JP2014510575A - Monitoring of power injector operations via motor current measurement - Google Patents

Monitoring of power injector operations via motor current measurement Download PDF

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Publication number
JP2014510575A
JP2014510575A JP2013554480A JP2013554480A JP2014510575A JP 2014510575 A JP2014510575 A JP 2014510575A JP 2013554480 A JP2013554480 A JP 2013554480A JP 2013554480 A JP2013554480 A JP 2013554480A JP 2014510575 A JP2014510575 A JP 2014510575A
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Prior art keywords
syringe
ram
injector
movement
information set
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JP2013554480A
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Japanese (ja)
Inventor
エル.ウィン チャルーズ
エム.スチェッキ トッド
トゥーヒド カーン モード
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アシスト・メディカル・システムズ,インコーポレイテッド
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Priority to US201161443030P priority Critical
Priority to US61/443,030 priority
Priority to US13/115,719 priority patent/US20120204997A1/en
Priority to US13/115,719 priority
Application filed by アシスト・メディカル・システムズ,インコーポレイテッド filed Critical アシスト・メディカル・システムズ,インコーポレイテッド
Priority to PCT/US2012/024216 priority patent/WO2012112347A1/en
Publication of JP2014510575A publication Critical patent/JP2014510575A/en
Application status is Pending legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546Front-loading type injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3114Filling or refilling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/14Detection of the presence or absence of a tube, a connector or a container in an apparatus

Abstract

  Embodiments of the present invention monitor resistance to ram movement and detect one or more injector work conditions based on the resistance. Some embodiments automatically detect whether a syringe is present in each syringe chamber of the injector based on ram motion resistance, so that subsequent steps in the injection process are based on the presence or absence of the syringe. It can be started or delayed automatically. Other injector work situations that can be detected are: syringe syringe sleeve misaligned during operation, syringe wiper misaligned inside syringe barrel, syringe internal occlusion, and injection Including overpressure inside. The preferred method of measuring the resistance of ram movement is to measure how much current is required by the motor driving the ram.

Description

  This specification generally relates to the operation of medical fluid injection systems.

  In many medical environments, medical fluid is infused into a patient during diagnosis or treatment. One example is injecting a contrast agent into a patient to improve computed tomography (CT), angiography, magnetic resonance (MR), or ultrasound imaging using a powered fluid injection system.

  The contrast agent is typically injected into the catheter by an automatic injection system. Although contrast injection devices vary widely, most systems include a syringe operatively connected to a catheter. The injector includes a syringe chamber that houses a syringe. The syringe is typically reusable several times. The injector also includes a ram capable of reciprocating within the syringe chamber. When the ram is moved to create a partial vacuum inside the syringe, the contrast agent is aspirated into the syringe. Reversing the direction of the ram first ejects air from the syringe and then delivers the contrast agent to the catheter at a rate and volume determined by the rate of motion of the ram.

  In addition, such treatment may include the injection of fluids other than contrast agents. For example, a saline wash and / or fluid drug infusion may be desired. Thus, the injector can include a plurality of syringe chambers for receiving a plurality of syringes. In this case, the injector has a ram for each syringe chamber. These additional syringe chambers and rams can function in the same manner as described above, with one difference being that fluids other than contrast agents are aspirated into and delivered from each syringe. It is to be done. Housing multiple syringes with a single injector is taught by US patent application Ser. No. 12 / 094,009 (US Publication No. 2009/0149743) entitled Medical Fluid Injection System. (Same assignee as the present application, incorporated herein by reference in its entirety).

  The process of filling the syringe with medical fluid and injecting the medical fluid can be automated as much as possible to reduce the time associated with the injector setup and / or minimize operator error. preferable. Increasing setup speed is particularly important in CT applications. One step that generally causes operator error is loading the syringe into the appropriate syringe chamber. In some cases, the operator loads the syringe into the wrong syringe chamber (eg, in procedures where fewer than the total number of syringe chambers are utilized). In some cases, the operator attempts to load the syringe into the appropriate syringe chamber, but inadvertently misaligns the syringe, leaving it unsuitable for subsequent processing. In some cases, the operator simply forgets to load the syringe, paying attention to other preparatory work on the patient for the procedure. A problem arises when the automatic injection process begins with the syringe not properly loaded into the syringe chamber.

  Embodiments of the present invention monitor the resistance of the injector to ram movement and detect one or more working conditions of the injector based on the resistance. Some embodiments automatically detect whether a syringe is present in one or more syringe chambers of the injector based on ram motion resistance, so that subsequent steps in the syringe filling process It can be started or delayed automatically based on the presence or absence of the syringe. Other injector work situations that can be detected are: syringe syringe sleeve misaligned during operation, syringe wiper misaligned inside syringe barrel, syringe internal occlusion, and injection Including overpressure inside. The preferred method of measuring the resistance of ram movement is to measure how much current is required by the motor driving the ram.

  In embodiments that use ram motion resistance to detect the presence of a syringe, the ram of the syringe can be advanced into the respective syringe chamber of the syringe (e.g., as is typically done during the syringe filling process), and The presence or absence of the syringe can be determined based on how much the movement is resisted. If such movement is resisted by a substantial amount (eg, above a threshold), it can be concluded that the syringe wiper is interfering with the movement and thus the syringe is present. If such movement is resisted by a smaller amount, it can be concluded that the syringe wiper is not interfering with the movement and thus no syringe is present.

