JP2017105819A5 - - Google Patents
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- Publication number
- JP2017105819A5 JP2017105819A5 JP2017022249A JP2017022249A JP2017105819A5 JP 2017105819 A5 JP2017105819 A5 JP 2017105819A5 JP 2017022249 A JP2017022249 A JP 2017022249A JP 2017022249 A JP2017022249 A JP 2017022249A JP 2017105819 A5 JP2017105819 A5 JP 2017105819A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- lys
- gly
- glu
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175094.5 | 2013-07-04 | ||
| EP13175094 | 2013-07-04 | ||
| US201361845646P | 2013-07-12 | 2013-07-12 | |
| US61/845,646 | 2013-07-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Division JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017105819A JP2017105819A (ja) | 2017-06-15 |
| JP2017105819A5 true JP2017105819A5 (cg-RX-API-DMAC7.html) | 2017-08-24 |
| JP6687557B2 JP6687557B2 (ja) | 2020-04-22 |
Family
ID=48703344
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Active JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
| JP2017022249A Active JP6687557B2 (ja) | 2013-07-04 | 2017-02-09 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Active JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9498534B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3016975B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6139712B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160029079A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105377884B (cg-RX-API-DMAC7.html) |
| AR (1) | AR096789A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014286234A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015032875A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2916311A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2015016875A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015000942A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2646538T3 (es) | 2013-06-20 | 2017-12-14 | Novo Nordisk A/S | Derivados de GLP-1 y sus usos |
| MX2015016875A (es) * | 2013-07-04 | 2016-04-07 | Novo Nordisk As | Derivados de peptidos similares a peptido similar a glucagon 1 (glp-1) y sus usos. |
| ES2739289T3 (es) | 2014-11-27 | 2020-01-30 | Novo Nordisk As | Derivados de GLP-1 y sus usos |
| CN107108714B (zh) | 2014-12-17 | 2022-02-08 | 诺和诺德股份有限公司 | Glp-1衍生物及其用途 |
| EP3302465A1 (en) | 2015-06-05 | 2018-04-11 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of demyelinating diseases |
| EA201891469A1 (ru) | 2015-12-23 | 2018-12-28 | Дзе Джонс Хопкинс Юниверсити | Агонист длительного действия glp-1r как терапия для лечения неврологических и нейродегенеративных патологических состояний |
| JP7053480B2 (ja) | 2016-03-03 | 2022-04-12 | ノヴォ ノルディスク アー／エス | Ｇｌｐ－１誘導体及びその使用 |
| JP7076442B2 (ja) | 2016-11-07 | 2022-05-27 | ノヴォ ノルディスク アー／エス | Ｐｅｇ化合物のｄｃｈｂｓ活性エステル及びその使用 |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| CN108976147B (zh) * | 2017-05-31 | 2021-02-12 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
| CN109248323B (zh) * | 2017-07-14 | 2023-09-08 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| US11130794B2 (en) | 2017-07-19 | 2021-09-28 | Novo Nordisk A/S | Bifunctional compounds |
| EP4360651A3 (en) | 2017-08-24 | 2024-07-17 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| EP3716965A1 (en) * | 2017-11-30 | 2020-10-07 | Société des Produits Nestlé S.A. | Polyketide compound and derivatives thereof for use in the prevention and treatment of a neurological disorder |
| MY202560A (en) | 2018-04-05 | 2024-05-08 | Sun Pharmaceutical Ind Ltd | Novel glp-1 analogues |
| CN113214381B (zh) * | 2018-04-19 | 2024-01-19 | 杭州先为达生物科技股份有限公司 | 酰化的glp-1衍生物 |
