JP2016539083A5 - - Google Patents
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- Publication number
- JP2016539083A5 JP2016539083A5 JP2016519326A JP2016519326A JP2016539083A5 JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5 JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5
- Authority
- JP
- Japan
- Prior art keywords
- αvβ6
- her2
- inhibitor
- binding agent
- targeted binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361885302P | 2013-10-01 | 2013-10-01 | |
| US61/885,302 | 2013-10-01 | ||
| PCT/EP2014/071028 WO2015049280A1 (en) | 2013-10-01 | 2014-10-01 | Methods of treating and diagnosing alpha-v-beta-6 overexpressing cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019052035A Division JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539083A JP2016539083A (ja) | 2016-12-15 |
| JP2016539083A5 true JP2016539083A5 (enExample) | 2017-11-09 |
| JP6527508B2 JP6527508B2 (ja) | 2019-06-05 |
Family
ID=51655742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016519326A Active JP6527508B2 (ja) | 2013-10-01 | 2014-10-01 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
| JP2019052035A Pending JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019052035A Pending JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20160319032A1 (enExample) |
| EP (1) | EP3052523B1 (enExample) |
| JP (2) | JP6527508B2 (enExample) |
| CN (1) | CN106232625B (enExample) |
| AU (1) | AU2014331118B2 (enExample) |
| CA (1) | CA2925057A1 (enExample) |
| WO (1) | WO2015049280A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10441654B2 (en) | 2014-01-24 | 2019-10-15 | Children's Hospital Of Eastern Ontario Research Institute Inc. | SMC combination therapy for the treatment of cancer |
| CN108367049A (zh) * | 2015-12-11 | 2018-08-03 | 海德堡吕布莱希特-卡尔斯大学 | Pkm2调节剂和hmgb1的组合制剂 |
| CN109311858B (zh) | 2016-05-26 | 2021-12-03 | 里科瑞尔姆Ip控股有限责任公司 | Egfr抑制剂化合物 |
| CN116425879A (zh) * | 2016-06-14 | 2023-07-14 | 默沙东有限责任公司 | 抗-凝血因子xi抗体 |
| MX393780B (es) | 2017-01-17 | 2025-03-24 | Heparegenix Gmbh | Inhibidores de proteina cinasa para promover la regeneracion hepatica o reducir o prevenir la muerte de hepatocitos |
| CN106950371B (zh) * | 2017-02-17 | 2019-03-08 | 张灏 | Pd-l1、cdk5和ctla4中的至少一种在制备肿瘤诊断试剂盒中的用途 |
| EP3600422B1 (en) * | 2017-03-31 | 2023-10-18 | The Regents of the University of California | Compositions for use in methods for targeting and killing alpha-v beta-3-positive cancer stem cells (cscs) and treating drug resistant cancers |
| CN109265551B (zh) * | 2018-09-25 | 2020-09-15 | 华东师范大学 | Cd38抗体、嵌合抗原受体和药物 |
| US12257286B2 (en) | 2018-10-31 | 2025-03-25 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| WO2020092839A1 (en) | 2018-10-31 | 2020-05-07 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| AU2020224164A1 (en) * | 2019-02-22 | 2022-02-10 | Candel Therapeutics, Inc. | GMCI and DDRI combination therapy for treating cancer |
| TWI884192B (zh) | 2019-12-05 | 2025-05-21 | 美商西健公司 | 抗αＶβ６抗體及抗體-藥物結合物 |
| US11579085B2 (en) * | 2020-07-17 | 2023-02-14 | Robert Bosch Gmbh | Sensing devices |
| CN114195893A (zh) * | 2020-09-17 | 2022-03-18 | 百奥泰生物制药股份有限公司 | 抗整联蛋白抗体或抗原结合片段及其应用 |
| CN117603348B (zh) * | 2023-11-24 | 2024-08-09 | 优睿赛思(武汉)生物科技有限公司 | 抗新型冠状病毒s蛋白的全人源化抗体及其应用 |
| EP4595981A1 (en) * | 2024-02-01 | 2025-08-06 | Jack Elands | Antibody-drug conjugates comprising an anti-integrin v 6 binding antibody |
| WO2025163120A1 (en) | 2024-02-01 | 2025-08-07 | Adcytherix Sas | ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-INTEGRIN ΑVβ6 BINDING ANTIBODY |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04008870A (es) * | 2002-03-13 | 2005-06-17 | Biogen Idec Inc | Anticuerpos anti-avb6. |
| CN102875681A (zh) * | 2005-07-08 | 2013-01-16 | 拜奥根Idec马萨诸塞公司 | 抗-αvβ6抗体及其用途 |
| EP2064244B1 (en) * | 2006-08-03 | 2019-06-05 | MedImmune Limited | ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF |
| KR102084806B1 (ko) * | 2012-02-17 | 2020-03-04 | 시애틀 지네틱스, 인크. | 인테그린 αvβ6에 대한 항체 및 암을 치료하기 위한 그의 용도 |
-
2014
- 2014-10-01 EP EP14777632.2A patent/EP3052523B1/en not_active Not-in-force
- 2014-10-01 US US15/026,350 patent/US20160319032A1/en not_active Abandoned
- 2014-10-01 CA CA2925057A patent/CA2925057A1/en not_active Abandoned
- 2014-10-01 CN CN201480065738.4A patent/CN106232625B/zh active Active
- 2014-10-01 AU AU2014331118A patent/AU2014331118B2/en active Active
- 2014-10-01 JP JP2016519326A patent/JP6527508B2/ja active Active
- 2014-10-01 WO PCT/EP2014/071028 patent/WO2015049280A1/en not_active Ceased
-
2018
- 2018-11-06 US US16/181,907 patent/US20190389967A1/en not_active Abandoned
-
2019
- 2019-03-20 JP JP2019052035A patent/JP2019142876A/ja active Pending
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