JP2016514248A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016514248A5 JP2016514248A5 JP2015557203A JP2015557203A JP2016514248A5 JP 2016514248 A5 JP2016514248 A5 JP 2016514248A5 JP 2015557203 A JP2015557203 A JP 2015557203A JP 2015557203 A JP2015557203 A JP 2015557203A JP 2016514248 A5 JP2016514248 A5 JP 2016514248A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- low
- kit
- risk classification
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 claims description 88
- 201000011510 cancer Diseases 0.000 claims description 34
- 210000004027 cell Anatomy 0.000 claims description 17
- 101100422204 Candida albicans (strain SC5314 / ATCC MYA-2876) CDC68 gene Proteins 0.000 claims description 16
- 101100422210 Drosophila melanogaster dre4 gene Proteins 0.000 claims description 16
- 102100028166 FACT complex subunit SSRP1 Human genes 0.000 claims description 16
- 101000697353 Homo sapiens FACT complex subunit SSRP1 Proteins 0.000 claims description 16
- 101100043306 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) ctc-2 gene Proteins 0.000 claims description 16
- 101150097243 SPT16 gene Proteins 0.000 claims description 16
- 230000008901 benefit Effects 0.000 claims description 16
- 230000036210 malignancy Effects 0.000 claims description 16
- 238000005259 measurement Methods 0.000 claims description 9
- 108010077544 Chromatin Proteins 0.000 claims description 8
- 206010027476 Metastases Diseases 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 210000003483 chromatin Anatomy 0.000 claims description 8
- 230000009401 metastasis Effects 0.000 claims description 8
- 238000011227 neoadjuvant chemotherapy Methods 0.000 claims description 8
- 230000004083 survival effect Effects 0.000 claims description 8
- 210000001519 tissue Anatomy 0.000 claims description 8
- 238000011226 adjuvant chemotherapy Methods 0.000 claims description 7
- 238000009098 adjuvant therapy Methods 0.000 claims description 6
- 238000009099 neoadjuvant therapy Methods 0.000 claims description 6
- 238000003745 diagnosis Methods 0.000 claims description 5
- 238000004393 prognosis Methods 0.000 claims description 5
- 238000013518 transcription Methods 0.000 claims description 5
- 230000035897 transcription Effects 0.000 claims description 5
- 210000004881 tumor cell Anatomy 0.000 claims description 5
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 claims description 4
- 238000002965 ELISA Methods 0.000 claims description 4
- 238000001574 biopsy Methods 0.000 claims description 4
- 210000000481 breast Anatomy 0.000 claims description 4
- 210000003169 central nervous system Anatomy 0.000 claims description 4
- 210000003679 cervix uteri Anatomy 0.000 claims description 4
- 210000003128 head Anatomy 0.000 claims description 4
- 238000003125 immunofluorescent labeling Methods 0.000 claims description 4
- 238000011532 immunohistochemical staining Methods 0.000 claims description 4
- 210000003734 kidney Anatomy 0.000 claims description 4
- 210000004185 liver Anatomy 0.000 claims description 4
- 210000004072 lung Anatomy 0.000 claims description 4
- 210000003739 neck Anatomy 0.000 claims description 4
- 210000001672 ovary Anatomy 0.000 claims description 4
- 210000000496 pancreas Anatomy 0.000 claims description 4
- 210000001428 peripheral nervous system Anatomy 0.000 claims description 4
- 210000002307 prostate Anatomy 0.000 claims description 4
- 102000004169 proteins and genes Human genes 0.000 claims description 4
- 108090000623 proteins and genes Proteins 0.000 claims description 4
- 230000000306 recurrent effect Effects 0.000 claims description 4
- 230000009467 reduction Effects 0.000 claims description 4
- 210000003491 skin Anatomy 0.000 claims description 4
- 210000000130 stem cell Anatomy 0.000 claims description 4
