WO2014049745A1 - Liquid administration device - Google Patents

Liquid administration device Download PDF

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Publication number
WO2014049745A1
WO2014049745A1 PCT/JP2012/074772 JP2012074772W WO2014049745A1 WO 2014049745 A1 WO2014049745 A1 WO 2014049745A1 JP 2012074772 W JP2012074772 W JP 2012074772W WO 2014049745 A1 WO2014049745 A1 WO 2014049745A1
Authority
WO
WIPO (PCT)
Prior art keywords
housing
drive gear
gear
plunger
administration device
Prior art date
Application number
PCT/JP2012/074772
Other languages
French (fr)
Japanese (ja)
Inventor
滋晃 冨家
正臣 今井
学 有延
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to PCT/JP2012/074772 priority Critical patent/WO2014049745A1/en
Publication of WO2014049745A1 publication Critical patent/WO2014049745A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M2005/14533—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons cam actuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force

Definitions

  • the present invention relates to a liquid administration device.
  • Patent Document 1 a prefilled syringe that is filled with a chemical solution aseptically and that can administer the chemical solution is known (for example, see Patent Document 1).
  • the prefilled syringe is a syringe outer cylinder having a mouth part for discharging a chemical solution, a needle tube provided at the mouth part of the syringe outer cylinder and having a sharp needle tip at the tip, a gasket capable of sliding in the syringe outer cylinder, A drug solution filled in a space surrounded by the syringe outer cylinder and the gasket, and a plunger connected to the proximal end side of the gasket and pressing the gasket toward the distal end to discharge the drug solution from the mouth.
  • the needle tube is punctured into the living body, and the plunger is pressed in this punctured state.
  • medical solution will be discharged from a mouth part with a gasket, Therefore The said chemical
  • the object of the present invention is to reduce the force required for liquid administration, to easily reduce the liquid administration speed, and to easily apply liquid to a user who is difficult to press the plunger.
  • the object is to provide a liquid administration device that can be administered.
  • the present invention is provided with a syringe having a discharge port provided at a tip end, filled with a liquid and having a cylindrical shape, and a gasket slidably installed in the outer tube, and the discharge port
  • a liquid administration device for administering the liquid via A housing having a mounting portion to which the syringe is mounted at a tip portion;
  • a drive gear provided with a drive rotary shaft and installed in the housing so as to be rotatable around the drive rotary shaft, and at least a part of the drive gear protrudes from the housing and is operated to rotate the drive gear.
  • a reduction mechanism that reduces the rotational speed of the drive gear and transmits the rotational force of the drive gear to the rack;
  • By rotating the drive gear by operating the operation unit in a mounted state in which the syringe is mounted on the mounting unit, the rotational speed of the drive gear is reduced by the reduction mechanism, and the drive gear
  • a liquid administration device wherein a rotational force is transmitted to the rack, the plunger moves in a distal direction, and the plunger pushes the gasket in the distal direction to move in the distal direction. is there.
  • the speed reduction mechanism is rotatably installed in the housing, includes a speed reduction rotation shaft, and rotates about the speed reduction rotation shaft by rotation of the drive gear.
  • the gear wheel has a smaller pitch circle radius than the first gear, and rotates integrally with the first gear about the reduction rotation shaft, and the rotational force associated with the rotation is transmitted to the rack. It is preferable to provide a gear assembly having a second gear.
  • the pitch circle radius of the first gear is preferably larger than the pitch circle radius of the drive gear.
  • liquid administration device of the present invention it is preferable that a part of the operation portion protrudes to the outside from a side portion on the opposite side of the rack of the housing with the reduction rotation shaft interposed therebetween.
  • the plunger moves in the distal direction. It is preferable that it is comprised.
  • the operation portion is disposed at a base end portion of the housing, and a part of the operation portion protrudes outside from the base end portion of the housing.
  • the distance from the drive rotation shaft to the power point in the operation unit when operating the operation unit is longer than the pitch circle radius of the drive gear.
  • the operation unit has a disk shape.
  • the syringe that is attached to the attachment portion and filled with the liquid in advance.
  • the plunger is moved while being decelerated by the deceleration mechanism, the force required for the liquid administration operation can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably obtained. Can be administered.
  • the liquid administration rate can be easily reduced. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
  • the plunger is moved by rotating the rotating body with the operation unit, for example, even a user who has difficulty with fingers and cannot easily press the plunger directly uses the palm of his hand. By operating the operation unit, the liquid can be easily administered.
  • FIG. 1 is a perspective view showing a first embodiment of the liquid administration device of the present invention.
  • FIG. 2 is a cross-sectional view of the liquid administration device shown in FIG.
  • FIG. 3 is a sectional view of a first housing member of the housing of the liquid administration device shown in FIG. 4 is a cross-sectional view of a second housing member of the housing of the liquid administration device shown in FIG.
  • FIG. 5 is a perspective view of a rotating body of the liquid administration device shown in FIG.
  • FIG. 6 is a perspective view of the gear assembly of the liquid administration device shown in FIG.
  • FIG. 7 is a perspective view of a plunger of the liquid administration device shown in FIG. FIG.
  • FIG. 8 is a perspective view of the outer cylinder and needle tube of the syringe of the liquid administration device shown in FIG.
  • FIG. 9 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG.
  • FIG. 10 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG.
  • FIG. 11 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG. 1.
  • FIG. 12 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG.
  • FIG. 13 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG.
  • FIG. 14 is a cross-sectional view for explaining the operation when using the liquid administration device shown in FIG. FIG.
  • FIG. 15 is a cross-sectional view for explaining an operation when the liquid administration device shown in FIG. 1 is used.
  • FIG. 16 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG.
  • FIG. 17 is a cross-sectional view for explaining the operation when using the liquid administration device shown in FIG.
  • FIG. 18 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG.
  • FIG. 19 is a cross-sectional view showing a second embodiment of the liquid administration device of the present invention.
  • liquid administration device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
  • FIG. 1 is a perspective view showing a first embodiment of the liquid administration device of the present invention.
  • FIG. 2 is a cross-sectional view of the liquid administration device shown in FIG.
  • FIG. 3 is a sectional view of a first housing member of the housing of the liquid administration device shown in FIG. 4 is a cross-sectional view of a second housing member of the housing of the liquid administration device shown in FIG.
  • FIG. 5 is a perspective view of a rotating body of the liquid administration device shown in FIG.
  • FIG. 6 is a perspective view of the gear assembly of the liquid administration device shown in FIG.
  • FIG. 7 is a perspective view of a plunger of the liquid administration device shown in FIG. FIG.
  • FIG. 8 is a perspective view of the outer cylinder and needle tube of the syringe of the liquid administration device shown in FIG. 9 to 12 are perspective views for explaining the procedure for assembling the liquid administration device shown in FIG. 13 to 18 are cross-sectional views for explaining the operation when using the liquid administration device shown in FIG.
  • the upper side in FIGS. 1 to 4 and 7 to 18 is referred to as “base end (rear end)”, the lower side is referred to as “tip”, and the vertical direction is referred to as “axial direction” or “longitudinal direction”.
  • a liquid administration device 1 shown in FIGS. 1 to 18 is a medical instrument used when a liquid is administered (injected) into a living body.
  • the liquid is appropriately selected according to the purpose of use.
  • protein drugs such as antibodies, peptide drugs such as low molecular weight proteins and hormones, nucleic acid drugs, cell drugs, blood products, various infectious diseases Examples include vaccines, anticancer agents, anesthetics, narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, etc. that are mainly injected subcutaneously.
  • the liquid administration device 1 includes a rotating body 3, a gear assembly 4 that is a speed reduction mechanism, a plunger 5, a syringe 6, and a housing 2 that houses them. I have.
  • the housing 2 has a long box shape in the vertical direction in FIG. 1, and an opening is formed at the tip thereof.
  • the housing 2 includes two members, that is, a first housing member 2a and a second housing member 2b joined to each other.
  • four holes 26 are formed in the wall portion of the distal end portion of the first housing member 2a, and the inner surface of the distal end portion of the second housing member 2b is fitted into the four holes 26.
  • Four protrusions 27 are formed. And each 1st housing member 2a and 2nd housing member 2b are joined because each protrusion part 27 fits in each hole 26, respectively.
  • the joining method of the 1st housing member 2a and the 2nd housing member 2b is not restricted to this,
  • fusion such as heat fusion, high frequency fusion, ultrasonic fusion, or an adhesive agent or solvent
  • adhesive agent such as heat fusion, high frequency fusion, ultrasonic fusion
  • solvent such as solvent
  • the housing 2 has a mounting portion 24 to which the syringe 6 is mounted at the tip thereof.
  • the longitudinal direction of the housing 2 and the axial direction of the outer cylinder 7 described later of the syringe 6 coincide with each other, and at least the distal end portion of the needle tube 9 described later of the syringe 6 It protrudes outside from the front-end
  • the entire needle tube 9 protrudes to the outside.
  • the present invention is not limited to this. For example, only the distal end portion of the needle tube 9 may protrude to the outside.
  • the mounting portion 24 has engaging portions 241 and 242 that engage with a flange 71 of an outer cylinder 7 (described later) of the syringe 6 in a mounting state in which the syringe 6 is mounted on the mounting portion 24.
  • the engaging portion 241 is a rib formed on the inner surface of the first housing member 2a
  • the engaging portion 242 is a rib formed on the inner surface of the second housing member 2b.
  • the engaging portions 241 and 242 are arranged so as to face each other with a predetermined distance therebetween. The engagement portions 241 and 242 can prevent the syringe 6 from being detached from the mounting portion 24.
  • the housing 2 has a pair of bearings 21 that rotatably support a shaft portion 33 (described later) of the rotating body 3 and a shaft portion 43 (described later) of the gear assembly 4 at the base end portion thereof. It has a pair of bearings 22 to support. These bearings 21 and 22 are provided such that the shaft portion 33 and the shaft portion 43 are parallel to each other.
  • the bearings 21 are arranged at the base end of the housing 2 so as to be separated from each other by a predetermined distance and to face each other.
  • Each bearing 21 includes a unit support portion 21a formed on the first housing member 2a and a unit support portion 21b formed on the second housing member 2b.
  • the unit support portion 21a and the unit support portion It is formed by abutting 21b.
  • each bearing 22 is arranged at the base end portion of the housing 2 so as to be separated from each other by a predetermined distance and to face each other.
  • Each bearing 22 includes a unit support portion 22a formed on the first housing member 2a and a unit support portion 22b formed on the second housing member 2b. The unit support portion 22a and the unit support portion It is formed by abutting 22b.
  • each support part 22 is located in the front end side rather than each support part 21.
  • the housing 2 has a rail 25 that supports a rack 513 of a main body 51 (described later) of the plunger 5 so as to be movable in the longitudinal direction.
  • the rail 25 extends in the longitudinal direction of the housing 2.
  • the rack 513 moves along the rail 25 in the longitudinal direction of the housing 2, that is, in the longitudinal direction of the rack 513.
  • the housing 2 has a support portion 23 that supports the plunger 5 so as to be movable in the axial direction.
  • the support portion 23 includes a unit support portion 23a formed on the first housing member 2a and a unit support portion 23b formed on the second housing member 2b.
  • the support portion 23 is arranged in the longitudinal direction of the housing.
  • a through hole 231 is provided.
  • a main shaft portion 511 of a main body portion 51 described later of the plunger 5 is inserted into the hole 231, and the moving direction is restricted by an edge portion facing the hole 231 of the support portion 23, so that the plunger 5 has a longitudinal direction of the housing, That is, it can move only in the axial direction of the main shaft portion 511.
  • the housing 2 has an opening 28 at its base end.
  • the opening 28 is formed from the base end wall to the side wall of the housing.
  • a part of a later-described operation unit 31 of the rotating body 3 protrudes from the opening 28 to the outside.
  • the rotating body 3 includes an operation unit 31 and a drive gear 32, and is rotatably installed at the base end of the housing 2.
  • the operation unit 31 is a member to be rotated, and in the present embodiment, has a disk shape, that is, a relatively low columnar shape.
  • a plurality of grooves (not shown), that is, knurls, are formed on the outer peripheral surface of the operation unit 31 along the circumferential direction. Thereby, smoothness of the fingers and palms when the operation unit 31 is rotated with the fingers and palms can be prevented.
  • the rotating body 3 may be formed of an elastic material such as various rubber materials such as a constituent material of the gasket body 81 of the gasket 8 to be described later, various thermoplastic elastomers, and a mixture thereof. Without forming the plurality of grooves, it is possible to prevent a finger or palm from slipping when the operation unit 31 is rotated.
  • the operation unit 31 and the drive gear 32 are arranged concentrically, and the drive gear 32 is fixed to the side surface of the operation unit 31.
  • the operation portion 31 and the drive gear 32 are fixed to the shaft portion 33, and the shaft portion 33 is supported by the pair of bearings 21 of the housing 2 so as to be rotatable about the central axis with respect to the housing 2.
  • the drive gear 32 has a drive rotation shaft that coincides with the central axis of the shaft portion 33. Accordingly, when the operation unit 31 is rotated, the rotating body 3 is rotated, that is, the drive gear 32 is rotated around the drive rotation axis.
  • the operation unit 31 and the drive gear 32 may be separated from each other.
  • the drive gear 32 is accommodated in the housing 2, and a part of the operation portion 31 protrudes from the housing 2, and the remaining portion is accommodated in the housing 2.
  • a part of the operation part 31 protrudes outside from the opening 28 of the housing. That is, a part of the operation unit 31 protrudes outside from a side portion opposite to the rack 513 of the housing 2 across a later-described reduction rotation shaft that is a rotation shaft of the first gear 41, and further, Projects to the outside from the base end.
  • the operation part 31 can be operated easily. That is, since the operation part 31 protrudes outside from two places, the base end part and side part of the housing 2, it can be operated in any of the two places.
  • the distance from the drive rotation shaft to the outer peripheral surface of the operation unit 31, that is, the radius of the operation unit 31 is from the drive rotation shaft to a position where the drive gear 32 meshes with a first gear 41 described later of the gear assembly 4. Is greater than the pitch circle radius of the drive gear 32.
  • the radius of the operation unit 31 is preferably 2 to 10 times the pitch circle radius of the drive gear 32, and more preferably 3 to 5 times.
  • the drive rotation shaft is a fulcrum
  • the outer peripheral surface of the operation unit 31 is a power point
  • the position where the drive gear 32 meshes with a first gear 41 (to be described later) of the gear assembly 4 acts. It becomes a point.
  • the drive unit 32 can be rotated by rotating the operation unit 31 with a relatively small force. That is, the plunger 5 can be moved by rotating the operation unit 31 with a relatively small force, and the plunger 5 can be easily moved at a relatively low speed.