  Embodiments of the invention can provide one or more of several advantages. For example, some such systems may be advantageous compared to systems that use optical or mechanical sensors to detect the presence of a syringe. In such a system, medical fluids (especially contrast agents) may stick to the device in a state that interferes with the sensor operation, thereby impairing the reliability of the sensor. In contrast, embodiments of the present invention can detect the presence of a syringe based on parameters that can be measured or repeated very easily. An important advantage provided by many embodiments of the present invention is improved efficiency and time savings. By detecting many of the aforementioned injector work conditions rather than those described below, a considerable amount of time wasted can be avoided. Furthermore, enhancing the automation of such procedures allows the operator to perform various processes in parallel rather than sequentially. Such time savings are particularly important in environments (eg CT) where the operator must adhere to a strict schedule for completing the treatment within a certain time. Some embodiments of the invention involve monitoring the status of the infusion operation (eg, monitoring a misaligned syringe sleeve) to avoid damage to the injector itself. Some embodiments involve monitoring the injector work status (monitoring overpressure conditions during infusion) to increase patient safety. These and / or other advantages can be provided by embodiments of the present invention.

  The following drawings show specific embodiments of the invention and therefore do not limit the scope of the invention. The drawings are not to scale (unless otherwise noted) and are intended to be used in connection with the description in the detailed description below. Embodiments of the invention are described below in connection with the accompanying drawings. Like numbers indicate like elements.

FIG. 1 is a perspective view of an example injector according to an embodiment of the present invention. FIG. 2A is a perspective view of the syringe / plunger assembly of the example injector of FIG. 1 with the syringe present in one of the syringe / plunger assemblies. 2B is a perspective view of the syringe / plunger assembly of the example injector of FIG. 1 with no syringe present in one of the syringe / plunger assemblies. FIG. 3A is a schematic diagram illustrating an example syringe / plunger assembly according to an embodiment of the present invention in the presence of a syringe. FIG. 3B is a schematic diagram illustrating the example syringe / plunger assembly of FIG. 3A in the absence of a syringe. FIG. 4 is a schematic diagram illustrating an example syringe / plunger assembly according to an embodiment of the present invention in the absence of a syringe. FIG. 5 is a block diagram illustrating an example injection system according to an embodiment of the present invention. FIG. 6 is a flowchart illustrating an example method according to an embodiment of the present invention.

  The following detailed description is exemplary in nature and is in no way intended to limit the scope, applicability, or configuration of the invention. Moreover, the following description provides a practical example for implementing exemplary embodiments of the present invention. Examples of configurations, materials, dimensions, and manufacturing processes can be provided for the selected element, and all other elements employ those known to those skilled in the art of the present invention. As will be apparent to those skilled in the art, many of the examples provided have suitable alternatives that may be utilized.

  FIG. 1 shows an illustrative dual syringe injector 10. The dual syringe injector includes a main control panel 15 and an injection head 20. The injector 10 can inject multiple medical fluids through a catheter and into a patient's blood vessel. As shown, a first medical fluid reservoir 25 is attached to the infusion head 20 and a second medical fluid reservoir 30 is also attached to the infusion head 20. In a preferred embodiment, the medical fluid reservoir 25 contains a sterile contrast agent bottle, and the medical fluid reservoir 30 contains a sterile diluent, eg, a saline bag. Although the injector 10 of FIG. 1 is a dual syringe injector, it should be emphasized that embodiments of the present invention may involve other types of injectors, such as single syringe injectors or other types of injectors. Is to get.

  The injection head 20 can include various components. For example, the injection head 20 includes a secondary control panel 35, first and second syringe / plunger assemblies 40 and 45, and various valve / air detection assemblies. The injector 10 can draw fluid from the medical fluid reservoir 25 into the syringe / plunger assembly 40 and, further, fluid from the medical fluid reservoir 30 via the tube 55 into the syringe / plunger assembly 45. You can pull in. The syringe / plunger assembly 40 can drive medical fluid into the output tube 60 and the syringe / plunger assembly 45 can drive medical fluid into the output tube 65. The output tubes 60, 65 can include a reusable part and a disposable part. Thus, the disposable parts of the output tubes 60, 65 are coupled to the patient's catheter and are discarded after the patient's treatment. The reusable part is the tube part coupled directly to the output part of the syringe / plunger assembly 40, 45. The reusable part and the disposable part may be coupled by a fluid connector.

  The injector 10 further includes both a main control panel 15 and a secondary control panel 35. The operator of the injector 10 can use the main control panel 15 to set up one or more parameters of the injection procedure before starting the procedure. An operator may use the main control panel 15 to modify one or more features, parameters, etc. of the infusion procedure during the procedure, or use the main control panel 15 to pause the infusion procedure. May resume, terminate, and begin a new procedure. The main control panel 15 can display various infusion related information such as flow rate, volume, pressure, rise time, treatment type, fluid information, and patient information to the operator. The secondary control panel 35 can provide a subset of the functions provided by the main control panel 15. For example, the operator may use the secondary control panel 35 to manage the injector setup. The operator can manage the injector setup by interacting with the secondary control panel 35. The secondary control panel 35 may display guidance setup instructions that assist in this process.

  2A-2B show the syringe / plunger assembly 40, 45 in more detail. In FIG. 2A, the syringe 70 is housed by the syringe chamber 75 of the syringe / plunger assembly 45. In FIG. 2B, the syringe 70 is not present in the syringe chamber 75. If a given infusion procedure requires the presence of a syringe 70 in the syringe chamber 75, the configuration of FIG. 2A is appropriate. Similarly, if the procedure requires the absence of a syringe in syringe chamber 75, the configuration of FIG. 2B is appropriate. On the other hand, if the procedure requires the absence of a syringe in the syringe chamber 75, the configuration of FIG. 2A is inappropriate, and if the procedure requires the presence of a syringe in the syringe chamber 75, FIG. The configuration of is inappropriate. As described in more detail below, it may be advantageous to automatically determine whether a syringe is loaded in the syringe chamber required by a particular procedure.

