JP2016539083A5 - - Google Patents

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Publication number
JP2016539083A5
JP2016539083A5 JP2016519326A JP2016519326A JP2016539083A5 JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5 JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5
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JP
Japan
Prior art keywords
αvβ6
her2
inhibitor
binding agent
targeted binding
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Application number
JP2016519326A
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English (en)
Japanese (ja)
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JP2016539083A (ja
JP6527508B2 (ja
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Priority claimed from PCT/EP2014/071028 external-priority patent/WO2015049280A1/en
Publication of JP2016539083A publication Critical patent/JP2016539083A/ja
Publication of JP2016539083A5 publication Critical patent/JP2016539083A5/ja
Application granted granted Critical
Publication of JP6527508B2 publication Critical patent/JP6527508B2/ja
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JP2016519326A 2013-10-01 2014-10-01 αVβ6を過剰発現する癌を治療及び診断する方法 Active JP6527508B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361885302P 2013-10-01 2013-10-01
US61/885,302 2013-10-01
PCT/EP2014/071028 WO2015049280A1 (en) 2013-10-01 2014-10-01 Methods of treating and diagnosing alpha-v-beta-6 overexpressing cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019052035A Division JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Publications (3)

Publication Number Publication Date
JP2016539083A JP2016539083A (ja) 2016-12-15
JP2016539083A5 true JP2016539083A5 (enExample) 2017-11-09
JP6527508B2 JP6527508B2 (ja) 2019-06-05

Family

ID=51655742

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016519326A Active JP6527508B2 (ja) 2013-10-01 2014-10-01 αVβ6を過剰発現する癌を治療及び診断する方法
JP2019052035A Pending JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019052035A Pending JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Country Status (7)

Country Link
US (2) US20160319032A1 (enExample)
EP (1) EP3052523B1 (enExample)
JP (2) JP6527508B2 (enExample)
CN (1) CN106232625B (enExample)
AU (1) AU2014331118B2 (enExample)
CA (1) CA2925057A1 (enExample)
WO (1) WO2015049280A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10441654B2 (en) 2014-01-24 2019-10-15 Children's Hospital Of Eastern Ontario Research Institute Inc. SMC combination therapy for the treatment of cancer
JP7107839B2 (ja) * 2015-12-11 2022-07-27 ルプレヒト-カールス-ウニベルジテート ハイデルベルク Pkm2モジュレーター及びhmgb1の組合せ製剤
AU2017269335B2 (en) 2016-05-26 2021-07-01 Recurium Ip Holdings, Llc EGFR inhibitor compounds
MY201852A (en) * 2016-06-14 2024-03-20 Merck Sharp & Dohme Llc Anti-coagulation factor xi antibodies
CN110291089B (zh) 2017-01-17 2022-05-27 海帕瑞吉尼克斯股份有限公司 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂
CN106950371B (zh) * 2017-02-17 2019-03-08 张灏 Pd-l1、cdk5和ctla4中的至少一种在制备肿瘤诊断试剂盒中的用途
KR102630070B1 (ko) * 2017-03-31 2024-01-26 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 알파-v 베타-3-양성인 암 줄기 세포(csc)를 표적화하여 사멸시키고 약물 내성 암을 치료하기 위한 조성물 및 방법
CN109265551B (zh) * 2018-09-25 2020-09-15 华东师范大学 Cd38抗体、嵌合抗原受体和药物
CA3116412A1 (en) 2018-10-31 2020-05-07 Humanigen, Inc. Materials and methods for treating cancer
WO2020092839A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
EP3873540A4 (en) 2018-10-31 2022-07-27 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
EP3955943A4 (en) * 2019-02-22 2023-10-25 Candel Therapeutics, Inc. Gmci and ddri combination therapy for treating cancer
IL293195A (en) 2019-12-05 2022-07-01 Seagen Inc Anti-avb6 antibodies and antibody-drug conjugates
US11579085B2 (en) * 2020-07-17 2023-02-14 Robert Bosch Gmbh Sensing devices
CN114195893A (zh) * 2020-09-17 2022-03-18 百奥泰生物制药股份有限公司 抗整联蛋白抗体或抗原结合片段及其应用
CN118440187A (zh) * 2023-01-05 2024-08-06 郴州市第一人民医院 一种抗SARS-like冠状病毒和/或新冠突变株的广谱抗体及其应用
CN117603348B (zh) * 2023-11-24 2024-08-09 优睿赛思(武汉)生物科技有限公司 抗新型冠状病毒s蛋白的全人源化抗体及其应用
EP4595981A1 (en) * 2024-02-01 2025-08-06 Jack Elands Antibody-drug conjugates comprising an anti-integrin v 6 binding antibody
WO2025163120A1 (en) 2024-02-01 2025-08-07 Adcytherix Sas ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-INTEGRIN ΑVβ6 BINDING ANTIBODY

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1646160A (zh) * 2002-03-13 2005-07-27 拜奥根Idec马萨诸塞公司 抗αvβ6抗体
CN102875681A (zh) * 2005-07-08 2013-01-16 拜奥根Idec马萨诸塞公司 抗-αvβ6抗体及其用途
KR20090039739A (ko) * 2006-08-03 2009-04-22 아스트라제네카 아베 αVβ6에 대해 작용하는 항체 및 그의 용도
US9493566B2 (en) * 2012-02-17 2016-11-15 Seattle Genetics, Inc. Antibodies to integrin AVB6 and use of same to treat cancer

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