JP2016519955A - 選別可能な精子を有する動物を作製するための遺伝子技術 - Google Patents

選別可能な精子を有する動物を作製するための遺伝子技術 Download PDF

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Publication number
JP2016519955A
JP2016519955A JP2016516662A JP2016516662A JP2016519955A JP 2016519955 A JP2016519955 A JP 2016519955A JP 2016516662 A JP2016516662 A JP 2016516662A JP 2016516662 A JP2016516662 A JP 2016516662A JP 2016519955 A JP2016519955 A JP 2016519955A
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Prior art keywords
sperm
marker
animal
cells
chromosome
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JP2016516662A
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Japanese (ja)
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JP2016519955A5 (https=
Inventor
ダニエル・エフ・カールソン
スコット・シー・ファーレンクラッグ
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Recombinetics Inc
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Recombinetics Inc
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Application filed by Recombinetics Inc filed Critical Recombinetics Inc
Publication of JP2016519955A publication Critical patent/JP2016519955A/ja
Publication of JP2016519955A5 publication Critical patent/JP2016519955A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
JP2016516662A 2013-05-31 2014-04-29 選別可能な精子を有する動物を作製するための遺伝子技術 Pending JP2016519955A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361829672P 2013-05-31 2013-05-31
US61/829,672 2013-05-31
US201361870586P 2013-08-27 2013-08-27
US61/870,586 2013-08-27
PCT/US2014/035851 WO2014193584A2 (en) 2013-05-31 2014-04-29 Genetic techniques for making animals with sortable sperm

Publications (2)

Publication Number Publication Date
JP2016519955A true JP2016519955A (ja) 2016-07-11
JP2016519955A5 JP2016519955A5 (https=) 2017-06-15

Family

ID=51986778

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016516662A Pending JP2016519955A (ja) 2013-05-31 2014-04-29 選別可能な精子を有する動物を作製するための遺伝子技術

Country Status (13)

Country Link
US (1) US20140359795A1 (https=)
EP (1) EP3003021A4 (https=)
JP (1) JP2016519955A (https=)
KR (1) KR20160015333A (https=)
CN (1) CN105658050A (https=)
AP (1) AP2015008966A0 (https=)
AU (1) AU2014272107A1 (https=)
BR (1) BR112015029905A2 (https=)
CA (1) CA2913412A1 (https=)
MX (1) MX2015016383A (https=)
PH (1) PH12015502646A1 (https=)
RU (1) RU2015156824A (https=)
WO (1) WO2014193584A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3456831T3 (da) 2013-04-16 2021-09-06 Regeneron Pharma Målrettet modifikation af rottegenom
US20140359796A1 (en) * 2013-05-31 2014-12-04 Recombinetics, Inc. Genetically sterile animals
US10779518B2 (en) 2013-10-25 2020-09-22 Livestock Improvement Corporation Limited Genetic markers and uses therefor
CN106459995B (zh) 2013-11-07 2020-02-21 爱迪塔斯医药有限公司 使用统治型gRNA的CRISPR相关方法和组合物
US10787684B2 (en) * 2013-11-19 2020-09-29 President And Fellows Of Harvard College Large gene excision and insertion
KR102170502B1 (ko) 2013-12-11 2020-10-28 리제너론 파마슈티칼스 인코포레이티드 게놈의 표적화된 변형을 위한 방법 및 조성물
BR112016024945A2 (pt) 2014-04-28 2017-10-24 Recombinetics Inc edição de gene multiplex em suínos
SI3161128T1 (sl) 2014-06-26 2019-02-28 Regeneron Pharmaceuticals, Inc. Postopki in sestavki za ciljano genetsko spremembo in postopki uporabe
KR102531016B1 (ko) 2014-11-21 2023-05-10 리제너론 파마슈티칼스 인코포레이티드 쌍 형성된 가이드 rna를 사용하는 표적화된 유전자 변형을 위한 방법 및 조성물
EP3303585A4 (en) 2015-06-03 2018-10-31 Board of Regents of the University of Nebraska Dna editing using single-stranded dna
CN107315092B (zh) * 2017-07-11 2019-03-19 上海市第一人民医院 一种快速评估睾丸生精功能的免疫荧光染色法及其试剂盒
WO2020102565A2 (en) * 2018-11-14 2020-05-22 Flagship Pioneering Innovations V, Inc. Systems and methods for nondestructive testing of gametes
CN111500530A (zh) * 2020-04-30 2020-08-07 延安大学 一种通用型动物精子分选方法及x精子质控方法
CN114015705A (zh) * 2021-11-28 2022-02-08 华中科技大学同济医学院附属协和医院 一种小鼠体外受精繁育性别选择方法
WO2024249570A2 (en) * 2023-06-02 2024-12-05 New York University Single-sex chicken with toxin-antitoxin system