  The function of the exemplary syringe / plunger assembly 105 will be discussed in the context of FIGS. As shown, the syringe / plunger assembly 105 includes a syringe chamber 110, a ram 115, a spud 120, and a motor 125. The syringe chamber 110 can include an inflow port 126 and an outflow port 127. In FIG. 3A, the syringe 130 is accommodated in the syringe chamber 110. The syringe 130 can include a wiper 135. As described in more detail below, the wiper is engaged by the spud 120 of the syringe / plunger assembly 105 during the infusion operation. The syringe 130 may include an inflow opening 136 that coincides with the inflow port 126 of the syringe chamber 110 as well as an output opening 137 that coincides with the outflow port 127 of the syringe chamber 110. In FIG. 3B, there is no syringe in the syringe chamber 110.

  The motor 125 can include a linear actuator. The linear actuator drives the ram 115 in both the forward direction AD and the reverse direction RD. The motor 125 can be configured to drive the ram 115 through the entire syringe chamber 110 from the proximal end 111 to the distal end 112. The degree to which the motion of the ram 115 is resisted is how hard the motor 125 has to work to drive the ram 115 and how much current is required by the motor 125 to drive the ram 115. Influences. In many embodiments, the current required by motor 125 is directly proportional to the resistance of ram 115 motion. For example, the determination of resistance pressure can involve in the form of a slope / intercept formula: y = mx + b. In this equation, y represents motor current, x represents resistance pressure, and m and b are constants derived for each injector during the manufacturing / calibration process. Therefore, the solution of x is as follows: x = (y−b) / m.

  Referring to FIG. 3A, once it is confirmed that the syringe 130 exists in the syringe chamber 110, the motor 125 may drive the ram 115 in the forward direction AD until the spud 120 engages the wiper 135 of the syringe 130. it can. As the ram 115 abuts the wiper 135, the resistance to movement of the ram 115 increases, thereby increasing the amount of current required by the motor 125. As the ram 115 pushes the spud 120 into the wiper 135, the periphery of the wiper 135 forms a flange 140 by wrapping the spud 120. In this way, the ram 115 can push the wiper 135 in the forward direction AD and pull the wiper 135 in the backward direction RD.

  When the ram 115 engages the wiper 135, the syringe 130 can be filled with medical fluid and the medical fluid can be injected through the catheter into the patient's blood vessel. To fill the syringe 130 with medical fluid, the motor 125 can drive the ram 115 in the forward direction AD until the leading edge of the wiper 135 approaches the distal end 112 of the syringe chamber 110. During this step, the frictional force between the wiper 135 and the inner wall of the syringe 130 resists the movement of the ram 115. In a preferred embodiment, this friction force may be about 55 to 65 pounds. The outflow port 127 of the syringe chamber 110 can be sealed, and the inflow port 126 can be in fluid communication with a medical fluid source. The motor 125 can then retract the ram 115 and the wiper 135 in the retracting direction RD, thereby creating a negative pressure within the syringe 130 between the wiper 135 and the distal end 112. This negative pressure draws medical fluid into the syringe 130 through the inflow port 126 and the inflow opening 136. As the ram 115 and wiper 135 are fully retracted, the syringe 130 is filled with medical fluid. The inflow port 126 can be sealed and the outflow port 127 can be in fluid communication with the catheter for injecting medical fluid from the syringe 130 into the patient's blood vessel through the catheter. The motor 125 can then push the medical fluid from the syringe 130 through the outflow opening 137 and the outflow port 127 by driving the ram 115 and wiper 135 again in the forward direction AD.

  FIG. 4 illustrates an example syringe / plunger assembly 205 that can be used in some embodiments of the present invention. The motor 125 and ram 115 of FIG. 4 may be the same as those of FIGS. However, as shown, the spud 220 of FIG. 4 and the distal end 212 of the syringe chamber 210 are different from those of FIGS. Referring to FIG. 4, the front / distal edge of the spud 220 has a conical shape. This conical shape corresponds to the distal end 212 of the syringe chamber 210. The motor 125 can drive the ram 115 in the forward direction AD or the reverse direction RD, thereby driving the spud 220 between the proximal end 211 and the distal end 212 of the syringe chamber. Unlike the syringe chamber 110 of FIGS. 3A-3B where the inflow port 126 is separate from the outflow port 127, the syringe chamber 210 of FIG. 4 includes a single inflow / outflow port 228 through which the medical The working fluid can be guided in either direction.

  FIG. 5 is a block diagram illustrating an example injection system 400 according to an embodiment of the present invention. The injection system can include an injector 405 and an injector control system 410. The injector 405 can include one or more syringe chambers along with one or more rams and one or more motors. The syringe chamber, ram, and motor may have the same or similar characteristics as those discussed elsewhere herein.

  The injector control system 410 can include a programmable processor 415 and a storage device 420. The storage device can store various software modules designed for specific functions. As shown in FIG. 5, the storage device 420 includes a ram operation data module 425, a resistance detection module 430, a work condition detection module 435, and an injection process module 440. The software modules stored by the storage device 420 can vary depending on a variety of factors, such as the type of injector 405 and the type of injection process. A number of additional software modules can be stored by the storage device 420 and / or the functions of the various software modules can be modified to suit a particular application.

