JP2016531949A5 - - Google Patents
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- Publication number
- JP2016531949A5 JP2016531949A5 JP2016546191A JP2016546191A JP2016531949A5 JP 2016531949 A5 JP2016531949 A5 JP 2016531949A5 JP 2016546191 A JP2016546191 A JP 2016546191A JP 2016546191 A JP2016546191 A JP 2016546191A JP 2016531949 A5 JP2016531949 A5 JP 2016531949A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- composition
- olopatadine
- mometasone
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 16
- JBIMVDZLSHOPLA-LSCVHKIXSA-N olopatadine Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 JBIMVDZLSHOPLA-LSCVHKIXSA-N 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 10
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 claims 9
- 229960004114 olopatadine Drugs 0.000 claims 9
- 201000010105 allergic rhinitis Diseases 0.000 claims 8
- 239000007921 spray Substances 0.000 claims 8
- 229960001664 mometasone Drugs 0.000 claims 7
- 206010039085 Rhinitis allergic Diseases 0.000 claims 6
- 239000012458 free base Substances 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims 2
- HVRLZEKDTUEKQH-NOILCQHBSA-N Olopatadine hydrochloride Chemical group Cl.C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 HVRLZEKDTUEKQH-NOILCQHBSA-N 0.000 claims 2
- 208000036284 Rhinitis seasonal Diseases 0.000 claims 2
- 239000013566 allergen Substances 0.000 claims 2
- 208000027993 eye symptom Diseases 0.000 claims 2
- 229960002744 mometasone furoate Drugs 0.000 claims 2
- WOFMFGQZHJDGCX-ZULDAHANSA-N mometasone furoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(Cl)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)C(=O)CCl)C(=O)C1=CC=CO1 WOFMFGQZHJDGCX-ZULDAHANSA-N 0.000 claims 2
- 229960003139 olopatadine hydrochloride Drugs 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000017022 seasonal allergic rhinitis Diseases 0.000 claims 2
- 238000010181 skin prick test Methods 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3174MU2013 | 2013-10-04 | ||
| IN3174MUM2013 | 2013-10-04 | ||
| PCT/IB2014/065035 WO2015049665A1 (en) | 2013-10-04 | 2014-10-03 | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018076047A Division JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531949A JP2016531949A (ja) | 2016-10-13 |
| JP2016531949A5 true JP2016531949A5 (enExample) | 2016-11-24 |
| JP6419195B2 JP6419195B2 (ja) | 2018-11-07 |
Family
ID=51982657
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016546191A Active JP6419195B2 (ja) | 2013-10-04 | 2014-10-03 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2018076047A Active JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2020028523A Pending JP2020097624A (ja) | 2013-10-04 | 2020-02-21 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018076047A Active JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2020028523A Pending JP2020097624A (ja) | 2013-10-04 | 2020-02-21 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10646500B2 (enExample) |
| EP (2) | EP4272839A3 (enExample) |
| JP (3) | JP6419195B2 (enExample) |
| CN (2) | CN105792828A (enExample) |
| HK (1) | HK1215674A1 (enExample) |
| MX (2) | MX2015009429A (enExample) |
| MY (1) | MY176808A (enExample) |
| PH (1) | PH12015502302A1 (enExample) |
| RU (1) | RU2686670C2 (enExample) |
| UA (1) | UA120587C2 (enExample) |
| WO (1) | WO2015049665A1 (enExample) |
| ZA (1) | ZA201504740B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| US9937189B2 (en) | 2013-09-13 | 2018-04-10 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| US10016443B2 (en) | 2013-10-04 | 2018-07-10 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10653661B2 (en) | 2013-10-04 | 2020-05-19 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| UA120587C2 (uk) * | 2013-10-04 | 2020-01-10 | Гленмарк Спешіалті С.А. | Спосіб лікування алергічного риніту з використанням комбінації мометазону та олопатадину |
| US10548907B2 (en) | 2013-10-04 | 2020-02-04 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US11679210B2 (en) | 2014-10-03 | 2023-06-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| JP2020526233A (ja) * | 2017-06-28 | 2020-08-31 | グレンマーク・スペシャルティー・エスエー | 鼻炎の治療のための投与装置及び医薬組成物 |
| EP3755375B1 (en) * | 2018-02-23 | 2025-03-05 | Glenmark Specialty S.A. | Treatment of allergic rhinitis in pediatric subjects using a combination of mometasone and olopatadine |
