JP2017000729A - 複数相鉄鋼を含むエンドプロテーゼ - Google Patents
複数相鉄鋼を含むエンドプロテーゼ Download PDFInfo
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- JP2017000729A JP2017000729A JP2016093451A JP2016093451A JP2017000729A JP 2017000729 A JP2017000729 A JP 2017000729A JP 2016093451 A JP2016093451 A JP 2016093451A JP 2016093451 A JP2016093451 A JP 2016093451A JP 2017000729 A JP2017000729 A JP 2017000729A
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- endoprosthesis
- steel
- phase steel
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- 229910000831 Steel Inorganic materials 0.000 title claims description 51
- 239000010959 steel Substances 0.000 title claims description 51
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 33
- 229910052742 iron Inorganic materials 0.000 claims abstract description 16
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- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
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- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical class [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
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Images
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Abstract
Description
この出願は、2009年12月31日に出願された米国仮出願番号61/291,497に対する優先権を主張する。
本発明は、エンドプロテーゼの分野、特に直径方向に延伸可能なエンドプロテーゼの分野に関する。
様々な種類の金属材料は、これまで埋め込み型医療デバイスに用いられてきている。種類316L又は316LVMのステンレス鋼、コバルト−クロム合金、工業用純チタン、及びチタン合金は、埋め込み可能なデバイスに用いられる典型的な材料である。埋め込みの環境及び方法は、特定の生体適合性及び材料特性を有する特定の原料の使用を要求する。これらの材料は、特殊用途のために、典型的に、必須の物理学的特性、例えば引張強度、疲労抵抗、弾性収縮力、及び降伏強度を保有する。
第一の実施形態は、複数相(multi−phase)(複数相(multiple phase))鉄ステンレス鋼からなるエンドプロテーゼ(即ち、体の内部に設置されるプロテーゼ)を提供する。複数相鉄ステンレス鋼(先進的高強度鋼(Advanced High Strength steel)、又はAHSSとも称される)は、微細構造中に1超の相(例えば、オーステナイト、フェライト、ベイナイト、又はマルテンサイト)を含む任意の鉄鋼として定義される。複数相鉄ステンレス鋼としては、例えば、二相(dual phase)、複合的な相(微細構造中に2超の相が存在する)、二重(duplex)、TRIP、TWIP(双晶誘起塑性(Twining Induced Plasticity))、及びQ&P(焼入れ分配(Quenched and Partitioned))の鋼が挙げられる。
図1は、L605コバルトクロム合金、二相(dual phase)鋼、TRIP鋼、及び316L又は316LVMステンレス鋼の典型的な特性を比較した応力−歪み曲線を示す。図に示されるように、L605は、比較的高い降伏強度(YS)100及び高い最大引張強度(UTS)108を有した一方で、316L又は316LVMは、低い降伏強度106及び低い最大引張強度114を有した。二相(dual phase)鋼(102)及びTRIP鋼(104)は、典型的に、成形性及び延伸の容易性を増加させるL605(100)のそれよりも低い降伏強度を有する。二相(dual phase)鋼(102)及びTRIP鋼(104)の最大引張強度が、316L又は316LVM(114)の最大引張強度よりも高いことは、注目に値する。