  When executed by the programmable processor 415, the ram motion data module 425 causes the programmable processor 415 to collect a set of ram motion information for each ram. The ram motion information indicates that the ram is moving forward or backward in the syringe chamber. The infusion process module 440 can instruct the programmable processor 415 to move the ram according to the injector work process (eg, syringe filling process, pre-saline infusion to check extravasation, etc.). The ram motion data module 425 can assist the programmable processor 415 in confirming that the ram is indeed running. In some implementations, the ram motion information includes the ram position (eg, spud position) relative to a reference point, eg, the proximal or distal end of the syringe chamber. For example, to detect whether a syringe is present, the injector control system 410 determines whether the spud has advanced far enough from its rest position to abut the syringe wiper if a syringe is present. Can be confirmed. In another example, to detect whether the syringe wiper is misaligned, the injector control system 410 may cause the spud to be near the distal end of the syringe chamber (where the misaligned wiper front end is the syringe The ram resistance level when it is located at the distal end of the In some embodiments, the ram motion information includes the duration that the ram has moved (eg, from a reference time marker such as when the ram begins to retract from the time the ram first moved from the rest position). Duration). For example, if it is known that the ram will retract X seconds to begin the syringe filling process, the injector control system 410 may determine whether an appropriate vacuum has been created within the syringe chamber. The ram resistance can be monitored after X seconds. In some implementations, the ram motion information includes the speed at which the ram moves or accelerates. In some implementations, the ram motion information includes other information related to ram motion that corresponds to one or more injector work conditions.

  When executed by the programmable processor 415, the resistance detection module 430 can cause the programmable processor 415 to collect a set of resistance information for each ram. The resistance information set indicates how much resistance the ram moves in the forward or backward direction of the ram. For systems where one or more motors are configured to drive one or more rams, the first resistance information set requires how much current is required by the motors to drive the rams Can be included. In some implementations, the resistance information is based on parameters other than motor current, such as ram acceleration.

  When executed by the programmable processor 415, the work condition detection module 435 may cause the programmable processor 415 to detect one or more injector work conditions. The work situation detection module 435 can cause the programmable processor 415 to receive the ram operation information set from the ram operation data module 425 and to receive the resistance information set from the resistance detection module 430. Programmable processor 415 then determines whether there is one or more of several injector work conditions based on the ram motion information set and resistance information set due to work condition detection module 435. Can be judged.

  The work condition detection module 435 can cause the programmable processor 415 to monitor one or more of various injector work conditions. For example, one such situation is a situation where the syringe sleeve is misaligned during operation. The syringe sleeve acts as a door that allows access to the syringe chamber. If the syringe sleeve is not properly closed (eg, due to a syringe misalignment), the spud is pressed against the syringe sleeve during ram advancement or pulled into the syringe sleeve during ram retraction, causing considerable damage. May cause. The work status detection module 435 sends to the programmable processor 415 ram operational information (eg, is the spud near the proximal or distal end of the syringe chamber) and resistance information (eg, to an abnormally high level of motor current). Can be monitored for improper contact of the ram with the syringe sleeve. Another example situation that can be observed by the programmable processor 415, prompted by the work condition detection module 435, is whether or not there is a blockage in the syringe (eg, a skin-like contrast agent, a syringe manufacturing anomaly). If the resistance to ram movement is increased when the ram is normally in a position where resistance is minimal, the work condition detection module 435 may cause the programmable processor 415 to have the syringe occluded. Can be suggested. Another example of a situation that can be monitored is whether the syringe wiper is misaligned inside the syringe barrel. As implied above, if the syringe wiper is not coaxially aligned with the syringe barrel, a portion of the syringe wiper may initially contact the distal end of the syringe barrel. This can cause the syringe wiper to collapse, and as a result, a new syringe must be reloaded and the process resumed, resulting in a significant waste of time. If the ram motion information and resistance information indicate, for example, that resistance to ram movement is increased as the spud approaches the distal end of the syringe chamber, the work status detection module 435 may indicate to the programmable processor 415 It can be suggested that the syringe wiper is misaligned.

  In the preferred embodiment, the work condition detection module 435 can cause the programmable processor 415 to determine whether a syringe is present in the syringe chamber by making a conclusion based on the resistance pressure experienced by the ram during advancement. . If the first resistance information set indicates that the forward movement of the first ram is resisted by a pressure greater than a predetermined amount, the work condition detection module 435 can be programmed to indicate that the syringe is in the first syringe chamber. The processor 415 can conclude. In this case, it can be concluded that the resistance pressure is applied by the wiper of the syringe, ie that the syringe is indeed present. If the first resistance information set indicates that the forward movement of the first ram is resisted by a pressure less than a predetermined amount, the work status detection module 435 can be programmed to indicate that no syringe is present in the first syringe chamber. The processor 415 can conclude. In this case, it can be concluded that the ram is moving unimpeded by the syringe wiper, ie that there is no syringe.

  The amount of ram resistance pressure that indicates syringe presence may vary between embodiments. In many embodiments, about 55-65 psi is required to move the syringe wiper from its rest position. Thus, in such an embodiment, setting the predetermined amount of pressure to less than 55 psi (eg, 10 psi) can provide the desired effect.

  When executed by the programmable processor 415, the infusion process module 440 causes the programmable processor 415 to perform a variety of functions associated with injecting medical fluid into a patient's blood vessel. As mentioned above, the injection process is preferably as automated as possible. By automatically detecting the presence or absence of a syringe in the syringe chamber, the injection process can be enhanced. Specifically, in some embodiments, the injection process module 440 may cause the programmable processor 415 to automatically initiate a syringe filling process if it is determined that a syringe is present in each syringe chamber. it can. In some embodiments, the injection process module 440 includes: (a) a syringe is not present in each syringe chamber; (b) a syringe sleeve is misaligned; (c) a syringe wiper is coaxial with the syringe barrel. If it is determined that (d) the inside of the syringe is blocked, the programmable processor 415 can stop the injection process and alert the operator.

