JP2016517870A5 - - Google Patents
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- Publication number
- JP2016517870A5 JP2016517870A5 JP2016510811A JP2016510811A JP2016517870A5 JP 2016517870 A5 JP2016517870 A5 JP 2016517870A5 JP 2016510811 A JP2016510811 A JP 2016510811A JP 2016510811 A JP2016510811 A JP 2016510811A JP 2016517870 A5 JP2016517870 A5 JP 2016517870A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- layer
- polymer
- highly water
- eluting article
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940079593 drug Drugs 0.000 claims description 69
- 239000003814 drug Substances 0.000 claims description 69
- 229920000642 polymer Polymers 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 22
- 230000002209 hydrophobic effect Effects 0.000 claims description 19
- 239000000758 substrate Substances 0.000 claims description 19
- 239000007864 aqueous solution Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 125000005647 linker group Chemical group 0.000 claims description 12
- 239000011248 coating agent Substances 0.000 claims description 11
- 238000000576 coating method Methods 0.000 claims description 11
- 229920001444 polymaleic acid Polymers 0.000 claims description 10
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 claims description 10
- 229920001296 polysiloxane Polymers 0.000 claims description 7
- 229920002367 Polyisobutene Polymers 0.000 claims description 6
- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 5
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 5
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 5
- 125000005373 siloxane group Chemical group [SiH2](O*)* 0.000 claims description 5
- 229910001961 silver nitrate Inorganic materials 0.000 claims description 5
- 239000004793 Polystyrene Substances 0.000 claims description 4
- 229920001400 block copolymer Polymers 0.000 claims description 4
- 229920002223 polystyrene Polymers 0.000 claims description 4
- 239000011976 maleic acid Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 4
- 239000011230 binding agent Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 230000004308 accommodation Effects 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 239000012457 nonaqueous media Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000003618 dip coating Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361815910P | 2013-04-25 | 2013-04-25 | |
| US61/815,910 | 2013-04-25 | ||
| PCT/US2014/035527 WO2014176545A1 (en) | 2013-04-25 | 2014-04-25 | Coatings for controlled release of highly water soluble drugs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517870A JP2016517870A (ja) | 2016-06-20 |
| JP2016517870A5 true JP2016517870A5 (enExample) | 2017-11-24 |
| JP6255483B2 JP6255483B2 (ja) | 2017-12-27 |
Family
ID=51792417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016510811A Expired - Fee Related JP6255483B2 (ja) | 2013-04-25 | 2014-04-25 | 高度に水溶性な薬物の制御放出のためのコーティング |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9814805B2 (enExample) |
| EP (1) | EP2988730A4 (enExample) |
| JP (1) | JP6255483B2 (enExample) |
| CN (1) | CN105283169B (enExample) |
| AU (1) | AU2014256955B2 (enExample) |
| CA (1) | CA2909069C (enExample) |
| WO (1) | WO2014176545A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6255483B2 (ja) * | 2013-04-25 | 2017-12-27 | イノベイティブ サーフェイス テクノロジーズ， インコーポレイテッド | 高度に水溶性な薬物の制御放出のためのコーティング |
| US10744233B2 (en) | 2016-02-24 | 2020-08-18 | Innovative Surface Technologies, Inc. | Crystallization inhibitor compositions for implantable urological devices |
| CN110709174A (zh) | 2017-06-22 | 2020-01-17 | 宝洁公司 | 包括水溶性层和气相沉积有机涂层的膜 |
| CN110719968A (zh) | 2017-06-22 | 2020-01-21 | 宝洁公司 | 包括水溶性层和气相沉积无机涂层的膜 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| US5271945A (en) | 1988-07-05 | 1993-12-21 | Takeda Chemical Industries, Ltd. | Sustained release microcapsule for water soluble drug |
