CN105142680A - 基于低-z原子的肠ct造影材料 - Google Patents

基于低-z原子的肠ct造影材料 Download PDF

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Publication number
CN105142680A
CN105142680A CN201480022822.8A CN201480022822A CN105142680A CN 105142680 A CN105142680 A CN 105142680A CN 201480022822 A CN201480022822 A CN 201480022822A CN 105142680 A CN105142680 A CN 105142680A
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CN
China
Prior art keywords
contrast
formulation
enterographic
contrast material
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480022822.8A
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English (en)
Chinese (zh)
Inventor
B·M·耶
付雁军
T·德塞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Priority to CN201810611475.2A priority Critical patent/CN108743976B/zh
Publication of CN105142680A publication Critical patent/CN105142680A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/481—Diagnostic techniques involving the use of contrast agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
CN201480022822.8A 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料 Pending CN105142680A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810611475.2A CN108743976B (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361790734P 2013-03-15 2013-03-15
US201361798392P 2013-03-15 2013-03-15
US61/798,392 2013-03-15
US61/790,734 2013-03-15
PCT/US2014/030295 WO2014145509A1 (en) 2013-03-15 2014-03-17 Enteric ct contrast material based on low-z atoms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201810611475.2A Division CN108743976B (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

Publications (1)

Publication Number Publication Date
CN105142680A true CN105142680A (zh) 2015-12-09

Family

ID=51530440

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480022822.8A Pending CN105142680A (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料
CN201810611475.2A Active CN108743976B (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201810611475.2A Active CN108743976B (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

Country Status (6)

Country Link
US (1) US11033640B2 (https=)
EP (2) EP2968619B1 (https=)
JP (3) JP2016516072A (https=)
CN (2) CN105142680A (https=)
ES (1) ES2897624T3 (https=)
WO (1) WO2014145509A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109100775A (zh) * 2018-07-06 2018-12-28 郑州云海信息技术有限公司 一种双层探测器的能量谱校正方法与装置

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2968619B1 (en) 2013-03-15 2021-08-11 The Regents of the University of California Enteric ct contrast material based on low-z atoms
JP2016528259A (ja) 2013-08-16 2016-09-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア シリコーン系腸管ｃｔ造影材料
WO2016172256A1 (en) 2015-04-20 2016-10-27 The Regents Of The University Of California Encapsulated gas or partial vacuum ct contrast material
US20200179539A1 (en) * 2016-06-22 2020-06-11 Board Of Regents, The University Of Texas System Contrast Agents and Methods of Making the Same for Spectral CT That Exhibit Cloaking and Auto-Segmentation
AU2017371069C1 (en) 2016-12-08 2025-02-27 Centre National De La Recherche Scientifique Bismuth-gadolinium nanoparticles
JP2020103571A (ja) * 2018-12-27 2020-07-09 キヤノンメディカルシステムズ株式会社 医用処理装置及びｘ線診断システム
US20220401587A1 (en) * 2021-05-05 2022-12-22 The Regents Of The University Of California Low x-ray attenuation change hard shelled oral contrast material
WO2024086131A1 (en) * 2022-10-18 2024-04-25 The Johns Hopkins University Systems and methods for angiography using multi-energy detectors

Citations (3)

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Publication number Priority date Publication date Assignee Title
US3592185A (en) * 1967-04-18 1971-07-13 Yeda Res & Dev Ferromagnetic contrast media and method of use
WO1992017514A1 (en) * 1991-04-05 1992-10-15 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
WO1994003107A1 (en) * 1992-08-07 1994-02-17 University Of Florida Artifact-free imaging contrast agent

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US4615879A (en) * 1983-11-14 1986-10-07 Vanderbilt University Particulate NMR contrast agents for gastrointestinal application
JPS6238172A (ja) 1985-08-12 1987-02-19 株式会社　高研 抗血栓性医用材料の製造方法
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
GB9006671D0 (en) 1990-03-24 1990-05-23 Univ Manchester Diagnostic method and compositions
SE9101709L (sv) * 1991-06-03 1992-12-04 Karlshamns Lipidteknik Ab Lipidderivat som diagnostikum eller kontrastmedel
US5472682A (en) 1993-03-31 1995-12-05 Sterling Winthrop Inc. Compositions of iodophenyl esters and iodophenyl sulfonates and pharmaceutically acceptable clays for visualization of the gastrointestinal tract
US5318769A (en) 1993-03-31 1994-06-07 Sterling Winthrop Inc. Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract
FI963299A7 (fi) 1994-02-25 1996-08-23 Nycomed Imaging As Röntgenvarjoainekoostumukset, jotka sisältävät selluloosajohdannaisia
EP0756497A1 (en) 1994-04-21 1997-02-05 Nycomed Imaging As X-ray contrast compositions containing pharmaceutically acceptable clays
US5736121A (en) 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
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US5580579A (en) * 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
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CN1221250C (zh) * 1998-04-09 2005-10-05 阿莫萨姆保健公司 微粒造影剂在研究生理参数的诊断成像中的应用
NO20052429D0 (no) * 2005-05-20 2005-05-20 Amersham Health As Konstrastmidler
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JP2016528259A (ja) * 2013-08-16 2016-09-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア シリコーン系腸管ｃｔ造影材料

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592185A (en) * 1967-04-18 1971-07-13 Yeda Res & Dev Ferromagnetic contrast media and method of use
WO1992017514A1 (en) * 1991-04-05 1992-10-15 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
WO1994003107A1 (en) * 1992-08-07 1994-02-17 University Of Florida Artifact-free imaging contrast agent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
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L. F. GAMARRA ET AL.: "Characterization of Superparamagnetic Iron Oxide Coated with Silicone Used as Contrast Agent for Magnetic Resonance Image for the Gastrointestinal Tract", 《J. NANOSCI. NANOTECHNOL.》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109100775A (zh) * 2018-07-06 2018-12-28 郑州云海信息技术有限公司 一种双层探测器的能量谱校正方法与装置

Also Published As

Publication number Publication date
CN108743976B (zh) 2021-10-29
JP6843787B2 (ja) 2021-03-17
WO2014145509A1 (en) 2014-09-18
EP3984560A1 (en) 2022-04-20
JP2018090624A (ja) 2018-06-14
EP2968619B1 (en) 2021-08-11
ES2897624T3 (es) 2022-03-02
JP2020193223A (ja) 2020-12-03
US20140276021A1 (en) 2014-09-18
EP2968619A1 (en) 2016-01-20
EP2968619A4 (en) 2016-11-02
JP2016516072A (ja) 2016-06-02
CN108743976A (zh) 2018-11-06
US11033640B2 (en) 2021-06-15

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Application publication date: 20151209