WO2011132657A1 - Liquid-medicine dosing device - Google Patents

Abstract

A liquid-medicine dosing device comprises a main body, a syringe for taking in and discharging a liquid medicine, and a vial in which a drug is contained. The main body of the liquid-medicine dosing device comprises: a three-way stopcock; a tube which has one end thereof connected to a third port of the three-way stopcock and the other end connected to a puncture needle; a filter which is detachably attached to a first port of the three-way stopcock, and allows a gas to flow and blocks bacteria; and a connection tool and a linking part which are provided at a second port of the three-way stopcock, and are connected to the vial.

Description

Chemical administration device

The present invention relates to a drug solution administration device.

For example, when a patient self-injects a drug solution such as a blood product, the drug may be dissolved or diluted with a liquid, and the drug solution may be sucked with a syringe and used. These operations are performed as follows.

First, using a double-ended needle or an adapter with a hollow needle, connect the drug container containing the drug to one end of the double-ended needle or hollow needle, and connect the liquid container containing the liquid to the other end. Then, the liquid in the liquid container is transferred into the drug container. Thereby, the chemical | medical agent in a chemical | medical agent container is melt | dissolved or diluted with a liquid, and a chemical | medical solution is obtained (for example, refer patent document 1).

Next, remove the adapter from the drug container, use a syringe with a puncture needle with a sharp needle tip at the tip, pierce the puncture needle through the plug of the drug container, and remove the drug solution in the drug container from the syringe. Suction and fill into the cylinder.

However, the method using such a conventional adapter and a syringe to which a puncture needle is connected has a drawback that the operation is complicated and takes time and effort.

Also, since an operation for puncturing the plug of the drug container is necessary, there is a risk that the finger may be accidentally punctured with the puncture needle during the operation.

JP 2005-516696 A

An object of the present invention is to provide a drug administration device that can easily and quickly dissolve or dilute a drug to obtain a drug solution and allow the drug solution to flow out of a puncture needle.

In order to achieve the above object, the present invention provides:
A first port; a second port; and a third port. The first port, the second port, and the third port of the first port, the second port, and the third port. A multiway cock that can take a first state in which the first port communicates with the second port and a second state in which the first port communicates with the third port;
A connecting device provided in the second port;
A first container in which a medicine connected to the second port via the connection device is stored;
A tube having one end connected to the third port and a puncture needle connected to the other end;
A second container that is detachably connected to the first port, encloses a liquid that dissolves or dilutes the drug, and is capable of inhaling and discharging the liquid;
The first container is connected to the connecting device, the second container is connected to the first port, and the liquid is discharged from the second container in a state where the multiway cock is in the first state. After being introduced into the first container and dissolving or diluting the drug to obtain a drug solution, the drug solution is inhaled from the first container into the second container,
Next, the multi-way cock is in the second state, the chemical solution is discharged from the second container, and the chemical solution is configured to flow out of the puncture needle through the tube. It is an instrument.

In order to achieve the above object, the present invention includes a first port, a second port, and a third port, and the first port, the second port, and the third port. A multiway stopcock capable of taking a first state in which the first port and the second port are in communication with each other and a second state in which the first port and the third port are in communication with each other ,
A connecting device provided in the second port;
A first container in which a medicine connected to the second port via the connection device is stored;
A tube having one end connected to the third port and a puncture needle connected to the other end;
A filter that is detachably attached to the first port and that allows gas to pass but bacteria not to pass through;
A second container that is detachably connected to the first port, encloses a liquid that dissolves or dilutes the drug, and is capable of inhaling and discharging the liquid;
With the multi-way stopcock in the first state, with the filter attached to the first port, connect the first container to the connection device,
Then, removing the filter from the first port, connecting the second container to the first port,
Next, after introducing the liquid from the second container into the first container and dissolving or diluting the drug to obtain a drug solution, the drug solution is inhaled from the first container into the second container,
Next, the multi-way cock is in the second state, the chemical solution is discharged from the second container, and the chemical solution is configured to flow out of the puncture needle through the tube. It is an instrument.

In the medicinal-solution administration device of the present invention, the filter has a housing that is detachably attached to the first port, and a filter member that is installed in the housing and through which gas passes but bacteria do not pass. And
The inside of the first container has a negative pressure, and when the first container is connected to the second port via the connecting device, the air that has passed through the filter is introduced into the first container. It is preferable that it is comprised so that.

In the medicinal-solution administration device of the present invention, the first port and the third port are arranged on a straight line, and the second port protrudes to the side of the first port. It is preferable.

In the drug solution administration device of the present invention, the puncture needle is preferably a winged needle.

Further, in the drug solution administration device of the present invention, it is provided in the vicinity of the puncture needle in the middle of the tube, and has an easy-to-break portion that breaks more easily than the surrounding portion,
It is preferable that the breakable portion is broken so that the first portion including the puncture needle can be separated from the second portion other than the first portion.

In the medicinal-solution administration device of the present invention, it is preferable that the easily breakable portion is provided separately from the puncture needle and in a region within 10 cm from the proximal end of the puncture needle of the tube.

Further, in the drug solution administration device according to the present invention, the tube includes a distal tube connected to the puncture needle, a proximal tube positioned proximal to the distal tube, the distal tube, and the A connecting member that connects the proximal tube,
It is preferable that the breakable part is formed in the connecting member.

In the drug solution administration device of the present invention, the connecting member includes a distal end portion connected to the distal end side tube, a proximal end portion connected to the proximal end tube, the distal end portion, and the proximal end portion. Having an intermediate part for connecting
The intermediate part has a thin part thinner than the distal end part and the base end part,
It is preferable that the thin portion constitutes the easily breakable portion.

