JP2016539083A5 - - Google Patents

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Publication number
JP2016539083A5
JP2016539083A5 JP2016519326A JP2016519326A JP2016539083A5 JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5 JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5
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JP
Japan
Prior art keywords
αvβ6
her2
inhibitor
binding agent
targeted binding
Prior art date
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JP2016519326A
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English (en)
Japanese (ja)
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JP6527508B2 (ja
JP2016539083A (ja
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Priority claimed from PCT/EP2014/071028 external-priority patent/WO2015049280A1/en
Publication of JP2016539083A publication Critical patent/JP2016539083A/ja
Publication of JP2016539083A5 publication Critical patent/JP2016539083A5/ja
Application granted granted Critical
Publication of JP6527508B2 publication Critical patent/JP6527508B2/ja
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JP2016519326A 2013-10-01 2014-10-01 αVβ6を過剰発現する癌を治療及び診断する方法 Active JP6527508B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361885302P 2013-10-01 2013-10-01
US61/885,302 2013-10-01
PCT/EP2014/071028 WO2015049280A1 (en) 2013-10-01 2014-10-01 Methods of treating and diagnosing alpha-v-beta-6 overexpressing cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019052035A Division JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Publications (3)

Publication Number Publication Date
JP2016539083A JP2016539083A (ja) 2016-12-15
JP2016539083A5 true JP2016539083A5 (enExample) 2017-11-09
JP6527508B2 JP6527508B2 (ja) 2019-06-05

Family

ID=51655742

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016519326A Active JP6527508B2 (ja) 2013-10-01 2014-10-01 αVβ6を過剰発現する癌を治療及び診断する方法
JP2019052035A Pending JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Family Applications After (1)

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JP2019052035A Pending JP2019142876A (ja) 2013-10-01 2019-03-20 αVβ6を過剰発現する癌を治療及び診断する方法

Country Status (7)

Country Link
US (2) US20160319032A1 (enExample)
EP (1) EP3052523B1 (enExample)
JP (2) JP6527508B2 (enExample)
CN (1) CN106232625B (enExample)
AU (1) AU2014331118B2 (enExample)
CA (1) CA2925057A1 (enExample)
WO (1) WO2015049280A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015109391A1 (en) 2014-01-24 2015-07-30 Children's Hospital Of Eastern Ontario Research Institute Inc. Smc combination therapy for the treatment of cancer
CN108367049A (zh) * 2015-12-11 2018-08-03 海德堡吕布莱希特-卡尔斯大学 Pkm2调节剂和hmgb1的组合制剂
MX383920B (es) 2016-05-26 2025-03-14 Recurium Ip Holdings Llc Compuestos inhibidores de egfr.
IL315266A (en) * 2016-06-14 2024-10-01 Merck Sharp ַ& Dohme Llc Anti-coagulation factor xi antibodies
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
CN106950371B (zh) * 2017-02-17 2019-03-08 张灏 Pd-l1、cdk5和ctla4中的至少一种在制备肿瘤诊断试剂盒中的用途
MX2019011717A (es) * 2017-03-31 2019-12-16 Univ California Composiciones y metodos para focalizar y matar celulas madre positivas a cancer alfa-v beta-3 y tratar cancer resistentes a farmacos.
CN109265551B (zh) * 2018-09-25 2020-09-15 华东师范大学 Cd38抗体、嵌合抗原受体和药物
EP3873540A4 (en) 2018-10-31 2022-07-27 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
WO2020092839A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
AU2020224164A1 (en) * 2019-02-22 2022-02-10 Candel Therapeutics, Inc. GMCI and DDRI combination therapy for treating cancer
US11827709B2 (en) 2019-12-05 2023-11-28 Seagen Inc. Anti-AVB6 antibodies and antibody-drug conjugates
US11579085B2 (en) * 2020-07-17 2023-02-14 Robert Bosch Gmbh Sensing devices
CN114195893A (zh) * 2020-09-17 2022-03-18 百奥泰生物制药股份有限公司 抗整联蛋白抗体或抗原结合片段及其应用
CN118440187A (zh) * 2023-01-05 2024-08-06 郴州市第一人民医院 一种抗SARS-like冠状病毒和/或新冠突变株的广谱抗体及其应用
CN117603348B (zh) * 2023-11-24 2024-08-09 优睿赛思(武汉)生物科技有限公司 抗新型冠状病毒s蛋白的全人源化抗体及其应用
WO2025163120A1 (en) 2024-02-01 2025-08-07 Adcytherix Sas ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-INTEGRIN ΑVβ6 BINDING ANTIBODY
EP4595981A1 (en) * 2024-02-01 2025-08-06 Jack Elands Antibody-drug conjugates comprising an anti-integrin v 6 binding antibody

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535425A (en) * 2002-03-13 2008-05-30 Biogen Idec Inc Anti-alphavbeta6 antibodies
CN104072614B (zh) * 2005-07-08 2017-04-26 生物基因Ma公司 抗-αvβ6 抗体及其用途
EP2064244B1 (en) * 2006-08-03 2019-06-05 MedImmune Limited ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF
SG11201404354UA (en) * 2012-02-17 2014-10-30 Seattle Genetics Inc ANTIBODIES TO INTEGRIN αVβ6 AND USE OF SAME TO TREAT CANCER

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