JP2015520161A5 - - Google Patents

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Publication number
JP2015520161A5
JP2015520161A5 JP2015512644A JP2015512644A JP2015520161A5 JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5 JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015512644 A JP2015512644 A JP 2015512644A JP 2015520161 A5 JP2015520161 A5 JP 2015520161A5
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JP
Japan
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composition
mammal
nucleic acid
aav
vector
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JP2015512644A
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English (en)
Japanese (ja)
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JP6469000B2 (ja
JP2015520161A (ja
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Priority claimed from PCT/US2013/031725 external-priority patent/WO2013172964A1/en
Publication of JP2015520161A publication Critical patent/JP2015520161A/ja
Publication of JP2015520161A5 publication Critical patent/JP2015520161A5/ja
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Publication of JP6469000B2 publication Critical patent/JP6469000B2/ja
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JP2015512644A 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物 Active JP6469000B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648801P 2012-05-18 2012-05-18
US61/648,801 2012-05-18
PCT/US2013/031725 WO2013172964A1 (en) 2012-05-18 2013-03-14 Methods and compositions for treating amyloid deposits

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018207331A Division JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Publications (3)

Publication Number Publication Date
JP2015520161A JP2015520161A (ja) 2015-07-16
JP2015520161A5 true JP2015520161A5 (https=) 2016-05-12
JP6469000B2 JP6469000B2 (ja) 2019-02-13

Family

ID=49584137

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015512644A Active JP6469000B2 (ja) 2012-05-18 2013-03-14 アミロイドの沈着を処置するための方法および組成物
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018207331A Pending JP2019031564A (ja) 2012-05-18 2018-11-02 アミロイドの沈着を処置するための方法および組成物

Country Status (12)

Country Link
US (1) US20150183850A1 (https=)
EP (1) EP2850195B1 (https=)
JP (2) JP6469000B2 (https=)
CN (2) CN104540952A (https=)
AU (1) AU2013263346B2 (https=)
BR (1) BR112014028666B1 (https=)
CA (1) CA2873890C (https=)
ES (1) ES2786078T3 (https=)
HK (1) HK1207109A1 (https=)
IN (1) IN2014KN02672A (https=)
RU (1) RU2673484C2 (https=)
WO (1) WO2013172964A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230145206A (ko) 2014-11-14 2023-10-17 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
WO2016196507A1 (en) 2015-05-29 2016-12-08 University Of Iowa Research Foundation Methods of delivery of transgenes for treating brain diseases
US20180161395A1 (en) * 2015-06-12 2018-06-14 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical composition for the treatment of alzheimer's disease
CN109072274A (zh) * 2016-04-14 2018-12-21 道健康生活医药株式会社 淀粉样蛋白球体(aspd)样结构体及医药组合物
KR20240056729A (ko) 2016-05-18 2024-04-30 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
AU2017306558B2 (en) * 2016-08-03 2024-09-19 University Of South Florida Reelin compositions for treatment of neurological disorders
JP7610923B2 (ja) * 2016-09-02 2025-01-09 スパーク セラピューティクス インコーポレイテッド Cns障害を治療するための方法及びベクター
EP3309550A1 (en) * 2016-10-12 2018-04-18 sphingotec GmbH Method for the detection of apolipoprotein e4
CN112501208A (zh) 2017-10-03 2021-03-16 普利维尔治疗公司 用于溶酶体障碍的基因疗法
BR112020006661A2 (pt) 2017-10-03 2020-10-13 Prevail Therapeutics, Inc. terapias de genes para distúrbios lipossomais
JP7616995B2 (ja) * 2018-11-28 2025-01-17 プリベイル セラピューティクス,インコーポレーテッド 神経変性疾患のための遺伝子治療
JP2023500793A (ja) * 2019-10-16 2023-01-11 コーネル・ユニバーシティー アルツハイマー病に対する遺伝子治療方法
EP4065600A1 (en) 2019-11-25 2022-10-05 Cornell University Apoe gene therapy
BR112022019864A2 (pt) * 2020-03-31 2022-11-16 Nuo Beta Pharmaceutical Tech Shanghai Co Ltd Composto de oxofenilarsina deuterada e uso do mesmo
KR20230112672A (ko) * 2020-11-25 2023-07-27 프리베일 테라퓨틱스, 인크. 신경변성 질환을 위한 유전자 요법
WO2023108507A1 (en) * 2021-12-15 2023-06-22 National Institute Of Biological Sciences, Beijing Recombinant aav vectors and use thereof
CN116063405B (zh) * 2022-09-27 2025-08-29 广州译码基因科技有限公司 可提高AAV病毒包装能力的衣壳蛋白突变体MutC及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589154A (en) * 1994-11-22 1996-12-31 Rutgers, The State University Of New Jersey Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
US6436996B1 (en) * 1997-09-30 2002-08-20 Duke University Modulation of nitric oxide production
US6468524B1 (en) * 2000-03-22 2002-10-22 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services AAV4 vector and uses thereof
US6855314B1 (en) 2000-03-22 2005-02-15 The United States Of America As Represented By The Department Of Health And Human Services AAV5 vector for transducing brain cells and lung cells
GB0322645D0 (en) * 2003-09-26 2003-10-29 Melacure Therapeutics Ab Use of antisecretory factor peptides
JP5136766B2 (ja) * 2004-12-15 2013-02-06 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル キメラベクター
CA2606490C (en) * 2005-05-02 2018-02-06 Genzyme Corporation Gene therapy for spinal cord disorders
CN102886052B (zh) * 2006-09-14 2014-07-30 迈德詹尼克斯医疗以色列有限公司 长效药物制剂
EP2154969B1 (en) * 2007-05-16 2015-11-18 The Brigham and Women's Hospital, Inc. Treatment of synucleinopathies
EP3444346B1 (en) * 2010-04-23 2022-07-27 University of Massachusetts Aav-based treatment of cholesterol-related disorders

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