JP2017096760A - Automatic analyzer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analyzer that can prevent deterioration of analysis data due to an influence of a sample in advance.SOLUTION: An automatic analyzer comprises: an analysis unit 10 that dispenses each sample and reagent of each examination item set to the sample in a reaction container, mesures a mixed liquid of the sample and reagent in the reaction container, and includes a cleaning nozzle conducting cleaning of the reaction container whenever a measurement of the mixed liquid is ended; a data processing unit 60 that generates analysis data by a measurement of the analysis unit 10; and an analysis control unit 41 that causes various units of the analysis unit 10 to be operated. The analysis control unit 41 is configured to suspend dispersion of the reagent of the examination item with respect to the reaction container where the dispersion of the sample having the examination item of which the analysis data becomes a value equal to or greater than a preset threshold set was conducted, of the reaction containers subjected to the cleaning by the cleaning nozzle.SELECTED DRAWING: Figure 1

Description

  Embodiments described herein relate generally to an automatic analyzer that dispenses a sample collected from a subject into a reaction vessel and analyzes components contained in the sample.

  Tests using automatic analyzers target biochemical test items, immunological test items, etc., and optically detect changes in color and turbidity caused by the reaction of the mixture of the sample collected from the specimen and the reagent used to analyze each test item. Measure automatically. By this measurement, analytical data represented by the concentrations of various test item components in the sample, enzyme activities, and the like are generated.

  In the automatic analyzer, an inspection item set in accordance with the inspection is analyzed from a plurality of inspection items for each sample. And a sample and the reagent of each test | inspection item are dispensed to reaction container, and the liquid mixture of the sample and reagent in reaction container is measured. After the measurement is completed, the reaction container is washed and then used for dispensing and measuring the next sample and reagent.

Japanese Unexamined Patent Publication No. 2014-20885

  However, some inspection items require analysis of trace components, and if these inspection items are set, a small sample that adheres to the reaction vessel despite being washed after the measurement is completed. There is a problem that the analysis data of the inspection item deteriorates due to the influence of contamination.

  The embodiment has been made to solve the above problems, and an object thereof is to provide an automatic analyzer that can prevent deterioration of analysis data due to the influence of a sample.

  In order to achieve the above object, the automatic analyzer of the embodiment dispenses each sample and a reagent for each inspection item set in the sample into a reaction container, and a mixture of the sample and the reagent in the reaction container. In the automatic analyzer that generates analysis data by measurement of the above, the analysis data is included in the cleaning nozzle that cleans the reaction container every time the measurement of the mixed solution is completed, and the reaction container that is cleaned by the cleaning nozzle. And an analysis control unit for stopping dispensing of the reagent of the test item to the reaction container in which the sample having the test item set to a value equal to or greater than a preset threshold value has been dispensed.

The block diagram which shows the structure of the automatic analyzer which concerns on embodiment. The perspective view which shows the structure of the analysis part which concerns on embodiment. The figure which shows each stop position of each reaction container which concerns on embodiment. The figure which shows an example of the avoidance parameter setting screen displayed on the display part which concerns on embodiment. The flowchart which shows an example of the procedure which determines whether use of each reaction container which concerns on embodiment is possible.

  Hereinafter, embodiments will be described with reference to the drawings.

  FIG. 1 is a block diagram illustrating a configuration of an automatic analyzer according to the embodiment. This automatic analyzer 100 dispenses a sample such as a standard sample or a test sample and a reagent for each inspection item, measures a mixed solution of the sample and the reagent, and generates standard data and test data. 10 is provided. Further, a drive unit 40 that drives various units of the analysis unit 10 and an analysis control unit 41 that controls the drive unit 40 are provided. In addition, a data processing unit 60 that generates calibration data and analysis data from the standard data and test data generated by the analysis unit 10 is provided.

