JP2016510748A5 - - Google Patents

Download PDF

Info

Publication number
JP2016510748A5
JP2016510748A5 JP2015561618A JP2015561618A JP2016510748A5 JP 2016510748 A5 JP2016510748 A5 JP 2016510748A5 JP 2015561618 A JP2015561618 A JP 2015561618A JP 2015561618 A JP2015561618 A JP 2015561618A JP 2016510748 A5 JP2016510748 A5 JP 2016510748A5
Authority
JP
Japan
Prior art keywords
combination
cancer
alkyl
linear
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015561618A
Other languages
English (en)
Japanese (ja)
Other versions
JP6835472B2 (ja
JP2016510748A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/020858 external-priority patent/WO2014138279A1/en
Publication of JP2016510748A publication Critical patent/JP2016510748A/ja
Publication of JP2016510748A5 publication Critical patent/JP2016510748A5/ja
Application granted granted Critical
Publication of JP6835472B2 publication Critical patent/JP6835472B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015561618A 2013-03-05 2014-03-05 癌の処置のための組成物 Expired - Fee Related JP6835472B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361772885P 2013-03-05 2013-03-05
US61/772,885 2013-03-05
PCT/US2014/020858 WO2014138279A1 (en) 2013-03-05 2014-03-05 Compounds for treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019017755A Division JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Publications (3)

Publication Number Publication Date
JP2016510748A JP2016510748A (ja) 2016-04-11
JP2016510748A5 true JP2016510748A5 (OSRAM) 2017-04-06
JP6835472B2 JP6835472B2 (ja) 2021-02-24

Family

ID=51491914

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015561618A Expired - Fee Related JP6835472B2 (ja) 2013-03-05 2014-03-05 癌の処置のための組成物
JP2019017755A Pending JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019017755A Pending JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Country Status (11)

