JP2016508143A5 - - Google Patents
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- Publication number
- JP2016508143A5 JP2016508143A5 JP2015551157A JP2015551157A JP2016508143A5 JP 2016508143 A5 JP2016508143 A5 JP 2016508143A5 JP 2015551157 A JP2015551157 A JP 2015551157A JP 2015551157 A JP2015551157 A JP 2015551157A JP 2016508143 A5 JP2016508143 A5 JP 2016508143A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- polypeptide
- amino acid
- seq
- pharmaceutically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000037865 fusion proteins Human genes 0.000 claims 10
- 108020001507 fusion proteins Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 102000019034 Chemokines Human genes 0.000 claims 1
- 108010012236 Chemokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 229960000182 blood factors Drugs 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13150171.0 | 2013-01-03 | ||
| EP13150171.0A EP2752426A1 (en) | 2013-01-03 | 2013-01-03 | Human serum albumin binding compounds and fusion proteins thereof |
| PCT/EP2013/077227 WO2014106583A1 (en) | 2013-01-03 | 2013-12-18 | Human serum albumin binding compounds and fusion proteins thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016508143A JP2016508143A (ja) | 2016-03-17 |
| JP2016508143A5 true JP2016508143A5 (cg-RX-API-DMAC7.html) | 2017-01-12 |
Family
ID=47458817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551157A Pending JP2016508143A (ja) | 2013-01-03 | 2013-12-18 | ヒト血清アルブミン結合化合物およびその融合タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9790475B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2752426A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016508143A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013372004B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2896962A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1215441A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014106583A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016534984A (ja) | 2013-10-01 | 2016-11-10 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | アフィニティークロマトグラフィーのためおよび治療薬の半減期の延長のための化合物 |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| HRP20250319T1 (hr) | 2017-02-16 | 2025-05-09 | Sonnet BioTherapeutics, Inc. | Fuzijski proteini s domenom za vezanje na albumin |
| CN107353346A (zh) * | 2017-08-09 | 2017-11-17 | 芜湖英特菲尔生物制品产业研究院有限公司 | 一种由猪白蛋白与猪干扰素γ组成的融合蛋白及其制备方法和一种重组猪长效干扰素γ |
| CN113710229A (zh) | 2019-02-25 | 2021-11-26 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| EP4106798A1 (en) | 2020-02-17 | 2022-12-28 | Biotest AG | Subcutaneous administration of factor viii |
| JP7754510B2 (ja) * | 2020-03-06 | 2025-10-15 | ユニバーシティ オブ ピッツバーグ －オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 血清アルブミン結合ナノボディ組成物、及びその使用方法 |
| CN116284375A (zh) * | 2020-08-14 | 2023-06-23 | 上海洛启生物医药技术有限公司 | 非pH依赖性长效型抗血清白蛋白纳米抗体及其应用 |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6080560A (en) | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| CA2921260A1 (en) | 1999-12-24 | 2001-06-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| US7211395B2 (en) | 2001-03-09 | 2007-05-01 | Dyax Corp. | Serum albumin binding moieties |
| EP3299393A1 (en) | 2002-11-08 | 2018-03-28 | Ablynx N.V. | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| EP1892248A1 (en) * | 2006-08-21 | 2008-02-27 | Eidgenössische Technische Hochschule Zürich | Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase |
| EP2524927A1 (en) * | 2011-05-20 | 2012-11-21 | Covagen AG | New chymase binding compounds and medical uses thereof |
| WO2013135588A1 (en) * | 2012-03-16 | 2013-09-19 | Covagen Ag | Novel binding molecules with antitumoral activity |
-
2013
- 2013-01-03 EP EP13150171.0A patent/EP2752426A1/en not_active Withdrawn
- 2013-12-18 US US14/758,339 patent/US9790475B2/en not_active Expired - Fee Related
- 2013-12-18 EP EP13821463.0A patent/EP2941439B1/en not_active Not-in-force
- 2013-12-18 CA CA2896962A patent/CA2896962A1/en not_active Abandoned
- 2013-12-18 HK HK16103286.9A patent/HK1215441A1/zh unknown
- 2013-12-18 WO PCT/EP2013/077227 patent/WO2014106583A1/en not_active Ceased
- 2013-12-18 AU AU2013372004A patent/AU2013372004B2/en not_active Ceased
- 2013-12-18 JP JP2015551157A patent/JP2016508143A/ja active Pending
-
2017
- 2017-09-25 US US15/714,444 patent/US10364419B2/en not_active Expired - Fee Related