JP2009056176A - Medical solution infusion device and system - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a medical solution infusion device and system favorably responding to a case where an infusion pathway of the medical solution to a subject is not normally secured, and preventing the leakage of the medical solution when an operator tries to secure the infusion pathway again. <P>SOLUTION: This medical solution infusion device is provided with a piston drive mechanism 130 for extractably/retractably moving a piston 220 relative to a cylinder member, and a load cell 138 for detecting the pressure of the medical solution in a syringe. When the pressure of the medical solution detected by the load cell 138 exceeds a predetermined upper limit, the piston drive mechanism 130 stops the operation of extracting the piston. After that, the piston drive means 130 pulls back the piston 220 within a range of preventing the inside of the syringe from getting a negative pressure. This constitution can reduce the pressure of the medical solution in the syringe 200 and a tube T to prevent the leakage of the medical solution even if an operator turns a knob of a stopcock. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a chemical liquid injector and a chemical liquid injection system that push a chemical liquid in a syringe toward a subject by pushing a piston of the syringe. In particular, even when the injection route of the chemical solution to the subject is not normally secured, it can be suitably handled, and the chemical solution is prevented from leaking when the operator re-establishes the injection route. The present invention relates to a chemical injection device and a chemical injection system that can be used.

Medical fluoroscopic imaging devices include CT (Computed Tomography) scanners, MRI (Magnetic Resonance Imaging) devices, and PET (Positron).
Emission Tomography) device, ultrasonic diagnostic device, CT angiography device, MR angiography device and the like. When such a device is used, for example, a contrast medium or physiological saline (hereinafter also simply referred to as “medical solution”) may be injected into the patient's body for the purpose of obtaining a clear image. .

  Syringes used for injecting medicinal solutions are called prefilled types in which the medicinal solution is initially filled in the syringes, and suction types in which a predetermined amount of medicinal solution is sucked into the syringe from a medicinal solution tank containing the medicinal solution. There is a thing.

  Patent Document 1 discloses a chemical liquid injector using a suction type syringe. In this example, the tube connected to the syringe is branched into two on the way, one of the branched tubes is an infusion tube connected to the patient, and the other is an aspiration tube connected to the drug solution tank.

  For example, a three-way cock can be used at the branch portion. According to such a configuration, the operator can switch between a state where the chemical liquid can be sucked from the chemical liquid tank into the syringe and a state where the chemical liquid can be injected from the syringe into the subject by operating the stopcock knob. Since it is not necessary to replace the tube when the chemical solution is sucked and when the chemical solution is injected, the operation can be simplified. On the other hand, in order to inject a chemical into a subject, it is necessary for the operator to switch to a state where the operator can inject the chemical from the syringe into the subject by operating the stopcock knob after sucking the chemical from the chemical tank into the syringe. If the operator forgets this operation, or if the knob is not sufficiently moved due to an erroneous operation, the chemical solution injection path is not normally secured.

In order to determine whether or not the chemical solution injection path is normally secured, for example, whether or not the pressing force applied to the piston of the syringe (corresponding to the pressure of the chemical solution in the syringe) is within a predetermined range. What is necessary is just to investigate (for example, refer patent document 2). When the pressing force exceeds a predetermined range, it is determined that the injection path is not normally secured, and the piston drive mechanism of the chemical liquid injector is stopped, so that the chemical liquid injection can be interrupted.
JP 2004-65737 A WO2005 / 039675A1

  According to the configuration described above, the piston drive mechanism is stopped when the chemical injection path is not normally secured, so that an excessive load is applied to the piston drive mechanism, and the pressure in the syringe and the tube is reduced. An abnormal rise is prevented.

When the piston drive mechanism stops, the operator may, for example, once remove the needle from the subject and re-stab the needle so as to correctly pierce the blood vessel in order to ensure the injection path normally.
However, when the piston drive mechanism is stopped, the pressure of the chemical liquid is increased. Therefore, if the operator pulls out the needle from the subject and then moves the stopcock knob to the open position, the chemical liquid in the tube is removed from the needle tip. There was a possibility of leakage.