Country Link
US (2) US10022356B2 (OSRAM)
EP (1) EP2964028A4 (OSRAM)
JP (2) JP6835472B2 (OSRAM)
KR (1) KR102246652B1 (OSRAM)
CN (2) CN109568312A (OSRAM)
AU (2) AU2014225761B2 (OSRAM)
CA (1) CA2904338C (OSRAM)
IL (1) IL241232B (OSRAM)
MX (2) MX375059B (OSRAM)
RU (1) RU2708247C2 (OSRAM)
WO (1) WO2014138279A1 (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
LT2303021T (lt) * 2008-06-16 2019-06-25 University Of Tennessee Research Foundation Junginiai, skirti vėžio gydymui
US9029408B2 (en) * 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
CN109568312A (zh) 2013-03-05 2019-04-05 田纳西大学研究基金会 用于治疗癌症的化合物
MX379271B (es) 2014-05-06 2025-03-11 Gtx Inc Compuestos desestabilizadores de microtubulina para usarse en el tratamiento del cáncer.
CN104434924B (zh) * 2014-11-10 2016-09-14 暨南大学 曲美替尼在制备逆转肿瘤多药耐药性药物中的应用
ES2827024T3 (es) * 2014-12-23 2021-05-19 Dot Therapeutics 1 Inc Combinación de inhibidores de Raf y de taxanos
EP3256473A4 (en) * 2015-02-12 2018-08-01 Memorial Sloan Kettering Cancer Center Synergistic cancer treatment
IL256111B2 (en) * 2015-06-05 2023-09-01 Univ Illinois Treatment of pac combinations
AR105483A1 (es) 2015-06-30 2017-10-11 Exelixis Inc Sal de fumarato cristalina de (s)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil][3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona
AU2015401587A1 (en) * 2015-07-09 2018-02-01 The Jackson Laboratory Methods of treating cancer by administering a MEK inhibitor in combination with a proteasome inhibitor
ES2992827T3 (en) * 2015-08-06 2024-12-18 Wistar Inst Combination therapies targeting mitochondrial biogenesis for cancer therapy
CA3017963A1 (en) 2016-03-16 2017-09-21 Dicerna Pharmaceuticals, Inc. Compositions and methods for the treatment of a beta-catenin-associated disease or disorder
WO2017200826A1 (en) * 2016-05-16 2017-11-23 Albert Einstein College Of Medicine, Inc. Assays and compounds for treatment of cancer
US11040027B2 (en) 2017-01-17 2021-06-22 Heparegenix Gmbh Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death
WO2018164262A1 (ja) * 2017-03-10 2018-09-13 コニカミノルタ株式会社 治療有効性の予測方法
JP7291399B2 (ja) * 2017-05-03 2023-06-15 ティン セラピューティクス エルエルシー 難聴の予防および治療のための組成物および方法
SG11202004384YA (en) 2017-11-17 2020-06-29 Univ Illinois Cancer therapy by degrading dual mek signaling
CN108218855A (zh) * 2018-03-12 2018-06-29 桑文军 一种新型微管蛋白抑制剂及其在抗肿瘤药物中的应用
WO2019222392A1 (en) * 2018-05-15 2019-11-21 University Of Tennessee Research Foundation Compounds for treatment of pancreatic cancer
EP3793549A4 (en) * 2018-05-15 2022-03-09 University of Tennessee Research Foundation COMPOUNDS FOR THE TREATMENT OF TRIPLE NEGATIVE BREAST CANCER AND OVARIAN CANCER
WO2020072774A1 (en) 2018-10-05 2020-04-09 The Board Of Trustees Of The University Of Illinois Combination therapy for the treatment of uveal melanoma
GB201913124D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
BR112022015161A2 (pt) * 2020-01-31 2022-10-11 Verastem Inc Terapia de combinação para tratamento de crescimento celular anormal
CN113440616A (zh) * 2020-03-25 2021-09-28 上海科州药物研发有限公司 Ras或raf突变型癌症的联合疗法
US20230355581A1 (en) * 2020-07-02 2023-11-09 The Board of Regents of the Unversity of Texas System Methods of treatment for melanoma
WO2022067185A1 (en) * 2020-09-27 2022-03-31 Veru Inc. Methods of treating prostate cancer with minimal side effects
WO2022131667A1 (ko) * 2020-12-18 2022-06-23 경희대학교 산학협력단 Oligodendrocyte transcription factor 2 억제제를 유효성분으로 포함하는 흑색종 치료 효과 증진용 약학적 조성물
CN115504964A (zh) * 2022-04-12 2022-12-23 海创药业股份有限公司 氘代杂环酮类化合物及其用途
CN117143081B (zh) * 2022-05-24 2025-08-01 赣南医科大学 一种Sabizabulin的制备方法
WO2024036114A2 (en) * 2022-08-08 2024-02-15 The Regents Of The University Of California Combination therapy including cox-2 inhibitor for the treatment of cancer
WO2024186641A1 (en) * 2023-03-03 2024-09-12 Onconova Therapeutics, Inc. Methods and compositions for treating cancer
CN119409641A (zh) * 2024-11-05 2025-02-11 杭州电子科技大学 一种磺酰基衍生物和用途

