JP2016530309A5 - - Google Patents
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- Publication number
- JP2016530309A5 JP2016530309A5 JP2016542014A JP2016542014A JP2016530309A5 JP 2016530309 A5 JP2016530309 A5 JP 2016530309A5 JP 2016542014 A JP2016542014 A JP 2016542014A JP 2016542014 A JP2016542014 A JP 2016542014A JP 2016530309 A5 JP2016530309 A5 JP 2016530309A5
- Authority
- JP
- Japan
- Prior art keywords
- oral composition
- agent
- oral
- buffer
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 70
- 239000003795 chemical substances by application Substances 0.000 claims description 14
- 229920001577 copolymer Polymers 0.000 claims description 14
- 210000000214 mouth Anatomy 0.000 claims description 13
- 230000001680 brushing effect Effects 0.000 claims description 12
- 239000013543 active substance Substances 0.000 claims description 11
- 239000012528 membrane Substances 0.000 claims description 10
- 239000007853 buffer solution Substances 0.000 claims description 9
- 230000007935 neutral effect Effects 0.000 claims description 9
- 239000000178 monomer Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000006184 cosolvent Substances 0.000 claims description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- 239000000159 acid neutralizing agent Substances 0.000 claims description 6
- 239000008363 phosphate buffer Substances 0.000 claims description 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 4
- 208000006558 Dental Calculus Diseases 0.000 claims description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical group CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 4
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 4
- 239000000872 buffer Substances 0.000 claims description 4
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 claims description 4
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 4
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical group [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- BHHYHSUAOQUXJK-UHFFFAOYSA-L zinc fluoride Chemical compound F[Zn]F BHHYHSUAOQUXJK-UHFFFAOYSA-L 0.000 claims description 4
- -1 ethylene glycol esters alcohols Chemical class 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 2
- 206010006326 Breath odour Diseases 0.000 claims description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
- 229940090898 Desensitizer Drugs 0.000 claims description 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 2
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-L Phosphate ion(2-) Chemical compound OP([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-L 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 239000012190 activator Substances 0.000 claims description 2
- 125000005233 alkylalcohol group Chemical group 0.000 claims description 2
- 239000000730 antalgic agent Substances 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 230000000170 anti-cariogenic effect Effects 0.000 claims description 2
- 230000003610 anti-gingivitis Effects 0.000 claims description 2
- 230000002882 anti-plaque Effects 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims description 2
- 229940062672 calcium dihydrogen phosphate Drugs 0.000 claims description 2
- 229910001634 calcium fluoride Inorganic materials 0.000 claims description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 2
- 229960001714 calcium phosphate Drugs 0.000 claims description 2
- 239000001506 calcium phosphate Substances 0.000 claims description 2
- 235000011010 calcium phosphates Nutrition 0.000 claims description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims description 2
- 150000007942 carboxylates Chemical class 0.000 claims description 2
- 239000004091 cariogenic agent Substances 0.000 claims description 2
- 150000001805 chlorine compounds Chemical class 0.000 claims description 2
- 239000003086 colorant Substances 0.000 claims description 2
- 229940124447 delivery agent Drugs 0.000 claims description 2
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-M dihydrogenphosphate Chemical compound OP(O)([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-M 0.000 claims description 2
- 239000007884 disintegrant Substances 0.000 claims description 2
- 239000000796 flavoring agent Substances 0.000 claims description 2
- 229910052731 fluorine Inorganic materials 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- 239000003193 general anesthetic agent Substances 0.000 claims description 2
- 235000011187 glycerol Nutrition 0.000 claims description 2
- 150000004679 hydroxides Chemical class 0.000 claims description 2
- 235000019691 monocalcium phosphate Nutrition 0.000 claims description 2
- 230000003239 periodontal effect Effects 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 230000000395 remineralizing effect Effects 0.000 claims description 2