  • the pitch circle radius of a gear is the distance from the rotation axis (center) of the gear to the position where the gear meshes with another gear. That is, the pitch circle radius of the drive gear 32 is a distance from the drive rotation shaft (center of the drive gear 32) to a position where the drive gear 32 meshes with a first gear 41 (to be described later) of the gear assembly 4. .
  • the gear assembly 4 has a first gear 41 and a second gear 42, and is rotatably installed at the base end portion of the housing 2. Yes.
  • the gear assembly 4 is a reduction mechanism that reduces the rotational speed of the drive gear 32, amplifies the rotational force of the drive gear 32, and transmits it to a rack 513 (to be described later) of the plunger 5.
  • the first gear 41 and the second gear 42 are arranged concentrically, the first gear 41 meshes with the drive gear 32, and the second gear 42 is attached to a rack 513, which will be described later, of the plunger 5. It meshes and is fixed to the side surface of the first gear 41.
  • the first gears 41 and 42 are fixed to the shaft portion 43, and the shaft portion 43 is supported by the pair of bearings 22 of the housing 2 so as to be rotatable about the central axis with respect to the housing 2.
  • the first gear 41 has a reduction rotation shaft that coincides with the central axis of the shaft portion 43.
  • the first gear 41 and the second gear 42 rotate integrally around the same rotation axis, that is, the reduction rotation axis.
  • the first gear 41 is rotated by the rotation of the drive gear 32, and the rotational force associated with the rotation is transmitted from the second gear 42 to the rack 513.
  • the shaft portion 43 is installed so as to be parallel to the shaft portion 33.
  • the first gears 41 and 42 are housed in the housing 2, respectively. The first gears 41 and 42 may be separated from each other.
  • the pitch circle radius of the second gear 42 is smaller than the pitch circle radius of the first gear 41.
  • the pitch circle radius of the second gear 42 is preferably 1/4 to 2/3 of the pitch circle radius of the first gear 41, and more preferably 1/3 to 1/2.
  • the reduction rotation shaft is a fulcrum
  • the position where the first gear 41 meshes with the drive gear 32 is the power point
  • the second gear 42 meshes with the rack 513 of the plunger 5.
  • the position is the point of action.
  • the pitch circle radius of the second gear 42 is smaller than the pitch circle radius of the first gear 41, the rotational force of the second gear is amplified and transmitted to the rack 513.
  • the rotational speed of the drive gear 32 is reduced, and the rotational force of the drive gear 32 is transmitted to the rack 513 of the plunger 5. Can be moved.
  • the pitch circle radius of the first gear 41 is larger than the pitch circle radius of the drive gear 32.
  • the pitch circle radius of the first gear 41 is preferably 1.5 to 5 times, more preferably 2 to 3 times the pitch circle radius of the drive gear 32.
  • the plunger 5 is a member that presses a gasket 8, which will be described later, of the syringe 6 in the distal direction, that is, from a proximal end position in an outer cylinder 7 which will be described later toward the distal end position.
  • the plunger 5 includes a main body portion 51 and a pressing portion 52 that is provided at the distal end portion of the main body portion 51 and abuts against the gasket 8 during use and presses the gasket 8 in the distal end direction.
  • the main body 51 is connected to the main shaft portion 511 provided on the distal end side, the rack 513 provided on the proximal end side and meshing with the second gear 42 of the gear assembly 4, and the main shaft portion 511 and the rack 513.
  • the connection part 512 is comprised. Note that the axial direction of the main shaft portion 511 and the longitudinal direction of the rack 513 coincide.
  • the plunger 5 is installed in the housing 2 so that the axial direction of the main shaft portion 511 coincides with the longitudinal direction of the housing 2 and is movable in the axial direction of the main shaft portion 511. That is, first, the rack 513 of the plunger 5 is supported by the rail 25 of the housing 2 so as to be movable in the longitudinal direction.
  • the main shaft portion 511 of the plunger 5 is inserted into the hole 231 of the support portion 23 of the housing 2, and the movement direction is restricted by the edge portion facing the hole 231 of the support portion 23. It can move only in the direction, that is, the axial direction of the main shaft portion 511.
  • the plunger 5 is movable in the distal direction and the proximal direction.
  • the plunger 5 is not limited thereto, and may be installed to be movable only in the distal direction, for example.
  • the pressing portion 52 of the plunger 5 has a plate shape in the present embodiment, and the shape in plan view is a circular shape.
  • the pressing portion 52 is provided at the tip of the main shaft portion 511.
  • the pressing portion 52 In the initial state, that is, in the unused state, the pressing portion 52 is located at a position spaced apart from the core member 82 of the gasket 8 (described later) of the syringe 6 by a predetermined distance in the proximal direction (see FIGS. 1, 13, and 14). ). Thereby, when assembling the liquid administration tool 1, interference with the plunger 5 and the syringe 6 can be prevented, and it can assemble easily and reliably.
  • the position of the plunger 5 when not in use is referred to as an “initial position”.
  • the base end portion of the rack 513 contacts the base end wall of the housing 2, thereby preventing the plunger 5 from moving in the base end direction (see FIG. 14). Thereby, in the unused state, even if it is going to rotate the operation part 31 in the direction where the plunger 5 moves to a base end direction, the operation part 31 does not rotate.
  • the connecting portion 512 of the plunger 5 has an L shape in this embodiment.
  • the rack 513 is disposed at a position shifted from the axis of the plunger 5, that is, the axis of the main shaft portion 511.
  • the rotating body 3 and the gear assembly 4 can be disposed above the gasket 8, that is, in the space on the proximal end side of the gasket 8, whereby the liquid administration device 1 can be reduced in size.
  • Rotational motion of the second gear 42 is converted into linear motion of the rack 513 of the plunger 5. That is, the rotational force of the second gear 42 is transmitted to the rack 513 of the plunger 5, the plunger 5 moves in the distal direction, and the pressing portion 52 presses the gasket 8 of the syringe 6 in the distal direction. As a result, the gasket 8 moves in the distal direction in the outer cylinder 7.
  • the liquid administration device 1 when the rotating body 3, that is, the drive gear 32 is rotated such that a portion of the operation portion 31 that protrudes from the side portion of the housing 2 to the outside is moved in the distal direction.
  • the plunger 5 moves in the distal direction, and the gasket 8 moves in the distal direction.
  • the operation direction of the operation unit 31 and the movement direction of the plunger 5 coincide with each other, thereby enabling operation without a sense of incongruity.
  • the syringe 6 is provided with a bottom portion at the distal end portion and an opening portion at the proximal end portion, and is mounted on the outer cylinder 7 that can be filled with liquid, and the bottom portion of the outer cylinder 7.
  • a needle tube 9 having a sharp needle tip 91 at the distal end and a proximal end communicating with the outer cylinder 7, and moving from the proximal end position, which will be described later, to the distal end position along the axial direction of the outer cylinder 7 within the outer cylinder 7.
  • a gasket 8 to be obtained.
  • the outer cylinder 7 is composed of a bottomed cylindrical member having a bottom portion at the tip and an opening at the base end.
  • the side wall of the outer cylinder 7 has a cylindrical shape.
  • the outer diameter and the inner diameter of the bottom portion of the outer cylinder 7, that is, the distal end portion gradually decrease from the proximal end side toward the distal end side.
  • a needle tube 9 is attached to the central portion of the distal end portion of the outer cylinder 7.
  • tip part of the outer cylinder 7 comprises the discharge port which discharges
  • a plate-like flange 71 is integrally formed on the outer periphery of the base end of the outer cylinder 7.
  • a gasket 8 is accommodated (inserted) so as to be slidable (movable) along the axial direction of the outer cylinder 7.
  • the gasket 8 includes a gasket main body 81 made of an elastic material, and a core member 82 that is provided on the proximal end side of the gasket main body 81 and supports the gasket main body 81.
  • the base end of the core member 82 is located on the base end side with respect to the base end of the gasket body 81, and the pressing portion 52 of the plunger 5 comes into contact with the base end surface of the core member 82 in use. Yes.
  • a plurality (two in this embodiment) of ring-shaped protrusions 811 are formed on the entire outer periphery of the gasket body 81, and these protrusions 811 are in close contact with the inner peripheral surface of the outer cylinder 7. By sliding while sliding, the liquid-tightness can be more reliably maintained and the slidability can be improved.
  • the gasket body 81 is formed with a hollow portion that opens to the base end surface thereof, and the distal end portion of the core member 82 is fitted into the hollow portion, whereby the core member 82 supports the gasket body 81. .
  • the gasket body 81 and the core member 82 are not limited to the connection by fitting, for example, a structure connected by screwing or the like, a structure fixed by adhesion, fusion, or the like, or a structure in which the core member 82 is omitted. May be.
  • the space surrounded by the gasket 8 and the outer cylinder 7 is filled with a liquid in advance. Then, by moving the gasket 8 toward the distal end, that is, from the base end position in the outer cylinder 7 to the distal end position, the liquid in the outer cylinder 7 can be pushed out from the needle tube 9, that is, discharged.
  • the base end position of the gasket 8 is the position of the gasket 8 in the axial direction of the outer cylinder 7 in a state where the space surrounded by the gasket 8 and the outer cylinder 7 is filled with the liquid.
  • the tip position is the position of the gasket 8 in the axial direction of the outer cylinder 7 in a state where all of the filled liquid is discharged.
  • polyvinyl chloride polyethylene, polypropylene, cyclic polyolefin, Polystyrene such as polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, nylon) 6, various types of resins such as nylon 6,6, nylon 6,10, nylon 12).
  • polypropylene, cyclic polyolefin, polyester, poly- (4-methyl) are easy to mold.
  • pentene-1) Resin are easy to mold.
  • the material constituting the gasket body 81 is not particularly limited.
  • various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, Examples thereof include various thermoplastic elastomers such as polyamide, olefin, and styrene, or elastic materials such as a mixture thereof.
  • the needle tube 9 is attached to the center of the tip of the outer cylinder 7 and has a sharp needle tip 91 at the tip. A living body can be punctured with the needle tip 91. Further, the lumen (hollow part) of the needle tube 9 communicates with the outer cylinder 7 and functions as a flow path through which the liquid from the outer cylinder 7 passes. And in the state which punctured the biological body with the needle point 91, a liquid is inject
  • the constituent material of the needle tube 9 is not particularly limited.
  • the needle tube 9 is made of a metal material such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy.
  • a cap (not shown) is attached to the needle tube 9, and the needle tube 9 is covered with the cap.
  • the syringe 6 is mounted on the mounting portion 24 of the housing 2.
  • the flange 71 of the outer cylinder 7 is engaged with the engaging portions 241 and 242 of the mounting portion 24 from the proximal end side, and thereby the syringe 6 is prevented from being detached from the mounting portion 24.
  • the plunger 5 is installed on the second housing member 2 b of the housing 2.
  • the rack 513 of the plunger 5 is installed on the rail 25, and the main shaft portion 511 is inserted into the unit support portion 23 b that forms a part of the hole 231 of the support portion 23.
  • the gear assembly 4 is installed in the second housing member 2b.
  • the shaft portion 43 of the gear assembly 4 is installed on a pair of unit support portions 22 b constituting a part of the pair of bearings 22, and the second gear 42 is engaged with the rack 513.
  • the rotating body 3 is installed in the second housing member 2b.
  • the shaft portion 33 of the rotating body 3 is installed on a pair of unit support portions 21 b constituting a part of the pair of bearings 21, and the drive gear 32 is engaged with the first gear 41.
  • the syringe 6 is attached to the second housing member 2b.
  • the flange 71 of the outer cylinder 7 is engaged with the engaging portion 242 of the mounting portion 24 from the proximal end side.
  • the second housing member 2b and the first housing member 2a are joined.
  • the protrusions 27 of the second housing member 2b are fitted into the holes 26 of the first housing member 2a while aligning the second housing member 2b and the first housing member 2a.
  • the assembly of the liquid administration device 1 is completed.
  • an unused liquid administration device 1 is prepared, and a needle tube 9 of the liquid administration device 1 is punctured into a living body.
  • the operation unit 31 is rotated (turned) clockwise in FIG. 15 to administer the liquid in the outer cylinder 7 to the living body.
  • the operation of the operation unit 31 can be performed with a finger or a palm, for example.
  • the operation unit 31 by operating the operation unit 31 to rotate the drive gear 32, the rotation of the drive gear 32 is decelerated by the gear assembly 4, which is a reduction mechanism, and the rotational force of the drive gear 32 is applied to the plunger 5. Transmitted to the rack 513, the plunger 5 moves in the distal direction, and the pressing portion 52 of the plunger 5 comes into contact with the gasket 8.
  • the operation gear 31 When the operation gear 31 is further operated to further rotate the drive gear 32, the plunger 5 further moves in the distal direction, and the plunger 8 is pressed in the distal direction by the plunger 5 and moved in the distal direction.
  • the gasket 8 moves from the proximal end position in the outer cylinder 7 to the distal end position, whereby the liquid in the outer cylinder 7 is discharged from the needle tube 9 and administered to the living body.
  • the gear assembly 4 decelerates the rotation of the drive gear 32 and transmits the rotational force of the drive gear 32 to the rack 513 to move the plunger 5.
  • the force required for the operation of the operation unit 31 during the administration of the liquid can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably administered.
  • the gear assembly 4 decelerates the rotation of the drive gear 32 and transmits the rotational force of the drive gear 32 to the rack 513 to move the plunger 5, the liquid administration speed can be easily reduced. it can. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
  • the plunger 5 is moved by rotating the operation unit 31, for example, even a user who has difficulty with fingers and is difficult to press the plunger 5 directly uses the palm of his hand. By operating the operation unit 31, the liquid can be easily administered.
  • the operation unit 31 and the drive gear 32 are fixed to the shaft portion 33, and the shaft portion 33 is rotatably installed with respect to the housing 2.
  • the present invention is not limited to this.
  • 33 may be fixed to the housing 2, and the operation unit 31 and the drive gear 32 may be rotatably installed with respect to the shaft unit 33.
  • the first gears 41 and 42 are fixed to the shaft portion 43, and the shaft portion 43 is rotatably installed with respect to the housing 2.
  • the present invention is not limited to this.
  • 43 may be fixed to the housing 2, and the first gears 41 and 42 may be rotatably installed with respect to the shaft portion 43.
  • FIG. 19 is a cross-sectional view showing a second embodiment of the liquid administration device of the present invention.
  • the upper side in Fig. 19 is referred to as “base end (rear end)”
  • the lower side is referred to as “tip end”
  • the vertical direction is referred to as "axial direction” or “longitudinal direction.”
  • the part 31 and the ratchet 11 are side views.
  • the liquid administration device 1 includes a ratchet 11 including a gear 111 and a pawl 112 as a rotation direction restricting portion that restricts the rotation direction of the rotating body 3. .
  • the gear 111 of the ratchet 11 is fixed to the shaft portion 33 of the rotating body 3 and is disposed concentrically with the operation portion 31 and the drive gear 32. Further, the pawl 112 is fixed to the housing 2.