  The present invention has been made in view of the above problems, and the purpose thereof can be suitably dealt with even when the injection route of the chemical liquid to the subject is not normally secured, and the operator can It is an object of the present invention to provide a chemical solution injection device and a chemical solution injection system that can prevent the chemical solution from leaking out when the injection path is secured again.

In order to achieve the above object, a chemical liquid injector of the present invention is a chemical liquid injector that holds a syringe having a cylinder member and a piston slidably inserted therein and pushes the chemical liquid in the syringe toward a subject. ,
Piston driving means for moving the piston forward and backward with respect to the cylinder member;
Fluid pressure detecting means for detecting the pressure of the chemical liquid in the syringe while the piston driving means presses the piston toward the cylinder member;
With
The piston drive means is
When the pressure of the chemical liquid detected by the hydraulic pressure detection means exceeds a predetermined upper limit value, the operation of advancing the piston is stopped,
Thereafter, the piston is pulled back.
In addition, it is preferable that the distance which pulls back a piston is the range in which the inside of the said syringe does not become a negative pressure.

  According to the chemical solution injection device of the present invention, for example, when the injection is started in a state where the injection route to the subject is not normally secured, the pressure of the chemical solution detected by the hydraulic pressure detection means has a predetermined upper limit value. When it exceeds, the operation to advance the piston is stopped. In this state, the pressure of the chemical solution in the cylinder or the tube connected to the cylinder is increased. However, in this device, the piston is then pulled back, so that the chemical solution in the syringe and the tube is removed. Therefore, even if the operator pulls out the needle from the subject, the liquid medicine does not leak from the needle tip. In addition, the pulling back operation of the piston is performed within a range in which the inside of the syringe does not become a negative pressure, so that the chemical liquid does not flow back into the syringe.

In the chemical injection device of the present invention, the pressure of the chemical liquid is detected by the hydraulic pressure detection means while the piston driving means pulls back the piston.
On the basis of the detection result, when it is determined that the pressure of the chemical liquid in the syringe has decreased to a predetermined value, the piston retracting operation by the piston driving means may be stopped.

  In the chemical injection device according to the present invention, the magnitude of the reaction force from the piston is detected by the pressure sensor while the piston drive means pulls back the piston, and the reaction force becomes zero when the reaction force becomes zero. The pulling back operation by the driving means may be stopped.

  A chemical solution injection system according to the present invention includes the chemical solution injection device according to the present invention, and a controller with a display connected to the chemical solution injection device, which is capable of displaying a state of chemical solution injection. And when the chemical | medical solution injection | pouring operation | movement by the said piston drive means is stopped based on the detection result of the said hydraulic pressure detection means, it becomes the structure by which the alarm to the effect that the injection | pouring operation | movement was stopped is displayed on the said display.

  As described above, according to the present invention, even when the injection route of the chemical liquid to the subject is not normally secured, it can be suitably dealt with, and the operator re-secures the injection route. It is possible to provide a chemical solution injection device and a chemical solution injection system that can prevent the chemical solution from leaking out.

(First embodiment)
Hereinafter, an embodiment of the present invention will be described with reference to the drawings. FIG. 1 is a perspective view showing an example of a chemical liquid injector of the present invention. In addition, the chemical | medical solution injection | pouring system provided with the chemical | medical solution injection | pouring apparatus and the display is demonstrated in 2nd Embodiment.

  As shown in FIG. 1, the drug solution injector 110 of the present embodiment has an elongated shape as a whole, and a concave portion 114 to which the syringe 200 is attached is provided on the front side of the upper surface. The recess 114 corresponds to the shape of the syringe 200 and is formed in a semi-cylindrical shape. The recess 114 extends in the length direction of the device 110 and is formed over approximately half the length of the entire device 110.

