maintaining means for maintaining an airtightness between the syringe body and the valve body when the rotation operation unit is operated.
The airtightness maintaining means includes a protrusion formed in a ring shape around the central axis on one surface of the distal end surface of the syringe body and the proximal end surface of the valve body, and the central axis on the other surface. The syringe according to claim 3, wherein the syringe is formed in a ring shape around and a groove into which the protrusion is inserted in close contact.
In the second state, the pressure in the first space is reduced by moving the first gasket in the proximal direction, or the second gasket is moved in the distal direction. The syringe according to claim 1, wherein when the pressure in the second space is increased, the liquid in the second space flows into the first space and is mixed with the drug, thereby generating a drug solution.
The syringe body is formed by connecting or integrally forming two cylinders, and the inner space of one of the two cylinders functions as the first space, The syringe according to claim 1, wherein an internal space of the cylindrical body functions as the second space.
The syringe according to claim 1, further comprising a plunger connected to one of the first gasket and the second gasket and operating to move the connected gasket.
The said nozzle is comprised so that mounting | wearing of the said hub of the puncture needle which has the hollow needle which has a sharp needle point at the front-end | tip, and the hub fixed to the base end part of this hollow needle is possible. Syringe.