  • the teeth of the gear 111 are inclined counterclockwise in FIG. 19, and the pawl 112 is arranged on the left side of the gear 111 in FIG.
  • the ratchet 11 prevents the rotating body 3 from rotating counterclockwise in FIG. 19, and the rotating body 3 rotates only clockwise in FIG.
  • the ratchet 11 prevents the operation unit 31 from rotating counterclockwise in FIG. 19, thereby preventing the plunger 5 from moving in the proximal direction. it can. For this reason, for example, even when the plunger 5 and the gasket 8 are connected, it is possible to prevent the gasket 8 from moving in the proximal direction.
  • liquid administration device of the present invention has been described based on the illustrated embodiment, but the present invention is not limited to this, and the configuration of each part is replaced with an arbitrary configuration having the same function. can do. In addition, any other component may be added to the present invention.
  • the present invention may be a combination of any two or more configurations (features) of the above embodiments.
  • the liquid administration device of the above embodiment is a disposable type in which a syringe is previously mounted on the mounting portion of the housing.
  • the syringe is detachable from the mounting portion of the housing. You may be comprised so that it may mount
  • the syringe has no flange, the outer cylinder in which the discharge port at the tip is sealed with a rubber stopper, and both heads that support the outer cylinder and can be pierced with the rubber stopper of the outer cylinder at the tip.
  • a needle can be attached, and a holder having a threaded portion at the proximal end portion is provided, and the syringe can be detachably mounted on the housing mounted portion by the threaded portion of the holder.
  • the syringe is preliminarily filled with the liquid.
  • the present invention is not limited to this, and the syringe may be filled with the liquid later.
  • the syringe is included in the component of the liquid administration device.
  • the present invention is not limited to this, and the syringe may not be included in the component of the liquid administration device.
  • the operation unit has a disk shape.
  • the operation unit may have any shape as long as it forms a part of the rotating body. Examples of other shapes of the operation unit include a rod shape extending in the radial direction of the drive gear from the drive rotation shaft.
  • a plurality of protrusions protruding in the radial direction along the circumferential direction may be formed on the outer peripheral part of the disk-shaped operation part.
  • the protrusions are arranged at equiangular intervals.
  • the number of the protrusions may be one.
  • a notch may be formed in a part of the disk-shaped operation unit. In this case, it is preferable that the notch is located in the housing while the gasket moves from the proximal end position to the distal end position.
  • the operation unit may be constituted by the outer peripheral part of the drive gear, and the drive gear may be rotated by operating the outer peripheral part.
  • the drive gear may be rotated by operating the outer peripheral part.
  • at least a part of the drive gear protrudes from the housing to the outside.
  • the speed reduction mechanism is configured by the gear assembly 4 having the first gear 41 and the second gear 42.
  • the present invention is not limited to this.
  • One or more other gears may be interposed between the first gear and one or more other gears may be interposed between the second gear and the rack. Good.
  • the rotational force transmitted from the drive gear to the rack of the plunger is reduced, so that the drive gear and the first gear mesh with each other as in the above embodiment, and the second gear and It is preferable that the rack meshes.
  • the drive gear and the speed reduction mechanism may be composed of a worm gear.
  • the drive gear is a worm whose teeth are continuously cut in a spiral shape on a cylinder
  • the speed reduction mechanism is a worm wheel whose teeth are cut on the side surface of the disk in accordance with the worm.
  • the liquid administration device of the present invention is provided with a syringe having a discharge port provided at the tip, filled with a liquid, and having a cylindrical outer cylinder and a gasket slidably installed in the outer cylinder.
  • a liquid administration device for administering the liquid through the outlet A housing having a mounting portion to which the syringe is mounted at a tip portion;
  • a drive gear provided with a drive rotary shaft and installed in the housing so as to be rotatable around the drive rotary shaft, and at least a part of the drive gear protrudes from the housing and is operated to rotate the drive gear.
  • a rotating body having an operation unit;
  • a plunger having a rack, installed in the housing so as to be movable in a distal direction, and pressing the gasket in the distal direction;
  • a reduction mechanism that reduces the rotational speed of the drive gear and transmits the rotational force of the drive gear to the rack;
  • the plunger is moved while being decelerated by the deceleration mechanism, the force required for the liquid administration operation can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably obtained. Can be administered.
  • the liquid administration rate can be easily reduced. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
  • the plunger is moved by rotating the rotating body with the operation unit, for example, even a user who has difficulty with fingers and cannot easily press the plunger directly uses the palm of his hand. By operating the operation unit, the liquid can be easily administered.

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Abstract

A liquid administration device (1) comprises: a housing (2) having a mounting section (24) to which a syringe (6) is mounted; a rotatable body (3) having a drive gear (32) which is rotatably installed within the housing (2) and also having an operating section (31), a part of which protrudes to the outside from the housing (2) and which rotates the drive gear (32); a plunger (5) having a rack (513), the plunger (5) being installed within the housing (2) so as to be movable in the direction of the front end and pressing a gasket (8) in the direction of the front end; and a speed reduction mechanism for reducing the rotational speed of the drive gear (32) and transmitting the rotational force of the drive gear (32) to the rack (513). Operating the operating section (31) and rotating the drive gear (32) while the syringe (6) is mounted to the mounting section (24) causes the reduction mechanism to reduce the rotational speed of the drive gear (32), the rotational force of the drive gear (32) is transmitted to the rack (513), the plunger (5) is moved in the direction of the front end, and the gasket (8) of the syringe (6) moves in the direction of the front end by being pressed in the direction of the front end by the plunger (5).

Description

液体投与具Liquid dosing device
　本発明は、液体投与具に関するものである。 The present invention relates to a liquid administration device.
　従来から、無菌的に薬液が充填され、その薬液を投与可能なプレフィルドシリンジが知られている（例えば、特許文献１参照）。 Conventionally, a prefilled syringe that is filled with a chemical solution aseptically and that can administer the chemical solution is known (for example, see Patent Document 1).
　プレフィルドシリンジは、薬液が吐出する口部を有するシリンジ外筒と、シリンジ外筒の口部に設けられ、先端に鋭利な針先を有する針管と、シリンジ外筒内で摺動し得るガスケットと、シリンジ外筒とガスケットとで囲まれた空間に充填された薬液と、ガスケットの基端側に連結され、該ガスケットを先端方向に向かって押圧して薬液を口部から吐出させるプランジャとを備えている。プレフィルドシリンジを用いて薬液を投与する際には、針管を生体に穿刺し、この穿刺状態のまま、プランジャを押圧操作する。これにより、ガスケットで薬液が口部から吐出することとなり、よって、当該薬液を針管を介して生体に投与することができる。 The prefilled syringe is a syringe outer cylinder having a mouth part for discharging a chemical solution, a needle tube provided at the mouth part of the syringe outer cylinder and having a sharp needle tip at the tip, a gasket capable of sliding in the syringe outer cylinder, A drug solution filled in a space surrounded by the syringe outer cylinder and the gasket, and a plunger connected to the proximal end side of the gasket and pressing the gasket toward the distal end to discharge the drug solution from the mouth. Yes. When administering a drug solution using a prefilled syringe, the needle tube is punctured into the living body, and the plunger is pressed in this punctured state. Thereby, a chemical | medical solution will be discharged from a mouth part with a gasket, Therefore The said chemical | medical solution can be administered to a biological body via a needle tube.
　しかしながら、このような従来のプレフィルドシリンジでは、例えば、高粘度の薬液を投与する場合、プランジャを押圧操作する際、押圧抵抗が高く、その押圧操作をし難いという問題がある。 However, with such a conventional prefilled syringe, for example, when a high-viscosity chemical solution is administered, there is a problem that when the plunger is pressed, the pressing resistance is high and the pressing operation is difficult.
　また、薬液によっては、その投与速度を遅くする必要があるものがあり、その場合は、プランジャをゆっくりと移動させる必要があるが、プランジャをゆっくりと移動させることは困難である。 Also, some chemical solutions require that the administration rate be slow, and in that case, it is necessary to move the plunger slowly, but it is difficult to move the plunger slowly.
　また、手指が不自由な使用者の場合は、その手指でプランジャを押圧操作することが困難である。 Also, in the case of a user who has difficulty with fingers, it is difficult to press the plunger with the fingers.
特開２００４－９７６４０号公報JP 2004-97640 A
　本発明の目的は、液体の投与に必要な力を小さくし、また、容易に液体の投与速度を遅くすることができ、また、プランジャを押圧操作することが困難な使用者でも容易に液体を投与することができる液体投与具を提供することにある。 The object of the present invention is to reduce the force required for liquid administration, to easily reduce the liquid administration speed, and to easily apply liquid to a user who is difficult to press the plunger. The object is to provide a liquid administration device that can be administered.
　このような目的は、下記の本発明により達成される。 Such an object is achieved by the present invention described below.
　本発明は、先端部に排出口が設けられ、液体が充填され、筒状をなす外筒と、前記外筒内を摺動可能に設置されたガスケットとを有するシリンジを装着し、前記排出口を介して前記液体を投与する液体投与具であって、
　先端部に前記シリンジが装着される装着部を有するハウジングと、
　駆動回転軸を具備し、前記ハウジング内に前記駆動回転軸を中心に回動可能に設置された駆動歯車と、少なくとも一部が前記ハウジングから外部に突出し、操作して前記駆動歯車を回動させる操作部とを有する回転体と、
　ラックを有し、前記ハウジング内に先端方向に移動可能に設置され、前記ガスケットを先端方向に押圧するプランジャと、
　前記駆動歯車の回転速度を減速し、該駆動歯車の回転力を前記ラックに伝達する減速機構とを備え、
　前記装着部に前記シリンジが装着された装着状態で、前記操作部を操作して前記駆動歯車を回動させることにより、前記減速機構により、前記駆動歯車の回転速度が減速され、該駆動歯車の回転力が前記ラックに伝達され、前記プランジャが先端方向に移動し、該プランジャにより、前記ガスケットが先端方向に押圧されて先端方向に移動するよう構成されていることを特徴とする液体投与具である。 The present invention is provided with a syringe having a discharge port provided at a tip end, filled with a liquid and having a cylindrical shape, and a gasket slidably installed in the outer tube, and the discharge port A liquid administration device for administering the liquid via
A housing having a mounting portion to which the syringe is mounted at a tip portion;
A drive gear provided with a drive rotary shaft and installed in the housing so as to be rotatable around the drive rotary shaft, and at least a part of the drive gear protrudes from the housing and is operated to rotate the drive gear. A rotating body having an operation unit;
A plunger having a rack, installed in the housing so as to be movable in a distal direction, and pressing the gasket in the distal direction;
A reduction mechanism that reduces the rotational speed of the drive gear and transmits the rotational force of the drive gear to the rack;
By rotating the drive gear by operating the operation unit in a mounted state in which the syringe is mounted on the mounting unit, the rotational speed of the drive gear is reduced by the reduction mechanism, and the drive gear A liquid administration device, wherein a rotational force is transmitted to the rack, the plunger moves in a distal direction, and the plunger pushes the gasket in the distal direction to move in the distal direction. is there.
　本発明の液体投与具では、前記減速機構は、前記ハウジング内に回動可能に設置され、減速回転軸を具備し、前記駆動歯車の回動によって前記減速回転軸を中心に回動する第１の歯車と、前記第１の歯車よりもピッチ円半径が小さく、前記減速回転軸を中心に前記第１の歯車と一体的に回動し、その回動に伴う回転力が前記ラックに伝達される第２の歯車とを有する歯車組立体を備えることが好ましい。 In the liquid administration device of the present invention, the speed reduction mechanism is rotatably installed in the housing, includes a speed reduction rotation shaft, and rotates about the speed reduction rotation shaft by rotation of the drive gear. The gear wheel has a smaller pitch circle radius than the first gear, and rotates integrally with the first gear about the reduction rotation shaft, and the rotational force associated with the rotation is transmitted to the rack. It is preferable to provide a gear assembly having a second gear.
　本発明の液体投与具では、前記第１の歯車のピッチ円半径は、前記駆動歯車のピッチ円半径よりも大きいことが好ましい。 In the liquid administration device of the present invention, the pitch circle radius of the first gear is preferably larger than the pitch circle radius of the drive gear.
　本発明の液体投与具では、前記ハウジングの前記ラックに対して、前記減速回転軸を挟んだ反対側の側部から、前記操作部の一部が外部に突出していることが好ましい。 In the liquid administration device of the present invention, it is preferable that a part of the operation portion protrudes to the outside from a side portion on the opposite side of the rack of the housing with the reduction rotation shaft interposed therebetween.
　本発明の液体投与具では、前記操作部の前記ハウジングの前記側部から外部に突出している部位を先端方向に移動させるようにして前記駆動歯車を回転させると、前記プランジャが先端方向に移動するよう構成されていることが好ましい。 In the liquid administration device of the present invention, when the drive gear is rotated so as to move the portion of the operation portion that protrudes from the side portion of the housing to the distal direction, the plunger moves in the distal direction. It is preferable that it is comprised.
　本発明の液体投与具では、前記操作部は、前記ハウジングの基端部に配置されており、前記操作部の一部が前記ハウジングの基端部から外部に突出していることが好ましい。 In the liquid administration device of the present invention, it is preferable that the operation portion is disposed at a base end portion of the housing, and a part of the operation portion protrudes outside from the base end portion of the housing.
　本発明の液体投与具では、前記駆動回転軸から、前記操作部を操作する際の該操作部における力点までの距離が、前記駆動歯車のピッチ円半径よりも長いことが好ましい。 In the liquid administration device of the present invention, it is preferable that the distance from the drive rotation shaft to the power point in the operation unit when operating the operation unit is longer than the pitch circle radius of the drive gear.
　本発明の液体投与具では、前記操作部は、円盤状をなしていることが好ましい。 In the liquid administration device of the present invention, it is preferable that the operation unit has a disk shape.
　本発明の液体投与具では、前記装着部に装着され、予め前記液体が充填された前記シリンジを有することが好ましい。 In the liquid administration device of the present invention, it is preferable to have the syringe that is attached to the attachment portion and filled with the liquid in advance.
　本発明によれば、減速機構により減速してプランジャを移動するので、液体の投与の操作に必要な力を小さくすることができ、これにより、比較的粘度の高い液体でも容易かつ確実にその液体を投与することができる。 According to the present invention, since the plunger is moved while being decelerated by the deceleration mechanism, the force required for the liquid administration operation can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably obtained. Can be administered.
　また、容易に、液体の投与速度を遅くすることができる。これにより、投与速度を遅くする必要がある液体を容易かつ確実に投与することができ、また、液体の投与の際の痛みを低減することができ、また、液体の漏出等を防止することができる。 Also, the liquid administration rate can be easily reduced. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
　また、プランジャの移動は、操作部により回転体を回動操作することによりなされるので、例えば、手指が不自由で、プランジャを直接押圧操作することが困難な使用者でも、手の平等を使用して操作部を操作し、容易に液体を投与することができる。 In addition, since the plunger is moved by rotating the rotating body with the operation unit, for example, even a user who has difficulty with fingers and cannot easily press the plunger directly uses the palm of his hand. By operating the operation unit, the liquid can be easily administered.
