JP2016507543A5 - - Google Patents
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- JP2016507543A5 JP2016507543A5 JP2015556499A JP2015556499A JP2016507543A5 JP 2016507543 A5 JP2016507543 A5 JP 2016507543A5 JP 2015556499 A JP2015556499 A JP 2015556499A JP 2015556499 A JP2015556499 A JP 2015556499A JP 2016507543 A5 JP2016507543 A5 JP 2016507543A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- vesicle
- bacterial
- animal
- associated antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 11
- 230000001580 bacterial effect Effects 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 241001465754 Metazoa Species 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 102000012406 Carcinoembryonic Antigen Human genes 0.000 claims 2
- 108010022366 Carcinoembryonic Antigen Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 230000003412 degenerative effect Effects 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 244000052769 pathogen Species 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 239000000232 Lipid Bilayer Substances 0.000 claims 1
- 102000016200 MART-1 Antigen Human genes 0.000 claims 1
- 108010010995 MART-1 Antigen Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 102000003735 Mesothelin Human genes 0.000 claims 1
- 108090000015 Mesothelin Proteins 0.000 claims 1
- -1 Silv Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13154463.7 | 2013-02-07 | ||
| EP13154463 | 2013-02-07 | ||
| PCT/EP2014/052370 WO2014122232A1 (en) | 2013-02-07 | 2014-02-06 | Pharmaceutical compositions comprising vesicles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016507543A JP2016507543A (ja) | 2016-03-10 |
| JP2016507543A5 true JP2016507543A5 (https=) | 2017-03-09 |
Family
ID=47681775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556499A Pending JP2016507543A (ja) | 2013-02-07 | 2014-02-06 | 小胞を含む医薬組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20160120818A1 (https=) |
| EP (1) | EP2953620A1 (https=) |
| JP (1) | JP2016507543A (https=) |
| CN (1) | CN105163724A (https=) |
| BR (1) | BR112015018877A2 (https=) |
| CA (1) | CA2900454A1 (https=) |
| WO (1) | WO2014122232A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102396026B1 (ko) * | 2014-01-21 | 2022-05-09 | 안자리움 바이오사이언시스 아게 | 하이브리도좀, 이를 포함하는 조성물, 이의 제조 방법 및 이의 용도 |
| AU2015326407C1 (en) * | 2014-10-03 | 2021-06-24 | Engeneic Molecular Delivery Pty Ltd | Enhanced loading of intact, bacterially derived vesicles with small molecule compounds |
| AU2017226956A1 (en) * | 2016-03-03 | 2018-10-11 | Institut Gustave Roussy | PTPS-based vaccines against cancer |
| CN110248645B (zh) * | 2016-12-29 | 2022-04-26 | 韩国科学技术研究院 | 基于外来体的抗癌剂 |
| EP3678693A1 (en) | 2017-09-08 | 2020-07-15 | Evelo Biosciences, Inc. | Bacterial extracellular vesicles |
| BR102018008194A2 (pt) * | 2018-04-24 | 2020-07-07 | Universidade De São Paulo - Usp. | kit farmacêutico e seus usos |
| WO2019210189A1 (en) * | 2018-04-26 | 2019-10-31 | University Of Louisville Research Foundation, Inc. | Edible plant exosome-like nanovectors for vaccination |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| US12397047B2 (en) * | 2019-01-09 | 2025-08-26 | Exocure Sweden Ab | Bacteria-derived vesicles and uses thereof |
| CN110367202B (zh) * | 2019-06-20 | 2021-11-02 | 广东医科大学附属医院 | 一种肠菌外膜囊泡在制备痴呆动物模型中的应用 |
| US20220378902A1 (en) * | 2019-08-22 | 2022-12-01 | Sichuan University | Bacterial membrane vesicles, and separation and preparation system and method therefor |