  The automatic analyzer 100 further includes an output unit 70 that outputs calibration data and analysis data generated by the data processing unit 60. Further, an input for setting analysis parameters such as sample and reagent dispensing amounts for each inspection item, an input for setting inspection parameters for avoiding the influence of contamination of the sample and a threshold, and an analysis unit 10 And an operation unit 80 for performing input for setting dispensing information including information on a sample to be dispensed and information on a reagent. In addition, a system control unit 90 that controls the analysis control unit 41, the data processing unit 60, and the output unit 70 is provided.

  FIG. 2 is a perspective view showing the configuration of the analysis unit 10. The analysis unit 10 includes a sample container 11 for storing a sample such as a standard sample or a test sample, and a sample table 12 for holding the sample container 11 so as to be movable. In addition, a reagent container 13 is provided that accommodates each liquid of the 1-reagent system and 2-reagent system first reagent of each inspection item, the second reagent that forms a pair with the 2-reagent system first reagent, and the cleaning liquid. In addition, two reagent racks 14 that hold the reagent containers 13 in a movable manner are provided.

  In addition, a reagent storage 15 that cools the first reagent and the cleaning liquid in the reagent container 13 held in the reagent rack 14 and a reagent storage 16 that cools the second reagent in the reagent container 13 held in the reagent rack 14 are provided. I have. Further, for example, 165 reaction vessels 17 arranged in a line at equal intervals on the circumference, and a reaction table 18 that holds the reaction vessels 17 so as to be rotatable are provided.

  In addition, a sample dispensing probe 19 that performs dispensing to suck the sample in the sample container 11 held on the sample table 12 and discharge the sample into the reaction container 17, and a sample that holds the sample dispensing probe 19 movably. A dispensing arm 20 is provided. In addition, the first reagent dispensing probe 21 for dispensing the first reagent and the cleaning liquid in the reagent container 13 held in the reagent rack 14 and sucking them into the reaction container 17, and the first reagent dispensing. And a first reagent dispensing arm 22 that holds the probe 21 in a movable manner.

  Moreover, the 1st stirring element 23 which stirs the liquid mixture of the sample and the 1st reagent dispensed to the reaction container 17, and the 1st stirring arm 24 which hold | maintains the 1st stirring element 23 so that a movement is possible are provided. A second reagent dispensing probe 25 for aspirating the second reagent in the reagent container 13 held in the reagent rack 14 and dispensing it into the reaction container 17 into which the first reagent has been dispensed; A second reagent dispensing arm 26 that holds the second reagent dispensing probe 25 in a movable manner is provided.

  In addition, a second stirrer 27 that stirs the sample dispensed in the reaction vessel 17, a mixed solution of the first reagent and the second reagent, and a second stirrer arm 28 that holds the second stirrer 27 movably. And. In addition, a measurement unit 29 that measures the mixed solution in the reaction vessel 17 and a cleaning nozzle 30 that cleans the inside of the reaction vessel 17 that has finished measuring the mixed solution by the measurement unit 29 are provided. The reaction container 17 cleaned by the cleaning nozzle 30 is used again, and a sample and a reagent are dispensed.

  The measurement unit 29 irradiates the reaction container 17 with light, and is expressed by, for example, absorbance or an amount of change in absorbance based on a detection signal that detects light transmitted through the mixed solution containing the standard sample in the reaction container 17. Generate standard data. In addition, based on a detection signal for irradiating the reaction container 17 with light and detecting light transmitted through the liquid mixture containing the test sample in the reaction container 17, the test data represented by the absorbance and the amount of change in absorbance are obtained. Generate.

  Although not shown in the figure, a cleaning tank is provided for cleaning the sample dispensing probe 19, the first reagent dispensing probe 21, the first stirring bar 23, the second reagent dispensing probe 25, and the second stirring bar 27, respectively. . Then, the sample dispensing probe 19 is cleaned every time the dispensing of each sample is completed. Further, the first reagent dispensing probe 21 is washed every time the dispensing of each first reagent is completed. Moreover, the 1st stirring element 23 is wash | cleaned for every completion | finish of stirring of each liquid mixture. In addition, the second reagent dispensing probe 25 is washed every time the dispensing of each second reagent is completed. Further, the second stirrer 27 is washed every time stirring of each mixed solution is completed.

