JP2016513730A5 - - Google Patents

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Publication number
JP2016513730A5
JP2016513730A5 JP2016502750A JP2016502750A JP2016513730A5 JP 2016513730 A5 JP2016513730 A5 JP 2016513730A5 JP 2016502750 A JP2016502750 A JP 2016502750A JP 2016502750 A JP2016502750 A JP 2016502750A JP 2016513730 A5 JP2016513730 A5 JP 2016513730A5
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JP
Japan
Prior art keywords
alkyl
haloalkyl
pharmaceutically acceptable
acceptable salt
ring
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JP2016502750A
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English (en)
Japanese (ja)
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JP2016513730A (ja
JP6442475B2 (ja
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Priority claimed from PCT/US2014/028274 external-priority patent/WO2014144037A1/en
Publication of JP2016513730A publication Critical patent/JP2016513730A/ja
Publication of JP2016513730A5 publication Critical patent/JP2016513730A5/ja
Application granted granted Critical
Publication of JP6442475B2 publication Critical patent/JP6442475B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016502750A 2013-03-15 2014-03-14 Ｌｘｒ調節因子 Expired - Fee Related JP6442475B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786974P 2013-03-15 2013-03-15
US61/786,974 2013-03-15
PCT/US2014/028274 WO2014144037A1 (en) 2013-03-15 2014-03-14 Lxr modulators

Publications (3)

Publication Number Publication Date
JP2016513730A JP2016513730A (ja) 2016-05-16
JP2016513730A5 true JP2016513730A5 (https=) 2017-04-20
JP6442475B2 JP6442475B2 (ja) 2018-12-19

Family

ID=51537598

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016502750A Expired - Fee Related JP6442475B2 (ja) 2013-03-15 2014-03-14 Ｌｘｒ調節因子

Country Status (5)

Country Link
US (1) US9834542B2 (https=)
EP (1) EP2968275B1 (https=)
JP (1) JP6442475B2 (https=)
CN (1) CN105209039B (https=)
WO (1) WO2014144037A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6456909B2 (ja) 2013-03-15 2019-01-23 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｌｘｒ調節因子
WO2015106164A1 (en) 2014-01-10 2015-07-16 Rgenix, Inc. Lxr agonists and uses thereof
CN104817525B (zh) * 2015-04-13 2017-11-17 江苏大学 含氟2,3‑二氢苯并呋喃‑3‑醇类化合物及制备方法
EP3402477A4 (en) 2016-01-11 2019-08-21 The Rockefeller University METHOD FOR THE TREATMENT OF DISEASES RELATED TO MYELOID-DERIVED SUPPRESSOR CELLS
CA3078981A1 (en) 2017-11-21 2019-05-31 Rgenix, Inc. Polymorphs and uses thereof
CN109867645B (zh) * 2017-12-05 2021-09-14 中国医学科学院药物研究所 一种2,2-二氟-2,3-二氢取代苯并呋喃类化合物的合成方法
TWI748194B (zh) * 2018-06-28 2021-12-01 德商菲尼克斯 Ｆｘｒ有限責任公司 含有雙環核心部分之新穎lxr調節劑
CN113474335B (zh) * 2019-02-21 2024-12-03 南京瑞捷医药科技有限公司 化合物及其作为甲状腺激素受体激动剂的用途
CN110330493B (zh) * 2019-08-23 2020-07-24 广州麓鹏制药有限公司 Pim激酶抑制剂、其制备方法、应用、药物及药物组合
TWI888447B (zh) 2019-12-13 2025-07-01 美商因思博納公司 金屬鹽及其用途

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