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003516134A (ja) * 1999-12-07 2003-05-13 ユニバーシティ オブ グェルフ 性染色体特異的タンパク質、種特異的および精子特異的タンパク質、ならびにそれらの同定および単離の方法
JP2003518927A (ja) * 1999-12-27 2003-06-17 チェニュー・リュウ 性染色体に対するトランス遺伝子の標的化による子孫の性別比の制御
US20050081256A1 (en) * 2001-03-22 2005-04-14 Forsberg Erik J. Sex- specific selection of sperm from transgenic animals
JP2005137367A (ja) * 2003-10-14 2005-06-02 Japan Science & Technology Agency Ｙ染色体標識トランスジェニック非ヒト動物
JP2008521441A (ja) * 2004-12-03 2008-06-26 エンビボ ファーマシューティカルズ インコーポレイテッド 非ヒト動物の性特異的自動化選別
WO2010120518A2 (en) * 2009-04-01 2010-10-21 Biocern, Inc. Sperm cell separation methods and compositions containing sperm cell targeting ligands for use therein

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
EP1129205A1 (en) * 1998-11-13 2001-09-05 Cedars-Sinai Medical Center Transfection of male germ cells for generation of selectable transgenic stem cells
GB9916810D0 (en) * 1999-07-16 1999-09-22 Cancer Res Campaign Tech Killing cells
CN1291010C (zh) * 2000-02-24 2006-12-20 马萨诸塞大学 只生育单一性别后代的哺乳动物的生产
CN1313061C (zh) * 2002-03-11 2007-05-02 刘凤鸣 一种动物精子的性别分选方法
CN101014350A (zh) * 2004-03-29 2007-08-08 孟山都技术公司 用于授精的精子悬浮液
EP2470557A1 (en) * 2009-08-28 2012-07-04 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Genetic vasectomy by overexpression of prml-egfp fusion protein in spermatids
MX363013B (es) * 2011-02-25 2019-03-04 Recombinetics Inc Animales genéticamente modificados y métodos para su obtención.
CN102199606B (zh) * 2011-03-09 2012-12-26 塔里木大学 一种筛选非人哺乳动物xy精子差异表达基因的方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003516134A (ja) * 1999-12-07 2003-05-13 ユニバーシティ オブ グェルフ 性染色体特異的タンパク質、種特異的および精子特異的タンパク質、ならびにそれらの同定および単離の方法
JP2003518927A (ja) * 1999-12-27 2003-06-17 チェニュー・リュウ 性染色体に対するトランス遺伝子の標的化による子孫の性別比の制御
US20050081256A1 (en) * 2001-03-22 2005-04-14 Forsberg Erik J. Sex- specific selection of sperm from transgenic animals
JP2005137367A (ja) * 2003-10-14 2005-06-02 Japan Science & Technology Agency Ｙ染色体標識トランスジェニック非ヒト動物
JP2008521441A (ja) * 2004-12-03 2008-06-26 エンビボ ファーマシューティカルズ インコーポレイテッド 非ヒト動物の性特異的自動化選別
WO2010120518A2 (en) * 2009-04-01 2010-10-21 Biocern, Inc. Sperm cell separation methods and compositions containing sperm cell targeting ligands for use therein

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. GENET. GENOMICS, AVAILABLE ONLINE 2013.04.12, VOL.40, P.281-289, JPN6018011569, ISSN: 0003946066 *

Also Published As

Publication number Publication date
MX2015016383A (es) 2016-09-29
PH12015502646A1 (en) 2016-03-07
AU2014272107A1 (en) 2016-01-21
BR112015029905A2 (pt) 2017-09-26
US20140359795A1 (en) 2014-12-04
EP3003021A4 (en) 2016-11-02
KR20160015333A (ko) 2016-02-12
CA2913412A1 (en) 2014-12-04
AP2015008966A0 (en) 2015-12-31
EP3003021A2 (en) 2016-04-13
CN105658050A (zh) 2016-06-08
WO2014193584A3 (en) 2015-08-06
WO2014193584A2 (en) 2014-12-04
RU2015156824A (ru) 2017-07-05

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