  In some implementations, the work status detection module 435 can cause the programmable processor 415 to monitor the injector work status while the injector is injecting contrast agent into the patient's blood vessel. For example, one such situation is injection overpressure. If the ram operating information and / or resistance information indicates an abnormally high resistance during injection, the injection process module 440 may cause the programmable processor 415 to stop the injection process and alert the operator. This and similar functions of the work status detection module 435 can significantly increase patient safety.

  The injector control system 410 can be placed in a wide variety of locations. In a preferred embodiment, the injector control system 410 can be located within the injector 405 itself. In some implementations, the injector control system 410 can be located separately from the injector 405. In some implementations, the injector control system 410 can be located on a server remote from the injector 405 and can communicate with the injector 405 via a network 445 (eg, the Internet). In such an embodiment, the operator can enter commands into the control panel, and the injector components can package the commands and send them over the network 445 to the injector control system 410. And the injector control system 410 can initiate a response action and communicate that action to the injector 405 via the network 445.

  FIG. 6 illustrates an example method that can be implemented in accordance with an embodiment of the present invention. As shown, the method includes providing an injector (505) with characteristics similar to those discussed elsewhere herein. Although the method of FIG. 6 involves at least two syringe chambers, a motor, and a ram, it will be appreciated that the principles shown and discussed herein can be incorporated into a method for use with a single syringe injector. Yes.

  The method of FIG. 6 includes moving the first ram (510) and moving the second ram (515). For example, the method can include moving a first ram in a forward direction by a first distance within a first syringe chamber of an injector. Similarly, the method can include moving the second ram in the forward direction by a second distance within the second syringe chamber of the injector. In a preferred embodiment, moving the ram in the forward direction can include driving the ram with a motor.

  As the ram is moved (510, 515), its resistance to movement can be measured. The method can include measuring 520 how much the movement of the first ram in the forward direction is resisted. Similarly, the method can include measuring 525 how much the movement of the second ram in the forward direction is resisted. As discussed elsewhere herein, in an embodiment in which moving the ram forward includes driving the ram with a motor, measuring how much the movement is resisted is , Measuring how much current the motor needs to drive the ram.

  In the method of FIG. 6, it can be determined whether the first ram has moved a first distance (530) and whether the second ram has moved a second distance (535). In many embodiments, the ram must move at least a threshold distance before it can be concluded regarding the presence or absence of a syringe in each syringe chamber. For example, if the ram travel distance is less than the threshold distance, the ram may not yet move to where the syringe wiper is. In that case, there may be a false conclusion that the syringe is not present. For this reason, and for other similar reasons, a number of implementations are involved in determining whether each ram has moved a threshold distance. If the first ram is not moving the first distance, the first ram can be moved again (510), and if the second ram is not moving the first distance, the second ram is moved again (515). )be able to.

  If the ram is moving a threshold distance (eg, a distance sufficient to abut the syringe wiper if present), a determination can be made regarding the presence or absence of a syringe in each syringe chamber. It can be determined whether the resistance of movement of the first ram exceeds a first predetermined amount (540) and whether the resistance of movement of the second ram exceeds a second predetermined amount (545). If movement in the forward direction of the first ram is resisted by a pressure less than the first predetermined amount, it can be concluded (550) that there is no syringe in the first syringe chamber. On the other hand, if the movement in the forward direction of the first ram is resisted by a pressure greater than or equal to the first predetermined amount, it can be concluded (555) that a syringe is present in the first syringe chamber. Similarly, if movement in the forward direction of the second ram is resisted by a pressure greater than or equal to a second predetermined amount, it can be concluded (560) that a syringe is present in the second syringe chamber. On the other hand, if the movement of the second ram in the forward direction is resisted by a pressure less than the second predetermined amount, it can be concluded (565) that there is no syringe in the second syringe chamber. In some embodiments, the first predetermined amount of pressure and the second predetermined amount of pressure are both about 10 psi.

  In the preferred embodiment, subsequent actions can be taken automatically based on a determination of whether a syringe is present in the syringe chamber. As shown, if it is concluded (550) that the syringe is not present in the first syringe chamber, the operator can be alerted (570), and it is concluded that the syringe is not present in the second syringe chamber ( 565), the operator can be warned (585). Once it is concluded that a syringe is present in the first syringe chamber (555), the syringe filling process can be automatically initiated for that syringe (575), and the syringe is present in the second syringe chamber. Is concluded (560), the syringe filling process can be automatically initiated for the syringe (580). Depending on the injector type, the injection procedure, and a variety of other factors, other subsequent actions can also occur automatically based on the determination of whether a syringe is present in the syringe chamber.

  It should be emphasized that the method shown in FIG. 6 is for illustration purposes only. Any of the functions discussed herein in the context of the system (see FIG. 5) can be performed by the method (and vice versa). The monitoring method of the injector work status other than the presence or absence of the syringe is also involved in the same step. The step order provided in the method shown in FIG. 6 is for illustrative purposes only, and other orders for accomplishing the listed functions are within the scope of the present invention. Any of the functions discussed anywhere in this specification can be implemented in the method shown in FIG.

