JP2016517856A5 - - Google Patents
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- Publication number
- JP2016517856A5 JP2016517856A5 JP2016509014A JP2016509014A JP2016517856A5 JP 2016517856 A5 JP2016517856 A5 JP 2016517856A5 JP 2016509014 A JP2016509014 A JP 2016509014A JP 2016509014 A JP2016509014 A JP 2016509014A JP 2016517856 A5 JP2016517856 A5 JP 2016517856A5
- Authority
- JP
- Japan
- Prior art keywords
- stroke
- composition according
- composition
- patient
- aminopyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 45
- 208000006011 Stroke Diseases 0.000 claims 22
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 14
- 208000035475 disorder Diseases 0.000 claims 14
- 238000011282 treatment Methods 0.000 claims 9
- 150000003927 aminopyridines Chemical class 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 5
- 210000001841 basilar artery Anatomy 0.000 claims 4
- NUKYPUAOHBNCPY-UHFFFAOYSA-N 4-aminopyridine Chemical group NC1=CC=NC=C1 NUKYPUAOHBNCPY-UHFFFAOYSA-N 0.000 claims 3
- 208000013140 Sensorimotor disease Diseases 0.000 claims 3
- 238000013268 sustained release Methods 0.000 claims 3
- 239000012730 sustained-release form Substances 0.000 claims 3
- 210000002385 vertebral artery Anatomy 0.000 claims 3
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 2
- 210000004004 carotid artery internal Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229960004979 fampridine Drugs 0.000 claims 2
- 210000003141 lower extremity Anatomy 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 206010048963 Basilar artery occlusion Diseases 0.000 claims 1
- 206010013887 Dysarthria Diseases 0.000 claims 1
- 206010017577 Gait disturbance Diseases 0.000 claims 1
- 208000032382 Ischaemic stroke Diseases 0.000 claims 1
- 208000026025 Muscle tone disease Diseases 0.000 claims 1
- 210000002551 anterior cerebral artery Anatomy 0.000 claims 1
- 201000007301 anterior cerebral artery infarction Diseases 0.000 claims 1
- 238000003287 bathing Methods 0.000 claims 1
- 210000003414 extremity Anatomy 0.000 claims 1
- 230000003370 grooming effect Effects 0.000 claims 1
- 230000018984 mastication Effects 0.000 claims 1
- 238000010077 mastication Methods 0.000 claims 1
- 230000004899 motility Effects 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 210000003388 posterior cerebral artery Anatomy 0.000 claims 1
- 201000005894 posterior cerebral artery infarction Diseases 0.000 claims 1
- ZZYXNRREDYWPLN-UHFFFAOYSA-N pyridine-2,3-diamine Chemical compound NC1=CC=CN=C1N ZZYXNRREDYWPLN-UHFFFAOYSA-N 0.000 claims 1
- 239000007916 tablet composition Substances 0.000 claims 1
- 210000001738 temporomandibular joint Anatomy 0.000 claims 1
- 210000001364 upper extremity Anatomy 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361812239P | 2013-04-15 | 2013-04-15 | |
| US61/812,239 | 2013-04-15 | ||
| US201361816551P | 2013-04-26 | 2013-04-26 | |
| US201361816592P | 2013-04-26 | 2013-04-26 | |
| US61/816,592 | 2013-04-26 | ||
| US61/816,551 | 2013-04-26 | ||
| PCT/US2014/033974 WO2014172266A1 (en) | 2013-04-15 | 2014-04-14 | Methods for treating sensorimotor impairments associated with certain types of stroke using aminopyridines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018100944A Division JP2018127497A (ja) | 2013-04-15 | 2018-05-25 | アミノピリジンを使用した、ある種の卒中に関連した感覚運動障害を治療するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016517856A JP2016517856A (ja) | 2016-06-20 |
| JP2016517856A5 true JP2016517856A5 (enExample) | 2017-06-08 |
Family
ID=50841951
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509014A Pending JP2016517856A (ja) | 2013-04-15 | 2014-04-14 | アミノピリジンを使用した、ある種の卒中に関連した感覚運動障害を治療するための方法 |
| JP2018100944A Pending JP2018127497A (ja) | 2013-04-15 | 2018-05-25 | アミノピリジンを使用した、ある種の卒中に関連した感覚運動障害を治療するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018100944A Pending JP2018127497A (ja) | 2013-04-15 | 2018-05-25 | アミノピリジンを使用した、ある種の卒中に関連した感覚運動障害を治療するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20160058743A1 (enExample) |
| EP (3) | EP3243516A1 (enExample) |
| JP (2) | JP2016517856A (enExample) |
| AU (1) | AU2014254164A1 (enExample) |
| CA (1) | CA2909527A1 (enExample) |
| HK (1) | HK1221666A1 (enExample) |
| WO (1) | WO2014172266A1 (enExample) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989009600A1 (en) | 1988-04-08 | 1989-10-19 | Massachusetts Institute Of Technology | Method and composition for treating neurological disorders |
| IE82916B1 (en) | 1990-11-02 | 2003-06-11 | Elan Corp Plc | Formulations and their use in the treatment of neurological diseases |
| US5952357A (en) | 1993-12-23 | 1999-09-14 | Cornell Research Foundation, Inc. | Treating diseases of the anterior horn cells |
| US8007826B2 (en) | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
| US8354437B2 (en) | 2004-04-09 | 2013-01-15 | Acorda Therapeutics, Inc. | Method of using sustained release aminopyridine compositions |
| WO2007097929A1 (en) * | 2006-02-16 | 2007-08-30 | Fibrogen, Inc. | Compounds and methods for treatment of stroke |
| US20100049236A1 (en) * | 2008-08-25 | 2010-02-25 | The Ohio State University Research Foundation | Method for testing an agent for strokes in humans with a non-human stroke model |
| JO3348B1 (ar) * | 2009-08-11 | 2019-03-13 | Acorda Therapeutics Inc | استخدام 4- بايريدين امينو لتحسين الادراك العصبي و/او التلف النفسي لدى مرضى يعانون من نقص النُخاعين وغير ذلك من امراض الجهاز العصبي |
| EP2667869A1 (en) * | 2011-01-28 | 2013-12-04 | Acorda Therapeutics, Inc. | Use of potassium channel blockers to treat cerebral palsy |
| TWI592156B (zh) * | 2011-10-04 | 2017-07-21 | 艾可達醫療公司 | 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 |
-
2014
- 2014-04-14 WO PCT/US2014/033974 patent/WO2014172266A1/en not_active Ceased
- 2014-04-14 JP JP2016509014A patent/JP2016517856A/ja active Pending
- 2014-04-14 CA CA2909527A patent/CA2909527A1/en not_active Abandoned
- 2014-04-14 HK HK16109985.0A patent/HK1221666A1/zh unknown
- 2014-04-14 US US14/784,279 patent/US20160058743A1/en not_active Abandoned
- 2014-04-14 EP EP17158999.7A patent/EP3243516A1/en not_active Withdrawn
- 2014-04-14 EP EP14727113.4A patent/EP2986292A1/en not_active Withdrawn
- 2014-04-14 EP EP18172451.9A patent/EP3427735A1/en not_active Withdrawn
- 2014-04-14 AU AU2014254164A patent/AU2014254164A1/en not_active Abandoned
-
2018
- 2018-05-25 JP JP2018100944A patent/JP2018127497A/ja active Pending
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