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
DK0934937T3 (da) 1990-11-30 2002-04-02 Otsuka Pharma Co Ltd Azolderivater som superoxidradikalinhibitor
US5120749A (en) 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
JP2550915B2 (ja) 1994-06-21 1996-11-06 日本電気株式会社 印刷配線板の表面保護剤および表面保護膜の形成方法
DK1347971T3 (da) 2000-12-21 2006-05-15 Bristol Myers Squibb Co Thiazolylinhibitorer af tyrosinkinaser fra Tec-familien
US20040267017A1 (en) 2001-09-26 2004-12-30 Bierer Donald E 3-pyridyl or 4-isoquinolinyl thiazoles as c17, 20 lyase inhibitors
JP2005532983A (ja) 2001-09-26 2005-11-04 バイエル・フアーマシユーチカルズ・コーポレーシヨン Ｃ１７，２０リアーゼ阻害剤としての３‐ピリジルもしくは４‐イソキノリニルチアゾール
FR2831536A1 (fr) 2001-10-26 2003-05-02 Aventis Pharma Sa Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
EP1456187A4 (en) 2001-11-15 2005-02-09 Incyte San Diego Inc N-SUBSTITUTED HETEROCYCLES FOR THE TREATMENT OF HYPERCHOLESTERINEMIA, DYSLIPIDEMIA AND OTHER METABOLIC DISORDER, CANCER AND OTHER DISEASES
CN1747936A (zh) 2003-02-12 2006-03-15 特兰斯泰克制药公司 作为治疗试剂的取代吡咯衍生物
EP1613313B1 (en) 2003-04-17 2007-06-06 Janssen Pharmaceutica N.V. 2-phenyl-benzimidazol and 2-phenyl-imidazo-4,5]-pyridine derivatives as checkpoint kinase cds1 (chk2) inhibitors for the treatment of cancer
JP2007500219A (ja) 2003-05-16 2007-01-11 アンビット バイオサイエンシス コーポレーション 複素環化合物およびその使用法
EP1692121A1 (en) 2003-11-18 2006-08-23 University of Tennessee Research Foundation Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof
JP2007516258A (ja) 2003-12-12 2007-06-21 ワイス 心臓血管の疾患治療に有用なキノリン誘導体
CA2557650A1 (en) 2004-03-08 2005-09-22 Wyeth Ion channel modulators
EP2027853A3 (en) 2004-06-18 2011-01-05 Agennix USA Inc. Kinase inhibitors for treating cancers
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
UA95244C2 (ru) * 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
US7612212B2 (en) * 2006-02-22 2009-11-03 Hoffmann-La Roche Inc. Substituted hydantoins
EP2025347A4 (en) 2006-05-15 2010-08-11 Takeda Pharmaceutical PROPHYLACTIC AND THERAPEUTIC AGENTS AGAINST CANCER
US7464893B2 (en) * 2006-06-30 2008-12-16 Per Spjut Method of using a cord holder
KR100932093B1 (ko) 2006-09-27 2009-12-16 주식회사종근당 미세소관 형성 저해제로서 유용한 벤조페논 유도체
US8822513B2 (en) * 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9029408B2 (en) * 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
LT2303021T (lt) 2008-06-16 2019-06-25 University Of Tennessee Research Foundation Junginiai, skirti vėžio gydymui
US9334242B2 (en) * 2008-06-16 2016-05-10 Gtx, Inc. Compounds for treatment of cancer
US9447049B2 (en) * 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
SI2488033T1 (sl) * 2009-10-16 2019-10-30 Novartis Ag Kombinacija, ki vsebuje inhibitor MEK in inhibitor B-RAF
WO2012027716A1 (en) 2010-08-27 2012-03-01 Collabrx, Inc. Method to treat melanoma in braf inhibitor-resistant subjects
KR101418229B1 (ko) 2011-03-29 2014-07-09 미쓰비시덴키 가부시키가이샤 서보 제어 장치의 이상 진단 장치 및 이상 진단 시스템
SG10201504303SA (en) * 2011-04-01 2015-07-30 Genentech Inc Combinations Of AKT Inhibitor Compounds And Chemotherapeutic Agents, And Methods Of Use
SI2694510T1 (sl) * 2011-04-07 2016-02-29 Bayer Intellectual Property Gmbh Imidazopiridazini kot inhibitorji AKT kinaze
CN109568312A (zh) * 2013-03-05 2019-04-05 田纳西大学研究基金会 用于治疗癌症的化合物

Similar Documents

Publication Publication Date Title
JP2016510748A5 (OSRAM)
RU2015142102A (ru) Соединение для лечения рака
Girnun et al. Synergy between PPARγ ligands and platinum-based drugs in cancer
JP2009514880A5 (OSRAM)
JP2009514881A5 (OSRAM)
JP2013521281A5 (OSRAM)
JP2013508288A5 (OSRAM)
JP2017530176A5 (OSRAM)
JP2018510851A5 (OSRAM)
JP2013507415A5 (OSRAM)
JP2013531038A (ja) 癌の治療のための低酸素活性化プロドラッグおよび血管新生阻害剤の投与方法
JP2018507191A5 (OSRAM)
JP2016513137A5 (OSRAM)
JP2010522194A5 (OSRAM)
JP2014508811A5 (OSRAM)
JP2017530984A5 (OSRAM)
JP2013537203A5 (OSRAM)
JP2016502544A5 (OSRAM)
EA201690322A1 (ru) Терапевтически активные соединения и способы их применения
JP2016503414A5 (OSRAM)
JP2019529518A5 (OSRAM)
PH12012500504A1 (en) N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine in the treatment of antimitotic agent resistent cancer
JP2017511321A5 (OSRAM)
JP2017534583A5 (OSRAM)
JP2020502094A5 (OSRAM)