図１は、本発明の液体投与具の第１実施形態を示す斜視図である。FIG. 1 is a perspective view showing a first embodiment of the liquid administration device of the present invention. 図２は、図１に示す液体投与具の断面図である。FIG. 2 is a cross-sectional view of the liquid administration device shown in FIG. 図３は、図１に示す液体投与具のハウジングの第１のハウジング部材の断面図である。FIG. 3 is a sectional view of a first housing member of the housing of the liquid administration device shown in FIG. 図４は、図１に示す液体投与具のハウジングの第２のハウジング部材の断面図である。4 is a cross-sectional view of a second housing member of the housing of the liquid administration device shown in FIG. 図５は、図１に示す液体投与具の回転体の斜視図である。FIG. 5 is a perspective view of a rotating body of the liquid administration device shown in FIG. 図６は、図１に示す液体投与具の歯車組立体の斜視図である。FIG. 6 is a perspective view of the gear assembly of the liquid administration device shown in FIG. 図７は、図１に示す液体投与具のプランジャの斜視図である。FIG. 7 is a perspective view of a plunger of the liquid administration device shown in FIG. 図８は、図１に示す液体投与具のシリンジの外筒および針管の斜視図である。FIG. 8 is a perspective view of the outer cylinder and needle tube of the syringe of the liquid administration device shown in FIG. 図９は、図１に示す液体投与具の組み立て手順を説明するための斜視図である。FIG. 9 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG. 図１０は、図１に示す液体投与具の組み立て手順を説明するための斜視図である。FIG. 10 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG. 図１１は、図１に示す液体投与具の組み立て手順を説明するための斜視図である。FIG. 11 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG. 1. 図１２は、図１に示す液体投与具の組み立て手順を説明するための斜視図である。FIG. 12 is a perspective view for explaining an assembly procedure of the liquid administration device shown in FIG. 図１３は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 13 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG. 図１４は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 14 is a cross-sectional view for explaining the operation when using the liquid administration device shown in FIG. 図１５は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 15 is a cross-sectional view for explaining an operation when the liquid administration device shown in FIG. 1 is used. 図１６は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 16 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG. 図１７は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 17 is a cross-sectional view for explaining the operation when using the liquid administration device shown in FIG. 図１８は、図１に示す液体投与具の使用の際の動作を説明するための断面図である。FIG. 18 is a cross-sectional view for explaining the operation in using the liquid administration device shown in FIG. 図１９は、本発明の液体投与具の第２実施形態を示す断面図である。FIG. 19 is a cross-sectional view showing a second embodiment of the liquid administration device of the present invention.
　以下、本発明の液体投与具を添付図面に示す好適な実施形態に基づいて詳細に説明する。 Hereinafter, the liquid administration device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
　＜第１実施形態＞
　図１は、本発明の液体投与具の第１実施形態を示す斜視図である。図２は、図１に示す液体投与具の断面図である。図３は、図１に示す液体投与具のハウジングの第１のハウジング部材の断面図である。図４は、図１に示す液体投与具のハウジングの第２のハウジング部材の断面図である。図５は、図１に示す液体投与具の回転体の斜視図である。図６は、図１に示す液体投与具の歯車組立体の斜視図である。図７は、図１に示す液体投与具のプランジャの斜視図である。図８は、図１に示す液体投与具のシリンジの外筒および針管の斜視図である。図９～図１２は、それぞれ、図１に示す液体投与具の組み立て手順を説明するための斜視図である。図１３～図１８は、それぞれ、図１に示す液体投与具の使用の際の動作を説明するための断面図である。 <First Embodiment>
FIG. 1 is a perspective view showing a first embodiment of the liquid administration device of the present invention. FIG. 2 is a cross-sectional view of the liquid administration device shown in FIG. FIG. 3 is a sectional view of a first housing member of the housing of the liquid administration device shown in FIG. 4 is a cross-sectional view of a second housing member of the housing of the liquid administration device shown in FIG. FIG. 5 is a perspective view of a rotating body of the liquid administration device shown in FIG. FIG. 6 is a perspective view of the gear assembly of the liquid administration device shown in FIG. FIG. 7 is a perspective view of a plunger of the liquid administration device shown in FIG. FIG. 8 is a perspective view of the outer cylinder and needle tube of the syringe of the liquid administration device shown in FIG. 9 to 12 are perspective views for explaining the procedure for assembling the liquid administration device shown in FIG. 13 to 18 are cross-sectional views for explaining the operation when using the liquid administration device shown in FIG.
　なお、以下では、図１～図４、図７～図１８中の上側を「基端（後端）」、下側を「先端」、上下方向を「軸方向」または「長手方向として説明を行う。 In the following description, the upper side in FIGS. 1 to 4 and 7 to 18 is referred to as “base end (rear end)”, the lower side is referred to as “tip”, and the vertical direction is referred to as “axial direction” or “longitudinal direction”. Do.
　図１～図１８に示す液体投与具１は、液体を生体に投与する（注入する）際に用いられる医療器具である。なお、液体としては、その使用目的に応じて適宜選択されるが、例えば、抗体等の蛋白質性医薬品、低分子蛋白質、ホルモン等のペプチド性医薬品、核酸医薬品、細胞医薬品、血液製剤、各種感染症を予防するワクチン、抗がん剤、麻酔薬、麻薬、抗生物質、ステロイド剤、蛋白質分解酵素阻害剤等、主に皮下注射される薬液が挙げられる。 A liquid administration device 1 shown in FIGS. 1 to 18 is a medical instrument used when a liquid is administered (injected) into a living body. The liquid is appropriately selected according to the purpose of use. For example, protein drugs such as antibodies, peptide drugs such as low molecular weight proteins and hormones, nucleic acid drugs, cell drugs, blood products, various infectious diseases Examples include vaccines, anticancer agents, anesthetics, narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, etc. that are mainly injected subcutaneously.
　図１、図２および図１２に示すように、液体投与具１は、回転体３と、減速機構である歯車組立体４と、プランジャ５と、シリンジ６と、これらを収納するハウジング２とを備えている。 As shown in FIGS. 1, 2, and 12, the liquid administration device 1 includes a rotating body 3, a gear assembly 4 that is a speed reduction mechanism, a plunger 5, a syringe 6, and a housing 2 that houses them. I have.
　図１～図４に示すように、ハウジング２は、図１中の上下方向に長い箱状をなしており、その先端に開口が形成されている。また、ハウジング２は、本実施形態では２つの部材、すなわち、互いに接合された第１のハウジング部材２ａと、第２のハウジング部材２ｂとで構成されている。この場合、第１のハウジング部材２ａの先端部の壁部には、４つの孔２６が形成されており、第２のハウジング部材２ｂの先端部の内面には、その４つの孔２６に嵌入する４つの突出部２７が形成されている。そして、各突出部２７がそれぞれ各孔２６に嵌入することにより、第１のハウジング部材２ａと、第２のハウジング部材２ｂとが接合されている。 As shown in FIGS. 1 to 4, the housing 2 has a long box shape in the vertical direction in FIG. 1, and an opening is formed at the tip thereof. In the present embodiment, the housing 2 includes two members, that is, a first housing member 2a and a second housing member 2b joined to each other. In this case, four holes 26 are formed in the wall portion of the distal end portion of the first housing member 2a, and the inner surface of the distal end portion of the second housing member 2b is fitted into the four holes 26. Four protrusions 27 are formed. And each 1st housing member 2a and 2nd housing member 2b are joined because each protrusion part 27 fits in each hole 26, respectively.
　なお、第１のハウジング部材２ａと、第２のハウジング部材２ｂとの接合方法は、これに限らず、例えば、熱融着、高周波融着、超音波融着等の融着または接着剤や溶剤等による接着等が挙げられる。 In addition, the joining method of the 1st housing member 2a and the 2nd housing member 2b is not restricted to this, For example, fusion, such as heat fusion, high frequency fusion, ultrasonic fusion, or an adhesive agent or solvent For example, adhesion by the like.
　また、ハウジング２は、その先端部に、シリンジ６が装着される装着部２４を有している。装着部２４にシリンジ６が装着された装着状態では、ハウジング２の長手方向とシリンジ６の後述する外筒７の軸方向とが一致し、シリンジ６の後述する針管９の少なくとも先端部は、ハウジング２の先端から先端方向に向って外部に突出している。なお、本実施形態では、針管９の全体が外部に突出しているが、これに限らず、例えば、針管９の先端部のみが外部に突出していてもよい。 Further, the housing 2 has a mounting portion 24 to which the syringe 6 is mounted at the tip thereof. In the mounted state in which the syringe 6 is mounted on the mounting portion 24, the longitudinal direction of the housing 2 and the axial direction of the outer cylinder 7 described later of the syringe 6 coincide with each other, and at least the distal end portion of the needle tube 9 described later of the syringe 6 It protrudes outside from the front-end | tip of 2 toward the front-end | tip direction. In the present embodiment, the entire needle tube 9 protrudes to the outside. However, the present invention is not limited to this. For example, only the distal end portion of the needle tube 9 may protrude to the outside.
　装着部２４は、その装着部２４にシリンジ６が装着された装着状態で、シリンジ６の後述する外筒７のフランジ７１が係合する係合部２４１、２４２を有している。係合部２４１は、第１のハウジング部材２ａの内面に形成されたリブであり、係合部２４２は、第２のハウジング部材２ｂの内面に形成されたリブである。そして、各係合部２４１、２４２は、所定距離離間し、互いに対向するように配置されている。この係合部２４１、２４２により、シリンジ６が装着部２４から離脱してしまうことを防止することができる。 The mounting portion 24 has engaging portions 241 and 242 that engage with a flange 71 of an outer cylinder 7 (described later) of the syringe 6 in a mounting state in which the syringe 6 is mounted on the mounting portion 24. The engaging portion 241 is a rib formed on the inner surface of the first housing member 2a, and the engaging portion 242 is a rib formed on the inner surface of the second housing member 2b. The engaging portions 241 and 242 are arranged so as to face each other with a predetermined distance therebetween. The engagement portions 241 and 242 can prevent the syringe 6 from being detached from the mounting portion 24.
　また、ハウジング２は、その基端部に、回転体３の後述する軸部３３を回動自在に支持する１対の軸受け２１と、歯車組立体４の後述する軸部４３を回動自在に支持する１対の軸受け２２とを有している。これらの軸受け２１、２２は、それぞれ、軸部３３と軸部４３とが平行になるように設けられている。 In addition, the housing 2 has a pair of bearings 21 that rotatably support a shaft portion 33 (described later) of the rotating body 3 and a shaft portion 43 (described later) of the gear assembly 4 at the base end portion thereof. It has a pair of bearings 22 to support. These bearings 21 and 22 are provided such that the shaft portion 33 and the shaft portion 43 are parallel to each other.
　そして、各軸受け２１は、ハウジング２の基端部に、所定距離離間し、互いに対向するように配置されている。各軸受け２１は、それぞれ、第１のハウジング部材２ａに形成された単位支持部２１ａと、第２のハウジング部材２ｂに形成された単位支持部２１ｂとで構成され、単位支持部２１ａと単位支持部２１ｂとを突き合わせることにより形成されている。 The bearings 21 are arranged at the base end of the housing 2 so as to be separated from each other by a predetermined distance and to face each other. Each bearing 21 includes a unit support portion 21a formed on the first housing member 2a and a unit support portion 21b formed on the second housing member 2b. The unit support portion 21a and the unit support portion It is formed by abutting 21b.
　また、各軸受け２２は、ハウジング２の基端部に、所定距離離間し、互いに対向するように配置されている。各軸受け２２は、それぞれ、第１のハウジング部材２ａに形成された単位支持部２２ａと、第２のハウジング部材２ｂに形成された単位支持部２２ｂとで構成され、単位支持部２２ａと単位支持部２２ｂとを突き合わせることにより形成されている。なお、各支持部２２は、各支持部２１よりも先端側に位置している。 Further, the bearings 22 are arranged at the base end portion of the housing 2 so as to be separated from each other by a predetermined distance and to face each other. Each bearing 22 includes a unit support portion 22a formed on the first housing member 2a and a unit support portion 22b formed on the second housing member 2b. The unit support portion 22a and the unit support portion It is formed by abutting 22b. In addition, each support part 22 is located in the front end side rather than each support part 21. FIG.
　また、ハウジング２は、プランジャ５の後述する本体部５１のラック５１３をその長手方向に移動可能に支持するレール２５を有している。レール２５は、ハウジング２の長手方向に延在している。ラック５１３は、そのレール２５に沿って、ハウジング２の長手方向、すなわちラック５１３の長手方向に移動する。 Further, the housing 2 has a rail 25 that supports a rack 513 of a main body 51 (described later) of the plunger 5 so as to be movable in the longitudinal direction. The rail 25 extends in the longitudinal direction of the housing 2. The rack 513 moves along the rail 25 in the longitudinal direction of the housing 2, that is, in the longitudinal direction of the rack 513.
　また、ハウジング２は、プランジャ５をその軸方向に移動可能に支持する支持部２３を有している。この支持部２３は、第１のハウジング部材２ａに形成された単位支持部２３ａと、第２のハウジング部材２ｂに形成された単位支持部２３ｂとで構成され、支持部２３をハウジングの長手方向に貫通する孔２３１を有している。プランジャ５の後述する本体部５１の主軸部５１１は、その孔２３１に挿入され、支持部２３の孔２３１に臨む縁部により移動方向が規制され、これにより、プランジャ５は、ハウジングの長手方向、すなわち主軸部５１１の軸方向のみに移動可能になっている。 The housing 2 has a support portion 23 that supports the plunger 5 so as to be movable in the axial direction. The support portion 23 includes a unit support portion 23a formed on the first housing member 2a and a unit support portion 23b formed on the second housing member 2b. The support portion 23 is arranged in the longitudinal direction of the housing. A through hole 231 is provided. A main shaft portion 511 of a main body portion 51 described later of the plunger 5 is inserted into the hole 231, and the moving direction is restricted by an edge portion facing the hole 231 of the support portion 23, so that the plunger 5 has a longitudinal direction of the housing, That is, it can move only in the axial direction of the main shaft portion 511.
　また、ハウジング２は、その基端部に開口２８を有している。この開口２８は、ハウジングの基端壁から側壁に亘って形成されている。回転体３の後述する操作部３１の一部は、この開口２８から外部に突出している。 Further, the housing 2 has an opening 28 at its base end. The opening 28 is formed from the base end wall to the side wall of the housing. A part of a later-described operation unit 31 of the rotating body 3 protrudes from the opening 28 to the outside.
