JP2016511747A5 - - Google Patents
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- Publication number
- JP2016511747A5 JP2016511747A5 JP2015551772A JP2015551772A JP2016511747A5 JP 2016511747 A5 JP2016511747 A5 JP 2016511747A5 JP 2015551772 A JP2015551772 A JP 2015551772A JP 2015551772 A JP2015551772 A JP 2015551772A JP 2016511747 A5 JP2016511747 A5 JP 2016511747A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- peptide
- connective tissue
- polymer
- active agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002105 nanoparticle Substances 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 239000013543 active substance Substances 0.000 claims 8
- 210000002808 connective tissue Anatomy 0.000 claims 8
- 239000011859 microparticle Substances 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 8
- 239000002245 particle Substances 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 5
- 229940124597 therapeutic agent Drugs 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 108090001008 Avidin Proteins 0.000 claims 3
- 208000023178 Musculoskeletal disease Diseases 0.000 claims 2
- 206010073713 Musculoskeletal injury Diseases 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 208000020084 Bone disease Diseases 0.000 claims 1
- 230000003160 anti-catabolic effect Effects 0.000 claims 1
- 229940124346 antiarthritic agent Drugs 0.000 claims 1
- 239000003435 antirheumatic agent Substances 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000018631 connective tissue disease Diseases 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 208000017445 musculoskeletal system disease Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361748809P | 2013-01-04 | 2013-01-04 | |
| US61/748,809 | 2013-01-04 | ||
| US201361870288P | 2013-08-27 | 2013-08-27 | |
| US61/870,288 | 2013-08-27 | ||
| PCT/US2014/010162 WO2014107566A1 (en) | 2013-01-04 | 2014-01-03 | Surface binding of nanoparticle based drug delivery to tissue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016511747A JP2016511747A (ja) | 2016-04-21 |
| JP2016511747A5 true JP2016511747A5 (https=) | 2017-06-29 |
Family
ID=51061134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551772A Pending JP2016511747A (ja) | 2013-01-04 | 2014-01-03 | ナノ粒子表面結合に基づく薬物の組織への送達 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9289506B2 (https=) |
| EP (1) | EP2941243A4 (https=) |
| JP (1) | JP2016511747A (https=) |
| WO (1) | WO2014107566A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013008697A2 (pt) | 2010-09-24 | 2016-06-21 | Massachusetts Inst Technology | géis nanoestruturados capazes de liberação controlada de agentes encapsulados |
| GB201412610D0 (en) * | 2014-07-16 | 2014-08-27 | Univ Cardiff | Cartilage agent delivery |
| JP6851987B2 (ja) | 2015-12-25 | 2021-03-31 | コニカミノルタ株式会社 | ゼラチン粒子、ゼラチン粒子の製造方法、ゼラチン粒子内包細胞、およびゼラチン粒子内包細胞の製造方法 |
| US10188749B2 (en) | 2016-04-14 | 2019-01-29 | Fred Hutchinson Cancer Research Center | Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers |
| US10583199B2 (en) * | 2016-04-26 | 2020-03-10 | Northwestern University | Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs |
| EP3452094B1 (en) * | 2016-05-06 | 2021-11-17 | The Brigham and Women's Hospital, Inc. | Binary self assembled gels for controlled delivery of encapsulated agents to cartilage |
| CN110121336A (zh) | 2017-01-05 | 2019-08-13 | 弗莱德哈钦森癌症研究中心 | 改善疫苗功效的系统和方法 |
| KR20250099256A (ko) | 2018-01-18 | 2025-07-01 | 프레드 허친슨 캔서 센터 | 세포 활성화 상태를 조절함으로써 생체내 면역 세포의 염증 상태의 변경 |
| CN108531616B (zh) * | 2018-04-28 | 2021-08-10 | 中国农业科学院兰州畜牧与兽药研究所 | 一种牦牛体格相关的基因分子标记、检测方法和试剂盒 |