The syringe 200 is a conventional one, and includes a cylindrical cylinder member 210 and a piston 220 that is slidably inserted therein. A conduit portion 215 to which a tube (not shown) is connected is formed at the tip (upper side in the drawing) of the cylinder member 210. A flange portion 211 is formed at the rear end of the cylinder member 210.
A gasket 223 (see FIG. 2) is provided at the front end of the piston 220, and the rear end is a disc-shaped flange portion 221. The back surface of the flange portion 221 is a flat surface.

  As shown in FIG. 1, holding members 122 and 122 for holding a flange portion 211 (detailed below) of the syringe 200 are provided at substantially the center of the concave portion 114 in the length direction. The holding members 122 and 122 are a pair of members that hold the flange portion 211 from both sides, and have arc-shaped grooves into which the flange portion 211 of the cylinder member 210 is inserted.

  A piston drive mechanism 130 that slides the piston 220 is disposed near the rear end of the recess 114.

  As shown in FIG. 2, the piston drive mechanism 130 is attached to a screw shaft 137 that rotates using a motor (not shown) as a drive source, and the front side (left side in the drawing) of the screw shaft 137, and according to the rotation of the screw shaft 137. A substantially cylindrical holder member 135 that reciprocates in a direction along the shaft.

  The holder member 135 has a pressing member 132 that contacts the back surface of the flange portion 221 of the piston 220. The pressing member 132 has a shape such that a flat cylinder is turned sideways, and has a flat pressing surface 132a for pressing the back surface of the flange portion 221 of the piston. Claw portions 133 and 133 extend from the left and right sides of the outer periphery of the pressing member 132 toward the flange portion 221 (forward). The claw portion 133 is locked to the left and right ends of the flange portion 221 of the piston.

  In the example of FIG. 1, by moving the entire syringe 200 downward, the syringe 200 is set in the recess 114, and the flange 211 of the cylinder member 210 is fitted in the groove of the holding member 122. As a result, the axial and radial positions of the cylinder member 210 are fixed.

  Refer to FIG. 2 again. From the back side of the pressing member 132 of the piston drive mechanism 130, an elongated cylindrical portion 131 extends rearward (right side in the figure). Inside the cylindrical portion 131, a ball screw nut (not shown) to which the screw shaft 137 is screwed is attached. The screw shaft 137 receives power from a drive source (not shown) such as a motor and rotates forward and backward on the spot. When the screw shaft 137 is rotated a predetermined number of times, the holder member 135 moves in the front-rear direction (the left-right direction in the drawing) by a distance corresponding to the rotation.

  A load cell (pressure sensor) 138 for detecting the magnitude of the pressing force (reaction force from the piston 220) applied to the piston 220 is attached to the pressing surface 132a of the pressing member 132. In FIG. 2, the load cell 138 is drawn so as to bite into the pressing member 132, but the load cell 138 may be arranged on the surface of the pressing surface 132a.

  Although illustration is omitted, the chemical injection device 110 has a built-in control means for controlling the operation of the piston drive mechanism 130. When the control means operates a drive source (motor or the like) according to a predetermined control program, the piston 220 is moved by a predetermined distance at a predetermined speed. The control unit also controls the operation of the piston drive mechanism 130 based on the detection result of the load cell 138.

FIG. 3 shows a state in which the stopcock-equipped tube T is connected to the conduit portion 215 of the syringe.
This stopcock-equipped tube T has a three-way stopcock 78. A path that branches from the three-way stopcock 78 to the left in the figure is constituted by an injection tube 73a for injecting a drug solution to a subject. An indwelling needle 74 is attached to the tip of the tube 73a. A path that branches from the three-way cock 78 upward in the figure is constituted by a suction tube 73b for sucking a chemical liquid contained in a chemical liquid tank (not shown) into the syringe.

  The three-way stopcock 78 has a flat knob 79 that an operator can pinch and turn with a finger. In the example of FIG. 3, an indicator 79 a (for example, an “OFF” character stamped) is attached to one end of the knob 79.

