JP2016538337A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016538337A5 JP2016538337A5 JP2016552698A JP2016552698A JP2016538337A5 JP 2016538337 A5 JP2016538337 A5 JP 2016538337A5 JP 2016552698 A JP2016552698 A JP 2016552698A JP 2016552698 A JP2016552698 A JP 2016552698A JP 2016538337 A5 JP2016538337 A5 JP 2016538337A5
- Authority
- JP
- Japan
- Prior art keywords
- iii
- group
- tetraazabicyclo
- methyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*c1cc(CN(CC2)CC(CC*)CN3*(C)CCN2CC(C)CNCC3)nc(C(O*)=O)c1 Chemical compound C*c1cc(CN(CC2)CC(CC*)CN3*(C)CCN2CC(C)CNCC3)nc(C(O*)=O)c1 0.000 description 16
- YQLVIOYSGHEJDA-UHFFFAOYSA-N CC(CCC(O1)=O)C1=O Chemical compound CC(CCC(O1)=O)C1=O YQLVIOYSGHEJDA-UHFFFAOYSA-N 0.000 description 2
- AASBXERNXVFUEJ-UHFFFAOYSA-N CCC(ON(C(CC1)=O)C1=O)=O Chemical compound CCC(ON(C(CC1)=O)C1=O)=O AASBXERNXVFUEJ-UHFFFAOYSA-N 0.000 description 2
- IKFUKZKAVAQSTB-UHFFFAOYSA-N OC(c1cccc(CN(CCC2)CCN3CCN2CCNCCC3)n1)=O Chemical compound OC(c1cccc(CN(CCC2)CCN3CCN2CCNCCC3)n1)=O IKFUKZKAVAQSTB-UHFFFAOYSA-N 0.000 description 2
- UEGPGVUSFAKKDP-UHFFFAOYSA-N CC(CNCC1)CN2CCN(Cc3nc(C(O)=O)ccc3)CCCN1C(C)CC2 Chemical compound CC(CNCC1)CN2CCN(Cc3nc(C(O)=O)ccc3)CCCN1C(C)CC2 UEGPGVUSFAKKDP-UHFFFAOYSA-N 0.000 description 1
- GWTIHISAXXJCET-UHFFFAOYSA-N OC(c1cccc(CN(CCC2)CCN(CCC3)CCN2CCN3[IH]I)n1)=O Chemical compound OC(c1cccc(CN(CCC2)CCN(CCC3)CCN2CCN3[IH]I)n1)=O GWTIHISAXXJCET-UHFFFAOYSA-N 0.000 description 1
- CHCSUFBDJNCZRY-UHFFFAOYSA-N OC(c1cccc(CN(CCCN(CCC2)CC3)CCN2CCCN3I)n1)=O Chemical compound OC(c1cccc(CN(CCCN(CCC2)CC3)CCN2CCCN3I)n1)=O CHCSUFBDJNCZRY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13192597.6A EP2871186B1 (en) | 2013-11-12 | 2013-11-12 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof |
| EP13192597.6 | 2013-11-12 | ||
| PCT/EP2014/074415 WO2015071334A1 (en) | 2013-11-12 | 2014-11-12 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016538337A JP2016538337A (ja) | 2016-12-08 |
| JP2016538337A5 true JP2016538337A5 (https=) | 2017-12-14 |
| JP6514712B2 JP6514712B2 (ja) | 2019-05-15 |
Family
ID=49582592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552698A Active JP6514712B2 (ja) | 2013-11-12 | 2014-11-12 | ピコリン酸架橋シクラム、金属カチオンとのキレートおよびそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10434199B2 (https=) |
| EP (2) | EP2871186B1 (https=) |
| JP (1) | JP6514712B2 (https=) |
| CA (1) | CA2930274C (https=) |
| ES (1) | ES2657704T3 (https=) |
| WO (1) | WO2015071334A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3774803A1 (en) | 2018-03-30 | 2021-02-17 | Centre national de la recherche scientifique | Pyclen-based macrocyclic ligands, chelates thereof and uses thereof |
| WO2025153023A1 (en) * | 2024-01-17 | 2025-07-24 | C Ray Therapeutics (Shanghai) Co., Ltd. | Fibroblast activation protein ligands and the use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| KR101199570B1 (ko) * | 2009-09-09 | 2012-11-13 | 경북대학교 산학협력단 | 신규한 테트라아자 거대고리 화합물, 제조방법 및 그 용도 |
| WO2012037648A1 (en) * | 2010-09-20 | 2012-03-29 | Nordion (Canada) Inc. | Process for chelating copper ions using cb-te2a bifunctional chelate |
| FR2982611B1 (fr) | 2011-11-16 | 2014-01-03 | Univ Bretagne Occidentale | Procedes de preparation de composes tetraazacycloalcanes fonctionnels a l'aide d'un compose cyclique bisaminal particulier. |
-
2013
- 2013-11-12 EP EP13192597.6A patent/EP2871186B1/en active Active
-
2014
- 2014-11-12 ES ES14799724.1T patent/ES2657704T3/es active Active
- 2014-11-12 JP JP2016552698A patent/JP6514712B2/ja active Active
- 2014-11-12 WO PCT/EP2014/074415 patent/WO2015071334A1/en not_active Ceased
- 2014-11-12 CA CA2930274A patent/CA2930274C/en active Active
- 2014-11-12 US US15/036,133 patent/US10434199B2/en active Active
- 2014-11-12 EP EP14799724.1A patent/EP3068787B1/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021523225A5 (https=) | ||
| US9981967B2 (en) | Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof | |
| JP2683080B2 (ja) | トリ‐アザ大環状化合物及びそれらの金属錯体 | |
| JP2021532162A5 (https=) | ||
| JP2016153410A5 (https=) | ||
| JP2006507265A5 (https=) | ||
| JP2019513734A5 (https=) | ||
| US20240343706A1 (en) | Piperidine-2,6-dione derivatives which bind to cereblon, and methods of use thereof | |
| RU2218337C2 (ru) | Производные тиазола, способ их получения и фармацевтическая композиция на их основе | |
| ES2475721T3 (es) | Síntesis de un piperazina neuroestimulante | |
| JP2018532788A5 (https=) | ||
| JP2017521436A5 (https=) | ||
| JP2021501756A5 (https=) | ||
| US20090148382A1 (en) | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | |
| JP2023554079A (ja) | リガンド及びそれらの使用 | |
| JP2016538337A5 (https=) | ||
| JPWO2019213445A5 (https=) | ||
| JPH07506667A (ja) | 錯化剤並びに治療及び診断用組成物及び方法に有用な標的化免疫試薬 | |
| US20150291538A1 (en) | Macrocyclic Compositions And Metal Complexes For Bioimaging And Biomedical Applications | |
| AU2023387509A1 (en) | An anti-tumor compound and use thereof | |
| JP2014500268A5 (https=) | ||
| TWI833796B (zh) | 磷酸肌醇3激酶(pi3k)抑制劑之結晶形式 | |
| JP2018501266A5 (https=) | ||
| AU2015203742A1 (en) | Labeled inhibitors of prostate specific membrane antigen (psma), biological evaluation, and use as imaging agents | |
| KR101142153B1 (ko) | 개선된 플루오르-18 표지를 위한 트리아자노난 유도체 또는 이의 약학적으로 허용가능한 염 |