JP2016516072A5 - - Google Patents
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- Publication number
- JP2016516072A5 JP2016516072A5 JP2016503369A JP2016503369A JP2016516072A5 JP 2016516072 A5 JP2016516072 A5 JP 2016516072A5 JP 2016503369 A JP2016503369 A JP 2016503369A JP 2016503369 A JP2016503369 A JP 2016503369A JP 2016516072 A5 JP2016516072 A5 JP 2016516072A5
- Authority
- JP
- Japan
- Prior art keywords
- contrast medium
- formulation
- enteric
- intestinal
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002872 contrast media Substances 0.000 claims 27
- 238000009472 formulation Methods 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 12
- 230000000968 intestinal effect Effects 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 239000011248 coating agent Substances 0.000 claims 5
- 238000000576 coating method Methods 0.000 claims 5
- 238000011177 media preparation Methods 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- 239000000463 material Substances 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 4
- 229940039231 contrast media Drugs 0.000 claims 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- 235000005985 organic acids Nutrition 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000003981 vehicle Substances 0.000 claims 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229920002873 Polyethylenimine Polymers 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 150000001642 boronic acid derivatives Chemical class 0.000 claims 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000000084 colloidal system Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000018044 dehydration Effects 0.000 claims 1
- 238000006297 dehydration reaction Methods 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 150000004679 hydroxides Chemical class 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 239000011630 iodine Substances 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 229920001542 oligosaccharide Polymers 0.000 claims 1
- 150000002482 oligosaccharides Chemical class 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 239000006179 pH buffering agent Substances 0.000 claims 1
- 235000021317 phosphate Nutrition 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- -1 poly (siloxane) Polymers 0.000 claims 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 1
- 229920001308 poly(aminoacid) Polymers 0.000 claims 1
- 229920000058 polyacrylate Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 210000000664 rectum Anatomy 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000000375 suspending agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- 229920003169 water-soluble polymer Polymers 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790734P | 2013-03-15 | 2013-03-15 | |
| US201361798392P | 2013-03-15 | 2013-03-15 | |
| US61/798,392 | 2013-03-15 | ||
| US61/790,734 | 2013-03-15 | ||
| PCT/US2014/030295 WO2014145509A1 (en) | 2013-03-15 | 2014-03-17 | Enteric ct contrast material based on low-z atoms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018038401A Division JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低ｚ原子による腸管ｃｔ造影材料 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016516072A JP2016516072A (ja) | 2016-06-02 |
| JP2016516072A5 true JP2016516072A5 (https=) | 2017-04-20 |
Family
ID=51530440
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016503369A Pending JP2016516072A (ja) | 2013-03-15 | 2014-03-17 | 低ｚ原子による腸管ｃｔ造影材料 |
| JP2018038401A Active JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低ｚ原子による腸管ｃｔ造影材料 |
| JP2020144080A Pending JP2020193223A (ja) | 2013-03-15 | 2020-08-28 | 低ｚ原子による腸管ｃｔ造影材料 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018038401A Active JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低ｚ原子による腸管ｃｔ造影材料 |
| JP2020144080A Pending JP2020193223A (ja) | 2013-03-15 | 2020-08-28 | 低ｚ原子による腸管ｃｔ造影材料 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11033640B2 (https=) |
| EP (2) | EP2968619B1 (https=) |
| JP (3) | JP2016516072A (https=) |
| CN (2) | CN105142680A (https=) |
| ES (1) | ES2897624T3 (https=) |
| WO (1) | WO2014145509A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2968619B1 (en) | 2013-03-15 | 2021-08-11 | The Regents of the University of California | Enteric ct contrast material based on low-z atoms |
| JP2016528259A (ja) | 2013-08-16 | 2016-09-15 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | シリコーン系腸管ｃｔ造影材料 |
| WO2016172256A1 (en) | 2015-04-20 | 2016-10-27 | The Regents Of The University Of California | Encapsulated gas or partial vacuum ct contrast material |
| US20200179539A1 (en) * | 2016-06-22 | 2020-06-11 | Board Of Regents, The University Of Texas System | Contrast Agents and Methods of Making the Same for Spectral CT That Exhibit Cloaking and Auto-Segmentation |
