JP2016531949A5 - - Google Patents
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- Publication number
- JP2016531949A5 JP2016531949A5 JP2016546191A JP2016546191A JP2016531949A5 JP 2016531949 A5 JP2016531949 A5 JP 2016531949A5 JP 2016546191 A JP2016546191 A JP 2016546191A JP 2016546191 A JP2016546191 A JP 2016546191A JP 2016531949 A5 JP2016531949 A5 JP 2016531949A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- composition
- olopatadine
- mometasone
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 16
- JBIMVDZLSHOPLA-LSCVHKIXSA-N olopatadine Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 JBIMVDZLSHOPLA-LSCVHKIXSA-N 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 10
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 claims 9
- 229960004114 olopatadine Drugs 0.000 claims 9
- 201000010105 allergic rhinitis Diseases 0.000 claims 8
- 239000007921 spray Substances 0.000 claims 8
- 229960001664 mometasone Drugs 0.000 claims 7
- 206010039085 Rhinitis allergic Diseases 0.000 claims 6
- 239000012458 free base Substances 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims 2
- HVRLZEKDTUEKQH-NOILCQHBSA-N Olopatadine hydrochloride Chemical group Cl.C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 HVRLZEKDTUEKQH-NOILCQHBSA-N 0.000 claims 2
- 208000036284 Rhinitis seasonal Diseases 0.000 claims 2
- 239000013566 allergen Substances 0.000 claims 2
- 208000027993 eye symptom Diseases 0.000 claims 2
- 229960002744 mometasone furoate Drugs 0.000 claims 2
- WOFMFGQZHJDGCX-ZULDAHANSA-N mometasone furoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(Cl)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)C(=O)CCl)C(=O)C1=CC=CO1 WOFMFGQZHJDGCX-ZULDAHANSA-N 0.000 claims 2
- 229960003139 olopatadine hydrochloride Drugs 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000017022 seasonal allergic rhinitis Diseases 0.000 claims 2
- 238000010181 skin prick test Methods 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3174MUM2013 | 2013-10-04 | ||
| IN3174MU2013 | 2013-10-04 | ||
| PCT/IB2014/065035 WO2015049665A1 (en) | 2013-10-04 | 2014-10-03 | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018076047A Division JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531949A JP2016531949A (ja) | 2016-10-13 |
| JP2016531949A5 true JP2016531949A5 (enExample) | 2016-11-24 |
| JP6419195B2 JP6419195B2 (ja) | 2018-11-07 |
Family
ID=51982657
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016546191A Active JP6419195B2 (ja) | 2013-10-04 | 2014-10-03 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2018076047A Active JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2020028523A Pending JP2020097624A (ja) | 2013-10-04 | 2020-02-21 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018076047A Active JP6768733B2 (ja) | 2013-10-04 | 2018-04-11 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
| JP2020028523A Pending JP2020097624A (ja) | 2013-10-04 | 2020-02-21 | モメタゾンおよびオロパタジンの組み合わせを使用するアレルギー性鼻炎の治療 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10646500B2 (enExample) |
| EP (2) | EP2922553A1 (enExample) |
| JP (3) | JP6419195B2 (enExample) |
| CN (2) | CN112773808A (enExample) |
| HK (1) | HK1215674A1 (enExample) |
| MX (2) | MX2015009429A (enExample) |
| MY (1) | MY176808A (enExample) |
| PH (1) | PH12015502302B1 (enExample) |
| RU (1) | RU2686670C2 (enExample) |
| UA (1) | UA120587C2 (enExample) |
| WO (1) | WO2015049665A1 (enExample) |
| ZA (1) | ZA201504740B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| US9937189B2 (en) | 2013-09-13 | 2018-04-10 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| EP2922553A1 (en) * | 2013-10-04 | 2015-09-30 | Glenmark Pharmaceuticals Limited | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10653661B2 (en) | 2013-10-04 | 2020-05-19 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10548907B2 (en) | 2013-10-04 | 2020-02-04 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10016443B2 (en) | 2013-10-04 | 2018-07-10 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US11679210B2 (en) | 2014-10-03 | 2023-06-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| DK3468532T3 (da) * | 2017-06-28 | 2021-01-04 | Glenmark Specialty Sa | Dispenseranordning og farmaceutisk sammensætning til behandling af rhinitis |