  The drive unit 40 illustrated in FIG. 1 drives the sample table 12 of the analysis unit 10 to move the sample container 11. Further, the two reagent racks 14 are driven to move the reagent container 13. Further, the reaction table 18 is driven to rotate and move each reaction vessel 17. Further, the sample dispensing arm 20, the first reagent dispensing arm 22, the first stirring arm 24, the second reagent dispensing arm 26, and the second stirring arm 28 are driven, respectively, so that the sample dispensing probe 19 and the first reagent are driven. The dispensing probe 21, the first stirring bar 23, the second reagent dispensing probe 25, and the second stirring bar 27 are moved. Further, the cleaning nozzle 30 is moved up and down.

  The analysis control unit 41 operates various units of the analysis unit 10 under the control of the drive unit 40 based on the analysis parameters, avoidance parameters, dispensing information, etc. of each inspection item set by the input from the operation unit 80, Tests such as sample and reagent dispensing and mixed solution measurement are executed.

  In addition, the analysis control unit 41 performs the inspection from the start of the operations of the various units of the analysis unit 10 to the end of the dispensing, measurement, and cleaning operations in response to the input of the inspection start from the operation unit 80. The container ID for identifying each reaction container 17, the identification information for identifying the sample dispensed in the reaction container 17 identified by the container ID, and the information on the inspection item set for the sample for identifying the reagent The dispensing information is output to the data processing unit 60.

  The analysis control unit 41 sets the analysis data generated by the data processing unit 60 as an avoidance parameter among the reaction vessels 17 cleaned by the cleaning nozzle 30 every time the mixed solution is measured by the analysis unit 10. The dispensing of the reagent of the inspection item to the reaction container 17 in which the sample having the inspection item set to a value equal to or higher than the threshold value has been dispensed is stopped.

  The data processing unit 60 processes the standard data and test data generated by the measurement unit 29 of the analysis unit 10 to generate calibration data and analysis data for each inspection item, and is generated by the calculation unit 61. And a data storage unit 62 for storing standard data, analysis data, and the like. And the calculating part 61 produces | generates calibration data based on the standard data of each test | inspection item. Moreover, based on the calibration data and test data of each test item, analysis data indicated by a concentration value and an activity value is generated.

  The data storage unit 62 stores the dispensing information output from the analysis control unit 41 for each container ID of the reaction container 17 and the number of times dispensed during the inspection in order of dispensing. In addition, the calibration data generated by the calculation unit 61 is stored. Further, the analysis data generated by the calculation unit 61 is stored in association with the dispensing information related to the analysis data.

  The output unit 70 includes a printing unit 71 that prints out calibration data and analysis data generated by the calculation unit 61 of the data processing unit 60 and a display unit 72 that displays and outputs the calibration data. Then, the display unit 72 dispenses the sample in the sample container 11 into the reaction container 17 for each inspection item, and dispenses the first reagent and the second reagent in the reagent container 13 into the reaction container 17. An analysis parameter setting screen for setting the amount to be dispensed is displayed.

  The display unit 72 displays an inspection item setting screen or the like for setting identification information such as a name and ID for identifying the sample and an inspection item for each sample. In addition, to set the avoidance parameters such as the inspection item that affects and is affected, the threshold value indicating the lower limit value of the content that affects the sample in this inspection item, and the cleaning condition that can prevent the influence of the sample Display the avoidance parameter setting screen.

  The operation unit 80 includes input devices such as a keyboard, a mouse, a button, and a touch key panel, and inputs for setting analysis parameters for each test item, inputs for setting identification information and test items for each sample, and avoidance Input for setting parameters.

  The system control unit 90 includes a CPU and a storage circuit, and stores input information such as analysis parameters of each inspection item, sample identification information and inspection items, and avoidance parameters input from the operation unit 80. And based on those input information, the analysis control part 41, the data processing part 60, and the output part 70 are integrated, and the whole system is controlled.