| AU2017371069C1 (en) | 2016-12-08 | 2025-02-27 | Centre National De La Recherche Scientifique | Bismuth-gadolinium nanoparticles |
| CN109100775B (zh) * | 2018-07-06 | 2020-05-29 | 郑州云海信息技术有限公司 | 一种双层探测器的能量谱校正方法与装置 |
| JP2020103571A (ja) * | 2018-12-27 | 2020-07-09 | キヤノンメディカルシステムズ株式会社 | 医用処理装置及びｘ線診断システム |
| US20220401587A1 (en) * | 2021-05-05 | 2022-12-22 | The Regents Of The University Of California | Low x-ray attenuation change hard shelled oral contrast material |
| WO2024086131A1 (en) * | 2022-10-18 | 2024-04-25 | The Johns Hopkins University | Systems and methods for angiography using multi-energy detectors |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592185A (en) * | 1967-04-18 | 1971-07-13 | Yeda Res & Dev | Ferromagnetic contrast media and method of use |
| US4615879A (en) * | 1983-11-14 | 1986-10-07 | Vanderbilt University | Particulate NMR contrast agents for gastrointestinal application |
| JPS6238172A (ja) | 1985-08-12 | 1987-02-19 | 株式会社 高研 | 抗血栓性医用材料の製造方法 |
| DE3709851A1 (de) * | 1987-03-24 | 1988-10-06 | Silica Gel Gmbh Adsorptions Te | Nmr-diagnostische fluessigkeitszusammensetzungen |
| IL82834A (en) | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
| GB9006671D0 (en) | 1990-03-24 | 1990-05-23 | Univ Manchester | Diagnostic method and compositions |
| US5205290A (en) | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
| SE9101709L (sv) * | 1991-06-03 | 1992-12-04 | Karlshamns Lipidteknik Ab | Lipidderivat som diagnostikum eller kontrastmedel |
| US5323780A (en) * | 1992-08-07 | 1994-06-28 | University Of Florida Research Foundation, Inc. | Artifact-free imaging contrast agent |
| US5472682A (en) | 1993-03-31 | 1995-12-05 | Sterling Winthrop Inc. | Compositions of iodophenyl esters and iodophenyl sulfonates and pharmaceutically acceptable clays for visualization of the gastrointestinal tract |
| US5318769A (en) | 1993-03-31 | 1994-06-07 | Sterling Winthrop Inc. | Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract |
| FI963299A7 (fi) | 1994-02-25 | 1996-08-23 | Nycomed Imaging As | Röntgenvarjoainekoostumukset, jotka sisältävät selluloosajohdannaisia |
| EP0756497A1 (en) | 1994-04-21 | 1997-02-05 | Nycomed Imaging As | X-ray contrast compositions containing pharmaceutically acceptable clays |
| US5736121A (en) | 1994-05-23 | 1998-04-07 | Imarx Pharmaceutical Corp. | Stabilized homogenous suspensions as computed tomography contrast agents |
| US6818199B1 (en) * | 1994-07-29 | 2004-11-16 | James F. Hainfeld | Media and methods for enhanced medical imaging |
| US5580579A (en) * | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
| GB9603547D0 (en) | 1996-02-20 | 1996-04-17 | Nycomed Imaging As | Contrast media |
| CN1221250C (zh) * | 1998-04-09 | 2005-10-05 | 阿莫萨姆保健公司 | 微粒造影剂在研究生理参数的诊断成像中的应用 |
| NO20052429D0 (no) * | 2005-05-20 | 2005-05-20 | Amersham Health As | Konstrastmidler |
| GB0519391D0 (en) | 2005-09-22 | 2005-11-02 | Aion Diagnostics Ltd | Imaging agents |
| US20070258907A1 (en) * | 2006-04-24 | 2007-11-08 | Davis Mark E | Polymer-coated paramagnetic particles |
| EP2127682A1 (en) * | 2008-05-28 | 2009-12-02 | Deutsches Krebsforschungszentrum | X-ray contrast agent based on bismuth oxide-nanoparticles |
| US20130266590A1 (en) | 2010-12-13 | 2013-10-10 | Novartis Ag | Dimeric iap inhibitors |
| CA2819795A1 (en) | 2010-12-15 | 2012-06-21 | General Electric Company | Nanoparticle composition and associated methods thereof |
| SG192181A1 (en) * | 2011-01-28 | 2013-08-30 | Univ Dalhousie | Radiopaque embolic particles |
| US10071174B2 (en) | 2011-06-06 | 2018-09-11 | Portland State University | Bismuth particle X-ray contrast agents |
| WO2013184061A1 (en) * | 2012-06-04 | 2013-12-12 | Migrata U.K. Limited | Medical use of particles of titanium and/or titanium oxide |
| EP2968619B1 (en) | 2013-03-15 | 2021-08-11 | The Regents of the University of California | Enteric ct contrast material based on low-z atoms |
| JP2016528259A (ja) * | 2013-08-16 | 2016-09-15 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | シリコーン系腸管ｃｔ造影材料 |
-
2014
- 2014-03-17 EP EP14764088.2A patent/EP2968619B1/en active Active
- 2014-03-17 US US14/215,827 patent/US11033640B2/en active Active
- 2014-03-17 WO PCT/US2014/030295 patent/WO2014145509A1/en not_active Ceased
- 2014-03-17 EP EP21190284.6A patent/EP3984560A1/en active Pending
- 2014-03-17 JP JP2016503369A patent/JP2016516072A/ja active Pending
- 2014-03-17 ES ES14764088T patent/ES2897624T3/es active Active
- 2014-03-17 CN CN201480022822.8A patent/CN105142680A/zh active Pending
- 2014-03-17 CN CN201810611475.2A patent/CN108743976B/zh active Active
-
2018
- 2018-03-05 JP JP2018038401A patent/JP6843787B2/ja active Active
-
2020
- 2020-08-28 JP JP2020144080A patent/JP2020193223A/ja active Pending
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