　図１、図２、図５および図１２に示すように、回転体３は、操作部３１と、駆動歯車３２とを有し、ハウジング２の基端部に回動自在に設置されている。 As shown in FIGS. 1, 2, 5, and 12, the rotating body 3 includes an operation unit 31 and a drive gear 32, and is rotatably installed at the base end of the housing 2.
　操作部３１は、回動操作される部材であり、本実施形態では、円盤状、すなわち、比較的高さの低い円柱状をなしている。そして、操作部３１の外周面には、その周方向に沿って、図示しない複数の溝、すなわちローレットが形成されている。これにより、操作部３１を手指や手の平で回動操作したときの手指や手の平の平滑りを防止することができる。 The operation unit 31 is a member to be rotated, and in the present embodiment, has a disk shape, that is, a relatively low columnar shape. A plurality of grooves (not shown), that is, knurls, are formed on the outer peripheral surface of the operation unit 31 along the circumferential direction. Thereby, smoothness of the fingers and palms when the operation unit 31 is rotated with the fingers and palms can be prevented.
　なお、回転体３を、例えば、後述するガスケット８のガスケット本体８１の構成材料のような各種ゴム材料、各種熱可塑性エラストマー、それらの混合物等の弾性材料で形成してもよく、この場合は、前記複数の溝を形成することなく、操作部３１を回動操作したときの手指や手の平の滑りを防止することができる。 The rotating body 3 may be formed of an elastic material such as various rubber materials such as a constituent material of the gasket body 81 of the gasket 8 to be described later, various thermoplastic elastomers, and a mixture thereof. Without forming the plurality of grooves, it is possible to prevent a finger or palm from slipping when the operation unit 31 is rotated.
　操作部３１と駆動歯車３２とは、同心的に配置され、駆動歯車３２は、操作部３１の側面に固定されている。そして、操作部３１および駆動歯車３２は、軸部３３に固定され、軸部３３は、ハウジング２の１対の軸受け２１に、ハウジング２に対して、その中心軸を中心に回動自在に支持されている。また、駆動歯車３２は、軸部３３の中心軸と一致する駆動回転軸を有している。これにより、操作部３１を回動操作すると、回転体３が回動、すなわち、駆動歯車３２が駆動回転軸を中心に回動する。なお、操作部３１および駆動歯車３２は、互いに離間していてもよい。 The operation unit 31 and the drive gear 32 are arranged concentrically, and the drive gear 32 is fixed to the side surface of the operation unit 31. The operation portion 31 and the drive gear 32 are fixed to the shaft portion 33, and the shaft portion 33 is supported by the pair of bearings 21 of the housing 2 so as to be rotatable about the central axis with respect to the housing 2. Has been. Further, the drive gear 32 has a drive rotation shaft that coincides with the central axis of the shaft portion 33. Accordingly, when the operation unit 31 is rotated, the rotating body 3 is rotated, that is, the drive gear 32 is rotated around the drive rotation axis. The operation unit 31 and the drive gear 32 may be separated from each other.
　また、駆動歯車３２は、ハウジング２内に収納されており、操作部３１は、その一部がハウジング２から外部に突出し、残部は、ハウジング２内に収納されている。この場合、操作部３１の一部は、ハウジングの開口２８から外部に突出している。すなわち、操作部３１の一部は、第１の歯車４１の回転軸である後述する減速回転軸を挟んで、ハウジング２のラック５１３と反対側の側部から外部に突出し、さらに、ハウジング２の基端部から外部に突出している。これにより、操作部３１を容易に操作することができる。すなわち、操作部３１は、ハウジング２の基端部と側部との２箇所から外部に突出しているので、その２箇所のいずれにおいても操作することができる。 Further, the drive gear 32 is accommodated in the housing 2, and a part of the operation portion 31 protrudes from the housing 2, and the remaining portion is accommodated in the housing 2. In this case, a part of the operation part 31 protrudes outside from the opening 28 of the housing. That is, a part of the operation unit 31 protrudes outside from a side portion opposite to the rack 513 of the housing 2 across a later-described reduction rotation shaft that is a rotation shaft of the first gear 41, and further, Projects to the outside from the base end. Thereby, the operation part 31 can be operated easily. That is, since the operation part 31 protrudes outside from two places, the base end part and side part of the housing 2, it can be operated in any of the two places.
　また、駆動回転軸から操作部３１の外周面までの距離、すなわち、操作部３１の半径は、駆動回転軸から駆動歯車３２が歯車組立体４の後述する第１の歯車４１と噛合する位置までの距離、すなわち駆動歯車３２のピッチ円半径よりも大きい。この場合、操作部３１の半径は、駆動歯車３２のピッチ円半径の２～１０倍であることが好ましく、３～５倍であることがより好ましい。ここで、操作部３１を回動操作する際、駆動回転軸が支点、操作部３１の外周面が力点、駆動歯車３２が歯車組立体４の後述する第１の歯車４１と噛合する位置が作用点となる。したがって、操作部３１の半径が駆動歯車３２のピッチ円半径よりも大きいことにより、比較的小さい力で、操作部３１を回動操作して、駆動歯車３２を回動させることができる。すなわち、比較的小さい力で、操作部３１を回動操作して、プランジャ５を移動させることができ、また、比較的遅い速度で、容易に、プランジャ５を移動させることができる。 Further, the distance from the drive rotation shaft to the outer peripheral surface of the operation unit 31, that is, the radius of the operation unit 31 is from the drive rotation shaft to a position where the drive gear 32 meshes with a first gear 41 described later of the gear assembly 4. Is greater than the pitch circle radius of the drive gear 32. In this case, the radius of the operation unit 31 is preferably 2 to 10 times the pitch circle radius of the drive gear 32, and more preferably 3 to 5 times. Here, when the operation unit 31 is rotated, the drive rotation shaft is a fulcrum, the outer peripheral surface of the operation unit 31 is a power point, and the position where the drive gear 32 meshes with a first gear 41 (to be described later) of the gear assembly 4 acts. It becomes a point. Therefore, since the radius of the operation unit 31 is larger than the pitch circle radius of the drive gear 32, the drive unit 32 can be rotated by rotating the operation unit 31 with a relatively small force. That is, the plunger 5 can be moved by rotating the operation unit 31 with a relatively small force, and the plunger 5 can be easily moved at a relatively low speed.
　なお、歯車のピッチ円半径とは、その歯車の回転軸（中心）から、その歯車が他の歯車と噛合する位置までの距離である。すなわち、駆動歯車３２のピッチ円半径とは、駆動回転軸（駆動歯車３２の中心）から、その駆動歯車３２が歯車組立体４の後述する第１の歯車４１と噛合する位置までの距離である。 The pitch circle radius of a gear is the distance from the rotation axis (center) of the gear to the position where the gear meshes with another gear. That is, the pitch circle radius of the drive gear 32 is a distance from the drive rotation shaft (center of the drive gear 32) to a position where the drive gear 32 meshes with a first gear 41 (to be described later) of the gear assembly 4. .
　図１、図６および図１２に示すように、歯車組立体４は、第１の歯車４１と、第２の歯車４２とを有し、ハウジング２の基端部に回動自在に設置されている。この歯車組立体４は、駆動歯車３２の回転速度を減速し、その駆動歯車３２の回転力を増幅してプランジャ５の後述するラック５１３に伝達する減速機構である。 As shown in FIGS. 1, 6, and 12, the gear assembly 4 has a first gear 41 and a second gear 42, and is rotatably installed at the base end portion of the housing 2. Yes. The gear assembly 4 is a reduction mechanism that reduces the rotational speed of the drive gear 32, amplifies the rotational force of the drive gear 32, and transmits it to a rack 513 (to be described later) of the plunger 5.
　第１の歯車４１と第２の歯車４２とは同心的に配置され、第１の歯車４１は、駆動歯車３２と噛合し、また、第２の歯車４２は、プランジャ５の後述するラック５１３に噛合し、第１の歯車４１の側面に固定されている。そして、第１の歯車４１および４２は、軸部４３に固定され、軸部４３は、ハウジング２の１対の軸受け２２に、ハウジング２に対して、その中心軸を中心に回動自在に支持されている。また、第１の歯車４１は、軸部４３の中心軸と一致する減速回転軸を有している。これにより、第１の歯車４１と第２の歯車４２とは同一の回転軸、すなわち、減速回転軸を中心に一体的に回動する。なお、第１の歯車４１は、駆動歯車３２の回動によって回動し、第２の歯車４２からは、その回動に伴う回転力がラック５１３に伝達される。 The first gear 41 and the second gear 42 are arranged concentrically, the first gear 41 meshes with the drive gear 32, and the second gear 42 is attached to a rack 513, which will be described later, of the plunger 5. It meshes and is fixed to the side surface of the first gear 41. The first gears 41 and 42 are fixed to the shaft portion 43, and the shaft portion 43 is supported by the pair of bearings 22 of the housing 2 so as to be rotatable about the central axis with respect to the housing 2. Has been. Further, the first gear 41 has a reduction rotation shaft that coincides with the central axis of the shaft portion 43. As a result, the first gear 41 and the second gear 42 rotate integrally around the same rotation axis, that is, the reduction rotation axis. The first gear 41 is rotated by the rotation of the drive gear 32, and the rotational force associated with the rotation is transmitted from the second gear 42 to the rack 513.
　また、軸部４３は、軸部３３と平行になるように設置されている。また、第１の歯車４１および４２は、それぞれ、ハウジング２内に収納されている。なお、第１の歯車４１および４２は、互いに離間していてもよい。 Further, the shaft portion 43 is installed so as to be parallel to the shaft portion 33. Further, the first gears 41 and 42 are housed in the housing 2, respectively. The first gears 41 and 42 may be separated from each other.
　また、第２の歯車４２のピッチ円半径は、第１の歯車４１のピッチ円半径よりも小さい。この場合、第２の歯車４２のピッチ円半径は、第１の歯車４１のピッチ円半径の１／４～２／３であることが好ましく、１／３～１／２であることがより好ましい。ここで、第１の歯車４１が回動する際、減速回転軸が支点、第１の歯車４１が駆動歯車３２と噛合する位置が力点、第２の歯車４２がプランジャ５のラック５１３と噛合する位置が作用点となる。したがって、第２の歯車４２のピッチ円半径が第１の歯車４１のピッチ円半径よりも小さいことにより、第２の歯車の回転力が増幅されてラック５１３に伝達される。これにより、駆動歯車３２の回転速度が減速され、その駆動歯車３２の回転力がプランジャ５のラック５１３に伝達されるので、比較的小さい力で、操作部３１を回動操作して、プランジャ５を移動させることができる。 Further, the pitch circle radius of the second gear 42 is smaller than the pitch circle radius of the first gear 41. In this case, the pitch circle radius of the second gear 42 is preferably 1/4 to 2/3 of the pitch circle radius of the first gear 41, and more preferably 1/3 to 1/2. . Here, when the first gear 41 rotates, the reduction rotation shaft is a fulcrum, the position where the first gear 41 meshes with the drive gear 32 is the power point, and the second gear 42 meshes with the rack 513 of the plunger 5. The position is the point of action. Accordingly, when the pitch circle radius of the second gear 42 is smaller than the pitch circle radius of the first gear 41, the rotational force of the second gear is amplified and transmitted to the rack 513. As a result, the rotational speed of the drive gear 32 is reduced, and the rotational force of the drive gear 32 is transmitted to the rack 513 of the plunger 5. Can be moved.
　また、第１の歯車４１のピッチ円半径は、駆動歯車３２のピッチ円半径よりも大きい。この場合、第１の歯車４１のピッチ円半径は、駆動歯車３２のピッチ円半径の１．５～５倍であることが好ましく、２～３倍であることがより好ましい。これにより、駆動歯車３２の回転力が増幅されて第１の歯車４１に伝達されるため、より小さい力で、操作部３１を回動操作して、プランジャ５を移動させることができる。 Further, the pitch circle radius of the first gear 41 is larger than the pitch circle radius of the drive gear 32. In this case, the pitch circle radius of the first gear 41 is preferably 1.5 to 5 times, more preferably 2 to 3 times the pitch circle radius of the drive gear 32. Thereby, since the rotational force of the drive gear 32 is amplified and transmitted to the first gear 41, the operation unit 31 can be rotated with a smaller force to move the plunger 5.
　図２、図７および図９に示すように、プランジャ５は、シリンジ６の後述するガスケット８を先端方向、すなわち後述する外筒７内の基端位置から先端位置に向かって押圧する部材である。プランジャ５は、本体部５１と、本体部５１の先端部に設けられ、使用時にガスケット８に当接し、そのガスケット８を先端方向に押圧する押圧部５２とを有している。本体部５１は、先端側に設けられた主軸部５１１と、基端側に設けられ、歯車組立体４の第２の歯車４２に噛合するラック５１３と、主軸部５１１とラック５１３とを連結する連結部５１２とで構成されている。なお、主軸部５１１の軸方向とラック５１３の長手方向とは一致している。 As shown in FIGS. 2, 7 and 9, the plunger 5 is a member that presses a gasket 8, which will be described later, of the syringe 6 in the distal direction, that is, from a proximal end position in an outer cylinder 7 which will be described later toward the distal end position. . The plunger 5 includes a main body portion 51 and a pressing portion 52 that is provided at the distal end portion of the main body portion 51 and abuts against the gasket 8 during use and presses the gasket 8 in the distal end direction. The main body 51 is connected to the main shaft portion 511 provided on the distal end side, the rack 513 provided on the proximal end side and meshing with the second gear 42 of the gear assembly 4, and the main shaft portion 511 and the rack 513. The connection part 512 is comprised. Note that the axial direction of the main shaft portion 511 and the longitudinal direction of the rack 513 coincide.
　このプランジャ５は、ハウジング２内に、主軸部５１１の軸方向とハウジング２の長手方向とが一致し、かつ、主軸部５１１の軸方向に移動可能に設置されている。すなわち、まず、プランジャ５のラック５１３は、ハウジング２のレール２５に、その長手方向に移動可能に支持されている。そして、プランジャ５の主軸部５１１は、ハウジング２の支持部２３の孔２３１に挿入され、支持部２３の孔２３１に臨む縁部により移動方向が規制され、これにより、プランジャ５は、ハウジングの長手方向、すなわち主軸部５１１の軸方向のみに移動可能になっている。 The plunger 5 is installed in the housing 2 so that the axial direction of the main shaft portion 511 coincides with the longitudinal direction of the housing 2 and is movable in the axial direction of the main shaft portion 511. That is, first, the rack 513 of the plunger 5 is supported by the rail 25 of the housing 2 so as to be movable in the longitudinal direction. The main shaft portion 511 of the plunger 5 is inserted into the hole 231 of the support portion 23 of the housing 2, and the movement direction is restricted by the edge portion facing the hole 231 of the support portion 23. It can move only in the direction, that is, the axial direction of the main shaft portion 511.