As shown in FIG. 3, when the knob 79 is turned so that the indicator 79a is on the side of the injection tube 73a, the chemical solution can be sucked from the chemical solution tank into the syringe. On the other hand, as shown in FIG. 6, when the knob 79 is turned so that the indicator 79 a is on the suction tube 73 b side, the medical solution can be injected from the syringe to the subject.
However, as shown in FIGS. 4 and 5, when the indicator 79 a of the knob 79 faces the intermediate position between the injection tube 73 a side and the suction tube 73 b side, any route remains closed.

  Next, the operation of the chemical liquid injector of the present embodiment configured as described above will be described with reference to FIGS. 3 to 6 respectively show the suction of the chemical liquid from the chemical liquid tank into the syringe, the piston pressing operation for injecting the chemical liquid, the piston retracting operation, and the piston pressing operation again.

  First, after an empty syringe is set in the chemical solution injector, the chemical solution is sucked from the chemical solution tank into the syringe as shown in FIG. In the state of FIG. 3, the indwelling needle 74 at the tip of the injection tube 73a is inserted into the subject's arm or the like (not shown), and the tip of the suction tube 73b is connected to a chemical solution tank (not shown). The knob 79 of the three-way stopcock 78 is at a position where the indicator 79a faces the injection tube 73a side, so that the chemical liquid can be sucked from the chemical liquid tank into the syringe.

  In this state, the driving source of the piston driving mechanism 130 is driven to retract the pressing member 132, and the piston 220 connected to the pressing member 132 is pulled by a predetermined distance. Thereby, the inside of the syringe 200 becomes negative pressure, and the chemical solution in the chemical solution tank is sucked into the syringe 200 through the tube T with stopcock.

  When a predetermined amount of the chemical solution in the syringe 200 is sucked in this way and the operation of the piston driving means stops, the operator then turns the stopcock knob 79 to the suction tube 73b side so that the chemical solution can be injected from the syringe to the subject. To do. Here, FIG. 4 shows a state in which the stopcock knob 79 is not sufficiently turned. In the state of FIG. 4, the knob 79 is at a position where the indicator 79 a faces an intermediate position between the injection tube 73 a side and the suction tube 73 b side. In this state, the chemical cannot be injected from the syringe into the subject.

  In this state, when the operator presses a predetermined start button to start driving the piston drive mechanism 130 so as to start the chemical injection, the pressing member 132 is advanced and the piston 220 is pressed toward the cylinder member 200 side. (See arrow A). While the piston driving mechanism 130 is being driven, a pressing force (reaction force from the piston) applied to the piston 220 by the load cell 138 is detected. In this example, the detection of the pressing force by the load cell 138 is performed at predetermined time intervals. By looking at the detection result of the load cell 138, the pressure of the chemical solution in the syringe can be indirectly known. In the state of FIG. 4, since the stopcock 78 is closed, the piston 220 is hardly pushed into the syringe 210, and as the piston drive mechanism 130 continues to be driven (that is, as the push member 132 is advanced), the pusher 78 is pushed. Pressure increases.

  Thereafter, when the detection result of the load cell 138 exceeds a predetermined upper limit value, the driving of the piston drive mechanism 130 is stopped.

  That the detection result of the load cell exceeds a predetermined upper limit means that the pressure of the chemical solution in the syringe has reached a predetermined value. Thus, according to the configuration of the present embodiment, the operation of the piston drive mechanism is stopped when there is a possibility that the injection path is not normally secured, thereby preventing an excessive load from being applied to the piston drive mechanism. can do. Moreover, it can prevent that the pressure of the chemical | medical solution in a syringe or a tube becomes high too much, and a syringe, a tube, etc. are damaged, or the connection part etc. which connect a stopcock and a tube disconnect.

  By the way, when the driving of the piston driving mechanism 130 is stopped as described above, the piston 220 remains pressed toward the cylinder member 210, so that the pressure of the chemical solution in the syringe and the tube increases. is doing. Therefore, in this state, if the indwelling needle 74 is removed from the subject and the stopcock knob 79 is turned to the suction tube 73b side (a state in which a medical solution can be injected from the syringe into the subject), the indwelling needle 74 removes the chemical solution. May leak.

