JP2016516800A5 - - Google Patents
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- Publication number
- JP2016516800A5 JP2016516800A5 JP2016508192A JP2016508192A JP2016516800A5 JP 2016516800 A5 JP2016516800 A5 JP 2016516800A5 JP 2016508192 A JP2016508192 A JP 2016508192A JP 2016508192 A JP2016508192 A JP 2016508192A JP 2016516800 A5 JP2016516800 A5 JP 2016516800A5
- Authority
- JP
- Japan
- Prior art keywords
- egfr
- egfr antibody
- fucose
- cancer
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13002106 | 2013-04-22 | ||
| EP13002106.6 | 2013-04-22 | ||
| EP13002108.2 | 2013-04-22 | ||
| EP13002108 | 2013-04-22 | ||
| PCT/EP2014/058118 WO2014173886A1 (en) | 2013-04-22 | 2014-04-22 | Anti-cancer treatments with anti-egfr antibodies having a low fucosylation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016516800A JP2016516800A (ja) | 2016-06-09 |
| JP2016516800A5 true JP2016516800A5 (OSRAM) | 2017-05-25 |
Family
ID=50729450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016508192A Withdrawn JP2016516800A (ja) | 2013-04-22 | 2014-04-22 | フコシル化が少ない抗ｅｇｆｒ抗体による抗がん処置 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20160068609A1 (OSRAM) |
| EP (1) | EP2989126A1 (OSRAM) |
| JP (1) | JP2016516800A (OSRAM) |
| KR (1) | KR20150144804A (OSRAM) |
| CN (1) | CN105229030A (OSRAM) |
| AU (1) | AU2014257650A1 (OSRAM) |
| BR (1) | BR112015025955A2 (OSRAM) |
| CA (1) | CA2908819A1 (OSRAM) |
| EA (1) | EA201591977A1 (OSRAM) |
| MX (1) | MX2015014773A (OSRAM) |
| SG (1) | SG11201507743XA (OSRAM) |
| WO (1) | WO2014173886A1 (OSRAM) |
| ZA (1) | ZA201507246B (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10478498B2 (en) | 2014-06-20 | 2019-11-19 | Reform Biologics, Llc | Excipient compounds for biopolymer formulations |
| CN105820248A (zh) * | 2015-01-07 | 2016-08-03 | 上海张江生物技术有限公司 | 一种新型抗egfr单克隆抗体的制备方法及应用 |
| CN105399830B (zh) * | 2015-09-08 | 2019-11-19 | 北京天广实生物技术股份有限公司 | 抗egfr人源化单克隆抗体、其制备方法及用途 |
| WO2017120613A1 (en) * | 2016-01-10 | 2017-07-13 | Sorrento Therapeutics, Inc. | Improved safety for treating cancers with a glycosylated chimeric antibody to egfr |
| WO2017188472A1 (ko) * | 2016-04-27 | 2017-11-02 | 주식회사 녹십자 | 표피 성장 인자 수용체에 특이적으로 결합하는 항체를 유효성분으로 포함하는 암의 전이 억제용 약학 조성물 |
| US11649291B2 (en) | 2016-05-24 | 2023-05-16 | Insmed Incorporated | Antibodies and methods of making same |
| US10279048B2 (en) | 2016-07-13 | 2019-05-07 | Reform Biologics, Llc | Stabilizing excipients for therapeutic protein formulations |
| KR101884614B1 (ko) | 2016-10-11 | 2018-08-02 | 신일제약주식회사 | Fab 단편 및 이의 용도 |
| US20200148785A1 (en) * | 2017-03-29 | 2020-05-14 | Glycotope (GmbH) | Pd-l1 and ta-muc1 antibodies |
| SG11201908813QA (en) * | 2017-04-13 | 2019-10-30 | Aduro Biotech Holdings Europe B V | Anti-sirp alpha antibodies |
| JP7678493B2 (ja) * | 2017-05-29 | 2025-05-16 | エクセリクシス， インク． | 癌関連免疫抑制阻害剤 |
| US20210269530A1 (en) * | 2018-05-14 | 2021-09-02 | Harpoon Therapeutics, Inc. | Conditionally activated binding protein comprising a sterically occluded target binding domain |