| US12303635B2 (en) | 2018-04-16 | 2025-05-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US6127353A (en) | 1991-09-06 | 2000-10-03 | Schering Corporation | Mometasone furoate monohydrate, process for making same and pharmaceutical compositions |
| PE44995A1 (es) | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
| US5837699A (en) * | 1994-01-27 | 1998-11-17 | Schering Corporation | Use of mometasone furoate for treating upper airway passage diseases |
| EP1227812B1 (en) | 1999-10-08 | 2007-04-18 | Schering Corporation | Topical nasal treatment using desloratadine and mometasone furoate |
| US7977376B2 (en) | 2001-06-27 | 2011-07-12 | Novartis Ag | Olopatadine formulations for topical nasal administration |
| MXPA05005044A (es) * | 2002-11-12 | 2005-07-01 | Alcon Inc | El uso de un agente antialergico y un esteroide para tratar rinitis alergica. |
| US8912174B2 (en) | 2003-04-16 | 2014-12-16 | Mylan Pharmaceuticals Inc. | Formulations and methods for treating rhinosinusitis |
| EP1814538B1 (en) | 2004-11-24 | 2009-09-23 | Alcon, Inc. | Method of delivering nasal spray |
| CN101257891A (zh) * | 2005-09-01 | 2008-09-03 | 比奥里波克斯公司 | 包含抗组胺剂以及皮质类固醇的脂质体组合物及其在制备治疗鼻炎以及相关疾病的药物中的用途 |
| CA2631757A1 (en) | 2005-12-02 | 2007-06-07 | Elan Pharma International Limited | Novel mometasone compositions and methods of making and using the same |
| US8771711B2 (en) | 2006-04-21 | 2014-07-08 | Toko Yakuhin Kogyo Kabushiki Kaisha | Sprayable gel-type skin/mucosa-adhesive preparation and administration system using the preparation |
| WO2009003199A1 (en) * | 2007-06-28 | 2008-12-31 | Cydex Pharmaceuticals, Inc. | Nasal and ophthalmic delivery of aqueous corticosteroid solutions |
| WO2010009028A1 (en) * | 2008-07-15 | 2010-01-21 | Schering Corporation | Intranasal compositions comprising a decongestant and a corticosteroid |
| US8642069B2 (en) | 2008-08-27 | 2014-02-04 | Alexander D. Goldin | Composition and method for treating colds |
| CN102470099A (zh) | 2009-07-17 | 2012-05-23 | 爱尔康研究有限公司 | 儿童用奥洛他定鼻腔喷雾方案 |
| CN102078285A (zh) * | 2009-11-26 | 2011-06-01 | 天津金耀集团有限公司 | 含有皮质激素和h1受体拮抗剂的鼻用原位凝胶 |
| CN102078326A (zh) * | 2009-11-26 | 2011-06-01 | 天津金耀集团有限公司 | 含有聚维酮碘与糠酸莫米松的局部使用组合物 |
| WO2011141929A2 (en) | 2010-05-11 | 2011-11-17 | Cadila Healthcare Limited | Aqueous pharmaceutical compositions of fluticasone and olopatadine |
| EP2736491B1 (en) | 2011-01-04 | 2017-04-05 | Bausch & Lomb Incorporated | Bepotastine compositions |
| WO2014064251A1 (en) | 2012-10-25 | 2014-05-01 | Novozymes A/S | Improved method for manual dish wash |
| KR20140081925A (ko) * | 2012-12-12 | 2014-07-02 | 한미약품 주식회사 | 코르티코스테로이드, 항히스타민제 및 스테비아를 포함하는 고미 차폐된 약학 제제 |
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| RS62383B1 (sr) * | 2013-09-13 | 2021-10-29 | Glenmark Specialty Sa | Stabilna farmaceutska kompozicija sa fiksnom dozom koja sadrži mometazon i olopatadin za nazalnu primenu |
| UA120587C2 (uk) * | 2013-10-04 | 2020-01-10 | Гленмарк Спешіалті С.А. | Спосіб лікування алергічного риніту з використанням комбінації мометазону та олопатадину |
-
2014
- 2014-10-03 UA UAA201507124A patent/UA120587C2/uk unknown
- 2014-10-03 RU RU2015128496A patent/RU2686670C2/ru active
- 2014-10-03 EP EP23198254.7A patent/EP4272839A3/en active Pending
- 2014-10-03 MX MX2015009429A patent/MX2015009429A/es active IP Right Grant
- 2014-10-03 CN CN201480066538.0A patent/CN105792828A/zh active Pending
- 2014-10-03 HK HK16103630.2A patent/HK1215674A1/zh unknown
- 2014-10-03 WO PCT/IB2014/065035 patent/WO2015049665A1/en not_active Ceased
- 2014-10-03 MY MYPI2015702416A patent/MY176808A/en unknown
- 2014-10-03 US US14/506,122 patent/US10646500B2/en active Active
- 2014-10-03 CN CN202110299649.8A patent/CN112773808A/zh active Pending
- 2014-10-03 JP JP2016546191A patent/JP6419195B2/ja active Active
- 2014-10-03 EP EP14802944.0A patent/EP2922553A1/en active Pending
-
2015
- 2015-07-01 ZA ZA2015/04740A patent/ZA201504740B/en unknown
- 2015-07-22 MX MX2020003035A patent/MX2020003035A/es unknown
- 2015-10-05 PH PH12015502302A patent/PH12015502302A1/en unknown
-
2018
- 2018-04-11 JP JP2018076047A patent/JP6768733B2/ja active Active
-
2020
- 2020-02-21 JP JP2020028523A patent/JP2020097624A/ja active Pending
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