  Therefore, in the apparatus of the present embodiment, in order to prevent this, after stopping the driving of the piston driving mechanism 130, as shown in FIG. Is pulled back by the distance (arrow B direction).

  The “predetermined distance” to be pulled back at this time may be set within a range in which the inside of the syringe 200 does not become negative pressure. Specifically, the piston 220 may be pulled back by a preset distance.

  Alternatively, the reaction force from the piston 220 is detected by the load cell 138 even during the pulling operation, and the pulling operation is stopped when the detection result falls within a predetermined range (for example, when it becomes almost zero). You may make it do.

  By pulling back the piston 220 by a predetermined distance as described above, the pressure of the chemical solution in the syringe 200 and the tube T decreases. Therefore, even if the operator subsequently turns the stopcock knob 79 to inject the drug solution from the syringe to the subject as shown in FIG. 6, the drug solution does not leak from the indwelling needle 74.

  Next, the operator normally secures the path of the drug solution from the syringe to the subject by re-piercing the blood vessel with the needle. Then, when the operator presses a predetermined start button (one example) on the chemical solution injector 110, the piston driving means 130 is driven as shown in FIG. 6, and the injection of the chemical solution is started. In the state of FIG. 6, the stopcock knob 79 is rotated to a predetermined position, so that the drug solution in the syringe is injected into the subject through the tube T without any trouble.

  Thereafter, the driving of the piston driving means is stopped by a conventionally known method, and the injection of a predetermined amount of the chemical liquid from the syringe to the subject is completed.

  According to the chemical solution injector of the present embodiment as described above, even if an injection is started in a state where the injection path is not normally secured as shown in FIG. 4, the detection result of the load cell 138 is a predetermined value. The operation of the piston drive mechanism 130 is stopped when the upper limit value is exceeded. In this state, since the pressure of the chemical solution in the syringe 200 and the tube T is increased, the chemical solution may leak if the indwelling needle 74 is removed from the subject. However, as shown in FIG. 5, after the operation of the piston drive mechanism 130 is stopped, the piston is pulled slightly, so that the pressure of the liquid medicine in the syringe and the tube decreases, and the needle is removed from the subject. Even if it is removed, the chemical will not leak.

As mentioned above, although one form of this invention was demonstrated, the chemical injection device of this invention can be variously changed besides said structure.
(Second Embodiment)
FIG. 7 is a perspective view showing a chemical injection system including a chemical injection device and a display. This chemical solution injection system 100 includes a chemical solution injection device 110 and a controller 101 with a display connected to the device via a cable 102. The chemical liquid injector 110 shown in the figure can be equipped with two syringes. Thus, the chemical injection device of the present invention may be capable of mounting a plurality of syringes.

  Also in the chemical liquid injection system 100 of FIG. 7, as in the first embodiment, the reaction force from the piston is detected by the load cell while the piston drive mechanism is operated to inject the chemical liquid. Then, when the load cell detection result exceeds a predetermined upper limit value, the operation of the piston drive mechanism is stopped. Thereafter, the chemical liquid is prevented from leaking from the needle tip by slightly pulling the piston.

  On the display 104 of the controller 101, the injection status (for example, the pressure and injection speed of the chemical solution and the remaining amount of the chemical solution in the syringe) during the chemical injection can be displayed in real time. Further, when the operation of the piston drive mechanism is stopped based on the detection result of the load cell (see FIG. 4), an alarm indicating that the injection operation is stopped is displayed as shown in the screen 104 of FIG. Also good. In particular, whether or not the chemical solution injection path is accurately secured and an alarm for resetting the injection path may be displayed.

  Although an example of the present invention has been described above, the present invention is not limited to the specific configuration described above. For example, with regard to the configuration of the syringe, only the gasket is inserted into the cylinder member, and a predetermined connecting member provided in the chemical injection device is connected to the back surface of the gasket to move the gasket forward and backward (rodless type, It is also possible to use a chemical liquid injector that handles a syringe of a front loading type (see, for example, US Pat. No. 4,677,980 and US Pat. No. 6,659,127).