| CA3113948A1 (en) | 2018-10-11 | 2020-04-16 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
| WO2021021276A1 (en) * | 2019-07-26 | 2021-02-04 | Massachusetts Institute Of Technology | Multi-targeted, tunable, sustained delivery of payloads to charged avascular tissues |
| US20210154307A1 (en) * | 2019-11-07 | 2021-05-27 | Northeastern University | Cationic nanostructures for intra-cartilage delivery of therapeutics and contrast agents |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991003553A1 (en) * | 1989-09-05 | 1991-03-21 | Immunex Corporation | TUMOR NECROSIS FACTOR-α AND -β RECEPTORS |
| US8795242B2 (en) | 1994-05-13 | 2014-08-05 | Kensey Nash Corporation | Resorbable polymeric device for localized drug delivery |
| US5723125A (en) | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
| US6958148B1 (en) | 1998-01-20 | 2005-10-25 | Pericor Science, Inc. | Linkage of agents to body tissue using microparticles and transglutaminase |
| US20060084794A1 (en) * | 2001-04-12 | 2006-04-20 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| ITRM20020128A1 (it) | 2002-03-08 | 2003-09-08 | Sigma Tau Ind Farmaceuti | Dimeri di avidina efficaci nell'incrementare la concentrazione di biotina radioattiva nella immunoterapia con "pretargeting". |
| KR101317045B1 (ko) * | 2002-09-06 | 2013-10-16 | 암젠 인코포레이티드 | 치료학적 인체 항-ｉｌ-1ｒ1 모노클로날 항체 |
| GB0313569D0 (en) * | 2003-06-12 | 2003-07-16 | Plasso Technology Ltd | Method |
| EP1715971A4 (en) * | 2004-01-28 | 2010-10-13 | Cytimmune Sciences Inc | FUNCTIONALIZED COLLOIDAL METAL COMPOSITIONS AND METHODS |
| WO2005107818A2 (en) | 2004-04-30 | 2005-11-17 | University Of Florida | Nanoparticles and their use for multifunctional bioimaging |
| US20090324678A1 (en) | 2004-07-16 | 2009-12-31 | Spinal Restoration, Inc. | Methods and kits for treating joints and soft tissues |
| JP2006247155A (ja) | 2005-03-11 | 2006-09-21 | Aruze Corp | タイピングゲーム装置及びデータベースシステム |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| US20100015068A1 (en) | 2006-07-06 | 2010-01-21 | Massachusetts Institute Of Technology | Methods and Compositions For Altering Biological Surfaces |
| US7592009B2 (en) | 2006-10-10 | 2009-09-22 | Ecole Polytechnique Federale De Lausanne (Epfl) | Polypeptide ligands for targeting cartilage and methods of use thereof |
| TW201531484A (zh) * | 2007-05-21 | 2015-08-16 | Alder Biopharmaceuticals Inc | 抗ＴＮＦ-α之抗體及其用途 |
| EP2185203B1 (en) | 2007-08-02 | 2017-02-22 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Oxidized avidin with high residency time in the treated tissues |
| US20110104052A1 (en) | 2007-12-03 | 2011-05-05 | The Johns Hopkins University | Methods of synthesis and use of chemospheres |
| JP2009292787A (ja) * | 2008-06-06 | 2009-12-17 | Ab Size:Kk | 軟骨再生促進剤 |
| US9333163B2 (en) | 2008-10-06 | 2016-05-10 | Massachusetts Institute Of Technology | Particles with multiple functionalized surface domains |
| US9198873B2 (en) * | 2010-07-19 | 2015-12-01 | National Cheng Kung University | Functionalized nanoparticle, method for preparing the same and application thereof |
| JP6019118B2 (ja) | 2011-08-02 | 2016-11-02 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 吸入に適した酸化型アビジンの医薬品組成物 |
-
2014
- 2014-01-03 JP JP2015551772A patent/JP2016511747A/ja active Pending
- 2014-01-03 WO PCT/US2014/010162 patent/WO2014107566A1/en not_active Ceased
- 2014-01-03 EP EP14735208.2A patent/EP2941243A4/en not_active Withdrawn
- 2014-01-06 US US14/147,863 patent/US9289506B2/en active Active
-
2016
- 2016-03-16 US US15/071,709 patent/US10226427B2/en active Active