- 210000003296 saliva Anatomy 0.000 claims description 2
- 239000011775 sodium fluoride Substances 0.000 claims description 2
- 235000013024 sodium fluoride Nutrition 0.000 claims description 2
- FVRNDBHWWSPNOM-UHFFFAOYSA-L strontium fluoride Chemical compound [F-].[F-].[Sr+2] FVRNDBHWWSPNOM-UHFFFAOYSA-L 0.000 claims description 2
- 229910001637 strontium fluoride Inorganic materials 0.000 claims description 2
- 238000013268 sustained release Methods 0.000 claims description 2
- 239000012730 sustained-release form Substances 0.000 claims description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 2
- 230000002087 whitening effect Effects 0.000 claims description 2
- 210000005239 tubule Anatomy 0.000 claims 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 159000000007 calcium salts Chemical group 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 description 1
- 229920003149 Eudragit® E 100 Polymers 0.000 description 1
- 229920003155 Eudragit® RL 100 Polymers 0.000 description 1
- 229920003159 Eudragit® RS 100 Polymers 0.000 description 1
- NEDGUIRITORSKL-UHFFFAOYSA-N butyl 2-methylprop-2-enoate;2-(dimethylamino)ethyl 2-methylprop-2-enoate;methyl 2-methylprop-2-enoate Chemical group COC(=O)C(C)=C.CCCCOC(=O)C(C)=C.CN(C)CCOC(=O)C(C)=C NEDGUIRITORSKL-UHFFFAOYSA-N 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 150000004673 fluoride salts Chemical class 0.000 description 1
- 150000002222 fluorine compounds Chemical group 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361876441P | 2013-09-11 | 2013-09-11 | |
| US61/876,441 | 2013-09-11 | ||
| PCT/US2014/054074 WO2015038400A1 (en) | 2013-09-11 | 2014-09-04 | Oral compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016530309A JP2016530309A (ja) | 2016-09-29 |
| JP2016530309A5 true JP2016530309A5 (https=) | 2017-10-19 |
| JP6480458B2 JP6480458B2 (ja) | 2019-03-13 |
Family
ID=51656051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016542014A Active JP6480458B2 (ja) | 2013-09-11 | 2014-09-04 | 口腔用組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20160220472A1 (https=) |
| EP (1) | EP3043869B1 (https=) |
| JP (1) | JP6480458B2 (https=) |
| CN (1) | CN105530998B (https=) |
| RU (1) | RU2646501C2 (https=) |
| WO (1) | WO2015038400A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105530999B (zh) | 2013-09-11 | 2019-08-16 | 3M创新有限公司 | 口腔组合物、牙齿结构以及递送口腔组合物的方法 |
| AU2018330662B2 (en) * | 2017-09-08 | 2021-12-02 | Solventum Intellectual Properties Company | Aqueous oral care fluoride treatment compositions, and methods |
| EP3892336A1 (en) | 2017-09-29 | 2021-10-13 | 3M Innovative Properties Co. | Aqueous oral care fluoride treatment compositions, and methods |
| JP2019115647A (ja) * | 2017-12-26 | 2019-07-18 | 株式会社広栄社 | アルカリ性メラミンフォーム製品とその製造方法。 |
| CN113226272A (zh) * | 2018-10-16 | 2021-08-06 | 高露洁-棕榄公司 | 口腔护理组合物和其方法 |
| US11154487B2 (en) | 2018-10-16 | 2021-10-26 | Colgate-Palmolive Company | Oral care compositions and methods for the same |
| US11260016B2 (en) | 2018-10-16 | 2022-03-01 | Colgate-Palmolive Company | Oral care compositions and methods for the same |
| WO2020081050A1 (en) * | 2018-10-16 | 2020-04-23 | Colgate-Palmolive Company | Oral care compositions and methods for the same |
| US11173105B2 (en) | 2018-10-16 | 2021-11-16 | Colgate-Palmolive Company | Oral care compositions and methods for the same |
| CN113015516A (zh) * | 2018-10-16 | 2021-06-22 | 高露洁-棕榄公司 | 口腔护理组合物及用于其的方法 |
| EP4180031B1 (en) * | 2020-07-13 | 2025-10-22 | Kirin Holdings Kabushiki Kaisha | Film coated tablet |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| CA3216359A1 (en) | 2021-04-07 | 2022-10-13 | Battelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| WO2022243767A1 (en) | 2021-05-18 | 2022-11-24 | 3M Innovative Properties Company | Dental appliance with non-aqueous composition |
| US20220394979A1 (en) * | 2021-06-14 | 2022-12-15 | Pinnacle Environmental Solutions, LLC | Multipurpose disinfection solutions |
| AU2024353375A1 (en) | 2023-09-29 | 2026-04-09 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
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| US4134935A (en) * | 1971-08-12 | 1979-01-16 | Bayer Aktiengesellschaft | Dental varnishes |
| US4883534A (en) | 1983-05-11 | 1989-11-28 | University Of Toronto Innovations Foundations | Benzoin antimicrobial dental varnishes |
| JPS61289006A (ja) | 1985-06-17 | 1986-12-19 | Sunstar Inc | 歯科用接着性コ−テイングベ−ス組成物 |
| JPH0729915B2 (ja) * | 1986-02-01 | 1995-04-05 | 帝國製薬株式会社 | シ−ト状口腔内貼付剤 |
| US5288480A (en) | 1987-01-30 | 1994-02-22 | Colgate-Palmolive Co. | Antiplaque antibacterial oral composition |
| JPS6477896A (en) | 1987-09-18 | 1989-03-23 | Ito Seitetsushiyo Kk | Electrode extension connection device in electric furnace |