  Next, with reference to FIG. 1 thru | or FIG. 3, operation | movement and the stop position of each reaction container 17 of the analysis part 10 are demonstrated.

FIG. 3 is a view showing an example of each stop position of each reaction vessel 17 held in the reaction table 18, and the positions of the cleaning nozzle 30 and the measurement unit 29.
Each reaction vessel 17 rotates and moves in the direction of arrow R1 every cycle time, and stops at each stop position different from that before the movement. Here, each reaction container 17 is rotationally moved in the R1 direction every cycle time by the rotational drive of the reaction table 18 at an angle θ, and is a reaction located at an angle of 90 °, for example, in the R1 direction from the position before the movement. It stops at the position of the reaction vessel 17 adjacent to the vessel 17 in the direction of the arrow R2 opposite to the R1 direction. And it stops at the same stop position every round time which is longer than one cycle time.

  Among the stop positions, there is a cleaning position W at which the reaction vessel 17 where the normal cleaning is performed once by the cleaning nozzle 30 is stopped each time the measurement of the mixed liquid by the measuring unit 29 is completed. In addition, there is a sample dispensing position Pa where the reaction container 17 where the sample in the sample container 11 is dispensed by the sample dispensing probe 19 stops. In addition, there is a first reagent dispensing position Pb at which the reaction container 17 where the first reagent in the reagent container 13 and the washing liquid are dispensed is stopped by the first reagent dispensing probe 21.

  In addition, in the stop position, the first stirrer 23 stops the reaction vessel 17 in which the mixture of the sample and the first reagent dispensed after the sample is dispensed is stopped. There is a stirring position Pc. There is also a second reagent dispensing position Pd where the reaction container 17 where the second reagent in the reagent container 13 is dispensed by the second reagent dispensing probe 25 stops. Further, there is a second stirring position Pe where the reaction vessel 17 in which the sample, the mixed solution of the first reagent and the second reagent is stirred by the second stirring bar 27 is stopped.

  The cleaning nozzle 30 includes, for example, seven first to seventh cleaning nozzles 31 to 37, and is arranged to be movable in the vertical direction at the cleaning position W by the vertical drive of the drive unit 40. Then, the normal cleaning is performed once for each round time for each reaction vessel 17 stopped at the cleaning position W. Then, the first cleaning nozzle 31 performs cleaning by sucking the mixed liquid in the reaction vessel 17 stopped at the first cleaning position W1.

  The second cleaning nozzle 32 performs cleaning by discharging, for example, an alkaline cleaning liquid into the reaction vessel 17 that stops at the second cleaning position W2 after stopping at the first cleaning position W1 and suction of the discharged alkaline cleaning liquid. The third cleaning nozzle 33 performs cleaning by discharging, for example, acidic cleaning liquid into the reaction container 17 that stops at the third cleaning position W3 after stopping at the second cleaning position W2 and suction of the discharged acidic cleaning liquid.

  The fourth cleaning nozzle 34 performs cleaning by discharging the cleaning water into the reaction vessel 17 that stops at the fourth cleaning position W4 after stopping at the third cleaning position W3 and suction of the discharged cleaning water. The fifth cleaning nozzle 35 performs cleaning by discharging the cleaning water into the reaction vessel 17 stopped at the fifth cleaning position W5 after stopping at the fourth cleaning position W4 and suctioning the discharged cleaning water.

  Further, the sixth cleaning nozzle 36 performs cleaning by suction of the cleaning water remaining in the reaction vessel 17 that stops at the sixth cleaning position W6 after stopping at the fifth cleaning position W5. In addition, the seventh cleaning nozzle 37 performs cleaning by further suction of the cleaning water remaining in the reaction container 17 stopped at the seventh cleaning position W7 after stopping at the sixth cleaning position W6.

  The measurement unit 29 includes a light source and a detector arranged across the inner and outer circumferences of each reaction container 17, and irradiates each reaction container 17 that passes through the measurement position Pm with each rotation of the reaction table 18. Then, the light transmitted through the liquid mixture containing the standard sample and the test sample in each reaction vessel 17 is detected, and standard data and test data expressed by absorbance are generated.