| US6120536A (en) | 1995-04-19 | 2000-09-19 | Schneider (Usa) Inc. | Medical devices with long term non-thrombogenic coatings |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US5714360A (en) | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| US5980972A (en) | 1996-12-20 | 1999-11-09 | Schneider (Usa) Inc | Method of applying drug-release coatings |
| US6790228B2 (en) | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US7682647B2 (en) * | 1999-09-03 | 2010-03-23 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of a drug eluting implantable medical device |
| US6278018B1 (en) | 1999-12-14 | 2001-08-21 | Surmodics, Inc. | Surface coating agents |
| EP1531875B1 (en) | 2002-08-13 | 2010-03-03 | Medtronic, Inc. | Active agent delivery system including a poly(ethylene-co-(meth)acrylate), medical device, and method |
| AU2003285195A1 (en) | 2002-11-08 | 2004-06-03 | Innovational Holdings, Llc | Method and apparatus for treating vulnerable artherosclerotic plaque |
| ATE476960T1 (de) | 2003-05-02 | 2010-08-15 | Surmodics Inc | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges |
| US7811274B2 (en) | 2003-05-07 | 2010-10-12 | Portaero, Inc. | Method for treating chronic obstructive pulmonary disease |
| US20050100577A1 (en) * | 2003-11-10 | 2005-05-12 | Parker Theodore L. | Expandable medical device with beneficial agent matrix formed by a multi solvent system |
| CN1964748A (zh) * | 2004-04-06 | 2007-05-16 | 苏莫迪克斯公司 | 用于生物活性剂的涂料组合物 |
| US7901451B2 (en) * | 2004-09-24 | 2011-03-08 | Biosensors International Group, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
| US20080075753A1 (en) | 2006-09-25 | 2008-03-27 | Chappa Ralph A | Multi-layered coatings and methods for controlling elution of active agents |
| US8163034B2 (en) | 2007-05-11 | 2012-04-24 | Portaero, Inc. | Methods and devices to create a chemically and/or mechanically localized pleurodesis |
| WO2013033159A1 (en) * | 2011-08-31 | 2013-03-07 | The Trustees Of Columbia University In The City Of New York | Reduction of biofilms on medical devices |
| WO2009060322A2 (en) | 2007-10-30 | 2009-05-14 | Uti Limited Partnership | Method and system for sustained-release of sclerosing agent |
| US8496954B2 (en) | 2008-04-18 | 2013-07-30 | Surmodics, Inc. | Coating systems for the controlled delivery of hydrophilic bioactive agents |
| WO2010033482A1 (en) * | 2008-09-19 | 2010-03-25 | Innovative Surface Technologies, Inc. | Drug eluting superhydrophobic coatings |
| AU2010339654B2 (en) * | 2009-12-21 | 2014-07-17 | Innovative Surface Technologies, Inc. | Coating agents and coated articles |
| US20110159072A1 (en) | 2009-12-30 | 2011-06-30 | Surmodics, Inc. | Controlled release matrix |
| WO2012058274A2 (en) | 2010-10-26 | 2012-05-03 | Surmodics, Inc. | Coatings and methods for controlled elution of hydrophilic active agents |
| US20120302950A1 (en) | 2011-05-26 | 2012-11-29 | Carefusion 2200, Inc. | Active pleurodesis catheter |
| US8697112B2 (en) * | 2011-07-08 | 2014-04-15 | Covalon Technologies | Method for treating a surface with a coating comprising a microencapsulated therapeutic agent and device with treated surface |
| JP6255483B2 (ja) * | 2013-04-25 | 2017-12-27 | イノベイティブ サーフェイス テクノロジーズ， インコーポレイテッド | 高度に水溶性な薬物の制御放出のためのコーティング |
-
2014
- 2014-04-25 JP JP2016510811A patent/JP6255483B2/ja not_active Expired - Fee Related
- 2014-04-25 EP EP14788719.4A patent/EP2988730A4/en active Pending
- 2014-04-25 CA CA2909069A patent/CA2909069C/en active Active
- 2014-04-25 AU AU2014256955A patent/AU2014256955B2/en not_active Ceased
- 2014-04-25 WO PCT/US2014/035527 patent/WO2014176545A1/en not_active Ceased
- 2014-04-25 US US14/786,842 patent/US9814805B2/en active Active
- 2014-04-25 CN CN201480028712.2A patent/CN105283169B/zh not_active Expired - Fee Related
-
2017
- 2017-10-11 US US15/730,006 patent/US10098989B2/en active Active
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