Further, in the drug solution administration device of the present invention, the multi-way stopcock has a cylindrical shape, and a cylindrical portion in which the first port, the second port, and the third port are respectively disposed on an outer peripheral portion thereof. A cock having a cylindrical body portion that is rotatably inserted into the cylindrical portion and has flow paths corresponding to the first port, the second port, and the third port, respectively. And by turning the cock, the first state and the second state can be taken,
It is preferable to further include a detachment mechanism that prevents the connection tool from being detached from the second port in the first state, and allows the connection tool to be detached from the second port in the second state. .

Further, in the drug solution administration device of the present invention, the connection device has a tubular portion for connection to the second port,
The detachment mechanism is provided on the cock with a protruding piece formed on the outer peripheral portion of the tubular portion and on a circumference centering on the central axis of the trunk portion in conjunction with the turning operation of the cock. An engaging piece that moves,
In the first state, the engagement piece engages with the protruding piece to prevent the connection tool from being detached from the second port, and in the second state, the engagement is released. It is preferable that the connecting device can be detached from the second port.

Further, in the drug solution administration device of the present invention, a pair of the projecting pieces are provided on opposite sides via the central axis of the second port,
It is preferable that a pair of the engaging pieces are provided corresponding to the pair of protruding pieces.

FIG. 1 is a side view (partially sectional view) showing a first embodiment of a drug solution administration device of the present invention. FIG. 2 is a perspective view showing a drug solution administration device body of the drug solution administration device shown in FIG. FIG. 3 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 4 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 5 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 6 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 7 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 8 is a side view for explaining the procedure for using the drug solution administration device shown in FIG. 1. FIG. 9 is a perspective view showing the vicinity of the puncture needle of the drug solution administration device (second embodiment) of the present invention. 10 is a schematic cross-sectional view of a connecting member in the drug solution administration device shown in FIG. 9. 11 is a perspective view showing a separated state in the vicinity of the puncture needle of the drug solution administration device shown in FIG. FIG. 12 is a perspective view sequentially illustrating the operation (from the first state to the second state) of the multiway cock provided in the drug solution administration device (third embodiment) of the present invention. FIG. 13 is a perspective view sequentially illustrating the operation (from the first state to the second state) of the multiway cock provided in the drug solution administration device (third embodiment) of the present invention. 14 is a cross-sectional view taken along line AA in FIG. FIG. 15 is a cross-sectional view taken along line BB in FIG.

Hereinafter, the drug solution administration device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a side view (partially sectional view) showing a first embodiment of a drug solution administration device of the present invention, FIG. 2 is a perspective view showing a drug solution administration device body of the drug solution administration device shown in FIG. FIG. 8 is a side view for explaining the procedure for using the drug solution administration device shown in FIG.

In the following, the right side in FIG. 1, FIG. 3 to FIG. 6 and FIG. 8 is the “front end”, the left side is the “base end (rear end)”, and the left side in FIG. Is described as “base end”.

The drug solution administration device 1 of the present embodiment shown in these drawings is a device used when performing self-injection of a drug solution. As shown in FIGS. 1 and 2, the drug solution administration device 1 is a drug solution administration device body 2. And a syringe 6 as a second container (inhalation / discharge device) capable of inhaling and discharging liquid, and a vial (drug container) 7 as a first container in which a medicine is stored.

Note that the first container is not limited to a vial as long as it is a container in which a medicine is stored, and other examples include an ampoule. In addition, the second container is not limited to a syringe as long as it can inhale and discharge liquid, and other examples include a container made of an elastic body or the like. Moreover, the chemical | medical solution administration instrument 1 can be used also when not only self-injection but medical workers, such as a doctor and a nurse, inject with respect to a patient, for example. Hereinafter, each component will be sequentially described.

The drug solution administration device body 2 includes a three-way stopcock (multi-way stopcock) 3, a tube 4, a puncture needle 5, a filter 8 through which gas passes but bacteria do not pass, and a connection device 9 to which a vial 7 is connected. Part 11.

The three-way cock 3 includes a main body 31 and a cock 35.
The main body 31 is formed on the outer periphery of the cylindrical portion 32 and the cylindrical portion 32, and the first port 331, the second port 332, and the third port that protrude outward in the radial direction of the cylindrical portion 32. 333.

The first port 331, the second port 332, and the third port 333 each have a tubular shape and are arranged at equal angular intervals, that is, at an angle of 90 °. In this case, the first port 331 and the third port 333 are arranged at an angle of 180 °, that is, arranged on a straight line. Further, the second port 332 protrudes toward the side of the first port 331 and the second port 332, that is, an angle of 90 ° with respect to each of the first port 331 and the second port 332. Are arranged apart from each other. The flow paths 341, 342, and 343 formed inside the first port 331, the second port 332, and the third port 333 are respectively located in the lumen 320 of the cylindrical portion 32 at the same height position. Communicate.

Further, a flange-like protrusion 334 is formed on the outer peripheral portion of the base end of the first port 331. The shape of the protrusion 334 is non-circular when viewed from the axial direction of the first port 331, that is, has a shape in which one of the two orthogonal directions is longer than the other. The screw adapter 63 can be screwed with the thread formed on the lock adapter 63 and the thread formed on the housing 81 of the filter 8. The protrusion 334 is not limited to the protrusion 334 as long as it can be screwed with the thread, and may be a thread, for example.

The cock 35 has a trunk portion 36 and a lever 38 formed on the upper portion of the trunk portion 36. The body portion 36 has a columnar shape or a cylindrical shape (columnar shape in the illustrated configuration), and is rotatably inserted into the inner cavity 320 of the cylindrical portion 32 with airtightness or liquidtightness.