  Moreover, it may replace with a load cell and may utilize the hydraulic pressure detection means which detects the magnitude | size of the pressure of the chemical | medical solution in a syringe more directly. For example, a gasket that is relatively easy to deform when subjected to a reaction force from a chemical solution (the inner surface is in contact with the chemical solution and a piston rod is connected to the outer surface), and is pressed by the gasket when the gasket is deformed. A sensor structure having a rod-shaped member that is moved may be used. When the pressure of the chemical solution in the syringe is high, the gasket is greatly deformed, and the rod-shaped member is pushed out for a longer distance. By detecting the amount of movement of the gasket, the pressure of the chemical solution can be known more directly.

It is a perspective view which shows an example of the chemical injection device of this invention. It is a cross-sectional view which shows the structure of the chemical injection device of FIG. It is a top view for demonstrating operation | movement of a chemical injection device (initial state). It is a top view for demonstrating operation | movement of a chemical injection device (chemical injection). It is a top view for demonstrating operation | movement of a chemical injection device (injection stop). It is a top view for demonstrating operation | movement of a chemical injection device (chemical injection). It is a perspective view which shows an example of a chemical injection system. It is a figure which shows an example of the alarm displayed on a display.

Explanation of symbols

78 Three-way stopcock 79 Knob 79a Indicator 100 Chemical solution injection system 110 Chemical solution injection device 114 Recess 122 Holding member 130 Piston drive mechanism 132 Press member 132a Press surface 133 Claw portion 135 Holder member 137 Screw shaft 138 Load cell 200 Syringe 210 Cylinder member 211 Flange portion 215 Conduit portion 220 Piston 221 Flange portion 223 Gasket

Claims (7)

A chemical liquid injector that holds a syringe having a cylinder member and a piston slidably inserted therein and pushes the chemical liquid in the syringe toward a subject,
Piston driving means for moving the piston forward and backward with respect to the cylinder member;
Fluid pressure detecting means for detecting the pressure of the chemical liquid in the syringe while the piston driving means presses the piston toward the cylinder member;
With
The piston drive means is
When the pressure of the chemical liquid detected by the hydraulic pressure detection means exceeds a predetermined upper limit value, the operation of advancing the piston is stopped,
Then, the chemical | medical solution injection | pouring apparatus characterized by pulling back the said piston. While the piston drive means pulls back the piston, the liquid pressure detection means detects the pressure of the chemical liquid,
2. The chemical solution injection according to claim 1, wherein when the pressure of the chemical solution in the syringe is determined to have decreased to a predetermined value based on the detection result, the pulling back operation of the piston by the piston driving unit is stopped. apparatus.   The chemical liquid injection device according to claim 1 or 2, wherein the liquid pressure detection means is a pressure sensor that detects a magnitude of a reaction force from the piston. The piston driving means has a pressing member that presses the back surface of the flange portion at the rear end of the piston,
The said pressure sensor is a chemical | medical solution injection apparatus of Claim 3 arrange | positioned between the back surface of the said flange part, and the said press member.   While the piston driving means pulls back the piston, the pressure sensor detects the magnitude of the reaction force from the piston, and when the reaction force becomes zero, the pulling operation by the piston driving means is stopped. Item 5. A chemical injection device according to Item 3 or 4.   The chemical injection device according to any one of claims 1 to 5, wherein a tube with a three-way cock is connected to the syringe, one of which is branched to a chemical tank and the other is connected to an indwelling needle. The chemical injection device according to any one of claims 1 to 6,
A controller with a display connected to the display and capable of displaying the injection state of the chemical solution,
A chemical liquid injection system in which an alarm indicating that the injection operation is stopped is displayed on the display when the chemical liquid injection operation by the piston driving unit is stopped based on a detection result of the liquid pressure detection unit.

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