図8は、複数相鉄鋼から作られ得る典型的な種類のバルーン延伸可能な管状エンドプロテーゼ80を示す。明確にするために、マンドレル(mandrel)又は他の円筒形態がデバイスの管状形態の内部に挿入される場合に、かかるデバイスが一般的に観察者見えるように、管状形態(観察者から最も遠い)の背面は除かれて、観察者に最も近いデバイスの側面のみは、図8に示される。図8は、カテーテルバルーンでの続く部分的な直径方向の延伸のように見える、エンドプロテーゼ80を示す。この種類のデバイスは、厚さ6.35mmの鋼プレートの形態で、二重(Duplex)グレードS2205(Sandmeyer Steel Co.,Philadelphia PAから入手可能である)を用いて製造された。容認された鋼プレートは、以下の特性を有する:
845MPaのUTS
644MPaの0.2%YS
29の伸長(%)
56.4%のオーステナイト及び43.6%のフェライト体積率
オーステナイト及びフェライトの体積率は、銅源を用いたX線回折技術を用いて測定された。測定は、プレートが横断面である場合、プレートの中心で行われた。
781MPaのUTS
485MPaの0.2%YS
34の伸長(%)
216GPaの引張応力
41.4%のオーステナイト及び58.6%のフェライト体積率
316LVMの機械的特性は、以下である:
661MPaのUTS
340MPaの0.2%YS
53の伸長(%)
126GPaの引張応力。
試験された比較のL605サンプルの機械的特性は、以下である:
1079MPaのUTS
567MPaの0.2%YS
56の伸長(%)
235GPaの引張応力。
Claims (20)
- 鉄を含有する複数相鋼を含む、エンドプロテーゼ。
- 前記複数相鋼が二相(dual phase)鋼である、請求項1に記載のエンドプロテーゼ。
- 前記複数相鋼が複合的な相鋼である、請求項1に記載のエンドプロテーゼ。
- 前記複数相鋼が二重(duplex)鋼である、請求項1に記載のエンドプロテーゼ。
- 前記複数相鋼が変態誘起塑性鋼である、請求項1に記載のエンドプロテーゼ。
- 前記複数相鋼が双晶誘起塑性鋼である、請求項1に記載のエンドプロテーゼ。
- 前記複数相鋼が焼入れ分配鋼である、請求項1に記載のエンドプロテーゼ。
- 直径方向に延伸可能なデバイスを含む、請求項1に記載のエンドプロテーゼ。
- バルーン延伸可能なステントを含む、請求項8に記載のエンドプロテーゼ。
- ステント・グラフトを含む、請求項9に記載のエンドプロテーゼ。
- フィルターデバイスを含む、請求項1に記載のエンドプロテーゼ。
- 歯列矯正ワイヤを含む、請求項1に記載のエンドプロテーゼ。
- 電気的圧着コネクタを含む、請求項1に記載のエンドプロテーゼ。
- 更にPTFEを含む、請求項1に記載のエンドプロテーゼ。
- 更に生体活性物質を含む、請求項1に記載のエンドプロテーゼ。
- 複数相鋼の平たいシートを所望の形状に成形するステップ、前記所望の形状を管状形態に成形するステップ、前記管状形態をバルーン型血管内送達システムに圧着するステップ、前記所望の形状を治療の領域に送達するステップ、及び治療の領域において前記所望の形状を延伸するステップを含む、エンドプロテーゼを製造する方法。
- 複数相鋼の管状形態を所望の形状に成形するステップ、前記管状形態をバルーン型血管内送達システムに圧着するステップを含む、エンドプロテーゼを製造する方法。
- 複数相鋼のワイヤを所望の管形状に成形するステップ、前記管形状をバルーン型血管内送達システムに圧着するステップ、前記所望の形状を治療の領域まで送達するステップ、及び治療の領域において前記所望の形状を延伸するステップを含む、エンドプロテーゼを製造する方法。
- 金属の表面において、圧縮残留応力を与えるために、メディアを用いて、成形されたデバイスに影響を与えるステップを更に含む、請求項18に記載の方法。
- 前記管状形態をバルーン型血管内送達システムに圧着する前に、成形されたデバイスを電解研磨するステップを更に含む、請求項18に記載の方法。
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US12/981,102 US20110160838A1 (en) | 2009-12-31 | 2010-12-29 | Endoprosthesis containing multi-phase ferrous steel |
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AU2010339451A1 (en) | 2012-08-16 |
JP6290972B2 (ja) | 2018-03-07 |
EP2519268A1 (en) | 2012-11-07 |
WO2011082280A1 (en) | 2011-07-07 |
JP2013516243A (ja) | 2013-05-13 |
CN102695529B (zh) | 2015-11-25 |
KR101901382B1 (ko) | 2018-09-27 |
AU2010339451B2 (en) | 2014-10-02 |
CA2783625C (en) | 2015-06-02 |
EP2519268B1 (en) | 2019-04-17 |
BR112012015422A2 (pt) | 2017-05-23 |
RU2012132648A (ru) | 2014-02-10 |
CN102695529A (zh) | 2012-09-26 |
KR20120123331A (ko) | 2012-11-08 |
CA2783625A1 (en) | 2011-07-07 |
ES2731371T3 (es) | 2019-11-15 |
US20110160838A1 (en) | 2011-06-30 |
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