In the body portion 36, flow paths 371, 372, and 373 corresponding to the flow paths 341, 342, and 343 of the first port 331, the second port 332, and the third port 333 are formed in a T shape. ing. That is, three flow paths 371, 372, and 373 extending in the radial direction of the body part 36 at an angle of 90 ° are communicated with each other in the vicinity of the center part of the body part 36 inside the body part 36. It is formed to do.

The flow paths 371, 372, and 373 coincide with the flow paths 341, 342, and 343 of the first port 331, the second port 332, and the third port 333 with the cock 35 inserted into the main body 31. It is formed at a height position. Each of the flow paths 371, 372, and 373 is opened on the outer peripheral surface of the body portion 36 to form an opening.

The lever 38 is formed to protrude in the opposite direction to the flow path 372 at the upper portion of the body portion 36, that is, at a portion protruding above the cylindrical portion 32 in the body portion 36. The lever 38 is gripped with fingers, and the cock 35 is rotated.

The three-way stopcock 3 is in the first state in which the first port 331 and the second port 332 communicate when the lever 38 is positioned on the third port 333 side as shown in FIG. As shown in FIG. 8, when positioned on the second port 332 side, the first port 331 and the third port 333 communicate with each other in a second state. Although not shown, when the lever 38 is positioned on the first port 331 side, the second port 332 and the third port 333 communicate with each other, and when the lever 38 is positioned on the opposite side of the second port 332. The first port 331, the second port 332, and the third port 333 communicate with each other.

The constituent material of each part of the three-way stopcock 3 is not particularly limited. For example, polyolefin such as polypropylene, polycarbonate, or the like can be used.

The connecting device 9 is provided at the second port 332 of the three-way stopcock 3.
The connecting device 9 includes a main body 91 and a hollow needle 92 that can be pierced with a stopper 72 of a vial 7 described later. The main body portion 91 has a bottomed cylindrical holder 911 surrounding the hollow needle 92 and a tubular portion 912 formed at the bottom of the holder 911 so as to protrude in the axial direction of the holder 911. The tubular portion 912 is fixed to the second port 332 and communicates with the flow path 342 of the second port 332. The diameter of the tubular portion 912 is set smaller than the diameter of the holder 911.

The hollow needle 92 is located in the holder 911 and is formed on the bottom of the holder 911 so as to protrude in the axial direction of the holder 911. Further, the hollow needle 92 is disposed at a position corresponding to the tubular portion 912 and communicates with the flow path 342 of the second port 332 via the tubular portion 912. Further, a hole 921 is formed in the middle of the hollow needle 92, and the inside and outside of the hollow needle 92 communicate with each other through the hole 921. Thus, when the hollow needle 92 pierces the stopper 72 of the vial 7, the inside of the vial 7 and the flow path 342 of the second port 332 communicate with each other via the hollow needle 92.

In addition, it does not specifically limit as a constituent material of the connection instrument 9, For example, the thing similar to what was illustrated as a constituent material of the three-way cock 3 mentioned above can be used.

In the present embodiment, the connection device 9 is fixed to the second port 332. However, the present invention is not limited to this, and the connection device 9 is detachably attached to the second port 332 as in a third embodiment to be described later. You may be comprised so that.

The connecting portion 11 has a cylindrical shape, and a base end portion thereof is fixed to the third port 333 of the three-way stopcock 3. The constituent material of the connecting portion 11 is not particularly limited, and for example, the same materials as those exemplified as the constituent material of the three-way cock 3 described above can be used.

The proximal end of the tube 4 is fixed to the distal end of the connecting portion 11. That is, the tube 4 is connected to the third port 333 via the connecting portion 11 and communicates with the flow path 343 of the third port 333.

Further, a hollow puncture needle 5 having a sharp needle tip is connected to the distal end portion of the tube 4, and a cap 52 is detachably attached to the puncture needle 5. In addition, a pair of wings 51 a and 51 b are formed on the side of the proximal end side of the puncture needle 5. That is, the puncture needle 5 is a winged needle. Each of the wings 51a and 51b has flexibility and can be opened and closed by bending or bending the wings 51a and 51b.

When puncturing the puncture needle 5, the wings 51a and 51b are picked up with fingers and closed, and the puncture operation can be performed. It is also possible to puncture the other parts without picking the wings 51a and 51b. After puncturing the puncture needle 5, the wings 51a and 51b are opened, and the wings 51a and 51b are fixed to the skin with an adhesive tape or the like.

The length of the tube 4 is not particularly limited, but is preferably about 15 to 40 cm, and more preferably about 20 to 30 cm. Thereby, self-injection can be performed more easily.

The filter 8 is detachably attached to the first port 331 of the three-way stopcock 3, and the syringe 6 is detachably connected. That is, the filter 8 and the syringe 6 are selectively attached to the first port 331. In this case, the method of attaching the filter 8 and the syringe 6 to the first port 331 is not particularly limited, and examples thereof include fitting and screwing. In this embodiment, a screwing method is adopted. Yes.

The filter 8 has a housing 81 and a filter member 82 which is installed in the housing 81 and through which gas passes but bacteria do not pass.

The housing 81 includes a cylindrical portion 811 having a bottomed cylindrical shape, and a tubular portion 812 formed on the bottom portion of the cylindrical portion 811 so as to protrude in the axial direction of the cylindrical portion 811. The diameter of the tubular portion 812 is set smaller than the diameter of the tubular portion 811. In addition, an opening is formed in a portion corresponding to the tubular portion 812 at the bottom of the cylindrical portion 811. And the filter member 82 is being fixed to the bottom part of the cylindrical part 811 so that the said opening may be covered.