　このプランジャ５は、ガスケット８に連結されていないので、ガスケット８を基端方向に移動させることはできない。これにより、使用後に、ガスケット８を基端方向移動させ、再度使用することが防止される。 Since this plunger 5 is not connected to the gasket 8, the gasket 8 cannot be moved in the proximal direction. This prevents the gasket 8 from being moved in the proximal direction after use and being used again.
　なお、本実施形態では、プランジャ５は、先端方向と基端方向とのそれぞれに移動可能になっているが、これに限らず、例えば、先端方向にのみ移動可能に設置されてもよい。 In the present embodiment, the plunger 5 is movable in the distal direction and the proximal direction. However, the plunger 5 is not limited thereto, and may be installed to be movable only in the distal direction, for example.
　また、プランジャ５の押圧部５２は、本実施形態では、板状をなし、その平面視での形状は、円形状をなしている。この押圧部５２は、主軸部５１１の先端に設けられている。 In addition, the pressing portion 52 of the plunger 5 has a plate shape in the present embodiment, and the shape in plan view is a circular shape. The pressing portion 52 is provided at the tip of the main shaft portion 511.
　初期状態、すなわち未使用状態では、押圧部５２は、シリンジ６の後述するガスケット８の芯部材８２から基端方向に所定距離離間した位置に位置している（図１、図１３、図１４参照）。これにより、液体投与具１を組み立てる際、プランジャ５とシリンジ６との干渉を防止することができ、容易かつ確実に、組み立てることができる。なお、以下では、未使用状態のときのプランジャ５の位置を「初期位置」と言う。 In the initial state, that is, in the unused state, the pressing portion 52 is located at a position spaced apart from the core member 82 of the gasket 8 (described later) of the syringe 6 by a predetermined distance in the proximal direction (see FIGS. 1, 13, and 14). ). Thereby, when assembling the liquid administration tool 1, interference with the plunger 5 and the syringe 6 can be prevented, and it can assemble easily and reliably. Hereinafter, the position of the plunger 5 when not in use is referred to as an “initial position”.
　また、未使用状態では、ラック５１３の基端部がハウジング２の基端壁に当接し、これにより、プランジャ５の基端方向への移動が阻止されている（図１４参照）。これにより、未使用状態では、操作部３１を、プランジャ５が基端方向へ移動する方向に回転させようとしても操作部３１は回転しない。 In the unused state, the base end portion of the rack 513 contacts the base end wall of the housing 2, thereby preventing the plunger 5 from moving in the base end direction (see FIG. 14). Thereby, in the unused state, even if it is going to rotate the operation part 31 in the direction where the plunger 5 moves to a base end direction, the operation part 31 does not rotate.
　なお、操作部３１と、ハウジング２とに、プランジャ５が初期位置に位置していることを示す図示しない指標や目印を設けてもよい。 In addition, you may provide the indicator and mark which are not shown in the operation part 31 and the housing 2 which show that the plunger 5 is located in the initial position.
　また、プランジャ５の連結部５１２は、本実施形態では、Ｌ字状をなしている。この連結部５１２を介在させることで、ラック５１３は、プランジャ５の軸、すなわち、主軸部５１１の軸からずれた位置に配置されている。これにより、ガスケット８の上方、すなわちガスケット８の基端側の空間に、回転体３や歯車組立体４を配置することができ、これによって、液体投与具１の小型化を図ることができる。 Further, the connecting portion 512 of the plunger 5 has an L shape in this embodiment. By interposing this connecting portion 512, the rack 513 is disposed at a position shifted from the axis of the plunger 5, that is, the axis of the main shaft portion 511. Thereby, the rotating body 3 and the gear assembly 4 can be disposed above the gasket 8, that is, in the space on the proximal end side of the gasket 8, whereby the liquid administration device 1 can be reduced in size.
　図１３に示すように、操作部３１を図１３中の時計回りに回転させると、操作部３１とともに駆動歯車３２が図１３中の時計回りに回転する、すなわち、回転体３が図１３中の時計回りに回転する。そして、駆動歯車３２に噛合する第１の歯車４１が図１３中の反時計回りに回転し、第１の歯車４１とともに第２の歯車４２が図１３中の反時計回りに回転する、すなわち、歯車組立体４が図１３中の反時計回りに回転する。 As shown in FIG. 13, when the operation unit 31 is rotated clockwise in FIG. 13, the drive gear 32 is rotated together with the operation unit 31 in the clockwise direction in FIG. 13, that is, the rotating body 3 is in FIG. 13. Rotate clockwise. Then, the first gear 41 meshing with the drive gear 32 rotates counterclockwise in FIG. 13, and the second gear 42 together with the first gear 41 rotates counterclockwise in FIG. The gear assembly 4 rotates counterclockwise in FIG.
　そして、第２の歯車４２の回転運動は、プランジャ５のラック５１３の直線運動に変換される。すなわち、第２の歯車４２の回転力がプランジャ５のラック５１３に伝達され、プランジャ５が先端方向に移動し、その押圧部５２がシリンジ６のガスケット８を先端方向に押圧する。これにより、ガスケット８は、外筒７内を先端方向に移動する。 Rotational motion of the second gear 42 is converted into linear motion of the rack 513 of the plunger 5. That is, the rotational force of the second gear 42 is transmitted to the rack 513 of the plunger 5, the plunger 5 moves in the distal direction, and the pressing portion 52 presses the gasket 8 of the syringe 6 in the distal direction. As a result, the gasket 8 moves in the distal direction in the outer cylinder 7.
　ここで、この液体投与具１では、操作部３１のうちのハウジング２の側部から外部に突出している部位を先端方向に移動させるようにして、回転体３、すなわち駆動歯車３２を回転させると、プランジャ５が先端方向に移動し、ガスケット８が先端方向にする。この場合は、操作部３１の操作の方向とプランジャ５の移動方向とが一致し、これにより、違和感なく、操作することができる。 Here, in the liquid administration device 1, when the rotating body 3, that is, the drive gear 32 is rotated such that a portion of the operation portion 31 that protrudes from the side portion of the housing 2 to the outside is moved in the distal direction. The plunger 5 moves in the distal direction, and the gasket 8 moves in the distal direction. In this case, the operation direction of the operation unit 31 and the movement direction of the plunger 5 coincide with each other, thereby enabling operation without a sense of incongruity.
　図２および図８に示すように、シリンジ６は、先端部に底部と基端部に開口部とが設けられ、内部に液体を充填可能な外筒７と、外筒７の底部に装着され、先端に鋭利な針先９１を有し、基端が外筒７と連通する針管９と、外筒７内で外筒７の軸方向に沿って後述する基端位置から先端位置まで移動し得るガスケット８とを備えている。 As shown in FIGS. 2 and 8, the syringe 6 is provided with a bottom portion at the distal end portion and an opening portion at the proximal end portion, and is mounted on the outer cylinder 7 that can be filled with liquid, and the bottom portion of the outer cylinder 7. A needle tube 9 having a sharp needle tip 91 at the distal end and a proximal end communicating with the outer cylinder 7, and moving from the proximal end position, which will be described later, to the distal end position along the axial direction of the outer cylinder 7 within the outer cylinder 7. And a gasket 8 to be obtained.
　外筒７は、先端部に底部と基端部に開口部とが設けられた有底筒状の部材で構成されている。外筒７の側壁は、本実施形態では、円筒状をなしている。また、外筒７の底部、すなわち先端部においては、その外径および内径が基端側から先端側に向って漸減している。そして、外筒７の先端部の中央部に、針管９が装着されている。なお、外筒７の先端部の頂部が、液体を排出する排出口を構成しており、その排出口を介して液体が投与される。また、外筒７の基端の外周には、板状のフランジ７１が一体的に形成されている。 The outer cylinder 7 is composed of a bottomed cylindrical member having a bottom portion at the tip and an opening at the base end. In the present embodiment, the side wall of the outer cylinder 7 has a cylindrical shape. Further, the outer diameter and the inner diameter of the bottom portion of the outer cylinder 7, that is, the distal end portion, gradually decrease from the proximal end side toward the distal end side. A needle tube 9 is attached to the central portion of the distal end portion of the outer cylinder 7. In addition, the top part of the front-end | tip part of the outer cylinder 7 comprises the discharge port which discharges | emits a liquid, and a liquid is administered through the discharge port. A plate-like flange 71 is integrally formed on the outer periphery of the base end of the outer cylinder 7.
　このような外筒７内には、ガスケット８が外筒７の軸方向に沿って摺動可能（移動可能）に収納されて（挿入されて）いる。ガスケット８は、弾性材料で構成されたガスケット本体８１と、ガスケット本体８１の基端側に設けられ、ガスケット本体８１を支持する芯部材８２とを有している。 In such an outer cylinder 7, a gasket 8 is accommodated (inserted) so as to be slidable (movable) along the axial direction of the outer cylinder 7. The gasket 8 includes a gasket main body 81 made of an elastic material, and a core member 82 that is provided on the proximal end side of the gasket main body 81 and supports the gasket main body 81.
　芯部材８２の基端は、ガスケット本体８１の基端よりも基端側に位置しており、使用時には、その芯部材８２の基端面に、プランジャ５の押圧部５２が当接するようになっている。 The base end of the core member 82 is located on the base end side with respect to the base end of the gasket body 81, and the pressing portion 52 of the plunger 5 comes into contact with the base end surface of the core member 82 in use. Yes.
　ガスケット本体８１の外周部には、複数（本実施形態では２つ）のリング状の突部８１１が全周にわたって形成されており、これらの突部８１１が外筒７の内周面に密着しつつ摺動することで、液密性をより確実に保持するとともに、摺動性の向上が図れる。 A plurality (two in this embodiment) of ring-shaped protrusions 811 are formed on the entire outer periphery of the gasket body 81, and these protrusions 811 are in close contact with the inner peripheral surface of the outer cylinder 7. By sliding while sliding, the liquid-tightness can be more reliably maintained and the slidability can be improved.
　また、ガスケット本体８１には、その基端面に開放する中空部が形成されており、その中空部には、芯部材８２の先端部が嵌入され、これにより芯部材８２がガスケット本体８１を支持する。 The gasket body 81 is formed with a hollow portion that opens to the base end surface thereof, and the distal end portion of the core member 82 is fitted into the hollow portion, whereby the core member 82 supports the gasket body 81. .
　なお、ガスケット本体８１と芯部材８２は、嵌合による連結に限らず、例えば、螺合等により連結された構成、接着、融着等により固着された構成、芯部材８２を省略した構成であってもよい。 The gasket body 81 and the core member 82 are not limited to the connection by fitting, for example, a structure connected by screwing or the like, a structure fixed by adhesion, fusion, or the like, or a structure in which the core member 82 is omitted. May be.
　このガスケット８と外筒７とで囲まれた空間には、予め液体が充填されている。そして、ガスケット８が先端方向に向かって、すなわち、外筒７内の基端位置から先端位置に移動することにより、外筒７内の液体を針管９から押し出すこと、すなわち、排出することができる。ここで、ガスケット８の基端位置とは、ガスケット８と外筒７とで囲まれた空間に液体が充填された状態での外筒７の軸方向におけるガスケット８の位置であり、ガスケット８の先端位置とは、前述の充填された液体がすべて排出された状態での外筒７の軸方向におけるガスケット８の位置である。 The space surrounded by the gasket 8 and the outer cylinder 7 is filled with a liquid in advance. Then, by moving the gasket 8 toward the distal end, that is, from the base end position in the outer cylinder 7 to the distal end position, the liquid in the outer cylinder 7 can be pushed out from the needle tube 9, that is, discharged. . Here, the base end position of the gasket 8 is the position of the gasket 8 in the axial direction of the outer cylinder 7 in a state where the space surrounded by the gasket 8 and the outer cylinder 7 is filled with the liquid. The tip position is the position of the gasket 8 in the axial direction of the outer cylinder 7 in a state where all of the filled liquid is discharged.
　なお、外筒７、芯部材８２、ハウジング２、回転体３、歯車組立体４、プランジャ５の構成材料としては、それぞれ、特に限定されず、例えば、ポリ塩化ビニル、ポリエチレン、ポリプロピレン、環状ポリオレフィン、ポリスチレン、ポリ－（４－メチルペンテン－１）、ポリカーボネート、アクリル樹脂、アクリルニトリル－ブタジエン－スチレン共重合体、ポリエチレンテレフタレート、ポリエチレンナフタレート等のポリエステル、ブタジエン－スチレン共重合体、ポリアミド（例えば、ナイロン６、ナイロン６・６、ナイロン６・１０、ナイロン１２）のような各種樹脂が挙げられるが、その中でも、成形が容易であるという点で、ポリプロピレン、環状ポリオレフィン、ポリエステル、ポリ－（４－メチルペンテン－１）のような樹脂が好ましい。 In addition, it does not specifically limit as a constituent material of the outer cylinder 7, the core member 82, the housing 2, the rotary body 3, the gear assembly 4, and the plunger 5, respectively, For example, polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, Polystyrene such as polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, nylon) 6, various types of resins such as nylon 6,6, nylon 6,10, nylon 12). Among them, polypropylene, cyclic polyolefin, polyester, poly- (4-methyl) are easy to mold. Like pentene-1) Resin.
　また、ガスケット本体８１の構成材料としては、特に限定されず、例えば、天然ゴム、ブチルゴム、イソプレンゴム、ブタジエンゴム、スチレン－ブタジエンゴム、シリコーンゴムのような各種ゴム材料や、ポリウレタン系、ポリエステル系、ポリアミド系、オレフィン系、スチレン系等の各種熱可塑性エラストマー、あるいはそれらの混合物等の弾性材料が挙げられる。 Further, the material constituting the gasket body 81 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, Examples thereof include various thermoplastic elastomers such as polyamide, olefin, and styrene, or elastic materials such as a mixture thereof.
　針管９は、外筒７の先端部の中央部に装着され、その先端に鋭利な針先９１を有している。そして、この針先９１で生体を穿刺することができる。また、針管９の内腔部（中空部）は、外筒７と連通しており、外筒７からの液体が通過する流路として機能する。そして、針先９１で生体を穿刺した状態で、その生体に流路を介して液体が注入される。 The needle tube 9 is attached to the center of the tip of the outer cylinder 7 and has a sharp needle tip 91 at the tip. A living body can be punctured with the needle tip 91. Further, the lumen (hollow part) of the needle tube 9 communicates with the outer cylinder 7 and functions as a flow path through which the liquid from the outer cylinder 7 passes. And in the state which punctured the biological body with the needle point 91, a liquid is inject | poured into the biological body through a flow path.
　針管９の構成材料としては、特に限定されず、例えば、ステンレス鋼、アルミニウムまたはアルミニウム合金、チタンまたはチタン合金のような金属材料で構成されている。 The constituent material of the needle tube 9 is not particularly limited. For example, the needle tube 9 is made of a metal material such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy.
　なお、針管９には、図示しないキャップが装着され、針管９は、そのキャップで覆われている。 Note that a cap (not shown) is attached to the needle tube 9, and the needle tube 9 is covered with the cap.