- 210000003932 urinary bladder Anatomy 0.000 claims description 4
- 238000001262 western blot Methods 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- 210000004748 cultured cell Anatomy 0.000 claims description 3
- 238000011156 evaluation Methods 0.000 claims description 3
- 239000002246 antineoplastic agent Substances 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 229940124597 therapeutic agent Drugs 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000001943 fluorescence-activated cell sorting Methods 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 39
- 108091023040 Transcription factor Proteins 0.000 description 3
- 102000040945 Transcription factor Human genes 0.000 description 3
- 239000000463 material Substances 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361763266P | 2013-02-11 | 2013-02-11 | |
| US61/763,266 | 2013-02-11 | ||
| US201361883802P | 2013-09-27 | 2013-09-27 | |
| US61/883,802 | 2013-09-27 | ||
| PCT/US2014/015854 WO2014124454A1 (en) | 2013-02-11 | 2014-02-11 | Use of facilitates chromatin transcription complex (fact) in cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016514248A JP2016514248A (ja) | 2016-05-19 |
| JP2016514248A5 true JP2016514248A5 (enExample) | 2017-03-16 |
| JP6576249B2 JP6576249B2 (ja) | 2019-09-18 |
Family
ID=51300203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015557203A Expired - Fee Related JP6576249B2 (ja) | 2013-02-11 | 2014-02-11 | 癌におけるクロマチン転写促進因子（ｆａｃｔ）の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10386370B2 (enExample) |
| EP (1) | EP2954331B1 (enExample) |
| JP (1) | JP6576249B2 (enExample) |
| CN (1) | CN104981697B (enExample) |
| EA (1) | EA036615B1 (enExample) |
| WO (1) | WO2014124454A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108333366B (zh) * | 2018-01-26 | 2020-06-12 | 南通大学附属医院 | 一种实验性监测肝细胞恶性转化过程大鼠模型的建立方法 |
| CN109136376B (zh) * | 2018-05-21 | 2021-09-21 | 中国医科大学附属第四医院 | 一种膀胱癌相关环状RNA的应用和siRNA及其用途 |
| CN113721020B (zh) * | 2021-09-14 | 2022-06-24 | 大连医科大学附属第二医院 | Ctsf在非小细胞肺癌诊断中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2715680A1 (de) | 1977-04-07 | 1978-10-12 | Henkel Kgaa | Haarfaerbemittel |
| EP2261368A1 (en) | 2002-03-13 | 2010-12-15 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| WO2004035580A1 (en) | 2002-10-21 | 2004-04-29 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| WO2005039382A2 (en) | 2003-06-24 | 2005-05-06 | Genomic Health | Prediction of likelihood of cancer recurrence |
| EP1644858B1 (en) | 2003-07-10 | 2017-12-06 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| US7169802B2 (en) | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US20100047783A1 (en) | 2006-06-20 | 2010-02-25 | El-Diery Wafik S | Small molecule modulators of p53 family signaling |
| WO2009055823A2 (en) * | 2007-10-26 | 2009-04-30 | Progen Pharmaceuticals Limited | Method to predict responsiveness of breast cancer to polyaminetype chemotherapy |
| AU2009246009A1 (en) | 2008-05-14 | 2009-11-19 | University Health Network | Prognostic and predictive gene signature for non-small cell lung cancer and adjuvant chemotherapy |
| GEP20156300B (en) | 2008-05-20 | 2015-06-25 | Incuron Llc | Inducing cell death by inhibiting adaptive heat shock response |
| US20100081666A1 (en) | 2008-07-14 | 2010-04-01 | Wyeth | Src activation for determining cancer prognosis and as a target for cancer therapy |
| UA107652C2 (en) | 2008-10-06 | 2015-02-10 | Incuron Llc | Carbazole compounds and therapeutic uses of the compounds |
| US20100331210A1 (en) | 2009-05-29 | 2010-12-30 | Precision Therapeutics, Inc. | Methods and systems for evaluating the sensitivity or resistance of tumor specimens to chemotherapeutic agents |
| EA028630B1 (ru) | 2012-03-27 | 2017-12-29 | ИНКУРОН ЭлЭлСи | Способ предотвращения вызванного канцерогеном рака с применением кураксина-137 |