Further, on the inner peripheral surface of the tubular portion 812, a thread that is a screwing portion that is screwed with the protrusion 334 of the first port 331 of the three-way stopcock 3 is formed. The filter 8 is detachably attached to the first port 331 by screwing the screw thread into the protrusion 334.

The filter member 82 includes, for example, non-woven fabric and paper such as polypropylene, polysulfone, regenerated cellulose, polyamide, and polyester, or those obtained by applying a sealing process thereto.

The syringe 6 includes an outer cylinder 61, a gasket 66 that can slide within the outer cylinder 61, and a pusher 65 that moves the gasket 66 along the axial direction (longitudinal direction) of the outer cylinder 61. The gasket 66 is connected to the tip of the pusher 65.

The outer cylinder 61 is formed of a bottomed cylindrical member, and a mouth portion 62 whose diameter is reduced with respect to the body portion of the outer cylinder 61 is integrally formed at the tip portion thereof, that is, the center portion of the bottom portion on the tip side. Has been. From the mouth 62, a liquid such as a chemical solution is sucked or discharged. In addition, the first port 331 of the three-way cock 3 is detachably connected to the mouth portion 62.

A flange 64 is integrally formed on the outer periphery of the base end (rear end) of the outer cylinder 61.
Further, a scale indicating the liquid amount is attached to the outer peripheral surface of the outer cylinder 61.

The constituent material of the outer cylinder 61 is not particularly limited, and examples thereof include various resins such as polypropylene and cyclic polyolefin. In addition, it is preferable that the constituent material of the outer cylinder 61 is substantially transparent in order to ensure internal visibility.

In such an outer cylinder 61, a gasket 66 made of an elastic material is accommodated (inserted). A plurality (two in this embodiment) of ring-shaped protrusions are formed on the outer periphery of the gasket 66 over the entire periphery, and these protrusions are in close contact with the inner peripheral surface of the outer cylinder 61. By sliding, liquid-tightness can be more reliably maintained and slidability can be improved.

In addition, the gasket 66 has a hollow portion that opens to the base end surface. In this hollow portion, a head portion of a pusher 65 described later is screwed. A female screw is formed on the inner surface of the hollow portion of the gasket 66.

The constituent material of the gasket 66 is not particularly limited, and examples thereof include various rubber materials and various thermoplastic elastomers.

The pusher 65 has a rod-like main body 67 whose cross section is cross-shaped.
A head portion that is inserted into the hollow portion of the gasket 66 and connected to the gasket 66 is formed on the distal end side of the main body portion 67. On the outer periphery of the head portion, a male screw that can be screwed with a female screw on the inner surface of the hollow portion of the gasket 66 is formed. The gasket 66 and the pusher 65 are connected by screwing the male screw with the female screw. In addition, the gasket 66 and the pusher 65 are not limited to the connection by screwing, but may be, for example, a structure connected by uneven fitting, a structure fixed by adhesion, fusion, or the like, or an integrally molded structure. .

A disc-shaped flange 68 is formed on the base end side of the main body 67.
A lock adapter 63 is provided on the outer peripheral side of the mouth portion 62 of the outer cylinder 61. The lock adapter 63 has, on its inner peripheral surface, a thread that is a screwing portion that is screwed with the protrusion 334 of the first port 331 of the three-way cock 3. In the present embodiment, the lock adapter 63 is fixed to the distal end portion of the outer cylinder 61.

When connecting the syringe 6 to the first port 331, the mouth portion 62 of the syringe 6 is inserted into the first port 331, the syringe 6 (lock adapter 63) is rotated, and the protrusion 334 of the first port 331 is inserted. Then, the thread of the lock adapter 63 is screwed. Thus, the first port 331 and the mouth portion 62 of the syringe 6 are connected, and the protrusion 334 and the screw thread of the lock adapter 63 are screwed together, whereby the syringe 6 is held in the first port 331.

Further, a space (liquid storage space) surrounded by the outer cylinder 61 and the gasket 66 of the syringe 6 is filled with a liquid that dissolves or dilutes the medicine stored in the vial 7. The liquid is not particularly limited and may be appropriately selected depending on the drug. Examples thereof include water for injection, physiological saline, and glucose solution.

The liquid may be sealed in the syringe 6 in advance, or the liquid may be sucked into the syringe 6 when used.

In the present embodiment, the lock adapter 63 is fixed to the outer cylinder 61, but is not limited thereto, and for example, the lock adapter 63 moves along the axial direction of the outer cylinder 61 with respect to the mouth portion 62. It may be one that can be installed, one that can rotate about the axis (concentrically), one that can move along the axial direction, and one that can rotate about the axis.

Further, the constituent materials of the lock adapter 63 and the pusher 65 are not particularly limited, and for example, the same materials as those exemplified as the constituent material of the outer cylinder 61 described above can be used.

The vial 7 has a bottomed cylindrical rigid main body 71 in which a medicine is stored, and a stopper 72 that is provided in an upper mouth portion of the main body 71 and hermetically seals the space in the main body 71. ing. An annular member 73 is attached around the mouth of the main body 71 and the plug body 72, thereby preventing the plug body 72 from being detached from the main body 71. Further, the inside of the vial 7 has a negative pressure. The vial 7 is connected to the second port 332 through the connecting device 9 described above.

The drug is not particularly limited, and examples thereof include blood preparations such as dried human blood coagulation factor VIII, hormone preparations such as insulin preparations, and antiviral agents such as interferon preparations.

Also, the form of the drug is not particularly limited, and examples thereof include solids (tablets, granules, etc.), solids such as powders (powder, etc.), liquids (liquids, etc.) and the like.