  Aspects and features of the invention (eg, those discussed herein in connection with the system of FIG. 5 and / or the method of FIG. 6) can be implemented on a computer-readable medium. The computer readable medium can be an electronic, optical, magnetic, or other storage device or a transmitter that can provide computer readable instructions to a programmable processor. Examples of computer readable media are floppy disk, CD-ROM, magnetic disk, memory chip, ROM, RAM, ASIC, configured processor, any type of optical media, any type of magnetic tape, or other magnetic media, or computer Including any other medium from which the processor can read instructions.

  The medium may be programmed to include instructions for preparing an injector (an injector having one or more characteristics of an injector discussed elsewhere herein) in operation. it can. The medium can include instructions for causing the programmable processor to receive one or more ram advancement information sets depending on the number of rams and syringe chambers included in the syringe. Each advance information set may indicate that the corresponding ram of the injector has moved a given distance in the forward direction within the corresponding syringe chamber of the injector. Ram advancement information can include information discussed herein in connection with moving the ram in the forward direction.

  The medium can also include instructions for causing the programmable processor to receive one or more sets of resistance information, again depending on the number of rams and syringe chambers included in the injector. Each set of resistance information can indicate how much the forward movement of the corresponding ram was resisted. In the preferred embodiment, the resistance information set can include how much current was required by the injector motor to drive the corresponding ram in the corresponding syringe chamber. The resistance method can include the information discussed herein in relation to how much forward movement of the ram is resisted.

  The medium can include instructions for causing the programmable processor to determine whether a syringe is present in each syringe chamber based on the ram advancement information set and the resistance information set. In a preferred embodiment, the instructions for causing the programmable processor to determine whether a syringe is present in the syringe chamber include instructions for causing the programmable processor to conclude based on a predetermined amount of pressure. If the resistance information set indicates that the forward movement of the corresponding ram has been resisted by more than a predetermined amount of pressure, the processor can conclude that the syringe is in the syringe chamber. On the other hand, if the resistance information set indicates that the forward movement of the corresponding ram has been resisted by less than a predetermined amount of pressure, the processor can conclude that the syringe is not in the syringe chamber. In a particularly preferred embodiment, the predetermined amount of pressure to be used for each resistance information can be about 10 psi. The principles for making this determination are discussed in more detail elsewhere herein.

  As described above, a determination can be made regarding subsequent actions based on the presence or absence of a syringe. The medium can include instructions for causing the programmable processor to initiate the syringe filling process if it is determined that the syringe is present in the first syringe chamber. The medium can include instructions for causing the programmable processor to alert the operator if it is determined that the syringe is not present in the first syringe chamber. As discussed elsewhere herein, other instructions for causing the programmable processor to take subsequent actions can also be incorporated into computer-readable media.

  In some aspects, the computer readable medium can be programmed to have instructions for detecting injector work conditions. The medium can include instructions for causing a programmable processor to receive a first set of ram motion information relating to movement of the first ram of the injector within the first syringe chamber of the injector. The medium can include instructions for causing the programmable processor to receive a first resistance information set that indicates how much the movement of the first ram has been resisted. The medium can include instructions for causing the programmable processor to determine whether a first injector work condition exists based on the first ram motion information set and the first resistance information set. In a preferred embodiment, the first resistance information set can include how much current is required by the injector motor to drive the first ram during movement of the first ram.

  In some preferred embodiments, the first injector operating condition includes the presence of the first syringe in the first syringe chamber. Some such embodiments may be that the first syringe is present in the first syringe chamber if the first resistance information set indicates that the movement of the first ram is resisted by a pressure greater than or equal to a predetermined amount. Includes instructions for causing the programmable processor to conclude. Some such embodiments may indicate that the syringe is not present in the first syringe chamber if the first resistance information set indicates that the movement of the first ram has been resisted by a pressure less than a predetermined amount. Contains instructions to cause the programmable processor to conclude. In some such implementations, the medium can further include instructions for causing the programmable processor to initiate the syringe filling process if it is determined that the first syringe is present in the first syringe chamber.

  In some implementations, the medium further includes instructions for causing the programmable processor to determine whether a second injector work situation exists. In a preferred embodiment, the second injector work situation includes the second syringe being in the second syringe chamber of the injector. In such an embodiment, the programmable processor may receive a second set of ram motion information regarding the motion of the second ram of the injector within the second syringe chamber of the injector. In such an embodiment, the programmable processor may receive a second resistance information set that indicates how much the movement of the second ram was resisted. In many such implementations, the programmable processor can determine whether a second syringe is present in the second syringe chamber based on the second ram motion information set and the second resistance information set. . In some implementations, the programmable processor can determine whether a second injector work condition exists based on the first ram motion information set and the first resistance information set.

  As discussed elsewhere herein, the injector operating status detected by embodiments of the present invention is that the first syringe is present in the first syringe chamber. The syringe sleeve is not properly closed for operation, the wiper of the first syringe is misaligned with the cylinder of the first syringe, the inside of the syringe is clogged, and the overpressure during injection You can choose from.

  In some embodiments, the present invention can be embodied in the form of a method. The method can include providing an injector having one or more of the features discussed herein, including a first syringe chamber and a first ram. The method can include moving the first ram in the forward and / or backward direction within the first syringe chamber. The method can measure how much the movement of the first ram is resisted. In many preferred embodiments, measuring how much the movement of the first ram is resisted includes measuring the current supplied to the motor that drives the movement of the first ram. In many preferred embodiments, the method is based on one or more kinematic characteristics of the first ram and based on how much the movement of the first ram is resisted. Including concluding that it exists. Examples of injector operating conditions are: the first syringe is present in the first syringe chamber, the syringe sleeve in the first syringe chamber is not properly closed for operation, the wiper of the first syringe is It includes misalignment with the barrel of one syringe, blockage inside the syringe, and excessive pressure during injection.