| WO2019200594A1 (zh) | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| CN110386974B (zh) * | 2018-04-19 | 2022-12-09 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| CN112385033A (zh) * | 2018-07-12 | 2021-02-19 | 三菱电机株式会社 | 半导体装置 |
| EP4085077A4 (en) | 2019-12-31 | 2024-01-17 | Beijing QL Biopharmaceutical Co., Ltd. | Fusion proteins of glp-1 and gdf15 and conjugates thereof |
| WO2021139744A1 (en) | 2020-01-11 | 2021-07-15 | Beijing Ql Biopharmaceutical Co., Ltd. | Conjugates of fusion proteins of glp-1 and fgf21 |
| KR20220143036A (ko) * | 2020-02-18 | 2022-10-24 | 노보 노르디스크 에이/에스 | 약학적 제형 |
| CN115925994B (zh) | 2020-09-30 | 2023-09-22 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| CN114685644A (zh) * | 2020-12-29 | 2022-07-01 | 苏州康宁杰瑞生物科技有限公司 | 一种人glp-1多肽变体及其应用 |
| CN117586423A (zh) | 2021-07-14 | 2024-02-23 | 北京质肽生物医药科技有限公司 | 用于代谢病症的融合多肽 |
| CA3252113A1 (en) | 2022-03-30 | 2023-10-05 | Beijing Ql Biopharmaceutical Co., Ltd. | Liquid pharmaceutical compositions of polypeptide conjugates and their methods of use |
| EP4642440A1 (en) | 2022-12-30 | 2025-11-05 | Algipharma As | Compositions and methods to increase the systemic bioavailability of a polypeptide therapeutic agent undergoing oral administration |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458924B2 (en) * | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| DE69942306D1 (de) * | 1998-02-27 | 2010-06-10 | Novo Nordisk As | Abkömmlinge von glp-1 analogen |
| HUP0200297A3 (en) | 1999-03-17 | 2002-09-30 | Novo Nordisk As | Method for acylating peptides and the glutaminic acid derivatives as acylating agents |
| EP1076066A1 (en) * | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| JP2003516322A (ja) | 1999-11-12 | 2003-05-13 | ノボ ノルディスク アクティーゼルスカブ | ベータ細胞変性抑制のためのｇｌｐ−１アゴニストの使用 |
| GB0020551D0 (en) | 2000-08-22 | 2000-10-11 | Birkett David | Sprinkler system |
| JP2006520818A (ja) | 2003-03-19 | 2006-09-14 | イーライ リリー アンド カンパニー | ポリエチレングリコール結合ｇｌｐ−１化合物 |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| ATE482724T1 (de) | 2005-05-13 | 2010-10-15 | Lilly Co Eli | Pegylierte glp-1-verbindungen |
| EP2514406A1 (en) | 2007-06-01 | 2012-10-24 | Novo Nordisk A/S | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier |
| WO2009030771A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| WO2009030738A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| CN102333788A (zh) | 2009-02-19 | 2012-01-25 | 诺沃—诺迪斯克有限公司 | 因子viii的修饰 |
| CN102686607B (zh) * | 2009-12-16 | 2014-10-29 | 诺沃—诺迪斯克有限公司 | 双酰化glp-1衍生物 |
| US9006178B2 (en) | 2010-11-09 | 2015-04-14 | Novo Nordisk A/S | Double-acylated GLP-1 derivatives with a linker |
| EP3225631B1 (en) | 2011-04-12 | 2019-01-09 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
| MX2015016875A (es) * | 2013-07-04 | 2016-04-07 | Novo Nordisk As | Derivados de peptidos similares a peptido similar a glucagon 1 (glp-1) y sus usos. |
-
2014
- 2014-07-02 MX MX2015016875A patent/MX2015016875A/es unknown
- 2014-07-02 EP EP14734816.3A patent/EP3016975B1/en active Active
- 2014-07-02 CN CN201480038380.6A patent/CN105377884B/zh active Active
- 2014-07-02 AU AU2014286234A patent/AU2014286234A1/en not_active Abandoned
- 2014-07-02 JP JP2015563070A patent/JP6139712B2/ja active Active
- 2014-07-02 KR KR1020167002151A patent/KR20160029079A/ko not_active Withdrawn
- 2014-07-02 BR BR112015032875A patent/BR112015032875A2/pt not_active Application Discontinuation
- 2014-07-02 WO PCT/EP2014/064033 patent/WO2015000942A1/en not_active Ceased
- 2014-07-02 US US14/322,077 patent/US9498534B2/en active Active
- 2014-07-02 CA CA2916311A patent/CA2916311A1/en not_active Withdrawn
- 2014-07-02 AR ARP140102467A patent/AR096789A1/es unknown
-
2016
- 2016-09-28 US US15/278,501 patent/US10010614B2/en active Active
-
2017
- 2017-02-09 JP JP2017022249A patent/JP6687557B2/ja active Active