The constituent material of the main body 71 is not particularly limited, and examples thereof include various glasses and various resins.

The plug body 72 can be pierced by the hollow needle 92 of the connection tool 9, and the constituent material thereof is not particularly limited. For example, various rubber materials and elastic materials such as various thermoplastic elastomers can be used. Can be mentioned.

Next, the use procedure (action) of the drug solution administration device 1 when performing self-injection will be described.
First, as shown in FIG. 1, the lever 38 of the three-way stopcock 3 is aligned with the position of the third port 333 so that the first port 331 and the second port 332 communicate with each other.

Next, as shown in FIG. 3, the vial 7 is connected to the connection device 9 with the filter 8 attached to the first port 331. At this time, the vial 7 is pushed into the holder 911 of the connection tool 9 from the stopper 72 side. As a result, the hollow needle 92 of the connection device 9 penetrates the stopper 72 of the vial 7, and the inside of the vial 7 and the second port 332 communicate with each other through the hollow needle 92. Since the inside of the vial 7 has a negative pressure, external air passes through the filter 8 and is introduced into the vial 7 through the three-way cock 3, and the inside of the vial 7 becomes atmospheric pressure. At this time, the filter 8 can prevent bacteria from entering the chemical liquid administration device 1 such as the three-way stopcock 3 or the vial 7.

Next, the filter 8 is removed from the first port 331 as shown in FIG. 4, and the mouth portion 62 of the syringe 6 is connected to the first port 331 as shown in FIG.

Next, as shown in FIG. 6, the pusher 65 is pressed and moved in the distal direction, the liquid sealed in the syringe 6 is introduced into the vial 7 from the syringe 6, and the vial 7 is shaken several times. Thereby, the medicine in the vial 7 is dissolved or diluted with the inflowing liquid, and the medicine liquid is stored in the vial 7.

Next, as shown in FIG. 7, the vertical direction of the vial 7 is reversed, the pusher 65 is pulled and moved in the proximal direction, and the drug solution in the vial 7 is sucked into the syringe 6 from the vial 7.

Next, as shown in FIG. 8, the lever 38 of the three-way cock 3 is aligned with the position of the second port 332, so that the first port 331 and the third port 333 communicate with each other.

Next, the cap 52 is removed from the puncture needle 5 and priming is performed.
Next, the tip of the puncture needle 5 is punctured at the target site, and the drug solution in the syringe 6 is administered. That is, the pusher 65 is moved while being pushed in the distal direction. Thereby, the chemical | medical solution in the syringe 6 is discharged | emitted from the syringe 6, flows out from the puncture needle 5 through the three-way cock 3 and the tube 4, and is administered.

Here, since the first port 331 to which the syringe 6 is connected and the third port 333 to which the tube 4 is connected via the connecting portion 11 are arranged on a straight line, air is not supplied during priming. It is difficult to remain, and resistance during administration of the drug solution is also reduced.

Further, since the second port 332 protrudes to the side of the first port 331 and the third port 333, a straight line connecting the first port 331 and the third port 333 is used as a central axis. The vial 7 can be rotated, so that it is possible to easily change the vertical direction of the vial 7 in the operation of inverting the vertical direction of the vial 7 as shown in FIG. 7 from the state shown in FIG. Can do.

As described above, according to the drug administration device 1, the drug in the vial 7 is dissolved or diluted to obtain a drug solution, and the drug solution is sucked into the syringe 6 and discharged from the puncture needle 5 with ease. Can be done quickly.

Further, in the above operation, an operation for inserting the puncture needle 5 into the stopper 72 of the vial 7 is unnecessary, and thus it is safe for the operator.

Second Embodiment
FIG. 9 is a perspective view showing the vicinity of the puncture needle of the drug solution administration device of the present invention (second embodiment), FIG. 10 is a schematic cross-sectional view of a connecting member in the drug solution administration device shown in FIG. FIG. 10 is a perspective view showing a separated state in the vicinity of the puncture needle of the drug solution administration device shown in FIG. 9. In the following, for convenience of explanation, the left side in FIGS. 9 to 11 is referred to as “front end” and the right side is referred to as “base end (rear end)”.

Hereinafter, the second embodiment of the drug solution administration device of the present invention will be described with reference to these drawings. However, the difference from the above-described embodiment will be mainly described, and description of similar matters will be omitted.

This embodiment is the same as the first embodiment except that the configuration near the puncture needle is different.

9 and 10, an easily breakable portion 57 is formed in the middle of the tube 4 in the vicinity of the puncture needle 5 of the drug solution administration device 1. Such an easily breakable portion 57 is configured to break more easily than the surroundings, specifically, the portions near the distal end side and the proximal end side.

By breaking such a breakable part 57, the medicinal solution administration device 1 can be divided into a first part 5a including the puncture needle 5 and a second part 5b on the base end side. Can be separated (see FIG. 11).

Trash including the puncture needle 5 must be properly treated as “needle trash” in accordance with various laws and regulations. Therefore, like this embodiment, it is only necessary to dispose only the first part 5a as needle dust by separating the first part 5a including the puncture needle 5 and the other second part 5b. The amount of needle dust is reduced. As a result, the economical efficiency at the time of discarding the chemical solution administration instrument 1 is improved. In other words, it is possible to reduce the frequency of dust removal as needle dust, and to suppress the cost for disposal. By breaking the easily breakable portion 57, the first portion 5a and the second portion 5b can be easily separated, so that there is no trouble in disposal and the operability is excellent.

Hereinafter, the easy break portion 57 will be described in detail.
As shown in FIGS. 9 and 10, the tube 4 includes a distal end side tube 54 whose distal end portion is connected to the puncture needle 5, and a proximal end side with respect to the distal end side tube 54, and the proximal end portion is a connecting portion 11. And a tubular connecting member 56 that connects the distal tube 54 and the proximal tube 55 to each other.