  As described above, in some embodiments, the first injector operating condition is that the first syringe is present in the first syringe chamber. One or more motion characteristics of the first ram include the first ram moving a first distance. How much the movement of the first ram is resisted includes that the movement of the first ram is resisted by a pressure greater than a first predetermined amount. In some such embodiments, the method can further include automatically initiating the syringe filling process once it is concluded that the first syringe is present in the first syringe chamber.

  Some embodiments involve monitoring the status of multiple injector operations. Some injectors include a second syringe chamber and a second ram. In this regard, the method further includes moving the second ram a second distance within the second syringe chamber and measuring how much the movement of the second ram is resisted. In addition, in this regard, the method may indicate that the second syringe is present in the second syringe chamber if the movement of the second ram is resisted by a pressure greater than a second predetermined amount, or the second ram. If the movement is resisted by a pressure less than the second predetermined amount, it can be concluded that no syringe is present in the second syringe chamber.

  In some embodiments, the present invention can be embodied in the form of an infusion system. The injection system can include an injector as discussed herein, including a first syringe chamber and a first ram. The injection system can also include an injector control system having a processor and a storage device, which can include a ram motion data module, a resistance detection module, and a work condition detection module. When executed by the processor, the ram motion data module causes the processor to collect a first set of ram motion information relating to the motion of the first ram in the first syringe chamber. When executed by the processor, the resistance detection module causes the processor to collect a first resistance information set that indicates how much the movement of the first ram is resisted. When executed by the processor, the work status detection module causes the processor to receive a first ram motion information set from the ram motion data module, a first resistance information set from the resistance detection module, and a first ram advance information set. Based on the first resistance information set, it is determined whether or not the first injector working condition exists. In some preferred injection systems, the injector includes a motor configured to drive the first ram, and the first resistance information set requires how much current is required by the motor to drive the first ram. Or is included. Examples of ram motion information sets include the position of the first ram relative to a reference point, the duration that the first ram is moving, the speed at which the first ram moves or accelerates, and so on.

  In some implementations, the work status detection module, when executed by the processor, can cause the processor to determine whether a first syringe is present in the first syringe chamber. In many embodiments, if the first resistance information set indicates that the movement of the first ram is resisted by more than a predetermined amount of pressure, then conclude that the first syringe is present in the first syringe chamber. Can do. Similarly, in many embodiments, if the first resistance information set indicates that the movement of the first ram is resisted by a pressure less than a predetermined amount, it is concluded that the syringe is not in the first syringe chamber. be able to. In some embodiments, the storage device further includes an infusion process module that, when executed by the processor, determines that the first syringe is present in the first syringe chamber, the syringe in the processor. Automatically start the filling process.

  In the foregoing detailed description, specific embodiments of the invention have been described. However, it will be appreciated that various modifications and changes may be made without departing from the scope of the invention as set forth in the appended claims. Thus, some of the features of the preferred embodiments described herein are not necessarily included in the preferred embodiments of the invention intended for alternative uses.

Claims (20)

