JP2016535270A - 膵臓癌に関連する物質及び方法 - Google Patents

膵臓癌に関連する物質及び方法 Download PDF

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JP2016535270A
JP2016535270A JP2016533958A JP2016533958A JP2016535270A JP 2016535270 A JP2016535270 A JP 2016535270A JP 2016533958 A JP2016533958 A JP 2016533958A JP 2016533958 A JP2016533958 A JP 2016533958A JP 2016535270 A JP2016535270 A JP 2016535270A
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tumor
protein
pancreatic
proteins
phosphorylation
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JP2016535270A5 (enExample
Inventor
ヨー ゼン
ヨー ゼン
ヒートン ニゲル
ヒートン ニゲル
クアグリア アルベルト
クアグリア アルベルト
ブリットン デビッド
ブリットン デビッド
ワード マルコルム
ワード マルコルム
ピケ イアン
ピケ イアン
ミトラ ビクラム
ミトラ ビクラム
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Proteome Sciences PLC
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Electrophoretics Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/14—Post-translational modifications [PTMs] in chemical analysis of biological material phosphorylation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016533958A 2013-08-13 2014-08-13 膵臓癌に関連する物質及び方法 Pending JP2016535270A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1314485.2 2013-08-13
GBGB1314485.2A GB201314485D0 (en) 2013-08-13 2013-08-13 Materials and methods relating to pancreatic cancer
PCT/GB2014/052475 WO2015022530A2 (en) 2013-08-13 2014-08-13 Materials and methods relating to pancreatic cancer

Publications (2)

Publication Number Publication Date
JP2016535270A true JP2016535270A (ja) 2016-11-10
JP2016535270A5 JP2016535270A5 (enExample) 2017-12-28

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US (1) US20160195536A1 (enExample)
EP (1) EP3033624A2 (enExample)
JP (1) JP2016535270A (enExample)
CN (1) CN105637367A (enExample)
CA (1) CA2920946A1 (enExample)
GB (1) GB201314485D0 (enExample)
WO (1) WO2015022530A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020514684A (ja) * 2016-12-20 2020-05-21 トリート４ライフ アーベー 質量分析によってｂｒａｆ突然変異および野生型ｂｒａｆタンパク質を定める方法
WO2022154037A1 (ja) * 2021-01-14 2022-07-21 公立大学法人福島県立医科大学 がんの予後バイオマーカー

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017044715A1 (en) * 2015-09-09 2017-03-16 Somalogic, Inc. Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles
US10617720B2 (en) * 2016-10-20 2020-04-14 Miltenyi Biotech, GmbH Chimeric antigen receptor specific for tumor cells
EP3811081A1 (en) * 2018-06-21 2021-04-28 Universiteit Utrecht Holding B.V. Method for monitoring kinase activity in a sample
CN111066727B (zh) * 2019-12-20 2021-08-27 中国人民解放军陆军军医大学 在低氧性血睾屏障通透中作用机制的小鼠模型构建方法
IT202000016807A1 (it) * 2020-07-10 2022-01-10 Humanitas Mirasole Spa Peptidi associati a tumore e loro impiego

Citations (7)

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Publication number Priority date Publication date Assignee Title
WO2004055519A2 (en) * 2002-12-17 2004-07-01 Sinogenomax Co. Ltd. Specific markers for pancreatic cancer
US20110294136A1 (en) * 2006-12-01 2011-12-01 Helmut Meyer Biomarker for diagnosing pancreatic cancer
US20120009194A1 (en) * 2010-06-16 2012-01-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Antibodies to endoplasmin and their use
JP2012516445A (ja) * 2009-01-27 2012-07-19 ホロジック，インコーポレイテッド 体液における新生児敗血症の検出のためのバイオマーカー
US20120309706A1 (en) * 2010-02-01 2012-12-06 Ab Science Combined treatment of pancreatic cancer with gemcitabine and masitinib
JP2013525786A (ja) * 2010-04-19 2013-06-20 バイオマーカー ストラテジーズ リミテッド ライアビリティ カンパニー 薬物感受性、薬物抵抗性および疾患進行の予測のための組成物および方法
JP2013527464A (ja) * 2010-06-01 2013-06-27 メタノミクス ヘルス ゲーエムベーハー 対象において膵臓がんを診断する手段及び方法

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US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
KR970002255B1 (ko) 1990-06-11 1997-02-26 넥스스타 파아마슈티컬드, 인크. 핵산 리간드
DE60239962D1 (de) 2001-08-14 2011-06-16 Harvard College Absolute quantifizierung von proteinen und modifizierten formen davon mittels mehrstufiger massenspektrometrie
CN1726395A (zh) * 2002-12-17 2006-01-25 北京诺赛基因组研究中心有限公司 胰腺癌的特异标记
US8346482B2 (en) * 2003-08-22 2013-01-01 Fernandez Dennis S Integrated biosensor and simulation system for diagnosis and therapy
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
CA2726531A1 (en) * 2008-06-05 2009-12-10 University Health Network Compositions and methods for classifying lung cancer and prognosing lung cancer survival
WO2011088030A1 (en) * 2010-01-15 2011-07-21 Bryan William Jones Disease diagnosis and treatment using computational molecular phenotyping
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Publication number Priority date Publication date Assignee Title
WO2004055519A2 (en) * 2002-12-17 2004-07-01 Sinogenomax Co. Ltd. Specific markers for pancreatic cancer
US20110294136A1 (en) * 2006-12-01 2011-12-01 Helmut Meyer Biomarker for diagnosing pancreatic cancer
JP2012516445A (ja) * 2009-01-27 2012-07-19 ホロジック，インコーポレイテッド 体液における新生児敗血症の検出のためのバイオマーカー
US20120309706A1 (en) * 2010-02-01 2012-12-06 Ab Science Combined treatment of pancreatic cancer with gemcitabine and masitinib
JP2013525786A (ja) * 2010-04-19 2013-06-20 バイオマーカー ストラテジーズ リミテッド ライアビリティ カンパニー 薬物感受性、薬物抵抗性および疾患進行の予測のための組成物および方法
JP2013527464A (ja) * 2010-06-01 2013-06-27 メタノミクス ヘルス ゲーエムベーハー 対象において膵臓がんを診断する手段及び方法
US20120009194A1 (en) * 2010-06-16 2012-01-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Antibodies to endoplasmin and their use

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PARK, B.W. ET AL.: "Homeodomain-interacting Protein Kinase 1 (HIPK1) Expression in Breast Cancer Tissues", JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol. 42, no. 12, JPN6018017010, 15 October 2012 (2012-10-15), pages 1138 - 1145, ISSN: 0003795207 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020514684A (ja) * 2016-12-20 2020-05-21 トリート４ライフ アーベー 質量分析によってｂｒａｆ突然変異および野生型ｂｒａｆタンパク質を定める方法
WO2022154037A1 (ja) * 2021-01-14 2022-07-21 公立大学法人福島県立医科大学 がんの予後バイオマーカー

Also Published As

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CN105637367A (zh) 2016-06-01
EP3033624A2 (en) 2016-06-22
WO2015022530A3 (en) 2015-04-09
WO2015022530A2 (en) 2015-02-19
CA2920946A1 (en) 2015-02-19
GB201314485D0 (en) 2013-09-25
US20160195536A1 (en) 2016-07-07

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