　このシリンジ６は、ハウジング２の装着部２４に装着されている。この場合、外筒７のフランジ７１が、装着部２４の係合部２４１、２４２に基端側から係合し、これにより、シリンジ６が装着部２４から離脱することが防止される。 The syringe 6 is mounted on the mounting portion 24 of the housing 2. In this case, the flange 71 of the outer cylinder 7 is engaged with the engaging portions 241 and 242 of the mounting portion 24 from the proximal end side, and thereby the syringe 6 is prevented from being detached from the mounting portion 24.
　次に、液体投与具１の組み立て手順についてその１例を説明する。 Next, an example of the procedure for assembling the liquid administration device 1 will be described.
　まず、図９に示すように、ハウジング２の第２のハウジング部材２ｂに、プランジャ５を設置する。この場合、プランジャ５のラック５１３をレール２５に設置し、主軸部５１１を、支持部２３の孔２３１の一部を形成する単位支持部２３ｂ内に挿入する。 First, as shown in FIG. 9, the plunger 5 is installed on the second housing member 2 b of the housing 2. In this case, the rack 513 of the plunger 5 is installed on the rail 25, and the main shaft portion 511 is inserted into the unit support portion 23 b that forms a part of the hole 231 of the support portion 23.
　次に、図１０に示すように、第２のハウジング部材２ｂに、歯車組立体４を設置する。この場合、歯車組立体４の軸部４３を、１対の軸受け２２の一部を構成する１対の単位支持部２２ｂに設置し、第２の歯車４２をラック５１３に噛合させる。 Next, as shown in FIG. 10, the gear assembly 4 is installed in the second housing member 2b. In this case, the shaft portion 43 of the gear assembly 4 is installed on a pair of unit support portions 22 b constituting a part of the pair of bearings 22, and the second gear 42 is engaged with the rack 513.
　次に、図１１に示すように、第２のハウジング部材２ｂに、回転体３を設置する。この場合、回転体３の軸部３３を、１対の軸受け２１の一部を構成する１対の単位支持部２１ｂに設置し、駆動歯車３２を第１の歯車４１に噛合させる。 Next, as shown in FIG. 11, the rotating body 3 is installed in the second housing member 2b. In this case, the shaft portion 33 of the rotating body 3 is installed on a pair of unit support portions 21 b constituting a part of the pair of bearings 21, and the drive gear 32 is engaged with the first gear 41.
　次に、図１２に示すように、第２のハウジング部材２ｂに、シリンジ６を装着する。この場合、外筒７のフランジ７１を、装着部２４の係合部２４２に基端側から係合させる。 Next, as shown in FIG. 12, the syringe 6 is attached to the second housing member 2b. In this case, the flange 71 of the outer cylinder 7 is engaged with the engaging portion 242 of the mounting portion 24 from the proximal end side.
　次に、第２のハウジング部材２ｂと第１のハウジング部材２ａとを接合する。この場合、第２のハウジング部材２ｂと第１のハウジング部材２ａとの位置合わせをしつつ、第２のハウジング部材２ｂの各突出部２７を第１のハウジング部材２ａの各孔２６に嵌入する。以上で、液体投与具１の組み立てが完了する。 Next, the second housing member 2b and the first housing member 2a are joined. In this case, the protrusions 27 of the second housing member 2b are fitted into the holes 26 of the first housing member 2a while aligning the second housing member 2b and the first housing member 2a. Thus, the assembly of the liquid administration device 1 is completed.
　次に、液体投与具１の使用の際の動作を説明する。 Next, the operation when using the liquid administration device 1 will be described.
　まず、図１３および図１４に示すように、未使用状態の液体投与具１を用意し、その液体投与具１の針管９を生体に穿刺する。 First, as shown in FIG. 13 and FIG. 14, an unused liquid administration device 1 is prepared, and a needle tube 9 of the liquid administration device 1 is punctured into a living body.
　次に、図１５～図１８に示すように、操作部３１を図１５中の時計回りに回転（回動）させ、外筒７内の液体を生体に投与する。操作部３１の操作は、例えば、手指や手の平等で行うことができる。 Next, as shown in FIGS. 15 to 18, the operation unit 31 is rotated (turned) clockwise in FIG. 15 to administer the liquid in the outer cylinder 7 to the living body. The operation of the operation unit 31 can be performed with a finger or a palm, for example.
　具体的には、操作部３１を操作して駆動歯車３２を回転させることにより、減速機構である歯車組立体４により、駆動歯車３２の回転が減速され、駆動歯車３２の回転力がプランジャ５のラック５１３に伝達され、プランジャ５が先端方向に移動し、プランジャ５の押圧部５２がガスケット８に当接する。 Specifically, by operating the operation unit 31 to rotate the drive gear 32, the rotation of the drive gear 32 is decelerated by the gear assembly 4, which is a reduction mechanism, and the rotational force of the drive gear 32 is applied to the plunger 5. Transmitted to the rack 513, the plunger 5 moves in the distal direction, and the pressing portion 52 of the plunger 5 comes into contact with the gasket 8.
　そして、操作部３１を操作して駆動歯車３２をさらに回転させると、プランジャ５がさらに先端方向に移動し、そのプランジャ５により、ガスケット８が先端方向に押圧されて先端方向に移動する。このようにして、ガスケット８が外筒７内の基端位置から先端位置に移動することにより、外筒７内の液体は、針管９から排出され、生体に投与される。 When the operation gear 31 is further operated to further rotate the drive gear 32, the plunger 5 further moves in the distal direction, and the plunger 8 is pressed in the distal direction by the plunger 5 and moved in the distal direction. Thus, the gasket 8 moves from the proximal end position in the outer cylinder 7 to the distal end position, whereby the liquid in the outer cylinder 7 is discharged from the needle tube 9 and administered to the living body.
　以上説明したように、この液体投与具１によれば、歯車組立体４により、駆動歯車３２の回転を減速し、その駆動歯車３２の回転力をラック５１３に伝達してプランジャ５を移動するので、液体の投与の際の操作部３１の操作に必要な力を小さくすることができ、これにより、比較的粘度の高い液体でも容易かつ確実にその液体を投与することができる。 As described above, according to the liquid administration device 1, the gear assembly 4 decelerates the rotation of the drive gear 32 and transmits the rotational force of the drive gear 32 to the rack 513 to move the plunger 5. The force required for the operation of the operation unit 31 during the administration of the liquid can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably administered.
　また、歯車組立体４により、駆動歯車３２の回転を減速し、その駆動歯車３２の回転力をラック５１３に伝達してプランジャ５を移動するので、容易に、液体の投与速度を遅くすることができる。これにより、投与速度を遅くする必要がある液体を容易かつ確実に投与することができ、また、液体の投与の際の痛みを低減することができ、また、液体の漏出等を防止することができる。 Further, since the gear assembly 4 decelerates the rotation of the drive gear 32 and transmits the rotational force of the drive gear 32 to the rack 513 to move the plunger 5, the liquid administration speed can be easily reduced. it can. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
　また、プランジャ５の移動は、操作部３１を回動操作することによりなされるので、例えば、手指が不自由で、プランジャ５を直接押圧操作することが困難な使用者でも、手の平等を使用して操作部３１を操作し、容易に液体を投与することができる。 Further, since the plunger 5 is moved by rotating the operation unit 31, for example, even a user who has difficulty with fingers and is difficult to press the plunger 5 directly uses the palm of his hand. By operating the operation unit 31, the liquid can be easily administered.
　なお、本実施形態では、操作部３１および駆動歯車３２が軸部３３に固定され、軸部３３がハウジング２に対して回動自在に設置されているが、これに限らず、例えば、軸部３３がハウジング２に固定され、操作部３１および駆動歯車３２が軸部３３に対して回動自在に設置されていてもよい。 In the present embodiment, the operation unit 31 and the drive gear 32 are fixed to the shaft portion 33, and the shaft portion 33 is rotatably installed with respect to the housing 2. However, the present invention is not limited to this. 33 may be fixed to the housing 2, and the operation unit 31 and the drive gear 32 may be rotatably installed with respect to the shaft unit 33.
　また、本実施形態では、第１の歯車４１および４２が軸部４３に固定され、軸部４３がハウジング２に対して回動自在に設置されているが、これに限らず、例えば、軸部４３がハウジング２に固定され、第１の歯車４１および４２が軸部４３に対して回動自在に設置されていてもよい。 In the present embodiment, the first gears 41 and 42 are fixed to the shaft portion 43, and the shaft portion 43 is rotatably installed with respect to the housing 2. However, the present invention is not limited to this. 43 may be fixed to the housing 2, and the first gears 41 and 42 may be rotatably installed with respect to the shaft portion 43.
　＜第２実施形態＞
　図１９は、本発明の液体投与具の第２実施形態を示す断面図である。なお、以下では、図１９中の上側を「基端（後端）」、下側を「先端」、上下方向を「軸方向」または「長手方向として説明を行う。また、図１９では、操作部３１およびラチェット１１については、側面図である。 Second Embodiment
FIG. 19 is a cross-sectional view showing a second embodiment of the liquid administration device of the present invention. In the following description, the upper side in Fig. 19 is referred to as "base end (rear end)", the lower side is referred to as "tip end", and the vertical direction is referred to as "axial direction" or "longitudinal direction." The part 31 and the ratchet 11 are side views.
　以下、第２実施形態について、前述した第１実施形態との相違点を中心に説明し、同様の事項については、その説明を省略する。 Hereinafter, the second embodiment will be described with a focus on differences from the first embodiment described above, and description of similar matters will be omitted.
　図１９に示すように、第２実施形態の液体投与具１は、回転体３の回転方向を規制する回転方向規制部として、歯車１１１と歯止め１１２とで構成されたラチェット１１を有している。 As shown in FIG. 19, the liquid administration device 1 according to the second embodiment includes a ratchet 11 including a gear 111 and a pawl 112 as a rotation direction restricting portion that restricts the rotation direction of the rotating body 3. .
　ラチェット１１の歯車１１１は、回転体３の軸部３３に固定されており、操作部３１および駆動歯車３２と同心的に配置されている。また、歯止め１１２は、ハウジング２に固定されている。 The gear 111 of the ratchet 11 is fixed to the shaft portion 33 of the rotating body 3 and is disposed concentrically with the operation portion 31 and the drive gear 32. Further, the pawl 112 is fixed to the housing 2.
　また、歯車１１１の歯は、図１９中の反時計回りに傾斜し、歯止め１１２は、歯車１１１の図１９中左側に配置されている。このラチェット１１により、回転体３の図１９中の反時計回りの回転が阻止され、回転体３は、図１９中の時計回りにのみ回転する。 Further, the teeth of the gear 111 are inclined counterclockwise in FIG. 19, and the pawl 112 is arranged on the left side of the gear 111 in FIG. The ratchet 11 prevents the rotating body 3 from rotating counterclockwise in FIG. 19, and the rotating body 3 rotates only clockwise in FIG.
　この液体投与具１によれば、前述した第１実施形態と同様の効果が得られる。 According to this liquid administration device 1, the same effect as in the first embodiment described above can be obtained.
　そして、この液体投与具１では、ラチェット１１により、操作部３１の図１９中の反時計回りの回転が阻止され、これにより、プランジャ５が基端方向に移動してしまうことを防止することができる。このため、例えば、プランジャ５とガスケット８とが連結されている場合でも、ガスケット８が基端方向に移動してしまうことを防止することができる。 In the liquid administration device 1, the ratchet 11 prevents the operation unit 31 from rotating counterclockwise in FIG. 19, thereby preventing the plunger 5 from moving in the proximal direction. it can. For this reason, for example, even when the plunger 5 and the gasket 8 are connected, it is possible to prevent the gasket 8 from moving in the proximal direction.
　以上、本発明の液体投与具を、図示の実施形態に基づいて説明したが、本発明はこれに限定されるものではなく、各部の構成は、同様の機能を有する任意の構成のものに置換することができる。また、本発明に、他の任意の構成物が付加されていてもよい。 The liquid administration device of the present invention has been described based on the illustrated embodiment, but the present invention is not limited to this, and the configuration of each part is replaced with an arbitrary configuration having the same function. can do. In addition, any other component may be added to the present invention.
　また、本発明は、前記各実施形態のうちの、任意の２以上の構成（特徴）を組み合わせたものであってもよい。 Further, the present invention may be a combination of any two or more configurations (features) of the above embodiments.
　また、前記実施形態の液体投与具は、シリンジが予めハウジングの装着部に装着されている使い捨てタイプであるが、本発明では、これに限らず、例えば、シリンジがハウジングの装着部に着脱自在に装着されるように構成されていてもよい。すなわち、シリンジがカートリッジになっており、液体投与具は、繰り返して使用できるようになっていてもよい。なお、この場合、シリンジは、フランジがなく、先端部の排出口がゴム栓によって封止された外筒と、この外筒を支持し、先端部に外筒のゴム栓を刺通可能な両頭針を装着可能であり、基端部に螺合部を有するホルダーとを備え、ホルダーの螺合部により、シリンジがハウジングの装着部に着脱自在に装着されるように構成されてもよい。 In addition, the liquid administration device of the above embodiment is a disposable type in which a syringe is previously mounted on the mounting portion of the housing. However, the present invention is not limited thereto, and for example, the syringe is detachable from the mounting portion of the housing. You may be comprised so that it may mount | wear. That is, the syringe may be a cartridge, and the liquid administration device may be used repeatedly. In this case, the syringe has no flange, the outer cylinder in which the discharge port at the tip is sealed with a rubber stopper, and both heads that support the outer cylinder and can be pierced with the rubber stopper of the outer cylinder at the tip. A needle can be attached, and a holder having a threaded portion at the proximal end portion is provided, and the syringe can be detachably mounted on the housing mounted portion by the threaded portion of the holder.
　また、前記実施形態では、予めシリンジに液体が充填されているが、本発明では、これに限らず、後からシリンジに液体を充填するよう構成されていてもよい。 In the above embodiment, the syringe is preliminarily filled with the liquid. However, the present invention is not limited to this, and the syringe may be filled with the liquid later.
　また、前記実施形態では、液体投与具の構成物にシリンジが含まれているが、本発明では、これに限らず、液体投与具の構成物にシリンジが含まれていなくてもよい。 In the above embodiment, the syringe is included in the component of the liquid administration device. However, the present invention is not limited to this, and the syringe may not be included in the component of the liquid administration device.
　また、前記実施形態では、操作部は、円盤状をなしているが、本発明では、操作部は、回転体の一部を構成していれば、いかなる形状をなしていてもよい。操作部の他の形状としては、例えば、駆動回転軸から駆動歯車の径方向に延びた棒状等が挙げられる。 In the embodiment, the operation unit has a disk shape. However, in the present invention, the operation unit may have any shape as long as it forms a part of the rotating body. Examples of other shapes of the operation unit include a rod shape extending in the radial direction of the drive gear from the drive rotation shaft.