  Next, the avoidance parameter setting screen displayed on the display unit 72 will be described with reference to FIGS. 1 to 4.

  FIG. 4 is a diagram illustrating an example of the avoidance parameter setting screen displayed on the display unit 72. The avoidance parameter setting screen 73 includes “items”, “values”, “cleaning times”, and “items” for setting avoidance parameters in the columns “1” to “9” and the columns “1” to “9”. And “Special Cleaning” column.

  In the “Item” column, there is an inspection item showing a high value in the affected sample, and after the sample is dispensed, the first normal cleaning by the cleaning nozzle 30 is performed. In the container 17, an inspection item that is affected such that the analysis data generated by the measurement performed by dispensing the sample and the reagent is out of the allowable error range is set. In the “1” column, “B” indicating that the inspection item B is selected and set from the inspection items for which the analysis parameter is set is displayed.

  The “value” column includes “items” included in the affected sample when the analysis data of the inspection item set in the “item” column is affected by only one normal cleaning by the cleaning nozzle 30. The threshold value indicating the lower limit value of the content of the inspection item component set in the column “is set. In the “1” column, “UL” indicating that the threshold value is the value UL is displayed.

  In at least one of the fields “Number of cleanings” or “Special cleaning”, a sample whose analysis data set in the “Item” column is equal to or greater than the threshold value set in the “Value” column is dispensed. The cleaning conditions are set so that the sample can be washed out from the reaction vessel 17 thus prepared.

  In the “wash count” column, the sample from the reaction container 17 into which the analysis data of the inspection item set in the “item” column is equal to or greater than the threshold set in the “value” column is dispensed. Is set to 2 or more as the number of normal washings that can be washed off when the washing cannot be washed out by the first normal washing. In the “1” column, “2” indicating that the number of normal washings that can be washed out is two is displayed.

  In the “special cleaning” column, a sample in which the analysis data of the inspection item set in the “item” column is equal to or greater than the threshold value set in the “value” column is dispensed by the cleaning nozzle 30. It is set when the cleaning liquid in the reagent container 13 held in the reagent rack 14 by the first reagent dispensing probe 21 is dispensed to the reaction container 17 that has been subjected to the normal washing for the first time. In the “1” column, since “2” or more is set in the “washing frequency” column, “0” indicating that the cleaning liquid is not dispensed into the reaction container 17 is displayed.

  When “1” is displayed in the “special cleaning” column, for example, “1” indicating that the cleaning liquid is dispensed into the reaction vessel 17 can be set in the “special cleaning” column. . Then, by putting a dedicated cleaning liquid having a strong cleaning power with respect to the inspection item component set in the “Item” column in the reagent container 13, the reaction container 17 into which the cleaning liquid has been dispensed is cleaned. It is possible to perform stronger special cleaning over a longer time than the cleaning by the cleaning nozzle 30 until the position W is reached. The reaction container 17 that has been cleaned with this cleaning liquid can be used as a reaction container 17 that can be measured by dispensing a sample and a reagent.

  In addition, when “2” is displayed in the “Number of times of cleaning” column and “1” is displayed in the “Special cleaning” column, the cleaning conditions set in the “Special cleaning” column have priority. Special cleaning will be performed. In addition, even when “2” is displayed in the “wash count” column and “1” is displayed in the “special wash” column, the reagent container 13 containing the cleaning liquid is held in the reagent rack 14. Otherwise, cleaning is performed in accordance with the cleaning conditions displayed in the “Number of times of cleaning” column.

  The analysis control unit 41 includes avoidance parameters displayed on the avoidance parameter setting screen 73 of the display unit 72, identification information of each sample to be inspected, inspection items set for the sample, and a data storage unit 62 of the data processing unit 60. Whether or not each reaction vessel 17 that has been normally cleaned by the cleaning nozzle 30 can be used is determined for each cycle time based on the analysis data, dispensing information, and the like stored in the table.