| US12195544B2 (en) | 2018-09-21 | 2025-01-14 | Harpoon Therapeutics, Inc. | EGFR binding proteins and methods of use |
| JP7493237B2 (ja) * | 2018-11-14 | 2024-05-31 | 学校法人金沢医科大学 | びまん性胃がんを治療するための医薬組成物 |
| CN112300278A (zh) * | 2019-07-25 | 2021-02-02 | 上海交通大学 | 抗人egfr嵌合抗体及其制备方法和用途 |
| AU2021261681A1 (en) * | 2020-04-24 | 2022-12-08 | Merus N.V. | Treatment of cancers with an antibody that binds LGR5 and EGFR |
| CN115960214A (zh) * | 2021-10-12 | 2023-04-14 | 中国科学院分子细胞科学卓越创新中心 | 中和呼吸道合胞病毒的全人抗体的设计及应用 |
| EP4476263A2 (en) * | 2022-02-09 | 2024-12-18 | Dragonfly Therapeutics, Inc. | Pharmaceutical formulations and therapeutic uses of multi-specific binding proteins that bind egfr, nkg2d, and cd16 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101077001B1 (ko) | 1999-01-15 | 2011-10-26 | 제넨테크, 인크. | 효과기 기능이 변화된 폴리펩티드 변이체 |
| AU3672800A (en) | 1999-04-09 | 2000-11-14 | Kyowa Hakko Kogyo Co. Ltd. | Method for controlling the activity of immunologically functional molecule |
| US7029872B2 (en) | 2000-06-28 | 2006-04-18 | Glycofi, Inc | Methods for producing modified glycoproteins |
| ATE430580T1 (de) | 2001-10-25 | 2009-05-15 | Genentech Inc | Glycoprotein-zusammensetzungen |
| WO2003084569A1 (en) | 2002-04-09 | 2003-10-16 | Kyowa Hakko Kogyo Co., Ltd. | Drug containing antibody composition |
| FR2858235B1 (fr) | 2003-07-31 | 2006-02-17 | Lab Francais Du Fractionnement | Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs |
| PT1871805T (pt) * | 2005-02-07 | 2019-12-02 | Roche Glycart Ag | Moléculas de ligação a antigénios que se ligam ao rfce, vetores que as codificam e as suas utilizações |
| KR20150126730A (ko) | 2006-09-10 | 2015-11-12 | 글리코토페 게엠베하 | 항체 발현을 위한 골수성 백혈병 기원의 인간 세포의 용도 |
| WO2011101328A2 (en) * | 2010-02-18 | 2011-08-25 | Roche Glycart Ag | Treatment with a humanized igg class anti egfr antibody and an antibody against insulin like growth factor 1 receptor |
| WO2012020059A1 (en) * | 2010-08-10 | 2012-02-16 | Glycotope Gmbh | Humanized egfr antibodies |
| CN103119064B (zh) * | 2010-08-10 | 2018-09-04 | 葛莱高托普有限公司 | Fab糖基化抗体 |
-
2014
- 2014-04-22 KR KR1020157033309A patent/KR20150144804A/ko not_active Withdrawn
- 2014-04-22 AU AU2014257650A patent/AU2014257650A1/en not_active Abandoned
- 2014-04-22 JP JP2016508192A patent/JP2016516800A/ja not_active Withdrawn
- 2014-04-22 WO PCT/EP2014/058118 patent/WO2014173886A1/en not_active Ceased
- 2014-04-22 MX MX2015014773A patent/MX2015014773A/es unknown
- 2014-04-22 EP EP14724007.1A patent/EP2989126A1/en not_active Withdrawn
- 2014-04-22 BR BR112015025955A patent/BR112015025955A2/pt not_active IP Right Cessation
- 2014-04-22 US US14/784,470 patent/US20160068609A1/en not_active Abandoned
- 2014-04-22 EA EA201591977A patent/EA201591977A1/ru unknown
- 2014-04-22 SG SG11201507743XA patent/SG11201507743XA/en unknown
- 2014-04-22 CA CA2908819A patent/CA2908819A1/en not_active Abandoned
- 2014-04-22 CN CN201480021328.XA patent/CN105229030A/zh active Pending
-
2015
- 2015-09-30 ZA ZA2015/07246A patent/ZA201507246B/en unknown
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