The connecting member 56 includes a distal end portion 561 connected to the distal end side tube 54, a proximal end portion 562 connected to the proximal end side tube 55, and an intermediate portion 563 that connects the distal end portion 561 and the proximal end portion 562. And have.

The tip 561 is formed with a pair of knobs 561a and 561b projecting on both sides thereof, and the base end 562 is formed with a pair of knobs 562a and 562b projecting on both sides thereof. Each of these knobs 561a, 561b, 562a, 562b has a flat plate shape. Also, each of the knobs 561a, 561b, 562a, 562b has a shape in which both surfaces thereof are recessed except for the edges so that the fingers can be easily hooked.

The intermediate portion 563 has a thin portion 563a that is thinner than the distal end portion 561 and the base end portion 562, and the thin portion 563a constitutes the easily breakable portion 57. Since the thin portion 563a is thinner than the distal end portion 561 and the base end portion 562, the thin portion 563a is more fragile than the distal end portion 561 and the base end portion 562, and breaks with a small force. Therefore, by constituting the easy break portion 57 with such a thin portion 563a, it is possible to form the easy break portion 57 that can reliably exhibit its function and has a simple structure.

Such a breakable portion 57 is, for example, gripping the distal end portion 561 with one hand and the proximal end portion 562 with the other hand, and at least one of the distal end portion 561 and the proximal end portion 562 with respect to the other. By twisting and rotating, it is broken so that it can be twisted. According to such a method, the easily breakable portion 57 can be easily broken. Hereinafter, for convenience of explanation, the above-described procedure is also referred to as a “rupture procedure”.

In particular, in this embodiment, a pair of knobs 561a and 561b are formed at the distal end portion 561, and a pair of knobs 562a and 562b are formed at the proximal end portion 562. By hooking a finger on these knobs 561a, 561b, 562a, 562b, the distal end portion 561 and the proximal end portion 562 are easily grasped, and the distal end portion 561 and the proximal end portion 562 are easily rotated. Therefore, the breaking procedure described above can be performed more easily and smoothly.

Further, it is preferable that the thin portion 563a (easy to break portion 57) has flexibility (flexibility), specifically, stretchability or stretchability. As a result, when the above-described breaking procedure is executed, the breakable easy portion 57 is deformed to be extended as the rotation angle between the distal end portion 561 and the proximal end portion 562 increases, and the rotation angle exceeds a predetermined angle. At that time, the stretching limit is exceeded and the breakable portion 57 is broken so that it can be twisted.

According to such a configuration, liquid tightness in the tube 4 can be ensured until immediately before the break, that is, in a state where the easily breakable portion 57 is being deformed. Therefore, for example, even if the easy breakable portion 57 is deformed unintentionally, if the easy breakable portion 57 is not broken, the liquid tightness in the tube 4 is ensured. Liquid leakage from the tube 4 can be prevented.

It should be noted that the predetermined angle is preferably 45 ° or more, and more preferably 90 ° or more. Thereby, since the easy-to-break part 57 does not break by some rotation, the unintentional break and the unintended break of the easy-to-break part 57 can be effectively prevented.

Further, the breakable portion 57 is preferably provided in the middle of the tube 4 and within a region within 10 cm from the proximal end of the puncture needle 5, and more preferably within a region within 3 to 6 cm. preferable. Thereby, the volume (bulk) of the 1st site | part 5a can be made smaller, and the generation amount of needle dust can be suppressed more. In particular, when the length is 3 to 6 cm, the above-described effects can be exhibited, and the easily breakable portion 57 can be appropriately separated from the puncture needle 5, so that the operability of the puncture needle 5 is not impaired.

The thin portion 563a (easy to break portion 57) is formed by forming a substantially V-shaped groove 563b on the outer periphery of the intermediate portion 563. Thereby, while being able to form the thin part 563a (easy to break part 57) easily, the groove | channel 563b becomes a mark and the user can visually recognize the easily breakable part 57 easily. Therefore, it becomes easy to perform the breaking procedure mentioned above, and operativity improves.

The groove 563b is formed so as not to penetrate the inside of the connecting member 56 (the lumen of the tube 4), thereby ensuring the liquid tightness of the tube 4. Further, the cross-sectional shape of the groove 563b is not limited to the V shape, and may be, for example, a substantially semicircle.

Such a groove 563b is preferably formed over the entire circumference of the intermediate portion 563. That is, it is preferable that the groove 563b has a ring shape. Thereby, the easy break portion 57 can be formed over the entire circumference of the intermediate portion 563. Therefore, the easy-to-break portion 57 has a configuration suitable for the act of twisting off by the above-described breaking procedure, and the breaking procedure can be performed easily and reliably.

The thickness of the thin portion 563a (easy to break portion 57) varies depending on the constituent material of the connecting member 56, but is about 0.2 to 1.0 mm at a portion corresponding to the bottom of the groove 563b. The thickness is preferably about 0.3 to 0.5 mm. As a result, the easily breakable portion 57 has an appropriate mechanical strength, and the easily breakable portion 57 is too fragile to cause unintentional breakage during use, or on the contrary, the easily breakable portion 57 is too strong and is large in breaking. It is possible to effectively prevent the need for force.

That is, by setting the thickness of the thin portion 563a to the above value, when there is no intention of breaking such as during use of the instrument, the breakage can be reliably prevented, and when there is an intention of breaking such as when discarding after use. Can constitute an easily breakable portion 57 that can be easily broken.