  FIG. 5 is a flowchart showing an example of a procedure for determining whether or not each reaction vessel 17 can be used.

  The analysis control unit 41 assigns a sample to be dispensed to, for example, the reaction container 17 at the seventh cleaning position W7 after the normal cleaning (current normal cleaning) is completed by the cleaning nozzle 30 at the cleaning position W. Then, based on the inspection item set for the assigned sample, the determination of whether or not the reaction container 17 to be determined at the seventh cleaning position W7 can be used is started (step S10).

  When the inspection item B is set for the current sample assigned to the determination target reaction container 17 (Yes in Step S11), the analysis control unit 41 proceeds to Step S12. Further, when the inspection item B is not set in the current sample assigned to the determination target reaction container 17 (No in Step S11), the process proceeds to Step S15.

  When the inspection item B is set in the previous sample dispensed to the reaction container 17 to be determined after the previous normal cleaning performed one round time after “Yes” in Step S11 (Step S12) Yes), the process proceeds to step S13. If the inspection item B is not set in the previous sample dispensed in the reaction container 17 to be determined (No in step S12), the process proceeds to step S15.

  After the “yes” in step S12, if the analysis data of the inspection item B set in the previous sample is equal to or greater than the value UL (yes in step S13), the analysis was performed after the previous sample was dispensed. It is determined that the reaction container 17 to be determined cannot be used for the inspection item B by only one normal cleaning. Then, the process proceeds to step S14. If the analysis data of the inspection item B set for the previous sample is less than the value UL (No in step S13), the process proceeds to step S15.

  After “Yes” in Step S13, when inspection items other than the inspection item B are set for the current sample (Yes in Step S14), the process proceeds to Step S15. If no inspection item other than the inspection item B is set in the current sample (No in step S14), the process proceeds to step S16.

  After “No” in Step S11, “No” in Step S12, “No” in Step S13, or “Yes” in Step S14, the analysis control unit 41 uses the reaction container 17 to be determined for the current sample. Is determined to be possible (step S15).

  However, after “No” in Step S11, “No” in Step S12, or “No” in Step S13, the reaction container 17 to be determined can be used for all the inspection items set for the current sample. It is determined that Further, after “Yes” in step S14, it is determined that the reaction container 17 to be determined can be used for the inspection items other than the inspection item B set for the current sample.

  After “No” in Step S14, the analysis control unit 41 determines that the determination target reaction vessel 17 cannot be used for the current sample (Step S16).

  After step S15 or step S16, the analysis control unit 41 ends the determination of the reaction container 17 to be determined (step S17).

  The analysis control unit 41 sets the current sample and any of the samples set in this sample to the determination target reaction container 17 determined to be usable after “No” in Step S11, Step S12, or Step S13 of FIG. Let the reagent for the test item be dispensed. Moreover, the reagent of the test item other than the current sample and the test item B set for this sample is dispensed to the reaction container 17 to be determined that is determined to be usable after “Yes” in step S14.

  In this way, by stopping the use of the reaction container 17 that has been normally cleaned by the cleaning nozzle 30 for the inspection item B, it is possible to prevent the analysis data of the inspection item B from being deteriorated. Then, by causing the reaction container 17 that has been normally cleaned by the cleaning nozzle 30 to dispense the reagent of the inspection item other than the inspection item B, it is possible to prevent a decrease in throughput.

  In addition, the analysis control unit 41 dispenses the current sample and the reagent of the test item B set in this sample to the reaction container 17 to be determined that is determined to be unusable after “No” in Step S14. Stop. Thus, by stopping dispensing of the reagent of the inspection item B to the reaction container 17 determined to be unusable, deterioration of the analysis data of the inspection item B can be prevented in advance.

  Here, if the cleaning liquid is set in the “special cleaning” field on the avoidance parameter setting screen 73, the cleaning liquid is distributed to the reaction container 17 to be determined that is determined to be unusable after “No” in step S14. I will let you note. In this way, by injecting the cleaning liquid into the reaction vessel 17 determined to be unusable, the affected sample can be washed away.