　また、円盤状の操作部の外周部に、その周方向に沿って、径方向に突出する複数の突起が形成されていてもよい。この場合、各突起は、等角度間隔で配置されていることが好ましい。なお、前記突起の数は、１つでもよい。 Further, a plurality of protrusions protruding in the radial direction along the circumferential direction may be formed on the outer peripheral part of the disk-shaped operation part. In this case, it is preferable that the protrusions are arranged at equiangular intervals. The number of the protrusions may be one.
　また、円盤状の操作部の一部に、切り欠きが形成されていてもよい。この場合、ガスケットが基端位置から先端位置まで移動する間、その切り欠きがハウジング内に位置するように構成することが好ましい。 Further, a notch may be formed in a part of the disk-shaped operation unit. In this case, it is preferable that the notch is located in the housing while the gasket moves from the proximal end position to the distal end position.
　また、操作部が駆動歯車の外周部から構成され、その外周部を操作することによって駆動歯車を回動するようにしてもよい。この場合、駆動歯車は、少なくともその一部がハウジングから外部に突出するようになっている。 Further, the operation unit may be constituted by the outer peripheral part of the drive gear, and the drive gear may be rotated by operating the outer peripheral part. In this case, at least a part of the drive gear protrudes from the housing to the outside.
　また、前記実施形態では、減速機構は、第１の歯車４１と第２の歯車４２とを有する歯車組立体４で構成されているが、本発明では、これに限らず、例えば、駆動歯車と第１の歯車との間に他の１つまたは複数の歯車が介在していてもよく、また、第２の歯車とラックとの間に他の１つまたは複数の歯車が介在していてもよい。ただし、他の歯車が介在すると、駆動歯車からプランジャのラックに伝達される回転力が低下するため、前記実施形態のように、駆動歯車と第１の歯車とが噛合し、第２の歯車とラックとが噛合することが好ましい。 In the above-described embodiment, the speed reduction mechanism is configured by the gear assembly 4 having the first gear 41 and the second gear 42. However, the present invention is not limited to this. One or more other gears may be interposed between the first gear and one or more other gears may be interposed between the second gear and the rack. Good. However, when another gear is interposed, the rotational force transmitted from the drive gear to the rack of the plunger is reduced, so that the drive gear and the first gear mesh with each other as in the above embodiment, and the second gear and It is preferable that the rack meshes.
　また、駆動歯車と減速機構とは、ウォームギアから構成されていてもよい。この場合、駆動歯車は、円柱に螺旋状に連続的に歯を切ったウォームであり、減速機構は、このウォームに併せて円盤の側面に歯を切ったウォームホイールである。 Further, the drive gear and the speed reduction mechanism may be composed of a worm gear. In this case, the drive gear is a worm whose teeth are continuously cut in a spiral shape on a cylinder, and the speed reduction mechanism is a worm wheel whose teeth are cut on the side surface of the disk in accordance with the worm.
　本発明の液体投与具は、先端部に排出口が設けられ、液体が充填され、筒状をなす外筒と、前記外筒内を摺動可能に設置されたガスケットとを有するシリンジを装着し、前記排出口を介して前記液体を投与する液体投与具であって、
　先端部に前記シリンジが装着される装着部を有するハウジングと、
　駆動回転軸を具備し、前記ハウジング内に前記駆動回転軸を中心に回動可能に設置された駆動歯車と、少なくとも一部が前記ハウジングから外部に突出し、操作して前記駆動歯車を回動させる操作部とを有する回転体と、
　ラックを有し、前記ハウジング内に先端方向に移動可能に設置され、前記ガスケットを先端方向に押圧するプランジャと、
　前記駆動歯車の回転速度を減速し、該駆動歯車の回転力を前記ラックに伝達する減速機構とを備え、
　前記装着部に前記シリンジが装着された装着状態で、前記操作部を操作して前記駆動歯車を回動させることにより、前記減速機構により、前記駆動歯車の回転速度が減速され、該駆動歯車の回転力が前記ラックに伝達され、前記プランジャが先端方向に移動し、該プランジャにより、前記ガスケットが先端方向に押圧されて先端方向に移動するよう構成されていることを特徴とする。 The liquid administration device of the present invention is provided with a syringe having a discharge port provided at the tip, filled with a liquid, and having a cylindrical outer cylinder and a gasket slidably installed in the outer cylinder. A liquid administration device for administering the liquid through the outlet,
A housing having a mounting portion to which the syringe is mounted at a tip portion;
A drive gear provided with a drive rotary shaft and installed in the housing so as to be rotatable around the drive rotary shaft, and at least a part of the drive gear protrudes from the housing and is operated to rotate the drive gear. A rotating body having an operation unit;
A plunger having a rack, installed in the housing so as to be movable in a distal direction, and pressing the gasket in the distal direction;
A reduction mechanism that reduces the rotational speed of the drive gear and transmits the rotational force of the drive gear to the rack;
By rotating the drive gear by operating the operation unit in a mounted state in which the syringe is mounted on the mounting unit, the rotational speed of the drive gear is reduced by the reduction mechanism, and the drive gear Rotational force is transmitted to the rack, the plunger moves in the distal direction, and the plunger is pressed in the distal direction by the plunger to move in the distal direction.
　本発明によれば、減速機構により減速してプランジャを移動するので、液体の投与の操作に必要な力を小さくすることができ、これにより、比較的粘度の高い液体でも容易かつ確実にその液体を投与することができる。 According to the present invention, since the plunger is moved while being decelerated by the deceleration mechanism, the force required for the liquid administration operation can be reduced, so that even a liquid having a relatively high viscosity can be easily and reliably obtained. Can be administered.
　また、容易に、液体の投与速度を遅くすることができる。これにより、投与速度を遅くする必要がある液体を容易かつ確実に投与することができ、また、液体の投与の際の痛みを低減することができ、また、液体の漏出等を防止することができる。 Also, the liquid administration rate can be easily reduced. As a result, it is possible to easily and reliably administer a liquid that needs to be administered at a low rate, reduce pain during the administration of the liquid, and prevent leakage of the liquid. it can.
　また、プランジャの移動は、操作部により回転体を回動操作することによりなされるので、例えば、手指が不自由で、プランジャを直接押圧操作することが困難な使用者でも、手の平等を使用して操作部を操作し、容易に液体を投与することができる。 In addition, since the plunger is moved by rotating the rotating body with the operation unit, for example, even a user who has difficulty with fingers and cannot easily press the plunger directly uses the palm of his hand. By operating the operation unit, the liquid can be easily administered.
　したがって産業上の利用可能性を有する。 Therefore, it has industrial applicability.
　１　　　　　　　液体投与具
　２　　　　　　　ハウジング
　２ａ　　　　　　第１のハウジング部材
　２ｂ　　　　　　第２のハウジング部材
　２１、２２　　　軸受け
　２１ａ、２１ｂ、２２ａ、２２ｂ　単位支持部
　２３　　　　　　支持部
　２３ａ、２３ｂ　単位支持部
　２３１　　　　　孔
　２４　　　　　　装着部
　２４１、２４２　係合部
　２５　　　　　　レール
　２６　　　　　　孔
　２７　　　　　　突出部
　２８　　　　　　開口
　３　　　　　　　回転体
　３１　　　　　　操作部
　３２　　　　　　駆動歯車
　３３　　　　　　軸部
　４　　　　　　　歯車組立体
　４１　　　　　　第１の歯車
　４２　　　　　　第２の歯車
　４３　　　　　　軸部
　５　　　　　　　プランジャ
　５１　　　　　　本体部
　５１１　　　　　主軸部
　５１２　　　　　連結部
　５１３　　　　　ラック
　５２　　　　　　押圧部
　６　　　　　　　シリンジ
　７　　　　　　　外筒
　７１　　　　　　フランジ
　８　　　　　　　ガスケット
　８１　　　　　　ガスケット本体
　８１１　　　　　突部
　８２　　　　　　芯部材
　９　　　　　　　針管
　９１　　　　　　針先
　１１　　　　　　ラチェット
　１１１　　　　　歯車
　１１２　　　　　歯止め DESCRIPTION OF SYMBOLS 1 Liquid administration tool 2 Housing 2a 1st housing member 2b 2nd housing member 21 and 22 Bearing 21a, 21b, 22a, 22b Unit support part 23 Support part 23a, 23b Unit support part 231 Hole 24 Mounting part 241,242 Engagement Joint portion 25 Rail 26 Hole 27 Projection portion 28 Opening 3 Rotating body 31 Operation portion 32 Drive gear 33 Shaft portion 4 Gear assembly 41 First gear 42 Second gear 43 Shaft portion 5 Plunger 51 Main body portion 511 Main shaft portion 512 Connection 513 Rack 52 Pressing part 6 Syringe 7 Outer cylinder 71 Flange 8 Gasket 81 Gasket body 811 Protruding part 82 Core member 9 Needle tube 91 Needle tip 11 Ratchet 111 gear 112 pawl

Claims (9)

  1. 　先端部に排出口が設けられ、液体が充填され、筒状をなす外筒と、前記外筒内を摺動可能に設置されたガスケットとを有するシリンジを装着し、前記排出口を介して前記液体を投与する液体投与具であって、
    　先端部に前記シリンジが装着される装着部を有するハウジングと、
    　駆動回転軸を具備し、前記ハウジング内に前記駆動回転軸を中心に回動可能に設置された駆動歯車と、少なくとも一部が前記ハウジングから外部に突出し、操作して前記駆動歯車を回動させる操作部とを有する回転体と、
    　ラックを有し、前記ハウジング内に先端方向に移動可能に設置され、前記ガスケットを先端方向に押圧するプランジャと、
    　前記駆動歯車の回転速度を減速し、該駆動歯車の回転力を前記ラックに伝達する減速機構とを備え、
    　前記装着部に前記シリンジが装着された装着状態で、前記操作部を操作して前記駆動歯車を回動させることにより、前記減速機構により、前記駆動歯車の回転速度が減速され、該駆動歯車の回転力が前記ラックに伝達され、前記プランジャが先端方向に移動し、該プランジャにより、前記ガスケットが先端方向に押圧されて先端方向に移動するよう構成されていることを特徴とする液体投与具。     A discharge port is provided at the distal end, and a syringe having a cylindrical outer cylinder filled with a liquid and a gasket slidably installed in the outer cylinder is mounted, and the A liquid administration device for administering a liquid,
    A housing having a mounting portion to which the syringe is mounted at a tip portion;
    A drive gear provided with a drive rotary shaft and installed in the housing so as to be rotatable around the drive rotary shaft, and at least a part of the drive gear protrudes from the housing and is operated to rotate the drive gear. A rotating body having an operation unit;
    A plunger having a rack, installed in the housing so as to be movable in a distal direction, and pressing the gasket in the distal direction;
    A reduction mechanism that reduces the rotational speed of the drive gear and transmits the rotational force of the drive gear to the rack;
    By rotating the drive gear by operating the operation unit in a mounted state in which the syringe is mounted on the mounting unit, the rotational speed of the drive gear is reduced by the reduction mechanism, and the drive gear Rotating force is transmitted to the rack, the plunger moves in the distal direction, and the plunger is pressed in the distal direction by the plunger to move in the distal direction.
  2. 　前記減速機構は、前記ハウジング内に回動可能に設置され、減速回転軸を具備し、前記駆動歯車の回動によって前記減速回転軸を中心に回動する第１の歯車と、前記第１の歯車よりもピッチ円半径が小さく、前記減速回転軸を中心に前記第１の歯車と一体的に回動し、その回動に伴う回転力が前記ラックに伝達される第２の歯車とを有する歯車組立体を備える請求項１に記載の液体投与具。 The speed reduction mechanism is rotatably installed in the housing, includes a speed reduction rotation shaft, and rotates around the speed reduction rotation shaft by rotation of the drive gear; and the first gear A pitch circle radius smaller than that of the gear, and a second gear that rotates integrally with the first gear about the reduction rotation shaft and that transmits a rotational force associated with the rotation to the rack. The liquid administration device according to claim 1, comprising a gear assembly.
  3. 　前記第１の歯車のピッチ円半径は、前記駆動歯車のピッチ円半径よりも大きい請求項２に記載の液体投与具。 The liquid administration device according to claim 2, wherein a pitch circle radius of the first gear is larger than a pitch circle radius of the drive gear.
  4. 　前記ハウジングの前記ラックに対して、前記減速回転軸を挟んだ反対側の側部から、前記操作部の一部が外部に突出している請求項２に記載の液体投与具。 The liquid administration device according to claim 2, wherein a part of the operation portion protrudes to the outside from a side portion on the opposite side of the rack with respect to the rack of the housing.
  5. 　前記操作部の前記ハウジングの前記側部から外部に突出している部位を先端方向に移動させるようにして前記駆動歯車を回転させると、前記プランジャが先端方向に移動するよう構成されている請求項４に記載の液体投与具。 5. The plunger is configured to move in the distal direction when the drive gear is rotated so that a portion of the operating portion that protrudes to the outside from the side portion of the housing is moved in the distal direction. A liquid administration device according to 1.
  6. 　前記操作部は、前記ハウジングの基端部に配置されており、前記操作部の一部が前記ハウジングの基端部から外部に突出している請求項４に記載の液体投与具。 The liquid administration device according to claim 4, wherein the operation portion is disposed at a proximal end portion of the housing, and a part of the operation portion projects outward from the proximal end portion of the housing.
  7. 　前記駆動回転軸から、前記操作部を操作する際の該操作部における力点までの距離が、前記駆動歯車のピッチ円半径よりも長い請求項１に記載の液体投与具。 The liquid administration device according to claim 1, wherein a distance from the drive rotation shaft to a power point in the operation unit when the operation unit is operated is longer than a pitch circle radius of the drive gear.
  8. 　前記操作部は、円盤状をなしている請求項１に記載の液体投与具。 The liquid administration device according to claim 1, wherein the operation unit has a disk shape.
  9. 　前記装着部に装着され、予め前記液体が充填された前記シリンジを有する請求項１に記載の液体投与具。 The liquid administration device according to claim 1, comprising the syringe that is attached to the attachment portion and is filled with the liquid in advance.
PCT/JP2012/074772 2012-09-26 2012-09-26 Liquid administration device WO2014049745A1 (en)

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US11406565B2 (en) 2015-03-10 2022-08-09 Regeneran Pharmaceuticals, Inc. Aseptic piercing system and method
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector

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US11406565B2 (en) 2015-03-10 2022-08-09 Regeneran Pharmaceuticals, Inc. Aseptic piercing system and method
WO2018204779A1 (en) * 2017-05-05 2018-11-08 Regeneron Pharmaceuticals, Inc. Auto-injector
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US11547801B2 (en) 2017-05-05 2023-01-10 Regeneron Pharmaceuticals, Inc. Auto-injector
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector

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