  1. A computer readable medium programmed to have instructions for detecting injector operating conditions, the medium being on a programmable processor:
    (A) receiving a first ram motion information set relating to movement of the first ram of the injector within the first syringe chamber of the injector;
    (B) receiving a first resistance information set indicating how much the movement of the first ram was resisted; and (c) a first injection based on the first ram motion information set and the first resistance information set. Including an instruction to determine whether a vessel work situation exists,
    Computer readable medium.
  2.   The medium of claim 1, wherein the first injector operating condition includes a first syringe being present in the first syringe chamber.
  3.   (I) if the first resistance information set indicates that the movement of the first ram is resisted by a pressure greater than or equal to a predetermined amount, the first syringe is present in the first syringe chamber; ii) If the first resistance information set indicates that the movement of the first ram has been resisted by a pressure less than a predetermined amount, the programmable processor is informed that no syringe is present in the first syringe chamber. The medium of claim 2, comprising instructions for concluding.
  4.   The medium of claim 2, further comprising: (d) instructions for causing the programmable processor to initiate a syringe filling process if it is determined that the first syringe is present in the first syringe chamber.
  5. further,
    (D) receiving a second ram motion information set relating to movement of the second ram of the injector within the second syringe chamber of the injector;
    (E) receiving a second resistance information set indicating how much the movement of the second ram was resisted; and (f) a second syringe based on the second ram motion information set and the second resistance information set. 3. The medium of claim 2, comprising determining whether or not is present in the second syringe chamber.
  6.   The medium of claim 1, wherein the first resistance information set includes how much current is required by the injector motor to drive the first ram during movement of the first ram.
  7.   And (d) instructions for causing the programmable processor to determine whether a second injector work condition exists based on the first ram motion information set and the first resistance information set. Item 10. The medium according to Item 1.
  8.   The first injector operating status is that the first syringe is present in the first syringe chamber, the syringe sleeve of the first syringe chamber is not properly closed for operation, the first syringe The medium of claim 1, wherein the wiper is selected from the group consisting of misalignment with the barrel of the first syringe, occlusion within the syringe, and excess pressure during injection.
  9. (A) providing an injector comprising (i) a first syringe chamber and (ii) a first ram;
    (B) moving the first ram in the forward and / or backward direction within the first syringe chamber;
    (C) measure how much the movement of the first ram is resisted; and (d) based on one or more movement characteristics of the first ram and how much the movement of the first ram is Conclude that there is a first injector working condition based on whether it is resisted,
    A method involving that.
  10. The first injector work situation is that the first syringe is present in the first syringe chamber;
    The one or more kinematic characteristics of the first ram include that the first ram is moving a first distance, and how much the movement of the first ram is resisted is the first ram. The ram movement is resisted by a pressure greater than or equal to a first predetermined amount;
    The method of claim 9.
  11.   The method of claim 10, further comprising automatically initiating a syringe filling process when it is concluded that the first syringe is present in the first syringe chamber.
  12. The injector further includes (iii) a second syringe chamber and (iv) a second ram, and the method further includes:
    (E) moving the second ram a second distance within the second syringe chamber;
    (F) measuring how much the movement of the second ram is resisted; and (g) (i) if the movement of the second ram is resisted by a pressure greater than a second predetermined amount, That the syringe is present in the second syringe chamber, or (ii) if the movement of the second ram is resisted by a pressure less than a second predetermined amount, the syringe is not present in the second syringe chamber. 11. The method of claim 10, comprising concluding.
  13.   10. The method of claim 9, wherein measuring how much the movement of the second ram is resisted includes measuring a current supplied to a motor that drives the movement of the first ram.
  14.   The first injector operating status is that the first syringe is present in the first syringe chamber, the syringe sleeve of the first syringe chamber is not properly closed for operation, the first syringe 10. The method of claim 9, wherein the wiper is selected from the group consisting of misalignment with the barrel of the first syringe, occlusion within the syringe, and excess pressure during injection.
  15. Infusion system:
    (A) an injector including a first syringe chamber and a first ram;
    (B) an injector control system including a processor and a storage device;
    The storage device includes a ram motion data module, a resistance detection module, and a work status detection module;
    (I) the ram motion data module, when executed by the processor, causes the processor to collect a first ram motion information set relating to the motion of the first ram in the first syringe chamber;
    (Ii) the resistance detection module, when executed by the processor, causes the processor to collect a first set of resistance information indicating how much the movement of the first ram is resisted; and
    (Iii) When the work status detection module is executed by the processor,
    (A) receiving the first ram motion information set from the ram motion data module;
    (B) receiving the first resistance information set from the resistance detection module; and (C) based on the first ram advancement information set and the first resistance information set, whether there is a first injector work situation To determine whether or not
    Injection system.
  16. When the work status detection module is executed by the processor,
    If the first resistance information set indicates that the movement of the first ram is resisted by a pressure greater than or equal to a predetermined amount, the first syringe is present in the first syringe chamber, or the first If the first resistance information set indicates that the ram motion is resisted by less than a predetermined amount of pressure, by concluding that no syringe is present in the first syringe chamber,
    Causing the processor to determine whether a first syringe is present in the first syringe chamber;
    16. An injection system according to claim 15.
  17.   The storage device further includes (iv) an infusion process module that, when executed by the processor, concludes that the first syringe is present in the first syringe chamber, the processor. The injection system of claim 16, wherein the injection system automatically initiates the syringe filling process.
  18.   The injector further includes a motor configured to drive the first ram, and the first resistance information set requires how much current is required by the motor to drive the first ram. 16. An injection system according to claim 15 comprising
  19.   The first injector operating status is that the first syringe is present in the first syringe chamber, the syringe sleeve of the first syringe chamber is not properly closed for operation, the first syringe 16. The injection system of claim 15, wherein the wiper is selected from the group consisting of misalignment with the barrel of the first syringe, occlusion within the syringe, and excess pressure during injection.
  20. The first ram motion information set is:
    The position of the first ram with respect to a reference point;
    16. The infusion system of claim 15, comprising one or more of a duration that the first ram is moving and a speed at which the first ram is moving or accelerating.
JP2013554480A 2011-02-15 2012-02-08 Monitoring of power injector operations via motor current measurement Pending JP2014510575A (en)

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US201161443030P true 2011-02-15 2011-02-15
US61/443,030 2011-02-15
US13/115,719 US20120204997A1 (en) 2011-02-15 2011-05-25 Monitoring injector operation
US13/115,719 2011-05-25
PCT/US2012/024216 WO2012112347A1 (en) 2011-02-15 2012-02-08 Monitoring operation of a power injector via motor current measurement

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WO2014047626A2 (en) 2012-09-24 2014-03-27 Angiodynamics, Inc. Power injector device and method of use
CN107490716A (en) * 2017-07-11 2017-12-19 苏州首达机械有限公司 The detection method of piston type racking machine

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US4854324A (en) * 1984-01-31 1989-08-08 Medrad, Inc. Processor-controlled angiographic injector device
US5425716A (en) * 1991-08-09 1995-06-20 Atom Kabushiki Kaisha Infusion apparatus
US7267666B1 (en) * 1995-04-20 2007-09-11 Acist Medical Systems, Inc. Angiographic injector system with multiple processor redundancy
US6673033B1 (en) * 1999-11-24 2004-01-06 Medrad, Inc. Injectors, injector systems and injector control
US6958053B1 (en) * 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US7308300B2 (en) * 2001-05-30 2007-12-11 Acist Medical Systems, Inc. Medical injection system
WO2007033103A1 (en) * 2005-09-14 2007-03-22 Acist Medical Systems, Inc. Medical fluid injection system
EP2469437A1 (en) 2005-11-21 2012-06-27 ACIST Medical Systems, Inc. Medical fluid injection system with stored injection parameters
US8409134B2 (en) * 2008-08-26 2013-04-02 Mallinckrodt Llc Power injector having calibrated pressure monitoring functionality

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WO2012112347A1 (en) 2012-08-23

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