JP2016515555A5 - - Google Patents

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Publication number
JP2016515555A5
JP2016515555A5 JP2016504606A JP2016504606A JP2016515555A5 JP 2016515555 A5 JP2016515555 A5 JP 2016515555A5 JP 2016504606 A JP2016504606 A JP 2016504606A JP 2016504606 A JP2016504606 A JP 2016504606A JP 2016515555 A5 JP2016515555 A5 JP 2016515555A5
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JP
Japan
Prior art keywords
acid
formula
compound
reacting
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016504606A
Other languages
English (en)
Japanese (ja)
Other versions
JP6400672B2 (ja
JP2016515555A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2014/055815 external-priority patent/WO2014154620A1/en
Publication of JP2016515555A publication Critical patent/JP2016515555A/ja
Publication of JP2016515555A5 publication Critical patent/JP2016515555A5/ja
Application granted granted Critical
Publication of JP6400672B2 publication Critical patent/JP6400672B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016504606A 2013-03-25 2014-03-24 アルカフタジンの製造方法 Active JP6400672B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13160829 2013-03-25
EP13160829.1 2013-03-25
PCT/EP2014/055815 WO2014154620A1 (en) 2013-03-25 2014-03-24 Methods for the preparation of alcaftadine

Publications (3)

Publication Number Publication Date
JP2016515555A JP2016515555A (ja) 2016-05-30
JP2016515555A5 true JP2016515555A5 (enExample) 2017-03-30
JP6400672B2 JP6400672B2 (ja) 2018-10-03

Family

ID=47913271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016504606A Active JP6400672B2 (ja) 2013-03-25 2014-03-24 アルカフタジンの製造方法

Country Status (7)

Country Link
US (1) US9682984B2 (enExample)
EP (1) EP2978765B1 (enExample)
JP (1) JP6400672B2 (enExample)
KR (1) KR102204578B1 (enExample)
CA (1) CA2907396C (enExample)
ES (1) ES2680933T3 (enExample)
WO (1) WO2014154620A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104860920B (zh) * 2015-04-15 2017-08-25 武汉武药科技有限公司 一种阿卡他定中间体的制备方法
CN104987337B (zh) * 2015-07-28 2018-01-12 武汉武药科技有限公司 一种制备阿卡他定的氧化方法
WO2018126229A2 (en) 2016-12-30 2018-07-05 Sutrovax, Inc. Polypeptide-antigen conjugates with non-natural amino acids
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070381A (en) * 1972-07-12 1978-01-24 Lever Brothers Company Certain 2-(hydroxyalkyl)-2,5-dialkyl-4-hydroxy-4,5-dihydrofuran-3-ones and method for their preparation
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv 11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
US20080139531A1 (en) 2006-12-04 2008-06-12 Alcon Manufacturing Ltd. Use of connective tissue mast cell stabilizers to facilitate ocular surface re-epithelization and wound repair
WO2014083571A1 (en) 2012-11-29 2014-06-05 Neuland Laboratories Limited A process for the preparation of alcaftadine

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