In addition, the front-end | tip part 561, the base end part 562, and the intermediate part 563 are integrally formed. Examples of these constituent materials, that is, constituent materials of the connecting member 56 include various resins such as polyvinyl chloride, polyethylene, polypropylene, and polyamide.

As the timing for breaking the breakable portion 57 having such a configuration, the puncture needle 5 is removed after completion of the administration of the drug solution, and then the breaking operation is performed. As described above, in the breaking operation, the distal end portion 561 is grasped with one hand and the proximal end portion 562 is grasped with the other hand, and at least one of the distal end portion 561 and the proximal end portion 562 is held with respect to the other. By rotating to twist, the breakable easy portion 57 positioned between them is twisted off. Thereby, as shown in FIG. 11, it isolate | separates into the 1st site | part 5a containing the puncture needle 5, and the other 2nd site | part 5b.
Then, only the separated first portion 5a can be disposed as needle dust.

<Third Embodiment>
FIGS. 12 and 13 are perspective views sequentially illustrating the operation (from the first state to the second state) of the multiway cock provided in the drug solution administration device (third embodiment) of the present invention, and FIG. FIG. 15 is a sectional view taken along line BB in FIG. In the following, for convenience of explanation, the upper side in FIGS. 14 and 15 is referred to as “upper” or “upper”, and the lower side is referred to as “lower” or “lower”.

Hereinafter, the third embodiment of the drug solution administration device of the present invention will be described with reference to these drawings, but the description will focus on the differences from the above-described embodiment, and description of similar matters will be omitted.

This embodiment is the same as the first embodiment except that the drug administration device further includes a release mechanism.

As shown in FIGS. 12 to 15, in the present embodiment, the connection tool 9 is detachably connected to the second port 332.

A cylindrical sealing member 39c made of an elastic material is disposed between the inner peripheral portion of the connection tool 9 and the outer peripheral portion of the second port 332. The sealing member 39c maintains liquid tightness when the connection tool 9 is connected to the second port 332. As a result, the liquid is prevented from leaking unintentionally when the liquid goes back and forth between the vial 7 and the three-way cock 3. The sealing member 39c is a method such as fitting, fusing (thermal fusing, high frequency fusing, ultrasonic fusing, etc.), adhesion (adhesion with an adhesive or a solvent), etc., to the second port 332. It is fixed by. In addition, the outer peripheral surface of the sealing member 39c has a tapered shape whose outer shape gradually decreases upward. In addition, the sealing member 39c may be fixed to the connection tool 9 side. In this case, the outer peripheral surface of the second port 332 has a tapered shape whose outer diameter gradually decreases upward.

And in the chemical | medical solution administration instrument 1, the state which can detach | leave from the 2nd port 332 of the connection tool 9 and the state which can detach | leave from the 2nd port 332 of the connection tool 9 are selected. For this purpose, a separation mechanism 30 is used. The detachment mechanism 30 prevents the connection tool 9 from being detached from the second port 332 in the first state, and enables the connection tool 9 to be detached from the second port 332 in the second state. It is configured.

Hereinafter, the separation mechanism 30 will be described.
As shown in FIGS. 12 to 15, the detachment mechanism 30 corresponds to a pair of projecting pieces 931 and 932 that project from the lower part of the outer peripheral portion of the tubular portion 912 of the connecting device 9 and a pair of projecting pieces 931 and 932. And a pair of engagement pieces 351 and 352 provided on the cock 35.

The protruding piece 931 and the protruding piece 932 protrude toward opposite sides (outside) through the central axis of the connecting device 9. The upper surfaces of the projecting pieces 931 and 932 are each curved in an arc shape like the outer peripheral portion of the cylindrical portion 32. Further, the lower surfaces of the projecting pieces 931 and 932 are flat surfaces.

On the other hand, the engagement piece 351 is provided on a side plate portion 362 provided at one end of the body portion 36, and the engagement piece 352 is a plate on the end portion on the opposite side of the lever 38 of the body portion 36 of the cock 35. The flange portion 361 is provided. The engagement piece 351 and the engagement piece 352 are arranged to face each other and project toward the second port 332 side (inner side). In addition, the engagement pieces 351 and 352 are curved in an arc shape like the protrusion pieces 931 and 932, respectively.

Then, when the cock 35 is turned, the engagement piece 351 moves on the circumference around the central axis of the cock body 36 in conjunction with the operation and engages with the protrusion 931. The engagement piece 352 can be in an engagement / disengagement state with respect to the protruding piece 932.

As shown in FIGS. 12 and 14, the engaging piece 351 can be engaged (contacted) with the protruding piece 931 from the upper side when the three-way cock 3 is in the first state. Similarly to the engaging piece 351, the engaging piece 352 can be engaged with the protruding piece 932 from above when the three-way cock 3 is in the first state. Such engagement can reliably prevent the connection tool 9 from being detached from the second port 332 (moving upward).

Further, the lower portion of the inner peripheral surface of the tubular portion 912 of the connection device 9 is pressed (closely contacted) with the lower portion of the outer peripheral surface forming the tapered shape of the sealing member 39c by the engagement. Thus, the liquid tightness between the connecting device 9 and the sealing member 39c is maintained. Note that, as described above, when the sealing member 39c is fixed to the connecting device 9 side, the inner peripheral surface of the tubular portion 912 of the connecting device 9 is in close contact with the outer peripheral surface of the second port 332.

As shown in FIGS. 13 and 15, when the lever 38 of the cock 35 is rotated 90 degrees clockwise toward the lever 38 and the three-way cock is in the second state, the engaging piece 351 becomes the protruding piece. The engagement piece 352 is also disengaged from the protrusion 932. By such separation, the engagement with each of the projecting pieces 931 and 932 is released, and thus the connecting device 9 can be reliably detached from the second port 332. And by this detachment | leave, the vial 7 can be removed from the three-way cock 3 together with the connection tool 9.