| AU2019224850B2 (en) * | 2018-02-23 | 2024-11-28 | Glenmark Specialty S.A. | Treatment of allergic rhinitis in pediatric subjects using a combination of mometasone and olopatadine |
| US12303635B2 (en) | 2018-04-16 | 2025-05-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US6127353A (en) | 1991-09-06 | 2000-10-03 | Schering Corporation | Mometasone furoate monohydrate, process for making same and pharmaceutical compositions |
| PE44995A1 (es) | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
| US5837699A (en) * | 1994-01-27 | 1998-11-17 | Schering Corporation | Use of mometasone furoate for treating upper airway passage diseases |
| EP1227812B1 (en) | 1999-10-08 | 2007-04-18 | Schering Corporation | Topical nasal treatment using desloratadine and mometasone furoate |
| US7977376B2 (en) | 2001-06-27 | 2011-07-12 | Novartis Ag | Olopatadine formulations for topical nasal administration |
| JP2006508138A (ja) * | 2002-11-12 | 2006-03-09 | アルコン，インコーポレイテッド | アレルギー性鼻炎を処置するための抗アレルギー剤およびステロイドの使用 |
| US8912174B2 (en) | 2003-04-16 | 2014-12-16 | Mylan Pharmaceuticals Inc. | Formulations and methods for treating rhinosinusitis |
| DK1814538T3 (da) | 2004-11-24 | 2009-11-02 | Alcon Inc | Fremgangsmåde til administration af næsespray |
| EP1919450B1 (en) | 2005-09-01 | 2014-06-11 | Meda AB | Antihistamine- and corticosteroid-containing liposome composition and its use for the manufacture of a medicament for treating rhinitis and related disorders |
| WO2007064912A2 (en) | 2005-12-02 | 2007-06-07 | Elan Pharma International Limited | Mometasone compositions and methods of making and using the same |
| HUE036777T2 (hu) | 2006-04-21 | 2018-07-30 | Toko Yakuhin Kogyo Kk | Bõrhöz/nyálkahártyához tapadó porlasztható gél típusú preparátum és adagolási rendszer a preparátum alkalmazásával |
| CN101795565A (zh) * | 2007-06-28 | 2010-08-04 | 锡德克斯药物公司 | 皮质类固醇水溶液的鼻部和眼部给药 |
| JP2011528355A (ja) | 2008-07-15 | 2011-11-17 | シェーリング コーポレイション | 充血除去剤およびコルチコステロイドを含む鼻腔内粗製物 |
| US8642069B2 (en) | 2008-08-27 | 2014-02-04 | Alexander D. Goldin | Composition and method for treating colds |
| WO2011008923A2 (en) | 2009-07-17 | 2011-01-20 | Alcon Research, Ltd. | Olopatadine nasal spray regimen for children |
| CN102078285A (zh) * | 2009-11-26 | 2011-06-01 | 天津金耀集团有限公司 | 含有皮质激素和h1受体拮抗剂的鼻用原位凝胶 |
| CN102078326A (zh) * | 2009-11-26 | 2011-06-01 | 天津金耀集团有限公司 | 含有聚维酮碘与糠酸莫米松的局部使用组合物 |
| WO2011141929A2 (en) | 2010-05-11 | 2011-11-17 | Cadila Healthcare Limited | Aqueous pharmaceutical compositions of fluticasone and olopatadine |
| CN103269687B (zh) | 2011-01-04 | 2016-09-14 | 伊斯塔制药公司 | 贝托斯汀组合物 |
| MX2015005081A (es) | 2012-10-25 | 2015-07-17 | Novozymes As | Metodo mejorado para el lavado manual de la vajilla. |
| KR20140081925A (ko) | 2012-12-12 | 2014-07-02 | 한미약품 주식회사 | 코르티코스테로이드, 항히스타민제 및 스테비아를 포함하는 고미 차폐된 약학 제제 |
| SMT202100563T1 (it) * | 2013-09-13 | 2021-11-12 | Glenmark Specialty Sa | Composizione farmaceutica stabile a dose fissa comprendente mometasone e olopatadina per la somministrazione nasale |
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| EP2922553A1 (en) * | 2013-10-04 | 2015-09-30 | Glenmark Pharmaceuticals Limited | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
-
2014
- 2014-10-03 EP EP14802944.0A patent/EP2922553A1/en active Pending
- 2014-10-03 HK HK16103630.2A patent/HK1215674A1/zh unknown
- 2014-10-03 CN CN202110299649.8A patent/CN112773808A/zh active Pending
- 2014-10-03 MX MX2015009429A patent/MX2015009429A/es active IP Right Grant
- 2014-10-03 EP EP23198254.7A patent/EP4272839A3/en active Pending
- 2014-10-03 MY MYPI2015702416A patent/MY176808A/en unknown
- 2014-10-03 RU RU2015128496A patent/RU2686670C2/ru active
- 2014-10-03 CN CN201480066538.0A patent/CN105792828A/zh active Pending
- 2014-10-03 US US14/506,122 patent/US10646500B2/en active Active
- 2014-10-03 UA UAA201507124A patent/UA120587C2/uk unknown
- 2014-10-03 WO PCT/IB2014/065035 patent/WO2015049665A1/en not_active Ceased
- 2014-10-03 JP JP2016546191A patent/JP6419195B2/ja active Active
-
2015
- 2015-07-01 ZA ZA2015/04740A patent/ZA201504740B/en unknown
- 2015-07-22 MX MX2020003035A patent/MX2020003035A/es unknown
- 2015-10-05 PH PH12015502302A patent/PH12015502302B1/en unknown
-
2018
- 2018-04-11 JP JP2018076047A patent/JP6768733B2/ja active Active
-
2020
- 2020-02-21 JP JP2020028523A patent/JP2020097624A/ja active Pending
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