|
US4352883A
(en)
|
1979-03-28 |
1982-10-05 |
Damon Corporation |
Encapsulation of biological material
|
|
US4353888A
(en)
|
1980-12-23 |
1982-10-12 |
Sefton Michael V |
Encapsulation of live animal cells
|
|
US4407957A
(en)
|
1981-03-13 |
1983-10-04 |
Damon Corporation |
Reversible microencapsulation of a core material
|
|
US5169637A
(en)
|
1983-03-24 |
1992-12-08 |
The Liposome Company, Inc. |
Stable plurilamellar vesicles
|
|
CA1237671A
(en)
|
1983-08-01 |
1988-06-07 |
Michael W. Fountain |
Enhancement of pharmaceutical activity
|
|
US4762915A
(en)
|
1985-01-18 |
1988-08-09 |
Liposome Technology, Inc. |
Protein-liposome conjugates
|
|
IL79289A
(en)
|
1985-07-05 |
1992-01-15 |
Whitehead Biomedical Inst |
Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus
|
|
US4883666A
(en)
|
1987-04-29 |
1989-11-28 |
Massachusetts Institute Of Technology |
Controlled drug delivery system for treatment of neural disorders
|
|
ATE117375T1
(de)
|
1987-09-11 |
1995-02-15 |
Whitehead Biomedical Inst |
Transduktionsveränderte fibroblasten und ihre anwendung.
|
|
US5158881A
(en)
|
1987-11-17 |
1992-10-27 |
Brown University Research Foundation |
Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
|
|
US5283187A
(en)
|
1987-11-17 |
1994-02-01 |
Brown University Research Foundation |
Cell culture-containing tubular capsule produced by co-extrusion
|
|
US5156844A
(en)
|
1987-11-17 |
1992-10-20 |
Brown University Research Foundation |
Neurological therapy system
|
|
US5106627A
(en)
|
1987-11-17 |
1992-04-21 |
Brown University Research Foundation |
Neurological therapy devices
|
|
US4892538A
(en)
|
1987-11-17 |
1990-01-09 |
Brown University Research Foundation |
In vivo delivery of neurotransmitters by implanted, encapsulated cells
|
|
DE3829752A1
(de)
|
1988-09-01 |
1990-03-22 |
Akzo Gmbh |
Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
|
|
DE3829766A1
(de)
|
1988-09-01 |
1990-03-22 |
Akzo Gmbh |
Verfahren zur herstellung von membranen
|
|
US5082670A
(en)
|
1988-12-15 |
1992-01-21 |
The Regents Of The University Of California |
Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
|
|
US5185154A
(en)
|
1989-02-02 |
1993-02-09 |
Liposome Technology, Inc. |
Method for instant preparation of a drug containing large unilamellar vesicles
|
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
|
US5084350A
(en)
|
1990-02-16 |
1992-01-28 |
The Royal Institution For The Advance Of Learning (Mcgill University) |
Method for encapsulating biologically active material including cells
|
|
US5618531A
(en)
|
1990-10-19 |
1997-04-08 |
New York University |
Method for increasing the viability of cells which are administered to the brain or spinal cord
|
|
US5219990A
(en)
|
1991-01-28 |
1993-06-15 |
Biogen, Inc. |
Papillomavirus e2 trans-activation repressors
|
|
ATE156344T1
(de)
|
1991-04-25 |
1997-08-15 |
Univ Brown Res Found |
Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte
|
|
DK0639225T3
(da)
|
1992-04-30 |
2003-02-17 |
Innogenetics Nv |
Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi
|
|
CA2150803C
(en)
|
1992-12-02 |
2006-01-31 |
Henry Auer |
Controlled release growth hormone containing microspheres
|
|
US5512600A
(en)
|
1993-01-15 |
1996-04-30 |
Massachusetts Institute Of Technology |
Preparation of bonded fiber structures for cell implantation
|
|
NZ269041A
(en)
|
1993-06-23 |
1998-02-26 |
Univ Brown Res Found |
Implantable encapsulation device having a cell-tight dry seal at an opening thereof
|
|
SG48813A1
(en)
|
1993-08-12 |
1998-05-18 |
Cytotherapeutics Inc |
Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
|
|
EP0804249A2
(en)
|
1994-03-15 |
1997-11-05 |
Brown University Research Foundation |
Polymeric gene delivery system
|
|
US5550050A
(en)
|
1994-04-15 |
1996-08-27 |
Cytotherapeutics, Inc. |
Method for implanting encapsulated cells in a host
|
|
US5656465A
(en)
|
1994-05-04 |
1997-08-12 |
Therion Biologics Corporation |
Methods of in vivo gene delivery
|
|
PT779806E
(pt)
|
1994-09-09 |
2001-02-28 |
Takeda Chemical Industries Ltd |
Preparacao de libertacao sustentada contendo um sal metalico de um peptido
|
|
PT831787E
(pt)
|
1995-06-07 |
2002-02-28 |
Alkermes Inc |
Composicao para libertacao sustentada da hormona de crescimento humano
|
|
US5677158A
(en)
|
1995-06-07 |
1997-10-14 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
ZA965368B
(en)
|
1995-07-14 |
1997-01-14 |