In the medicinal solution administration device 1, since the vial 7 in which the medicinal solution is sucked into the syringe 6 is not used in the operation after the suction operation, if it is removed from the three-way stopcock 3 as described above, the subsequent operation is obstructed. In addition, the drug solution administration operation can be easily performed.

As mentioned above, although the chemical | medical solution administration device of this invention was demonstrated based on embodiment of illustration, this invention is not limited to this, The structure of each part is substituted by the thing of the arbitrary structures which have the same function. can do. In addition, any other component may be added to the present invention.

Further, the drug solution administration device of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

In each of the above embodiments, a three-way cock is used as a multi-way cock. However, the present invention is not limited to this, and for example, a cock having four or more ports may be used.

The medicinal-solution administration device of the present invention has a first port, a second port, and a third port, and the first port, the second port, and the third port are selected from the first port, the second port, and the third port. A multi-way stopcock capable of taking a first state in which the first port and the second port communicate with each other and a second state in which the first port and the third port communicate with each other; A connecting device provided in the port, a first container containing a medicine connected to the second port via the connecting device, one end side connected to the third port, and a puncture on the other end side A tube to which a needle is connected; and a second container that is detachably connected to the first port, in which a liquid for dissolving or diluting the drug is enclosed, and capable of inhaling and discharging the liquid. And connecting the first container to the first port. After two containers are connected and the multiway cock is in the first state, the liquid is introduced from the second container into the first container, and the drug is dissolved or diluted to obtain a drug solution , Inhaling the medicinal solution from the first container into the second container, then setting the multi-way stopcock in the second state, discharging the medicinal solution from the second container, and passing the medicinal solution through the tube The puncture needle is configured to flow out. Therefore, it is possible to easily and quickly perform an operation of dissolving or diluting the drug to obtain a drug solution and causing the drug solution to flow out of the puncture needle. In addition, in the above operation, it is not necessary to pierce the puncture needle through the plug of the first container and the like, which is safe for the operator. Therefore, the chemical solution administration device has industrial applicability.

Claims (7)

1. A first port; a second port; and a third port. The first port, the second port, and the third port of the first port, the second port, and the third port. A multiway cock that can take a first state in which the first port communicates with the second port and a second state in which the first port communicates with the third port;
   A connecting device provided in the second port;
   A first container in which a medicine connected to the second port via the connection device is stored;
   A tube having one end connected to the third port and a puncture needle connected to the other end;
   A second container that is detachably connected to the first port, encloses a liquid that dissolves or dilutes the drug, and is capable of inhaling and discharging the liquid;
   The first container is connected to the connecting device, the second container is connected to the first port, and the liquid is discharged from the second container in a state where the multiway cock is in the first state. After being introduced into the first container and dissolving or diluting the drug to obtain a drug solution, the drug solution is inhaled from the first container into the second container,
   Next, the multi-way cock is in the second state, the chemical solution is discharged from the second container, and the chemical solution is configured to flow out of the puncture needle through the tube. Instruments.
2. A first port; a second port; and a third port. The first port, the second port, and the third port of the first port, the second port, and the third port. A multiway cock that can take a first state in which the first port communicates with the second port and a second state in which the first port communicates with the third port;
   A connecting device provided in the second port;
   A first container in which a medicine connected to the second port via the connection device is stored;
   A tube having one end connected to the third port and a puncture needle connected to the other end;
   A filter that is detachably attached to the first port and that allows gas to pass but bacteria not to pass through;
   A second container that is detachably connected to the first port, encloses a liquid that dissolves or dilutes the drug, and is capable of inhaling and discharging the liquid;
   With the multi-way stopcock in the first state, with the filter attached to the first port, connect the first container to the connection device,
   Then, removing the filter from the first port, connecting the second container to the first port,
   Next, after introducing the liquid from the second container into the first container and dissolving or diluting the drug to obtain a drug solution, the drug solution is inhaled from the first container into the second container,
   Next, the multi-way cock is in the second state, the chemical solution is discharged from the second container, and the chemical solution is configured to flow out of the puncture needle through the tube. Instruments.
3. The filter has a housing that is detachably attached to the first port, and a filter member that is installed in the housing and through which gas passes but bacteria do not pass,
   The inside of the first container has a negative pressure, and when the first container is connected to the second port via the connecting device, the air that has passed through the filter is introduced into the first container. The medicinal-solution administration device according to claim 2 configured to be configured as described above.
4. 3. The chemical solution according to claim 1, wherein the first port and the third port are arranged on a straight line, and the second port protrudes toward a side of the first port. Dosing device.
5. 3. The drug solution administration device according to claim 1, wherein the puncture needle is a winged needle.
6. In the middle of the tube, provided in the vicinity of the puncture needle, further comprising a breakable portion that breaks more easily than the surrounding portion,
   The medicinal solution administration according to claim 1 or 2, wherein the easy-to-break portion is broken so that it can be separated into a first portion including the puncture needle and a second portion other than the first portion. Instruments.
7. The multi-way stopcock has a cylindrical shape, and a cylindrical portion in which the first port, the second port, and the third port are arranged on an outer peripheral portion thereof, and is rotatable in the cylindrical portion. A cock having a cylindrical body portion that is inserted and formed with flow paths corresponding to the first port, the second port, and the third port, respectively, and rotating the cock Can take the first state and the second state,
   The detachment mechanism further prevents the detachment of the connection tool from the second port in the first state and enables the connection tool to be detached from the second port in the second state. Or the chemical | medical solution administration device of 2.

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