  Since “2” is displayed in the “wash count” column of the avoidance parameter setting screen 73, the reaction container 17 into which the sample whose analysis data of the inspection item B is equal to or greater than the value UL is dispensed is shown. After the first normal cleaning, if the sample whose analysis data for the inspection item B is equal to or greater than the value UL is not dispensed before the second normal cleaning, the two normal cleanings have an effect. Since the sample to be given can be washed off, it can be used for the inspection item B after the second normal cleaning.

  If the analysis control unit 41 determines that the determination target reaction container 17 cannot be used for the current sample after “No” in step S14, the analysis control unit 41 determines that the determination target reaction container 17 is not used. It is determined whether or not the sample to be allocated next to the current sample can be dispensed. When the inspection item other than the inspection item B is set for the sample to be assigned next, the sample to be assigned next to the reaction container 17 to be determined and the reagent for the inspection item other than the inspection item B set for the sample are added. Let them dispense.

  In this way, by dispensing the sample assigned next to the reaction container 17 that has been normally cleaned by the cleaning nozzle 30 and the reagent of the inspection item other than the inspection item B set in this sample, the throughput is reduced. Can be prevented.

  If the analysis control unit 41 determines that the determination target reaction vessel 17 cannot be used for the current sample after “No” in step S14, the analysis control unit 41 further determines that the determination target is to be determined at the next cycle time. The present sample is assigned to the reaction vessel 17 and the determination is performed by executing steps S12 to S16.

  In addition, it is not limited to the said embodiment, The reaction by which the washing | cleaning nozzle 30 performed the 1st time after dispensing of the sample in which the inspection item B used as the value more than value UL was performed was performed. You may carry out so that the reagent of test | inspection item B and the sample in which this test | inspection item B was set may be dispensed to the container 17. FIG. In this case, an error flag is added to the analysis data obtained by the measurement of the mixed solution with the reagent of the test item B, and the data is stored in the data storage unit 62 and output to the output unit 70.

  According to the embodiment described above, after the sample in which the inspection item B having the analysis data equal to or larger than the value UL set as the avoidance parameter is dispensed, the cleaning nozzle 30 performs the first cleaning. The dispensing of the sample into the reaction container 17 and the reagent of the inspection item B set in this sample can be stopped. Thereby, deterioration of the analysis data due to the influence of the sample can be prevented in advance.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

DESCRIPTION OF SYMBOLS 10 Analysis part 17 Reaction container 30 Washing nozzle 60 Data processing part 41 Analysis control part

Claims (5)

In an automatic analyzer that dispenses each sample and a reagent for each inspection item set in the sample into a reaction container, and generates analysis data by measuring a mixed solution of the sample and the reagent in the reaction container.
A cleaning nozzle for cleaning the reaction container every time the measurement of the mixed liquid is completed;
Of the reaction containers cleaned by the cleaning nozzle, the inspection items to the reaction containers in which the sample in which the inspection items whose analysis data is equal to or greater than a preset threshold value are dispensed are performed. An automatic analyzer comprising an analysis control unit that stops dispensing of reagents.   The analysis control unit is configured to supply a reagent for the inspection item to the reaction container that has been first washed by the washing nozzle after dispensing the sample in which the inspection item having a value equal to or greater than the threshold is set. The automatic analyzer according to claim 1, wherein the dispensing is stopped.   The analysis control unit performs the inspection on a reaction container that has been preliminarily washed a plurality of times by the washing nozzle after dispensing a sample in which an inspection item having a value equal to or greater than the threshold is set. The automatic analyzer according to claim 2, wherein the reagent of the item is dispensed.   The automatic analysis according to claim 1, wherein the analysis control unit causes a reagent of an inspection item different from the inspection item to be dispensed to a reaction container that stops dispensing of the reagent of the inspection item. Analysis equipment.   The automatic analysis apparatus according to claim 1, wherein the analysis control unit causes the cleaning liquid to be dispensed into a reaction container that stops dispensing of the reagent of the inspection item.

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