| EP4013392B1 (en) | 2019-09-13 | 2026-04-29 | Exocure Sweden AB | Use of ghost nanovesicles as therapeutics |
| CN111521826A (zh) * | 2020-05-21 | 2020-08-11 | 江海松 | 外周血外泌体中Notch3蛋白作为分子标记的应用及一种检测试剂盒 |
| WO2022154149A1 (ko) * | 2021-01-14 | 2022-07-21 | (주)엑솔런스 | 세포외소포체를 이용한 백신 조성물 |
| WO2023097652A1 (en) * | 2021-12-03 | 2023-06-08 | National Center For Nanoscience And Technology | An engineered cell and application thereof |
| KR20240010702A (ko) * | 2022-07-13 | 2024-01-24 | (주)엑솔런스 | 항원 단백질 또는 상기 단백질을 암호화하는 유전자를포함하는 세포외소포체 및 그의 용도 |
| CN115350161B (zh) * | 2022-08-19 | 2024-04-16 | 沈阳药科大学 | 基于工程化益生菌外膜囊泡包被纳米酶递送系统及其制备方法和应用 |
| CN117065041B (zh) * | 2023-04-04 | 2024-02-27 | 山东大学 | 一种包被载药脂质纳米粒的外膜囊泡及其制备方法和应用 |
| CN120789140B (zh) * | 2025-09-12 | 2026-04-10 | 湖北医药学院 | 一种治疗结肠炎的联合用药物及其应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
| US6645503B1 (en) | 1998-03-10 | 2003-11-11 | Wyeth Holdings Corporation | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| AU762369B2 (en) | 1998-11-03 | 2003-06-26 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur | LPS with reduced toxicity from genetically modified gram negative bacteria |
| US6531131B1 (en) | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
| AU1917501A (en) | 1999-11-12 | 2001-06-06 | University Of Iowa Research Foundation, The | Control of neisserial membrane synthesis |
| PT2289545T (pt) * | 2000-01-17 | 2016-09-06 | Glaxosmithkline Biologicals Sa | Vacina de omv suplementada contra meningococos |
| NO20002828D0 (no) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav |
| ES2519440T3 (es) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vacunas para la protección de amplio espectro contra enfermedades causadas por Neisseria meningitidis |
| GB0130123D0 (en) * | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
| US20060057160A1 (en) | 2002-08-02 | 2006-03-16 | Ralph Biemans | Vaccine composition |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| DK2992901T3 (da) * | 2004-02-02 | 2020-01-27 | Engeneic Molecular Delivery Pty Ltd | Sammensætninger og fremgangsmåder til målrettet in vitro- og in vivo-medicinlevering til pattedyrceller via bakterielt afledte intakte miniceller |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0424092D0 (en) * | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| WO2006081259A2 (en) | 2005-01-27 | 2006-08-03 | Children's Hospital & Research Center At Oakland | Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
| EP2254586B1 (en) * | 2008-02-22 | 2015-04-08 | Agency For Science, Technology And Research (A*star) | Mesenchymal stem cell particles |
| CN102596177B (zh) * | 2009-07-01 | 2014-05-28 | 阿昂梅迪克斯公司 | 来源于有核哺乳动物细胞的微囊泡及其应用 |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
-
2014
- 2014-02-06 JP JP2015556499A patent/JP2016507543A/ja active Pending
- 2014-02-06 CN CN201480017087.1A patent/CN105163724A/zh active Pending
- 2014-02-06 BR BR112015018877A patent/BR112015018877A2/pt not_active IP Right Cessation
- 2014-02-06 CA CA2900454A patent/CA2900454A1/en not_active Abandoned
- 2014-02-06 EP EP14705488.6A patent/EP2953620A1/en not_active Withdrawn
- 2014-02-06 US US14/766,202 patent/US20160120818A1/en not_active Abandoned
- 2014-02-06 WO PCT/EP2014/052370 patent/WO2014122232A1/en not_active Ceased
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