JP2016535983A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016535983A5 JP2016535983A5 JP2016521773A JP2016521773A JP2016535983A5 JP 2016535983 A5 JP2016535983 A5 JP 2016535983A5 JP 2016521773 A JP2016521773 A JP 2016521773A JP 2016521773 A JP2016521773 A JP 2016521773A JP 2016535983 A5 JP2016535983 A5 JP 2016535983A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- polymerase
- nucleotide
- binding site
- chemical modification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361887614P | 2013-10-07 | 2013-10-07 | |
| US61/887,614 | 2013-10-07 | ||
| PCT/US2014/059489 WO2015054247A1 (en) | 2013-10-07 | 2014-10-07 | Detection of chemical modifications in nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016535983A JP2016535983A (ja) | 2016-11-24 |
| JP2016535983A5 true JP2016535983A5 (enExample) | 2017-11-02 |
| JP6612220B2 JP6612220B2 (ja) | 2019-11-27 |
Family
ID=52813579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016521773A Active JP6612220B2 (ja) | 2013-10-07 | 2014-10-07 | 核酸における化学修飾の検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10240188B2 (enExample) |
| EP (1) | EP3055413B1 (enExample) |
| JP (1) | JP6612220B2 (enExample) |
| ES (1) | ES2791873T3 (enExample) |
| WO (1) | WO2015054247A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018085752A2 (en) * | 2016-11-07 | 2018-05-11 | nanoSUR LLC | Post-transcriptionally chemically modified double strand rnas |
| US12195788B2 (en) * | 2017-01-12 | 2025-01-14 | University Of Central Florida Research Foundation, Inc. | High-throughput and single nucleotide resolution techniques for the determination of RNA post-transcriptional modifications |
| RU2659025C1 (ru) * | 2017-06-14 | 2018-06-26 | Общество с ограниченной ответственностью "ЛЭНДИГРАД" | Способы кодирования и декодирования информации |
| CN109517889B (zh) * | 2017-09-18 | 2022-04-05 | 苏州吉赛基因测序科技有限公司 | 一种基于高通量测序分析寡核苷酸序列杂质的方法及应用 |
| WO2019109046A1 (en) | 2017-11-30 | 2019-06-06 | Arrakis Therapeutics, Inc. | Nucleic acid-binding photoprobes and uses thereof |
| CN114438168B (zh) * | 2020-11-05 | 2024-10-22 | 寻鲸生科(北京)智能技术有限公司 | 一种全转录组水平rna结构检测方法及其应用 |
| WO2022094863A1 (zh) * | 2020-11-05 | 2022-05-12 | 清华大学 | 一种全转录组水平rna结构检测方法及其应用 |
| CN114507721B (zh) * | 2020-11-16 | 2024-04-09 | 寻鲸生科(北京)智能技术有限公司 | 一种全转录组rna结构探测的方法及其应用 |
| EP4202056A4 (en) * | 2020-11-18 | 2024-05-29 | Xforest Therapeutics Co., Ltd. | Rna probe for mutation profiling and use thereof |
| US11795500B2 (en) | 2021-08-19 | 2023-10-24 | Eclipse Bioinnovations, Inc. | Methods for detecting RNA binding protein complexes |
| WO2023235820A1 (en) * | 2022-06-03 | 2023-12-07 | Eclipse Bioinnovations, Inc. | Methods for obtaining rna secondary structure of lnp-encapsulated rna |
| WO2025137453A1 (en) * | 2023-12-20 | 2025-06-26 | New England Biolabs, Inc. | Compositions, methods, kits, and instruments for analyzing rna structure |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE347616T1 (de) | 1999-04-30 | 2006-12-15 | Cyclops Genome Sciences Ltd | Ribonukleinsäurederivate |
| US20070196832A1 (en) | 2006-02-22 | 2007-08-23 | Efcavitch J William | Methods for mutation detection |
| WO2007145940A2 (en) | 2006-06-05 | 2007-12-21 | The University Of North Carolina At Chapel Hill | High-throughput rna structure analysis |
| EP2053131A1 (en) * | 2007-10-19 | 2009-04-29 | Ludwig-Maximilians-Universität München | Method for determining methylation at deoxycytosine residues |
| US20130288917A1 (en) * | 2010-10-21 | 2013-10-31 | The Board Of Trustees Of The Leland Stanford Junior University | Rapid High Resolution, High Throughput RNA Structure, RNA-Macromolecular Interaction, and RNA-Small Molecule Interaction Mapping |
-
2014
- 2014-10-07 EP EP14851691.7A patent/EP3055413B1/en active Active
- 2014-10-07 WO PCT/US2014/059489 patent/WO2015054247A1/en not_active Ceased
- 2014-10-07 US US15/027,813 patent/US10240188B2/en active Active
- 2014-10-07 ES ES14851691T patent/ES2791873T3/es active Active
- 2014-10-07 JP JP2016521773A patent/JP6612220B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016535983A5 (enExample) | ||
| Gołębiewski et al. | Generating amplicon reads for microbial community assessment with next‐generation sequencing | |
| Komarova et al. | Implementation of high-throughput sequencing (HTS) in aptamer selection technology | |
| El-Metwally et al. | Next generation sequencing technologies and challenges in sequence assembly | |
| Ari et al. | Next-generation sequencing: advantages, disadvantages, and future | |
| Oyola et al. | Optimizing Illumina next-generation sequencing library preparation for extremely AT-biased genomes | |
| Sheynkman et al. | ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms | |
| JP6612220B2 (ja) | 核酸における化学修飾の検出 | |
| JP6789935B2 (ja) | データの速度および密度を増大させるための多数のプライマーからのシーケンシング | |
| Nicholson et al. | Exploring the architecture of viral RNA genomes | |
| Asp | How to combine ChIP with qPCR | |
| Höper et al. | A comprehensive deep sequencing strategy for full-length genomes of influenza A | |
| Thompson et al. | Winnowing DNA for rare sequences: highly specific sequence and methylation based enrichment | |
| CN102586456A (zh) | 一种多重竞争性pcr检测拷贝数变异的方法 | |
| de Sá et al. | Next-generation sequencing and data analysis: strategies, tools, pipelines and protocols | |
| Watters et al. | Mapping RNA structure in vitro with SHAPE chemistry and next-generation sequencing (SHAPE-Seq) | |
| Zhu et al. | A rapid on-site visualization platform based on RPA coupled with CRISPR-Cas12a for the detection of genetically modified papaya ‘Huanong No. 1’ | |
| Jones | High-throughput sequencing and metagenomics | |
| Low et al. | Introduction to next generation sequencing technologies | |
| Bao et al. | Prediction of protein–DNA complex mobility in gel-free capillary electrophoresis | |
| Lazov et al. | Multiplex real-time RT-PCR assays for detection and differentiation of porcine enteric coronaviruses | |
| Schellenberg et al. | Pyrosequencing of chaperonin-60 (cpn60) amplicons as a means of determining microbial community composition | |
| Gazestani et al. | circTAIL-seq, a targeted method for deep analysis of RNA 3′ tails, reveals transcript-specific differences by multiple metrics | |
| Mee et al. | High resolution identity testing of inactivated poliovirus vaccines | |
| WO2012023675A1 (ko) | 변형 뉴클레오티드 및 이를 이용한 실시간 중합효소 반응 |