Novo Nordisk As |
A pharmaceutical formulation
|
|
US5904144A
(en)
|
1996-03-22 |
1999-05-18 |
Cytotherapeutics, Inc. |
Method for treating ophthalmic diseases
|
|
US6027721A
(en)
|
1996-05-20 |
2000-02-22 |
Cytotherapeutics, Inc. |
Device and method for encapsulated gene therapy
|
|
US6054142A
(en)
|
1996-08-01 |
2000-04-25 |
Cyto Therapeutics, Inc. |
Biocompatible devices with foam scaffolds
|
|
US6303136B1
(en)
|
1998-04-13 |
2001-10-16 |
Neurotech S.A. |
Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
|
|
US6683058B1
(en)
|
1998-04-15 |
2004-01-27 |
Regents Of The University Of California |
Methods for therapy of neurodegenerative disease of the brain
|
|
WO1999061066A2
(en)
|
1998-05-27 |
1999-12-02 |
Avigen, Inc. |
Convection-enhanced delivery of aav vectors
|
|
US20020055467A1
(en)
*
|
1998-07-06 |
2002-05-09 |
Johansen Teit E. |
Novel neurotrophic factors
|
|
US6361771B1
(en)
|
1999-04-06 |
2002-03-26 |
Neurotech S.A. |
ARPE-19 as a platform cell line for encapsulated cell-based delivery
|
|
AU7452300A
(en)
|
1999-10-01 |
2001-05-10 |
Kyowa Hakko Kogyo Co. Ltd. |
Shear stress-response dna
|
|
EP1233779A2
(en)
|
1999-11-30 |
2002-08-28 |
Innogenetics N.V. |
New uses of suppressive macrophage activation factors
|
|
WO2001055301A2
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
WO2001055440A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
CA2399776A1
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
CA2403901A1
(en)
|
2000-05-02 |
2001-11-08 |
Human Genome Sciences, Inc. |
29 human secreted proteins
|
|
US20020037281A1
(en)
|
2000-05-26 |
2002-03-28 |
Davidson Beverly L. |
Methods of transducing neural cells using lentivirus vectors
|
|
US6555674B2
(en)
|
2000-08-09 |
2003-04-29 |
Nsgene A/S |
JeT promoter
|
|
CN1525866B
(zh)
|
2001-03-28 |
2013-05-29 |
比奥根艾迪克Ma公司 |
神经胚活素多肽的治疗作用
|
|
WO2003066877A2
(en)
|
2001-12-21 |
2003-08-14 |
Diadexus, Inc. |
Compositions and methods relating to hepatic specific genes and proteins
|
|
WO2004035732A2
(en)
|
2002-08-29 |
2004-04-29 |
Five Prime Therapeutics, Inc. |
Human polypeptides encoded by polynucleotides and methods of their use
|
|
US20050203142A1
(en)
*
|
2002-10-24 |
2005-09-15 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
|
|
WO2004079014A2
(en)
|
2003-03-04 |
2004-09-16 |
Arcturus Bioscience, Inc. |
Signatures of er status in breast cancer
|
|
AU2005229434B2
(en)
*
|
2004-03-30 |
2010-09-30 |
Nsgene A/S |
Therapeutic use of a growth factor, NsG33
|
|
ES2375481T3
(es)
|
2004-03-30 |
2012-03-01 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Anticuerpos biespecíficos para elegir como diana células que participan en reacciones de tipo alérgico, composiciones y usos de los mismos.
|
|
US20070161696A1
(en)
*
|
2004-04-23 |
2007-07-12 |
Zeldis Jerome B |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
|
WO2006110593A2
(en)
*
|
2005-04-07 |
2006-10-19 |
Macrogenics, Inc. |
Biological targets for the diagnosis, treatment and prevention of cancer
|
|
EP1883446B8
(en)
|
2005-05-17 |
2017-11-15 |
Gloria Therapeutics Sarl |
An implantable therapy system for treating a living being with an active factor
|
|
EP1940471A1
(en)
|
2005-10-28 |
2008-07-09 |
NsGene A/S |
IMPLANTABLE BIOCOMPATIBLE IMMtTNOISOLATORY VEHICLE FOR DELIVERY OF GDNF
|
|
US20100323000A1
(en)
|
2006-02-24 |
2010-12-23 |
Neopharm, Inc. |
Method and process for preparing cardiolipin
|
|
TWI501774B
(zh)
*
|
2006-02-27 |
2015-10-01 |
Biogen Idec Inc |
神經性病症之治療
|
|
US7960345B2
(en)
*
|
2007-05-02 |
2011-06-14 |
Snu R&Db Foundation |
Angiogenesis inhibitor comprising meteorin as an active ingredient
|
|
KR100823156B1
(ko)
*
|
2007-05-02 |
2008-04-22 |
재단법인서울대학교산학협력재단 |
메테오린을 유효성분으로 포함하는 혈관신생 억제제
|
|
WO2009069764A1
(ja)
*
|
2007-11-30 |
2009-06-04 |
National University Corporation Chiba University |
オピオイド鎮痛剤
|
|
DK2195013T3
(da)
*
|
2008-07-24 |
2012-02-06 |
Nsgene As |
Terapeutisk anvendelse af en vækstfaktor, METRNL
|
|
JP5937353B2
(ja)
*
|
2008-08-19 |
2016-06-22 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ |
冷感−メントール受容体拮抗剤
|
|
CN102202677A
(zh)
*
|
2008-09-03 |
2011-09-28 |
阿尔伯维塔公司 |
治疗疼痛的活性剂和方法
|
|
TW201031650A
(en)
*
|
2008-12-02 |
2010-09-01 |
Organon Nv |
1-(biphenyl-4-ylmethyl)imidazolidine-2,4-dione
|
|
WO2012041328A1
(en)
|
2010-10-01 |
2012-04-05 |
Nsgene A/S |
Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
|