JP2017071603A - ジヒドロチアジンまたはジヒドロオキサジン誘導体を含有する医薬組成物 - Google Patents

ジヒドロチアジンまたはジヒドロオキサジン誘導体を含有する医薬組成物 Download PDF

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JP2017071603A
JP2017071603A JP2016198584A JP2016198584A JP2017071603A JP 2017071603 A JP2017071603 A JP 2017071603A JP 2016198584 A JP2016198584 A JP 2016198584A JP 2016198584 A JP2016198584 A JP 2016198584A JP 2017071603 A JP2017071603 A JP 2017071603A
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JP2016198584A
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JP2017071603A5 (enExample
Inventor
和雄 駒野
Kazuo Komano
和雄 駒野
中原　健二
Kenji Nakahara
健二 中原
元太 只野
Genta Tadano
元太 只野
光記 渕野
Mitsuki Fuchino
光記 渕野
兼一 日下部
Kenichi Kusakabe
兼一 日下部
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Shionogi and Co Ltd
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Shionogi and Co Ltd
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Publication of JP2017071603A publication Critical patent/JP2017071603A/ja
Publication of JP2017071603A5 publication Critical patent/JP2017071603A5/ja
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016198584A 2015-10-09 2016-10-07 ジヒドロチアジンまたはジヒドロオキサジン誘導体を含有する医薬組成物 Pending JP2017071603A (ja)

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JP2015200650 2015-10-09
JP2015200650 2015-10-09

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JP2017071603A true JP2017071603A (ja) 2017-04-13
JP2017071603A5 JP2017071603A5 (enExample) 2019-11-14

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JP2016198584A Pending JP2017071603A (ja) 2015-10-09 2016-10-07 ジヒドロチアジンまたはジヒドロオキサジン誘導体を含有する医薬組成物

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019208693A1 (en) 2018-04-27 2019-10-31 Shionogi & Co., Ltd. Tetrahydropyranooxazine derivatives having selective bace1 inhibitory activity
WO2020009179A1 (en) * 2018-07-06 2020-01-09 Shionogi & Co., Ltd. Fused heterocyclic derivatives having selective bace1 inhibitory activity
EP2511268B2 (en) † 2009-12-11 2021-02-17 Shionogi & Co., Ltd. Oxazine derivative

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008133273A1 (ja) * 2007-04-24 2008-11-06 Shionogi & Co., Ltd. アルツハイマー症治療用医薬組成物
WO2012147762A1 (ja) * 2011-04-26 2012-11-01 塩野義製薬株式会社 ピリジン誘導体およびそれを含有するｂａｃｅ１阻害剤
WO2013110622A1 (en) * 2012-01-26 2013-08-01 F. Hoffmann-La Roche Ag Fluoromethyl-5,6-dihydro-4h-[1,3]oxazines
JP2013216666A (ja) * 2007-04-24 2013-10-24 Shionogi & Co Ltd 環式基で置換されたアミノジヒドロチアジン誘導体
WO2014166906A1 (en) * 2013-04-11 2014-10-16 F. Hoffmann-La Roche Ag Bace1 inhibitors

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008133273A1 (ja) * 2007-04-24 2008-11-06 Shionogi & Co., Ltd. アルツハイマー症治療用医薬組成物
JP2013216666A (ja) * 2007-04-24 2013-10-24 Shionogi & Co Ltd 環式基で置換されたアミノジヒドロチアジン誘導体
WO2012147762A1 (ja) * 2011-04-26 2012-11-01 塩野義製薬株式会社 ピリジン誘導体およびそれを含有するｂａｃｅ１阻害剤
WO2013110622A1 (en) * 2012-01-26 2013-08-01 F. Hoffmann-La Roche Ag Fluoromethyl-5,6-dihydro-4h-[1,3]oxazines
WO2014166906A1 (en) * 2013-04-11 2014-10-16 F. Hoffmann-La Roche Ag Bace1 inhibitors

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
HILPERT,H. ET AL.: "B-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzhei", JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, no. 10, JPN6020035652, 2013, pages 3980 - 3995, ISSN: 0004412721 *
REGISTRY（STN）, JPN7020002936, 30 October 2014 (2014-10-30), ISSN: 0004349376 *
REGISTRY（STN）, JPN7020002937, 30 October 2014 (2014-10-30), ISSN: 0004349377 *
REGISTRY（STN）, JPN7020002938, 30 October 2014 (2014-10-30), ISSN: 0004349378 *
REGISTRY（STN）, JPN7020002939, 30 October 2014 (2014-10-30), ISSN: 0004349379 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2511268B2 (en) † 2009-12-11 2021-02-17 Shionogi & Co., Ltd. Oxazine derivative
WO2019208693A1 (en) 2018-04-27 2019-10-31 Shionogi & Co., Ltd. Tetrahydropyranooxazine derivatives having selective bace1 inhibitory activity
KR20210003872A (ko) 2018-04-27 2021-01-12 시오노기 앤드 컴파니, 리미티드 선택적 bace1 억제 활성을 갖는 테트라하이드로피라노옥사진 유도체
US11629154B2 (en) 2018-04-27 2023-04-18 Shionogi & Co., Ltd. Tetrahydropyranooxazine derivatives having selective BACE1 inhibitory activity
WO2020009179A1 (en) * 2018-07-06 2020-01-09 Shionogi & Co., Ltd. Fused heterocyclic derivatives having selective bace1 inhibitory activity

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