| US5160737A (en) | 1988-05-03 | 1992-11-03 | Perio Products Ltd. | Liquid polymer composition, and method of use |
| US5438076A (en) | 1988-05-03 | 1995-08-01 | Perio Products, Ltd. | Liquid polymer composition, and method of use |
| US5330746A (en) | 1988-05-03 | 1994-07-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Dental varnish composition, and method of use |
| DE3827561C1 (https=) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| US5249206A (en) | 1989-08-11 | 1993-09-28 | International Business Machines Corporation | Fault-tolerant clock for multicomputer complex |
| WO1994004126A2 (en) * | 1992-08-18 | 1994-03-03 | Unilever N.V. | Polymeric anticalculus agents |
| US5521293A (en) | 1992-11-25 | 1996-05-28 | Lever Brothers Company, Division Of Conopco, Inc. | Heteroatom containing alkyl aldonamide compounds as superior foaming, more soluble nonionic surfactants and a process for their manufacture |
| JP3022039B2 (ja) * | 1993-03-05 | 2000-03-15 | サンスター株式会社 | 歯牙着色防止用口腔用組成物 |
| JPH08325128A (ja) * | 1995-03-31 | 1996-12-10 | Sunstar Inc | 口腔用長期滞留型基剤およびそれを用いた組成物 |
| JP3590438B2 (ja) * | 1995-03-31 | 2004-11-17 | サンスター株式会社 | 口腔用組成物 |
| DE19629167C2 (de) * | 1996-07-19 | 2000-05-04 | Einhorn Apotheke Dr Guenther H | Feste orale, antikariogene Zusammensetzung in Form einer Lutschtablette zum Reinigen der Mundhöhle und Zähne |
| IT1302638B1 (it) * | 1998-10-09 | 2000-09-29 | A C R Applied Coating Res Sa | Cerotti transdermici a base di cumarina o meliloto |
| EP1307173B1 (de) | 2000-08-07 | 2008-10-15 | S & C Polymer Silicon- und Composite-Spezialitäten GmbH | Haftender fluoridlack |
| EP1322276B1 (en) * | 2000-09-26 | 2006-03-29 | Thomas R. Patacca | Tooth coating composition |
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| US20050063921A1 (en) | 2003-09-19 | 2005-03-24 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Oral composition |
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| US20060024246A1 (en) * | 2004-07-29 | 2006-02-02 | Prithwiraj Maitra | Oral care compositions with film forming polymers |
| JP2009522003A (ja) | 2005-12-29 | 2009-06-11 | スリーエム イノベイティブ プロパティズ カンパニー | 発泡性歯科用組成物及び方法 |
| BRPI0714868A2 (pt) | 2006-09-01 | 2013-05-28 | Smithkline Beecham Corp | composiÇço para tratamento de dentadura |
| EP2180873B1 (en) | 2007-07-25 | 2018-04-11 | 3M Innovative Properties Company | Therapeutic dental composition for use in the inhibition of biofilm formation in the oral cavity. |
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| EP2296577A1 (en) | 2008-06-09 | 2011-03-23 | Densys Ltd. | Intra-oral surface non-aqueous hydrophobic coating composition and method |
| RU2549979C2 (ru) | 2008-06-27 | 2015-05-10 | НоваМин Текнолоджи, Инк. | Композиция и способ увеличения поглощения фторида с использованием биоактивного стекла |
| US8632754B2 (en) * | 2009-08-03 | 2014-01-21 | Mcneil-Ppc, Inc. | Tooth sensitivity treatment compositions |
| EP2485713B1 (en) * | 2009-10-05 | 2018-09-26 | Yissum Research Development Company of the Hebrew University of Jerusalem | Liquid precursor compositions and uses thereof for a ph-dependant sustained release treatment of oral disorders |
| TWI499430B (zh) * | 2009-12-17 | 2015-09-11 | 美國棕欖公司 | 抗侵蝕的牙膏組成物 |
| EP2584994A1 (en) | 2010-06-24 | 2013-05-01 | 3M Innovative Properties Company | Aqueous composition suitable for intra-oral scanning methods |
| RU2517142C2 (ru) | 2012-04-27 | 2014-05-27 | Общество с ограниченной ответственностью "Инновационные полимерные адгезивы" | Гидрофильный чувствительный к давлению биоадгезив с целенаправленной адгезией к зубам и композиция для ухода за зубами на его основе |
| CN102846488A (zh) * | 2012-09-17 | 2013-01-02 | 江苏隆力奇生物科技股份有限公司 | 一种牙齿美化液 |
| CN105530999B (zh) | 2013-09-11 | 2019-08-16 | 3M创新有限公司 | 口腔组合物、牙齿结构以及递送口腔组合物的方法 |
| US20160213575A1 (en) | 2013-09-11 | 2016-07-28 | 3M Innovative Properties Company | Coating compositions, dental structures thereof and methods for generating contrast |
| CN105722498B (zh) | 2013-11-14 | 2022-09-02 | 皇家飞利浦有限公司 | 用于施用口腔护理剂的系统和方法 |
| EP3131525A1 (en) | 2014-04-14 | 2017-02-22 | 3M Innovative Properties Company | Oral compositions |
-
2014
- 2014-09-04 RU RU2016110110A patent/RU2646501C2/ru not_active IP Right Cessation
- 2014-09-04 EP EP14777952.4A patent/EP3043869B1/en active Active
- 2014-09-04 WO PCT/US2014/054074 patent/WO2015038400A1/en not_active Ceased
- 2014-09-04 CN CN201480049513.XA patent/CN105530998B/zh active Active
- 2014-09-04 JP JP2016542014A patent/JP6480458B2/ja active Active
- 2014-09-04 US US14/917,442 patent/US20160220472A1/en not_active Abandoned
-
2019
- 2019-09-27 US US16/585,341 patent/US10772821B2/en active Active
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