| US20140066465A1 (en) | 2012-09-04 | 2014-03-06 | The Cleveland Clinic Foundation | CANCER TREATMENT USING TYROSINE KINASE AND NF-kB INHIBITORS |
-
2014
- 2014-02-11 CN CN201480008187.8A patent/CN104981697B/zh not_active Expired - Fee Related
- 2014-02-11 US US14/766,693 patent/US10386370B2/en active Active
- 2014-02-11 JP JP2015557203A patent/JP6576249B2/ja not_active Expired - Fee Related
- 2014-02-11 EP EP14748917.3A patent/EP2954331B1/en not_active Not-in-force
- 2014-02-11 WO PCT/US2014/015854 patent/WO2014124454A1/en not_active Ceased
- 2014-02-11 EA EA201591304A patent/EA036615B1/ru not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Graziano et al. | Combination of peripheral neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio is predictive of pathological complete response after neoadjuvant chemotherapy in breast cancer patients | |
| Maly et al. | Circulating tumor cells in diagnosis and treatment of lung cancer | |
| Ogle et al. | Imagestream detection and characterisation of circulating tumour cells–a liquid biopsy for hepatocellular carcinoma? | |
| Alamgeer et al. | The prognostic significance of aldehyde dehydrogenase 1A1 (ALDH1A1) and CD133 expression in early stage non-small cell lung cancer | |
| Kondalsamy-Chennakesavan et al. | Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age | |
| Espinosa-Bravo et al. | Prediction of non-sentinel lymph node metastasis in early breast cancer by assessing total tumoral load in the sentinel lymph node by molecular assay | |
| Ding et al. | Expression characteristics of CDC20 in gastric cancer and its correlation with poor prognosis | |
| Ma et al. | Prognostic role of circulating tumor cells and disseminated tumor cells in patients with prostate cancer: a systematic review and meta-analysis | |
| Lee et al. | Circulating tumor cells in breast cancer: applications in personalized medicine | |
| Sonnenblick et al. | Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis | |
| Usó et al. | Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers | |
| Ruiz et al. | Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients | |
| Song et al. | Prognostic value of HMGB3 expression in patients with non-small cell lung cancer | |
| Hu et al. | The upregulation of trophinin-associated protein (TROAP) predicts a poor prognosis in hepatocellular carcinoma | |
| JP2012524278A (ja) | がんの臨床診断および予後診断のためのヒストン修飾パターン | |
| Szarvas et al. | High insulin‐like growth factor mRNA‐binding protein 3 (IMP3) protein expression is associated with poor survival in muscle‐invasive bladder cancer | |
| Hokka et al. | Psf3 is a prognostic biomarker in lung adenocarcinoma | |
| Fan et al. | Immunostaining with EGFR mutation–specific antibodies: a reliable screening method for lung adenocarcinomas harboring EGFR mutation in biopsy and resection samples | |
| US10267802B2 (en) | Methods of prognosis and diagnosis of ovarian cancer | |
| Zhang et al. | ANCCA protein expression is a novel independent poor prognostic marker in surgically resected lung adenocarcinoma | |
| Augustin et al. | Receptor for hyaluronic acid-mediated motility (RHAMM, CD168) expression is prognostically important in both nodal negative and nodal positive large cell lung cancer | |
| Vasilevska et al. | Cytokeratin Expression Pattern in Human Endometrial Carcinomas and Lymph Nodes Micrometastasis: a Mini-review | |
| Franceschini et al. | Mesothelin in serum and pleural effusion in the diagnosis of malignant pleural mesothelioma with non-positive cytology | |
| Luo et al. | Prognostic relevance of Id-1 expression in patients with resectable esophageal squamous cell carcinoma | |
| Bode et al. | MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors |